Circular RNAs function as ceRNAs to regulate and control human cancer progression View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Yaxian Zhong, Yajun Du, Xue Yang, Yongzhen Mo, Chunmei Fan, Fang Xiong, Daixi Ren, Xin Ye, Chunwei Li, Yumin Wang, Fang Wei, Can Guo, Xu Wu, Xiaoling Li, Yong Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong

ABSTRACT

Circular RNAs (circRNAs) are connected at the 3' and 5' ends by exon or intron cyclization, forming a complete ring structure. circRNA is more stable and conservative than linear RNA and abounds in various organisms. In recent years, increasing numbers of reports have found that circRNA plays a major role in the biological functions of a network of competing endogenous RNA (ceRNA). circRNAs can compete together with microRNAs (miRNAs) to influence the stability of target RNAs or their translation, thus, regulating gene expression at the transcriptional level. circRNAs are involved in biological processes such as tumor cell proliferation, apoptosis, invasion, and migration as ceRNAs. circRNAs, therefore, represent promising candidates for clinical diagnosis and treatment. Here, we review the progress in studying the role of circRNAs as ceRNAs in tumors and highlight the participation of circRNAs in signal transduction pathways to regulate cellular functions. More... »

PAGES

79

References to SciGraph publications

  • 2011-09. MicroRNAs can generate thresholds in target gene expression in NATURE GENETICS
  • 2016-01. AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis in TUMOR BIOLOGY
  • 2015-08. Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis in CELL RESEARCH
  • 2017-01. The circular RNA ciRS-7 (Cdr1as) acts as a risk factor of hepatic microvascular invasion in hepatocellular carcinoma in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 2018-02-01. Circular RNAs in cancer: opportunities and challenges in the field in ONCOGENE
  • 2017-12. Role of long non-coding RNAs in glucose metabolism in cancer in MOLECULAR CANCER
  • 2017-08-10. circRNA_100290 plays a role in oral cancer by functioning as a sponge of the miR-29 family in ONCOGENE
  • 2014-01. The multilayered complexity of ceRNA crosstalk and competition in NATURE
  • 2017-12. circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
  • 2009-03. Cell cycle, CDKs and cancer: a changing paradigm in NATURE REVIEWS CANCER
  • 2017-12. TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2006-12. Editor meets silencer: crosstalk between RNA editing and RNA interference in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2018-03. MicroRNAs and metastasis: small RNAs play big roles in CANCER AND METASTASIS REVIEWS
  • 2014-01. HMGA2 functions as a competing endogenous RNA to promote lung cancer progression in NATURE
  • 2018-01. Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM in CELL DEATH & DIFFERENTIATION
  • 2017-12. Circular RNAs in human cancer in MOLECULAR CANCER
  • 2016-01. Converging roles of caspases in inflammasome activation, cell death and innate immunity in NATURE REVIEWS IMMUNOLOGY
  • 2014-07. Expanded identification and characterization of mammalian circular RNAs in GENOME BIOLOGY
  • 2016-12. EMT, cell plasticity and metastasis in CANCER AND METASTASIS REVIEWS
  • 2016-11. Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma in SCIENTIFIC REPORTS
  • 2015-02. Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives in TUMOR BIOLOGY
  • 2014-07. p53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation in ONCOGENE
  • 2002-12. Inflammation and cancer in NATURE
  • 2016-03. An integrative transcriptomic analysis reveals p53 regulated miRNA, mRNA, and lncRNA networks in nasopharyngeal carcinoma in TUMOR BIOLOGY
  • 2013-12. VEGF targets the tumour cell in NATURE REVIEWS CANCER
  • 2013-03. Circular RNAs are a large class of animal RNAs with regulatory potency in NATURE
  • 2014-03. Aberrant ceRNA activity drives lung cancer in CELL RESEARCH
  • 2016-04-06. Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs in NATURE COMMUNICATIONS
  • 2018-03. Molecular roles and function of circular RNAs in eukaryotic cells in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2013-03. Natural RNA circles function as efficient microRNA sponges in NATURE
  • 2017-03-29. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome in NATURE
  • 2016-09. Epstein-Barr virus-encoded miR-BART6-3p inhibits cancer cell metastasis and invasion by targeting long non-coding RNA LOC553103 in CELL DEATH & DISEASE
  • 2013-03. Neuroprotection of Interleukin-6 Against NMDA-induced Neurotoxicity is Mediated by JAK/STAT3, MAPK/ERK, and PI3K/AKT Signaling Pathways in CELLULAR AND MOLECULAR NEUROBIOLOGY
  • 2017-12. Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer in MOLECULAR CANCER
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12943-018-0827-8

    DOI

    http://dx.doi.org/10.1186/s12943-018-0827-8

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1103148642

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29626935


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhong", 
            "givenName": "Yaxian", 
            "id": "sg:person.010427415744.57", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010427415744.57"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Du", 
            "givenName": "Yajun", 
            "id": "sg:person.012022356744.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012022356744.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yang", 
            "givenName": "Xue", 
            "id": "sg:person.016335106544.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016335106544.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mo", 
            "givenName": "Yongzhen", 
            "id": "sg:person.012357652313.70", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012357652313.70"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fan", 
            "givenName": "Chunmei", 
            "id": "sg:person.010562230267.54", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010562230267.54"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Xiong", 
            "givenName": "Fang", 
            "id": "sg:person.014315502431.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014315502431.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ren", 
            "givenName": "Daixi", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ye", 
            "givenName": "Xin", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Chunwei", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wang", 
            "givenName": "Yumin", 
            "id": "sg:person.016556431515.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016556431515.68"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wei", 
            "givenName": "Fang", 
            "id": "sg:person.0636002262.86", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636002262.86"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Guo", 
            "givenName": "Can", 
            "id": "sg:person.011446321315.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011446321315.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wu", 
            "givenName": "Xu", 
            "id": "sg:person.010700046752.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010700046752.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China", 
                "Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Xiaoling", 
            "id": "sg:person.01077226116.59", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077226116.59"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cleveland Clinic", 
              "id": "https://www.grid.ac/institutes/grid.239578.2", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China", 
                "Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Yong", 
            "id": "sg:person.012000605407.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012000605407.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China", 
                "Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Guiyuan", 
            "id": "sg:person.0765070774.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765070774.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China", 
                "Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zeng", 
            "givenName": "Zhaoyang", 
            "id": "sg:person.01062616162.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062616162.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Central South University", 
              "id": "https://www.grid.ac/institutes/grid.216417.7", 
              "name": [
                "The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China", 
                "The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China", 
                "Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Xiong", 
            "givenName": "Wei", 
            "id": "sg:person.01300760777.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300760777.46"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/ng.905", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000209603", 
              "https://doi.org/10.1038/ng.905"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hep.25576", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001476125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/sj.emboj.7600481", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001730749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7150/jca.14663", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002067362"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1812509", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002397028"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00432-016-2256-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002576904", 
              "https://doi.org/10.1007/s00432-016-2256-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00432-016-2256-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002576904", 
