Splenic marginal zone lymphoma: a case report and literature review View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-10-01

AUTHORS

Shiyu Zhang, Zefeng Xuan, Liang Zhang, Jiahua Lu, Penghong Song, Shusen Zheng

ABSTRACT

BackgroundSplenic marginal zone lymphoma (SMZL) is a rare non-Hodgkin lymphoma, and much little is known about its clinical characteristics and management strategies. Here we present a case of SMZL and review relevant literature to provide a better recognition of this disease entity.Case presentationA 49-year-old Chinese female was admitted to our hospital with complaints of abdominal distension and acid reflux. Physical examinations and imaging investigations suggested the presence of splenomegaly. Laboratory workups revealed mildly reduced white blood cell count otherwise was not remarkable. The patient underwent splenectomy. Histological examination combined with immunohistochemical analysis of the resected spleen confirmed the diagnosis of SMZL. The patient recovered uneventfully during follow-ups.ConclusionsDue to the rarity and unspecific clinical features, SMZL is extremely challenging to be diagnosed preoperatively. Patients with SMZL are generally associated with favorable prognosis. Combining the staging characteristics of non-Hodgkin’s lymphoma and splenic primary lymphoma may assist in clinical staging management of SMZL. More... »

PAGES

259

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12957-020-02030-3

DOI

http://dx.doi.org/10.1186/s12957-020-02030-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1131364828

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33004051


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