Emerging vancomycin-non susceptible coagulase negative Staphylococci associated with skin and soft tissue infections View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-07-01

AUTHORS

Paul A. Akinduti, Yemisi Dorcas Obafemi, Harriet Ugboko, Maged El-Ashker, Olayemi Akinnola, Chioma Jane Agunsoye, Abiola Oladotun, Bruno S. J. Phiri, Solomon U. Oranusi

ABSTRACT

BackgroundsObservable emergence of Vancomycin-Non susceptible Coagulase-negative Staphylococci (VNS-CoNS) associated with skin and soft tissue infections spreading among the urban and rural populace is gradually intensifying severe complications. The isolated VNS-CoNS were evaluated with Matrix-assisted Laser Desorption/ionization Time of Flight Mass Spectrometry (MALDI ToF MS) for species characterization and pan-antimicrobial resistance pattern.MethodsOut of 256 clinical samples collected including pus, abscess, ear swabs, eye swabs, and aspirates, 91 CoNS isolates were biotyped and further characterized with MALDI-TOF MS. Staphylococci marker genes, Vancomycin susceptibility, and biofilm assays were performed.ResultsOf 91 CoNS isolates, S.cohnii (2.3%), S.condimentii (3.4%), S. saprophyticus (6.7%), and S.scuri (21.1%) were characterized with MALDI-TOF with significant detection rate (99.4%; CI 95, 0.775–0.997, positive predictive values, 90.2%) compared to lower biotyping detection rate (p = 0.001). Hemolytic VNS-CoNS lacked nuc, pvl and spa genes from wound, ear, and aspirates of more 0.83 MARI clustered into a separate phylo-diverse group and were widely distributed in urban and peri-urban locations. MALDI TOF–MS yielded a high discriminatory potential of AUC-ROC score of 0.963 with true-positivity prediction. VNS-CoNS of MIC ≥ 16 µg/mL were observed among all the ages with significant resistance at 25th and 75th quartiles. More than 10.5% of CoNS expressed multi-antibiotic resistance with more than 8 µg/mL vancomycin cut-off values (p < 0.05).ConclusionAntibiotic resistant CoNS should be considered significant pathogens rather than contaminant. Biofilm producing VNS-S. sciuri and S. condimentii are potential strains with high pathological tropism for skin, soft tissues and wound infections, and these strains require urgent surveillance in peri-urban and rural communities. More... »

PAGES

31

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12941-022-00516-4

DOI

http://dx.doi.org/10.1186/s12941-022-00516-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1149161647

