Ontology type: schema:ScholarlyArticle Open Access: True
2019-12
AUTHORSHanchen Xu, Chunyan Wang, Haiyan Song, Yangxian Xu, Guang Ji
ABSTRACTIn this study, the secondary sequencing was used to profile circRNA expression in the tissue samples from three CRC patients with liver metastasis and three matched CRC patients. After verified some candidates in another 40 CRC and CRC-m samples by qRT-PCR, we further demonstrated that circRNA_0001178 and circRNA_0000826 were significantly upregulated in CRC-m tissues, and both of them had the potential for diagnosing liver metastases from colorectal cancer. Finally, the networks of circRNA-miRNA-mRNA base on these two circRNAs were constructed respectively. This study showed that differentially expressed circRNAs were existed between the tissue samples from colorectal cancer patients with and without liver metastasis. And also suggested that circRNA_0001178 and circRNA_0000826 may serve as a potential diagnostic biomarker for liver metastases from colorectal cancer. More... »
PAGES8
http://scigraph.springernature.com/pub.10.1186/s12943-018-0932-8
DOIhttp://dx.doi.org/10.1186/s12943-018-0932-8
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1111329585
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30630466
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Shanghai University of Traditional Chinese Medicine",
"id": "https://www.grid.ac/institutes/grid.412540.6",
"name": [
"Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, China"
],
"type": "Organization"
},
"familyName": "Xu",
"givenName": "Hanchen",
"id": "sg:person.015645137565.57",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015645137565.57"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Shanghai University of Traditional Chinese Medicine",
"id": "https://www.grid.ac/institutes/grid.412540.6",
"name": [
"Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, China"
],
"type": "Organization"
},
"familyName": "Wang",
"givenName": "Chunyan",
"id": "sg:person.014122166051.25",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014122166051.25"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Shanghai University of Traditional Chinese Medicine",
"id": "https://www.grid.ac/institutes/grid.412540.6",
"name": [
"Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, China"
],
"type": "Organization"
},
"familyName": "Song",
"givenName": "Haiyan",
"id": "sg:person.0775077234.79",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775077234.79"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Shanghai University of Traditional Chinese Medicine",
"id": "https://www.grid.ac/institutes/grid.412540.6",
"name": [
"Department of General Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, China"
],
"type": "Organization"
},
"familyName": "Xu",
"givenName": "Yangxian",
"id": "sg:person.01106666745.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106666745.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Shanghai University of Traditional Chinese Medicine",
"id": "https://www.grid.ac/institutes/grid.412540.6",
"name": [
"Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, China"
],
"type": "Organization"
},
"familyName": "Ji",
"givenName": "Guang",
"id": "sg:person.01111325634.82",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111325634.82"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/nature11928",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004715472",
"https://doi.org/10.1038/nature11928"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncomms11215",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047094596",
"https://doi.org/10.1038/ncomms11215"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11993",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050833467",
"https://doi.org/10.1038/nature11993"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/s41598-018-21300-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1100901854",
"https://doi.org/10.1038/s41598-018-21300-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12943-018-0833-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1103744423",
"https://doi.org/10.1186/s12943-018-0833-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12943-018-0833-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1103744423",
"https://doi.org/10.1186/s12943-018-0833-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12943-018-0888-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107120999",
"https://doi.org/10.1186/s12943-018-0888-8"
],
"type": "CreativeWork"
}
],
"datePublished": "2019-12",
"datePublishedReg": "2019-12-01",
"description": "In this study, the secondary sequencing was used to profile circRNA expression in the tissue samples from three CRC patients with liver metastasis and three matched CRC patients. After verified some candidates in another 40 CRC and CRC-m samples by qRT-PCR, we further demonstrated that circRNA_0001178 and circRNA_0000826 were significantly upregulated in CRC-m tissues, and both of them had the potential for diagnosing liver metastases from colorectal cancer. Finally, the networks of circRNA-miRNA-mRNA base on these two circRNAs were constructed respectively. This study showed that differentially expressed circRNAs were existed between the tissue samples from colorectal cancer patients with and without liver metastasis. And also suggested that circRNA_0001178 and circRNA_0000826 may serve as a potential diagnostic biomarker for liver metastases from colorectal cancer.",
"genre": "non_research_article",
"id": "sg:pub.10.1186/s12943-018-0932-8",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1031030",
"issn": [
"1476-4598"
],
"name": "Molecular Cancer",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "18"
}
],
"name": "RNA-Seq profiling of circular RNAs in human colorectal Cancer liver metastasis and the potential biomarkers",
"pagination": "8",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"f4ba5ed9a86c3eab27dec273fdde09ddad896acb58bec790cdf28efdc1744212"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30630466"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101147698"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s12943-018-0932-8"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1111329585"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s12943-018-0932-8",
"https://app.dimensions.ai/details/publication/pub.1111329585"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T08:41",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000320_0000000320/records_101369_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1186%2Fs12943-018-0932-8"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0932-8'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0932-8'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0932-8'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0932-8'
This table displays all metadata directly associated to this object as RDF triples.
121 TRIPLES
21 PREDICATES
35 URIs
21 LITERALS
9 BLANK NODES