Long-term survival of high-grade primary peritoneal papillary serous adenocarcinoma: a case report and literature review View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Jingping Yuan, Liang He, Bing Han, Yan Li

ABSTRACT

BACKGROUND: Primary peritoneal papillary serous carcinoma (PPPSC) is an uncommon disease which has a high malignancy and a poor prognosis. CASE PRESENTATION: We report here a long-term survival case of PPPSC with postoperative lung metastasis. A 62-year-old female patient with PPPSC was administered two cycles of neoadjuvant chemotherapy (NAC) followed by cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and six cycles of platinum-based (docetaxel + carboplatin) intraperitoneal chemotherapy postoperatively. The patient reached a complete remission at the completion of primary treatment. Malignant thoracic effusion and lung metastasis developed 5 months after the treatment. The patient underwent video-assisted thoracoscopic surgery plus hyperthermic intrapleural chemotherapy. CONCLUSIONS: Up to present, the patient has been survived with tumor for over 86 months with a good performance status, with only encapsulated effusion found at the latest follow-up. As a relatively new regime, the application of CRS + HIPEC in our patient has been proved example for MPE management, although more large-scale studies are needed to substantiate its efficiency and safety. More... »

PAGES

76

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12957-017-1134-3

DOI

http://dx.doi.org/10.1186/s12957-017-1134-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084737907

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28399919


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