              "https://doi.org/10.1007/s00432-016-2256-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/b978-0-12-386497-0.00006-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003419794"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11928", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004715472", 
              "https://doi.org/10.1038/nature11928"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2012.05.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005670808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2016.12.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006245560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0148407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006865115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0148407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006865115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0148407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006865115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc2602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008867916", 
              "https://doi.org/10.1038/nrc2602"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.8589", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011130290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc3627", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011267322", 
              "https://doi.org/10.1038/nrc3627"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-014-0409-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012100318", 
              "https://doi.org/10.1186/s13059-014-0409-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-014-0409-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012100318", 
              "https://doi.org/10.1186/s13059-014-0409-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/md.0000000000003811", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012643610"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/md.0000000000003811", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012643610"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri.2015.7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014186753", 
              "https://doi.org/10.1038/nri.2015.7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.9170", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014985992"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.73.11.3852", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015010966"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m804280200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016182430"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10571-012-9891-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017013288", 
              "https://doi.org/10.1007/s10571-012-9891-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10555-016-9648-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018653131", 
              "https://doi.org/10.1007/s10555-016-9648-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10555-016-9648-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018653131", 
              "https://doi.org/10.1007/s10555-016-9648-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.01484-08", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018747032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01322", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019336134", 
              "https://doi.org/10.1038/nature01322"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01322", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019336134", 
              "https://doi.org/10.1038/nature01322"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.5759", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019641849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/2159-8290.cd-13-0202", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021245915"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2013.355", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022240351", 
              "https://doi.org/10.1038/onc.2013.355"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cr.2015.82", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022611802", 
              "https://doi.org/10.1038/cr.2015.82"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkl151", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023012861"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2011.02.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023540354"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.14200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024251194"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.14200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024251194"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12986", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025529308", 
              "https://doi.org/10.1038/nature12986"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-015-3093-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025945004", 
              "https://doi.org/10.1007/s13277-015-3093-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2009.06.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025957515"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12688/f1000research.3872.1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029079693"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12688/f1000research.3872.1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029079693"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2016/1579490", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030988506"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep30919", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033215371", 
              "https://doi.org/10.1038/srep30919"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci44745", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033395023"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkw027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034341236"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.devcel.2011.06.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036249060"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.4057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037067376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.4057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037067376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbadis.2009.12.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039210635"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.celrep.2016.03.058", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039942747"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12785", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043182133", 
              "https://doi.org/10.1038/nature12785"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.1222509110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044271395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1078-0432.ccr-05-2250", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044803980"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms11215", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047094596", 
              "https://doi.org/10.1038/ncomms11215"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0158347", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047724816"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2015.03.027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048300891"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cr.2014.21", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048410586", 
              "https://doi.org/10.1038/cr.2014.21"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-015-3860-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048600988", 
              "https://doi.org/10.1007/s13277-015-3860-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0096718", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048630792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0096718", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048630792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.00251-12", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049303859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4137/bbi.s28991", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049612043"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-015-4156-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050783282", 
              "https://doi.org/10.1007/s13277-015-4156-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13277-015-4156-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050783282", 
              "https://doi.org/10.1007/s13277-015-4156-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11993", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050833467", 
              "https://doi.org/10.1038/nature11993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052425587", 
              "https://doi.org/10.1038/nrm2061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052425587", 
              "https://doi.org/10.1038/nrm2061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj20030407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052909234"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj20030407", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052909234"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hep.25572", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052934488"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2011.07.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053021425"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ccell.2015.03.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053023000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2016.253", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053257073", 
