Maximising value from a United Kingdom Biomedical Research Centre: study protocol View Full Text


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Article Info

DATE

2017-08-14

AUTHORS

Trisha Greenhalgh, Pavel V. Ovseiko, Nick Fahy, Sara Shaw, Polly Kerr, Alexander D. Rushforth, Keith M. Channon, Vasiliki Kiparoglou, On behalf of the Partnerships for Health, Wealth and Innovation cross-cutting theme of the National Institute for Health Research Biomedical Research Centre, Oxford

ABSTRACT

BackgroundBiomedical Research Centres (BRCs) are partnerships between healthcare organisations and universities in England. Their mission is to generate novel treatments, technologies, diagnostics and other interventions that increase the country’s international competitiveness, to rapidly translate these innovations into benefits for patients, and to improve efficiency and reduce waste in healthcare. As NIHR Oxford BRC (Oxford BRC) enters its third 5-year funding period, we seek to (1) apply the evidence base on how best to support the various partnerships in this large, multi-stakeholder research system and (2) research how these partnerships play out in a new, ambitious programme of translational research.MethodsOrganisational case study, informed by the principles of action research. A cross-cutting theme, ‘Partnerships for Health, Wealth and Innovation’ has been established with multiple sub-themes (drug development, device development, business support and commercialisation, research methodology and statistics, health economics, bioethics, patient and public involvement and engagement, knowledge translation, and education and training) to support individual BRC research themes and generate cross-theme learning.The ‘Partnerships’ theme will support the BRC’s goals by facilitating six types of partnership (with patients and citizens, clinical services, industry, across the NIHR infrastructure, across academic disciplines, and with policymakers and payers) through a range of engagement platforms and activities. We will develop a longitudinal progress narrative centred around exemplar case studies, and apply theoretical models from innovation studies (Triple Helix), sociology of science (Mode 2 knowledge production) and business studies (Value Co-creation). Data sources will be the empirical research studies within individual BRC research themes (who will apply separately for NHS ethics approval), plus documentary analysis and interviews and ethnography with research stakeholders. This study has received ethics clearance through the University of Oxford Central University Research Ethics Committee.DiscussionWe anticipate that this work will add significant value to Oxford BRC. We predict accelerated knowledge translation; closer alignment of the innovation process with patient priorities and the principles of responsible, ethical research; reduction in research waste; new knowledge about the governance and activities of multi-stakeholder research partnerships and the contexts in which they operate; and capacity-building that reflects the future needs of a rapidly-evolving health research system. More... »

PAGES

70

References to SciGraph publications

  • 2015-07-30. A realist evaluation of community-based participatory research: partnership synergy, trust building and related ripple effects in BMC PUBLIC HEALTH
  • 2017-01-10. A manifesto for reproducible science in NATURE HUMAN BEHAVIOUR
  • 2010-05-13. Who needs what from a national health research system:lessons from reforms to the English Department of Health's R&D system in HEALTH RESEARCH POLICY AND SYSTEMS
  • 2014-11-08. Implementation of collaborative governance in cross-sector innovation and education networks: evidence from the National Health Service in England in BMC HEALTH SERVICES RESEARCH
  • 2016-12-28. Building health research systems: WHO is generating global perspectives, and who’s celebrating national successes? in HEALTH RESEARCH POLICY AND SYSTEMS
  • 2012. Mode 3 Knowledge Production in Quadruple Helix Innovation Systems, 21st-Century Democracy, Innovation, and Entrepreneurship for Development in NONE
  • 2012-12-23. Assessing research impact in academic clinical medicine: a study using Research Excellence Framework pilot impact indicators in BMC HEALTH SERVICES RESEARCH
  • 2017-01-21. Does a biomedical research centre affect patient care in local hospitals? in HEALTH RESEARCH POLICY AND SYSTEMS
  • 2014-01-20. Improving accountability through alignment: the role of academic health science centres and networks in England in BMC HEALTH SERVICES RESEARCH
  • 2003-09. Introduction: `Mode 2' Revisited: The New Production of Knowledge in MINERVA
  • 2017-02-02. Economies of scale and scope in publicly funded biomedical and health research: evidence from the literature in HEALTH RESEARCH POLICY AND SYSTEMS
  • 2015-09-16. An introduction to implementation science for the non-specialist in BMC PSYCHOLOGY
  • 2011-11-04. Mode 3 Knowledge Production in Quadruple Helix Innovation Systems in MODE 3 KNOWLEDGE PRODUCTION IN QUADRUPLE HELIX INNOVATION SYSTEMS
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    PUBMED

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    25 schema:description BackgroundBiomedical Research Centres (BRCs) are partnerships between healthcare organisations and universities in England. Their mission is to generate novel treatments, technologies, diagnostics and other interventions that increase the country’s international competitiveness, to rapidly translate these innovations into benefits for patients, and to improve efficiency and reduce waste in healthcare. As NIHR Oxford BRC (Oxford BRC) enters its third 5-year funding period, we seek to (1) apply the evidence base on how best to support the various partnerships in this large, multi-stakeholder research system and (2) research how these partnerships play out in a new, ambitious programme of translational research.MethodsOrganisational case study, informed by the principles of action research. A cross-cutting theme, ‘Partnerships for Health, Wealth and Innovation’ has been established with multiple sub-themes (drug development, device development, business support and commercialisation, research methodology and statistics, health economics, bioethics, patient and public involvement and engagement, knowledge translation, and education and training) to support individual BRC research themes and generate cross-theme learning.The ‘Partnerships’ theme will support the BRC’s goals by facilitating six types of partnership (with patients and citizens, clinical services, industry, across the NIHR infrastructure, across academic disciplines, and with policymakers and payers) through a range of engagement platforms and activities. We will develop a longitudinal progress narrative centred around exemplar case studies, and apply theoretical models from innovation studies (Triple Helix), sociology of science (Mode 2 knowledge production) and business studies (Value Co-creation). Data sources will be the empirical research studies within individual BRC research themes (who will apply separately for NHS ethics approval), plus documentary analysis and interviews and ethnography with research stakeholders. This study has received ethics clearance through the University of Oxford Central University Research Ethics Committee.DiscussionWe anticipate that this work will add significant value to Oxford BRC. We predict accelerated knowledge translation; closer alignment of the innovation process with patient priorities and the principles of responsible, ethical research; reduction in research waste; new knowledge about the governance and activities of multi-stakeholder research partnerships and the contexts in which they operate; and capacity-building that reflects the future needs of a rapidly-evolving health research system.
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