Ontology type: schema:ScholarlyArticle Open Access: True
2018-12
AUTHORSWeiwei Tang, Kai Fu, Handong Sun, Dawei Rong, Hanjin Wang, Hongyong Cao
ABSTRACTCircRNA expression profiles for gastric cancer (GC) were screened using plasma samples from 10 GC patients with different TNM stages and 5 healthy individuals as controls. Results showed lower expression of circ-KIAA1244 in GC tissues, plasmas, and cells compare to normal controls. Further clinical data analysis demonstrated that a decreased expression of circ-KIAA1244 in plasmas was negatively correlated with TNM stage and lymphatic metastasis, and a shorter overall survival time of GC patients. Moreover, we found that circ-KIAA1244 could be detected in GC plasma exosomes and showed no obvious significance compared to the expression level in the corresponding plasmas. This study revealed a GC-tissues-derived circ-KIAA1244 could serve a novel circulating biomarker for detection of GC. More... »
PAGES137
http://scigraph.springernature.com/pub.10.1186/s12943-018-0888-8
DOIhttp://dx.doi.org/10.1186/s12943-018-0888-8
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1107120999
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30236115
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"name": [
"Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China"
],
"type": "Organization"
},
"familyName": "Tang",
"givenName": "Weiwei",
"id": "sg:person.01312034033.90",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312034033.90"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China"
],
"type": "Organization"
},
"familyName": "Fu",
"givenName": "Kai",
"id": "sg:person.010613730527.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010613730527.02"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China"
],
"type": "Organization"
},
"familyName": "Sun",
"givenName": "Handong",
"id": "sg:person.015126460327.29",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015126460327.29"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China"
],
"type": "Organization"
},
"familyName": "Rong",
"givenName": "Dawei",
"id": "sg:person.012262420043.76",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012262420043.76"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China"
],
"type": "Organization"
},
"familyName": "Wang",
"givenName": "Hanjin",
"id": "sg:person.010361164443.80",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010361164443.80"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of general surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China"
],
"type": "Organization"
},
"familyName": "Cao",
"givenName": "Hongyong",
"id": "sg:person.012206671527.97",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012206671527.97"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/cr.2015.82",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022611802",
"https://doi.org/10.1038/cr.2015.82"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/srep37982",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031022444",
"https://doi.org/10.1038/srep37982"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/15476286.2015.1020271",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058402967"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12943-018-0827-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1103148642",
"https://doi.org/10.1186/s12943-018-0827-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12943-018-0827-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1103148642",
"https://doi.org/10.1186/s12943-018-0827-8"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12943-018-0827-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1103148642",
"https://doi.org/10.1186/s12943-018-0827-8"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.18632/genesandcancer.172",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1104417213"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.molcel.2018.06.034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105857811"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.molcel.2018.06.034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105857811"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.molcel.2018.06.034",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1105857811"
],
"type": "CreativeWork"
}
],
"datePublished": "2018-12",
"datePublishedReg": "2018-12-01",
"description": "CircRNA expression profiles for gastric cancer (GC) were screened using plasma samples from 10 GC patients with different TNM stages and 5 healthy individuals as controls. Results showed lower expression of circ-KIAA1244 in GC tissues, plasmas, and cells compare to normal controls. Further clinical data analysis demonstrated that a decreased expression of circ-KIAA1244 in plasmas was negatively correlated with TNM stage and lymphatic metastasis, and a shorter overall survival time of GC patients. Moreover, we found that circ-KIAA1244 could be detected in GC plasma exosomes and showed no obvious significance compared to the expression level in the corresponding plasmas. This study revealed a GC-tissues-derived circ-KIAA1244 could serve a novel circulating biomarker for detection of GC.",
"genre": "non_research_article",
"id": "sg:pub.10.1186/s12943-018-0888-8",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1031030",
"issn": [
"1476-4598"
],
"name": "Molecular Cancer",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "17"
}
],
"name": "CircRNA microarray profiling identifies a novel circulating biomarker for detection of gastric cancer",
"pagination": "137",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"d07891b5feec7a01a2eedba7a4787a81ac0c18b583155f484cc8437f88ca95ca"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30236115"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101147698"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s12943-018-0888-8"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1107120999"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s12943-018-0888-8",
"https://app.dimensions.ai/details/publication/pub.1107120999"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T19:14",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000540.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1186%2Fs12943-018-0888-8"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0888-8'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0888-8'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0888-8'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0888-8'
This table displays all metadata directly associated to this object as RDF triples.
133 TRIPLES
21 PREDICATES
35 URIs
21 LITERALS
9 BLANK NODES