              "https://doi.org/10.1038/cddis.2016.253"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cddis.2016.253", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053257073", 
              "https://doi.org/10.1038/cddis.2016.253"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/15476286.2016.1269999", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058403185"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/15548627.2016.1239676", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058406792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3748/wjg.v21.i41.11680", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071373126"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2304", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532295"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2013.2304", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071532295"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3892/or.2016.4971", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071534674"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1096/fasebj.7.1.7678559", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1082462833"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0598-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083399670", 
              "https://doi.org/10.1186/s12943-017-0598-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0598-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083399670", 
              "https://doi.org/10.1186/s12943-017-0598-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0612-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083847159", 
              "https://doi.org/10.1186/s12943-017-0612-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0612-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083847159", 
              "https://doi.org/10.1186/s12943-017-0612-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13045-017-0422-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083851320", 
              "https://doi.org/10.1186/s13045-017-0422-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13045-017-0422-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083851320", 
              "https://doi.org/10.1186/s13045-017-0422-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7150/jca.17510", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084002493"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature21715", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084128605", 
              "https://doi.org/10.1038/nature21715"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-16-1883", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084230787"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.16104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084373221"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.16709", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084373817"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/ijms18030597", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084435893"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2017.89", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084508981", 
              "https://doi.org/10.1038/onc.2017.89"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2147/ott.s131597", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084757463"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hep.29270", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085431373"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.26201", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085994045"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2017.05.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086035985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jvi.00301-17", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086132819"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jvi.00301-17", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086132819"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.18671", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090278615"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ymthe.2017.05.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090309465"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2017.06.027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090351344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/febs.14132", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090363403"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molcel.2017.07.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090835253"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0699-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090885746", 
              "https://doi.org/10.1186/s12943-017-0699-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12943-017-0699-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090885746", 
              "https://doi.org/10.1186/s12943-017-0699-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djx166", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090966640"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jnci/djx166", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090966640"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/dna.2017.3862", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091931278"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.18671", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092090480"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/onc.2017.361", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092132006", 
              "https://doi.org/10.1038/onc.2017.361"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18632/oncotarget.21830", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092231237"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13046-017-0614-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092239386", 
              "https://doi.org/10.1186/s13046-017-0614-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2017.11.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092547368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2017.11.028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092547368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00018-017-2688-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092573923", 
              "https://doi.org/10.1007/s00018-017-2688-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/cdd.2017.172", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092619107", 
              "https://doi.org/10.1038/cdd.2017.172"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10555-017-9712-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1099702627", 
              "https://doi.org/10.1007/s10555-017-9712-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10555-017-9712-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1099702627", 
              "https://doi.org/10.1007/s10555-017-9712-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10555-017-9712-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1099702627", 
              "https://doi.org/10.1007/s10555-017-9712-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3389/fimmu.2018.00009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1100554902"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-12", 
        "datePublishedReg": "2018-12-01", 
        "description": "Circular RNAs (circRNAs) are connected at the 3' and 5' ends by exon or intron cyclization, forming a complete ring structure. circRNA is more stable and conservative than linear RNA and abounds in various organisms. In recent years, increasing numbers of reports have found that circRNA plays a major role in the biological functions of a network of competing endogenous RNA (ceRNA). circRNAs can compete together with microRNAs (miRNAs) to influence the stability of target RNAs or their translation, thus, regulating gene expression at the transcriptional level. circRNAs are involved in biological processes such as tumor cell proliferation, apoptosis, invasion, and migration as ceRNAs. circRNAs, therefore, represent promising candidates for clinical diagnosis and treatment. Here, we review the progress in studying the role of circRNAs as ceRNAs in tumors and highlight the participation of circRNAs in signal transduction pathways to regulate cellular functions.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/s12943-018-0827-8", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1031030", 
            "issn": [
              "1476-4598"
            ], 
            "name": "Molecular Cancer", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "17"
          }
        ], 
        "name": "Circular RNAs function as ceRNAs to regulate and control human cancer progression", 
        "pagination": "79", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "b2403afb24728861ed4938ab457e079c6f4504402d5e17b80f2980570df49630"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "29626935"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101147698"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s12943-018-0827-8"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1103148642"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s12943-018-0827-8", 
          "https://app.dimensions.ai/details/publication/pub.1103148642"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T14:21", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000372_0000000372/records_117125_00000003.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1186%2Fs12943-018-0827-8"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0827-8'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0827-8'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0827-8'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12943-018-0827-8'


     

    This table displays all metadata directly associated to this object as RDF triples.

    524 TRIPLES      21 PREDICATES      128 URIs      21 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s12943-018-0827-8 schema:about anzsrc-for:06
    2 anzsrc-for:0601
    3 schema:author N55288ed3eb774265857f3ea9bc1cf379
    4 schema:citation sg:pub.10.1007/s00018-017-2688-5
    5 sg:pub.10.1007/s00432-016-2256-7
    6 sg:pub.10.1007/s10555-016-9648-7
    7 sg:pub.10.1007/s10555-017-9712-y
    8 sg:pub.10.1007/s10571-012-9891-6
    9 sg:pub.10.1007/s13277-015-3093-z
    10 sg:pub.10.1007/s13277-015-3860-x
    11 sg:pub.10.1007/s13277-015-4156-x
    12 sg:pub.10.1038/cdd.2017.172
    13 sg:pub.10.1038/cddis.2016.253
    14 sg:pub.10.1038/cr.2014.21
    15 sg:pub.10.1038/cr.2015.82
    16 sg:pub.10.1038/nature01322
    17 sg:pub.10.1038/nature11928
    18 sg:pub.10.1038/nature11993
    19 sg:pub.10.1038/nature12785
    20 sg:pub.10.1038/nature12986
    21 sg:pub.10.1038/nature21715
    22 sg:pub.10.1038/ncomms11215
    23 sg:pub.10.1038/ng.905
    24 sg:pub.10.1038/nrc2602
    25 sg:pub.10.1038/nrc3627
    26 sg:pub.10.1038/nri.2015.7
    27 sg:pub.10.1038/nrm2061
    28 sg:pub.10.1038/onc.2013.355
    29 sg:pub.10.1038/onc.2017.361
    30 sg:pub.10.1038/onc.2017.89
    31 sg:pub.10.1038/srep30919
    32 sg:pub.10.1186/s12943-017-0598-7
    33 sg:pub.10.1186/s12943-017-0612-0
    34 sg:pub.10.1186/s12943-017-0699-3
    35 sg:pub.10.1186/s13045-017-0422-2
    36 sg:pub.10.1186/s13046-017-0614-1
    37 sg:pub.10.1186/s13059-014-0409-z
    38 https://doi.org/10.1002/hep.25572
    39 https://doi.org/10.1002/hep.25576
    40 https://doi.org/10.1002/hep.29270
    41 https://doi.org/10.1002/jcb.26201
    42 https://doi.org/10.1016/b978-0-12-386497-0.00006-2
    43 https://doi.org/10.1016/j.bbadis.2009.12.009
    44 https://doi.org/10.1016/j.bbrc.2017.11.028
    45 https://doi.org/10.1016/j.canlet.2016.12.006
    46 https://doi.org/10.1016/j.canlet.2017.06.027
    47 https://doi.org/10.1016/j.ccell.2015.03.001
    48 https://doi.org/10.1016/j.cell.2009.06.016
    49 https://doi.org/10.1016/j.cell.2011.02.013
    50 https://doi.org/10.1016/j.cell.2011.07.014
    51 https://doi.org/10.1016/j.cell.2012.05.012
    52 https://doi.org/10.1016/j.celrep.2016.03.058
    53 https://doi.org/10.1016/j.devcel.2011.06.017
    54 https://doi.org/10.1016/j.molcel.2015.03.027
    55 https://doi.org/10.1016/j.molcel.2017.05.023
    56 https://doi.org/10.1016/j.molcel.2017.07.005
    57 https://doi.org/10.1016/j.ymthe.2017.05.022
    58 https://doi.org/10.1038/sj.emboj.7600481
    59 https://doi.org/10.1042/bj20030407
    60 https://doi.org/10.1073/pnas.1222509110
    61 https://doi.org/10.1073/pnas.73.11.3852
    62 https://doi.org/10.1074/jbc.m804280200
    63 https://doi.org/10.1080/15476286.2016.1269999
    64 https://doi.org/10.1080/15548627.2016.1239676
    65 https://doi.org/10.1089/dna.2017.3862
    66 https://doi.org/10.1093/jnci/djx166
    67 https://doi.org/10.1093/nar/gkl151
    68 https://doi.org/10.1093/nar/gkw027
    69 https://doi.org/10.1096/fasebj.7.1.7678559
    70 https://doi.org/10.1097/md.0000000000003811
    71 https://doi.org/10.1101/gad.1812509
    72 https://doi.org/10.1111/febs.14132
    73 https://doi.org/10.1128/jvi.00301-17
    74 https://doi.org/10.1128/mcb.00251-12
    75 https://doi.org/10.1128/mcb.01484-08
    76 https://doi.org/10.1155/2016/1579490
    77 https://doi.org/10.1158/0008-5472.can-16-1883
    78 https://doi.org/10.1158/1078-0432.ccr-05-2250
    79 https://doi.org/10.1158/2159-8290.cd-13-0202
    80 https://doi.org/10.1172/jci44745
    81 https://doi.org/10.12688/f1000research.3872.1
    82 https://doi.org/10.1371/journal.pone.0096718
    83 https://doi.org/10.1371/journal.pone.0148407
    84 https://doi.org/10.1371/journal.pone.0158347
    85 https://doi.org/10.18632/oncotarget.14200
    86 https://doi.org/10.18632/oncotarget.16104
    87 https://doi.org/10.18632/oncotarget.16709
    88 https://doi.org/10.18632/oncotarget.18671
    89 https://doi.org/10.18632/oncotarget.21830
    90 https://doi.org/10.18632/oncotarget.4057
    91 https://doi.org/10.18632/oncotarget.5759
    92 https://doi.org/10.18632/oncotarget.8589
    93 https://doi.org/10.18632/oncotarget.9170
    94 https://doi.org/10.2147/ott.s131597
    95 https://doi.org/10.3389/fimmu.2018.00009
    96 https://doi.org/10.3390/ijms18030597
    97 https://doi.org/10.3748/wjg.v21.i41.11680
    98 https://doi.org/10.3892/or.2013.2304
    99 https://doi.org/10.3892/or.2016.4971
    100 https://doi.org/10.4137/bbi.s28991
    101 https://doi.org/10.7150/jca.14663
    102 https://doi.org/10.7150/jca.17510
    103 schema:datePublished 2018-12
    104 schema:datePublishedReg 2018-12-01
    105 schema:description Circular RNAs (circRNAs) are connected at the 3' and 5' ends by exon or intron cyclization, forming a complete ring structure. circRNA is more stable and conservative than linear RNA and abounds in various organisms. In recent years, increasing numbers of reports have found that circRNA plays a major role in the biological functions of a network of competing endogenous RNA (ceRNA). circRNAs can compete together with microRNAs (miRNAs) to influence the stability of target RNAs or their translation, thus, regulating gene expression at the transcriptional level. circRNAs are involved in biological processes such as tumor cell proliferation, apoptosis, invasion, and migration as ceRNAs. circRNAs, therefore, represent promising candidates for clinical diagnosis and treatment. Here, we review the progress in studying the role of circRNAs as ceRNAs in tumors and highlight the participation of circRNAs in signal transduction pathways to regulate cellular functions.
    106 schema:genre research_article
    107 schema:inLanguage en
    108 schema:isAccessibleForFree true
    109 schema:isPartOf N0585871845ee4c1abb9b0369a301d09c
    110 N427e7b6fa66a465ca9d94c2ac201ee19
    111 sg:journal.1031030
    112 schema:name Circular RNAs function as ceRNAs to regulate and control human cancer progression
    113 schema:pagination 79
    114 schema:productId N0a270d3ff7d048c084537c9c8a20776c
    115 N1570cd8bb7ce483b8f9ded8d4d241fa4
    116 N8ab97b896bcd421493accce4b5e13cf6
    117 Nc24a711bb8054525ac05384f533f8758
    118 Ne1828b3f31864c14925f71e7f15dacdb
    119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103148642
    120 https://doi.org/10.1186/s12943-018-0827-8
    121 schema:sdDatePublished 2019-04-11T14:21
    122 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    123 schema:sdPublisher Nafd00f1fb1e841a489d61a4541f7340a
    124 schema:url https://link.springer.com/10.1186%2Fs12943-018-0827-8
    125 sgo:license sg:explorer/license/
    126 sgo:sdDataset articles
    127 rdf:type schema:ScholarlyArticle
    128 N0585871845ee4c1abb9b0369a301d09c schema:issueNumber 1
    129 rdf:type schema:PublicationIssue
    130 N0a270d3ff7d048c084537c9c8a20776c schema:name pubmed_id
    131 schema:value 29626935
    132 rdf:type schema:PropertyValue
    133 N1570cd8bb7ce483b8f9ded8d4d241fa4 schema:name readcube_id
    134 schema:value b2403afb24728861ed4938ab457e079c6f4504402d5e17b80f2980570df49630
    135 rdf:type schema:PropertyValue
    136 N15ab8314aa0549699783c69d00d6ff16 rdf:first sg:person.014315502431.53
    137 rdf:rest N8446146bf5b74592b9d125c2bec93ec3
    138 N206d2a16210d40e48a3b728bbd241c2d schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    139 schema:familyName Ren
    140 schema:givenName Daixi
    141 rdf:type schema:Person
    142 N22d315fad363407b87d305870c75c025 rdf:first sg:person.012000605407.96
    143 rdf:rest N8a7fdfa9a44c43c1b91f7ecbd682f13d
    144 N26fc110277fd4279967d1554e45a1ec6 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    145 schema:familyName Ye
    146 schema:givenName Xin
    147 rdf:type schema:Person
    148 N345c7d01910545cab4b5c2788b827932 rdf:first Neae529d57aaa4c06b0d7778c289d16cd
    149 rdf:rest N965552123b624e1497962b7e963c54dc
    150 N427e7b6fa66a465ca9d94c2ac201ee19 schema:volumeNumber 17
    151 rdf:type schema:PublicationVolume
    152 N55288ed3eb774265857f3ea9bc1cf379 rdf:first sg:person.010427415744.57
    153 rdf:rest Naae82aafe2924621800910da1a7a7b3b
    154 N55d04fdde2054ab59a3ccb6f71f17912 rdf:first sg:person.011446321315.42
    155 rdf:rest Nf84412ae3fc940e4a3706a9e851f0b9c
    156 N579e7597a18f45bdb3a5f3fd9634a8eb rdf:first sg:person.01077226116.59
    157 rdf:rest N22d315fad363407b87d305870c75c025
    158 N6c28f6cfa91d461c9956c3988ad0d008 rdf:first sg:person.012357652313.70
    159 rdf:rest Nafcf30b38b2044bc81a530fe068aafb1
    160 N8446146bf5b74592b9d125c2bec93ec3 rdf:first N206d2a16210d40e48a3b728bbd241c2d
    161 rdf:rest Nc6519d67b5f8402cad14f2d56e5fd32d
    162 N84db46c084994cc6b55f4b48c060198d rdf:first sg:person.016335106544.22
    163 rdf:rest N6c28f6cfa91d461c9956c3988ad0d008
    164 N8a7fdfa9a44c43c1b91f7ecbd682f13d rdf:first sg:person.0765070774.37
    165 rdf:rest Na3e27b625a4849d9900ec77eca37f911
    166 N8ab97b896bcd421493accce4b5e13cf6 schema:name dimensions_id
    167 schema:value pub.1103148642
    168 rdf:type schema:PropertyValue
    169 N965552123b624e1497962b7e963c54dc rdf:first sg:person.016556431515.68
    170 rdf:rest Nf32234493039448a8837a5aad2bc382e
    171 N9ee05cec41c04bc0ade093fb96da6d24 rdf:first sg:person.01300760777.46
    172 rdf:rest rdf:nil
    173 Na3e27b625a4849d9900ec77eca37f911 rdf:first sg:person.01062616162.23
    174 rdf:rest N9ee05cec41c04bc0ade093fb96da6d24
    175 Na8eb0116320a4e8fa0fb2082e5101c6a schema:name The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China
    176 rdf:type schema:Organization
    177 Naae82aafe2924621800910da1a7a7b3b rdf:first sg:person.012022356744.00
    178 rdf:rest N84db46c084994cc6b55f4b48c060198d
    179 Nafcf30b38b2044bc81a530fe068aafb1 rdf:first sg:person.010562230267.54
    180 rdf:rest N15ab8314aa0549699783c69d00d6ff16
    181 Nafd00f1fb1e841a489d61a4541f7340a schema:name Springer Nature - SN SciGraph project
    182 rdf:type schema:Organization
    183 Nc24a711bb8054525ac05384f533f8758 schema:name doi
    184 schema:value 10.1186/s12943-018-0827-8
    185 rdf:type schema:PropertyValue
    186 Nc6519d67b5f8402cad14f2d56e5fd32d rdf:first N26fc110277fd4279967d1554e45a1ec6
    187 rdf:rest N345c7d01910545cab4b5c2788b827932
    188 Ne1828b3f31864c14925f71e7f15dacdb schema:name nlm_unique_id
    189 schema:value 101147698
    190 rdf:type schema:PropertyValue
    191 Neae529d57aaa4c06b0d7778c289d16cd schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    192 schema:familyName Li
    193 schema:givenName Chunwei
    194 rdf:type schema:Person
    195 Nf32234493039448a8837a5aad2bc382e rdf:first sg:person.0636002262.86
    196 rdf:rest N55d04fdde2054ab59a3ccb6f71f17912
    197 Nf84412ae3fc940e4a3706a9e851f0b9c rdf:first sg:person.010700046752.98
    198 rdf:rest N579e7597a18f45bdb3a5f3fd9634a8eb
    199 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    200 schema:name Biological Sciences
    201 rdf:type schema:DefinedTerm
    202 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    203 schema:name Biochemistry and Cell Biology
    204 rdf:type schema:DefinedTerm
    205 sg:journal.1031030 schema:issn 1476-4598
    206 schema:name Molecular Cancer
    207 rdf:type schema:Periodical
    208 sg:person.010427415744.57 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    209 schema:familyName Zhong
    210 schema:givenName Yaxian
    211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010427415744.57
    212 rdf:type schema:Person
    213 sg:person.010562230267.54 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    214 schema:familyName Fan
    215 schema:givenName Chunmei
    216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010562230267.54
    217 rdf:type schema:Person
    218 sg:person.01062616162.23 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    219 schema:familyName Zeng
    220 schema:givenName Zhaoyang
    221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062616162.23
    222 rdf:type schema:Person
    223 sg:person.010700046752.98 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    224 schema:familyName Wu
    225 schema:givenName Xu
    226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010700046752.98
    227 rdf:type schema:Person
    228 sg:person.01077226116.59 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    229 schema:familyName Li
    230 schema:givenName Xiaoling
    231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077226116.59
    232 rdf:type schema:Person
    233 sg:person.011446321315.42 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    234 schema:familyName Guo
    235 schema:givenName Can
    236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011446321315.42
    237 rdf:type schema:Person
    238 sg:person.012000605407.96 schema:affiliation https://www.grid.ac/institutes/grid.239578.2
    239 schema:familyName Li
    240 schema:givenName Yong
    241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012000605407.96
    242 rdf:type schema:Person
    243 sg:person.012022356744.00 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    244 schema:familyName Du
    245 schema:givenName Yajun
    246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012022356744.00
    247 rdf:type schema:Person
    248 sg:person.012357652313.70 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    249 schema:familyName Mo
    250 schema:givenName Yongzhen
    251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012357652313.70
    252 rdf:type schema:Person
    253 sg:person.01300760777.46 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    254 schema:familyName Xiong
    255 schema:givenName Wei
    256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300760777.46
    257 rdf:type schema:Person
    258 sg:person.014315502431.53 schema:affiliation Na8eb0116320a4e8fa0fb2082e5101c6a
    259 schema:familyName Xiong
    260 schema:givenName Fang
    261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014315502431.53
    262 rdf:type schema:Person
    263 sg:person.016335106544.22 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    264 schema:familyName Yang
    265 schema:givenName Xue
    266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016335106544.22
    267 rdf:type schema:Person
    268 sg:person.016556431515.68 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    269 schema:familyName Wang
    270 schema:givenName Yumin
    271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016556431515.68
    272 rdf:type schema:Person
    273 sg:person.0636002262.86 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    274 schema:familyName Wei
    275 schema:givenName Fang
    276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636002262.86
    277 rdf:type schema:Person
    278 sg:person.0765070774.37 schema:affiliation https://www.grid.ac/institutes/grid.216417.7
    279 schema:familyName Li
    280 schema:givenName Guiyuan
    281 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765070774.37
    282 rdf:type schema:Person
    283 sg:pub.10.1007/s00018-017-2688-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092573923
    284 https://doi.org/10.1007/s00018-017-2688-5
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1007/s00432-016-2256-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002576904
    287 https://doi.org/10.1007/s00432-016-2256-7
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1007/s10555-016-9648-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018653131
    290 https://doi.org/10.1007/s10555-016-9648-7
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1007/s10555-017-9712-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1099702627
    293 https://doi.org/10.1007/s10555-017-9712-y
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1007/s10571-012-9891-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017013288
    296 https://doi.org/10.1007/s10571-012-9891-6
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1007/s13277-015-3093-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1025945004
    299 https://doi.org/10.1007/s13277-015-3093-z
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1007/s13277-015-3860-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048600988
    302 https://doi.org/10.1007/s13277-015-3860-x
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1007/s13277-015-4156-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050783282
    305 https://doi.org/10.1007/s13277-015-4156-x
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/cdd.2017.172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092619107
    308 https://doi.org/10.1038/cdd.2017.172
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/cddis.2016.253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053257073
    311 https://doi.org/10.1038/cddis.2016.253
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/cr.2014.21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048410586
    314 https://doi.org/10.1038/cr.2014.21
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1038/cr.2015.82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022611802
    317 https://doi.org/10.1038/cr.2015.82
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1038/nature01322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019336134
    320 https://doi.org/10.1038/nature01322
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1038/nature11928 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004715472
    323 https://doi.org/10.1038/nature11928
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1038/nature11993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050833467
    326 https://doi.org/10.1038/nature11993
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1038/nature12785 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043182133
    329 https://doi.org/10.1038/nature12785
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1038/nature12986 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025529308
    332 https://doi.org/10.1038/nature12986
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1038/nature21715 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128605
    335 https://doi.org/10.1038/nature21715
    336 rdf:type schema:CreativeWork
    337 sg:pub.10.1038/ncomms11215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047094596
    338 https://doi.org/10.1038/ncomms11215
    339 rdf:type schema:CreativeWork
    340 sg:pub.10.1038/ng.905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000209603
    341 https://doi.org/10.1038/ng.905
    342 rdf:type schema:CreativeWork
    343 sg:pub.10.1038/nrc2602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008867916
    344 https://doi.org/10.1038/nrc2602
    345 rdf:type schema:CreativeWork
    346 sg:pub.10.1038/nrc3627 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011267322
    347 https://doi.org/10.1038/nrc3627
    348 rdf:type schema:CreativeWork
    349 sg:pub.10.1038/nri.2015.7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014186753
    350 https://doi.org/10.1038/nri.2015.7
    351 rdf:type schema:CreativeWork
    352 sg:pub.10.1038/nrm2061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052425587
    353 https://doi.org/10.1038/nrm2061
    354 rdf:type schema:CreativeWork
    355 sg:pub.10.1038/onc.2013.355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022240351
    356 https://doi.org/10.1038/onc.2013.355
    357 rdf:type schema:CreativeWork
    358 sg:pub.10.1038/onc.2017.361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092132006
    359 https://doi.org/10.1038/onc.2017.361
    360 rdf:type schema:CreativeWork
    361 sg:pub.10.1038/onc.2017.89 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084508981
    362 https://doi.org/10.1038/onc.2017.89
    363 rdf:type schema:CreativeWork
    364 sg:pub.10.1038/srep30919 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033215371
    365 https://doi.org/10.1038/srep30919
    366 rdf:type schema:CreativeWork
    367 sg:pub.10.1186/s12943-017-0598-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083399670
    368 https://doi.org/10.1186/s12943-017-0598-7
    369 rdf:type schema:CreativeWork
    370 sg:pub.10.1186/s12943-017-0612-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083847159
    371 https://doi.org/10.1186/s12943-017-0612-0
    372 rdf:type schema:CreativeWork
    373 sg:pub.10.1186/s12943-017-0699-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090885746
    374 https://doi.org/10.1186/s12943-017-0699-3
    375 rdf:type schema:CreativeWork
    376 sg:pub.10.1186/s13045-017-0422-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083851320
    377 https://doi.org/10.1186/s13045-017-0422-2
    378 rdf:type schema:CreativeWork
    379 sg:pub.10.1186/s13046-017-0614-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092239386
    380 https://doi.org/10.1186/s13046-017-0614-1
    381 rdf:type schema:CreativeWork
    382 sg:pub.10.1186/s13059-014-0409-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1012100318
    383 https://doi.org/10.1186/s13059-014-0409-z
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1002/hep.25572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052934488
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1002/hep.25576 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001476125
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1002/hep.29270 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085431373
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1002/jcb.26201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085994045
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1016/b978-0-12-386497-0.00006-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003419794
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1016/j.bbadis.2009.12.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039210635
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1016/j.bbrc.2017.11.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092547368
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1016/j.canlet.2016.12.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006245560
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1016/j.canlet.2017.06.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090351344
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1016/j.ccell.2015.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053023000
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1016/j.cell.2009.06.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025957515
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1016/j.cell.2011.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023540354
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1016/j.cell.2011.07.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053021425
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1016/j.cell.2012.05.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005670808
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1016/j.celrep.2016.03.058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039942747
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1016/j.devcel.2011.06.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036249060
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1016/j.molcel.2015.03.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048300891
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1016/j.molcel.2017.05.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086035985
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1016/j.molcel.2017.07.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090835253
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1016/j.ymthe.2017.05.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090309465
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1038/sj.emboj.7600481 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001730749
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1042/bj20030407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052909234
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1073/pnas.1222509110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044271395
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1073/pnas.73.11.3852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015010966
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1074/jbc.m804280200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016182430
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1080/15476286.2016.1269999 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058403185
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1080/15548627.2016.1239676 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058406792
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1089/dna.2017.3862 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091931278
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1093/jnci/djx166 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090966640
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1093/nar/gkl151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023012861
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1093/nar/gkw027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034341236
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1096/fasebj.7.1.7678559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082462833
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1097/md.0000000000003811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012643610
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1101/gad.1812509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002397028
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1111/febs.14132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090363403
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.1128/jvi.00301-17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086132819
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.1128/mcb.00251-12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049303859
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.1128/mcb.01484-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018747032
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.1155/2016/1579490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030988506
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.1158/0008-5472.can-16-1883 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084230787
    464 rdf:type schema:CreativeWork
    465 https://doi.org/10.1158/1078-0432.ccr-05-2250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044803980
    466 rdf:type schema:CreativeWork
    467 https://doi.org/10.1158/2159-8290.cd-13-0202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021245915
    468 rdf:type schema:CreativeWork
    469 https://doi.org/10.1172/jci44745 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033395023
    470 rdf:type schema:CreativeWork
    471 https://doi.org/10.12688/f1000research.3872.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029079693
    472 rdf:type schema:CreativeWork
    473 https://doi.org/10.1371/journal.pone.0096718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048630792
    474 rdf:type schema:CreativeWork
    475 https://doi.org/10.1371/journal.pone.0148407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006865115
    476 rdf:type schema:CreativeWork
    477 https://doi.org/10.1371/journal.pone.0158347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047724816
    478 rdf:type schema:CreativeWork
    479 https://doi.org/10.18632/oncotarget.14200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024251194
    480 rdf:type schema:CreativeWork
    481 https://doi.org/10.18632/oncotarget.16104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084373221
    482 rdf:type schema:CreativeWork
    483 https://doi.org/10.18632/oncotarget.16709 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084373817
    484 rdf:type schema:CreativeWork
    485 https://doi.org/10.18632/oncotarget.18671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090278615
    486 https://app.dimensions.ai/details/publication/pub.1092090480
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.18632/oncotarget.21830 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092231237
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.18632/oncotarget.4057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037067376
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.18632/oncotarget.5759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019641849
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.18632/oncotarget.8589 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011130290
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.18632/oncotarget.9170 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014985992
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.2147/ott.s131597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084757463
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.3389/fimmu.2018.00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100554902
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.3390/ijms18030597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084435893
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.3748/wjg.v21.i41.11680 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071373126
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.3892/or.2013.2304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071532295
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.3892/or.2016.4971 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071534674
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.4137/bbi.s28991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049612043
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.7150/jca.14663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002067362
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.7150/jca.17510 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084002493
    515 rdf:type schema:CreativeWork
    516 https://www.grid.ac/institutes/grid.216417.7 schema:alternateName Central South University
    517 schema:name Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China
    518 The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China
    519 The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China
    520 rdf:type schema:Organization
    521 https://www.grid.ac/institutes/grid.239578.2 schema:alternateName Cleveland Clinic
    522 schema:name Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA
    523 The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Basic Medical Science School and Cancer Research Institute, Central South University, Changsha, Hunan, China
    524 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...