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35778767


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coagulase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Resistance, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Soft Tissue Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Staphylococcal Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Staphylococcus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Vancomycin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.411932.c", 
          "name": [
            "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akinduti", 
        "givenName": "Paul A.", 
        "id": "sg:person.01333163744.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333163744.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.411932.c", 
          "name": [
            "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Obafemi", 
        "givenName": "Yemisi Dorcas", 
        "id": "sg:person.011050175357.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011050175357.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.411932.c", 
          "name": [
            "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ugboko", 
        "givenName": "Harriet", 
        "id": "sg:person.015613300030.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015613300030.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, 35516, Mansoura, Egypt", 
          "id": "http://www.grid.ac/institutes/grid.10251.37", 
          "name": [
            "Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, 35516, Mansoura, Egypt"
          ], 
          "type": "Organization"
        }, 
        "familyName": "El-Ashker", 
        "givenName": "Maged", 
        "id": "sg:person.0761765010.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761765010.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.411932.c", 
          "name": [
            "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akinnola", 
        "givenName": "Olayemi", 
        "id": "sg:person.016116503661.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016116503661.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory Unit, Covenant University Health Centre, Ota, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.411932.c", 
          "name": [
            "Laboratory Unit, Covenant University Health Centre, Ota, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Agunsoye", 
        "givenName": "Chioma Jane", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Microbiology, Federal University of Agriculture, Abeokuta, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.448723.e", 
          "name": [
            "Department of Microbiology, Federal University of Agriculture, Abeokuta, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oladotun", 
        "givenName": "Abiola", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central Veterinary Research Institute (CVRI), Lusaka, Zambia", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Central Veterinary Research Institute (CVRI), Lusaka, Zambia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Phiri", 
        "givenName": "Bruno S. J.", 
        "id": "sg:person.014665233047.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014665233047.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria", 
          "id": "http://www.grid.ac/institutes/grid.411932.c", 
          "name": [
            "Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oranusi", 
        "givenName": "Solomon U.", 
        "id": "sg:person.011027332551.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011027332551.25"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/s13756-018-0397-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106410633", 
          "https://doi.org/10.1186/s13756-018-0397-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11250-020-02424-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1131477394", 
          "https://doi.org/10.1007/s11250-020-02424-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/0-387-32892-0_5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016984495", 
          "https://doi.org/10.1007/0-387-32892-0_5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-019-55430-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1123311055", 
          "https://doi.org/10.1038/s41598-019-55430-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-017-11597-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091589965", 
          "https://doi.org/10.1038/s41598-017-11597-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10482-020-01467-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1130621138", 
          "https://doi.org/10.1007/s10482-020-01467-6"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2022-07-01", 
    "datePublishedReg": "2022-07-01", 
    "description": "BackgroundsObservable emergence of Vancomycin-Non susceptible Coagulase-negative Staphylococci (VNS-CoNS) associated with skin and soft tissue infections spreading among the urban and rural populace is gradually intensifying severe complications. The isolated VNS-CoNS were evaluated with Matrix-assisted Laser Desorption/ionization Time of Flight Mass Spectrometry (MALDI ToF MS) for species characterization and pan-antimicrobial resistance pattern.MethodsOut of 256 clinical samples collected including pus, abscess, ear swabs, eye swabs, and aspirates, 91 CoNS isolates were biotyped and further characterized with MALDI-TOF MS. Staphylococci marker genes, Vancomycin susceptibility, and biofilm assays were performed.ResultsOf 91 CoNS isolates,\u00a0S.cohnii\u00a0(2.3%),\u00a0S.condimentii\u00a0(3.4%),\u00a0S. saprophyticus\u00a0(6.7%),\u00a0and S.scuri\u00a0(21.1%) were characterized with MALDI-TOF with significant detection rate (99.4%; CI 95, 0.775\u20130.997, positive predictive values, 90.2%) compared to lower biotyping detection rate (p\u2009=\u20090.001). Hemolytic VNS-CoNS lacked\u00a0nuc, pvl\u00a0and\u00a0spa\u00a0genes from wound, ear, and aspirates of more 0.83 MARI clustered into a separate phylo-diverse group and were widely distributed in urban and peri-urban locations. MALDI TOF\u2013MS yielded a high discriminatory potential of AUC-ROC score of 0.963 with true-positivity prediction. VNS-CoNS of MIC\u2009\u2265\u200916\u00a0\u00b5g/mL were observed among all the ages with significant resistance at 25th and 75th quartiles. More than 10.5% of CoNS expressed multi-antibiotic resistance with more than 8\u00a0\u00b5g/mL vancomycin cut-off values (p\u2009<\u20090.05).ConclusionAntibiotic resistant CoNS should be considered significant pathogens rather than contaminant. Biofilm producing VNS-S. sciuri\u00a0and\u00a0S. condimentii\u00a0are potential strains with high pathological tropism for skin, soft tissues and wound infections, and these strains require urgent surveillance in peri-urban and rural communities.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12941-022-00516-4", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1031269", 
        "issn": [
          "1476-0711"
        ], 
        "name": "Annals of Clinical Microbiology and Antimicrobials", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "21"
      }
    ], 
    "keywords": [
      "soft tissue infections", 
      "coagulase-negative staphylococci", 
      "susceptible coagulase-negative staphylococci", 
      "tissue infections", 
      "CoNS isolates", 
      "multi-antibiotic resistance", 
      "severe complications", 
      "ear swabs", 
      "wound infection", 
      "eye swabs", 
      "detection rate", 
      "resistance patterns", 
      "negative staphylococci", 
      "vancomycin susceptibility", 
      "infection", 
      "soft tissue", 
      "clinical samples", 
      "S. saprophyticus", 
      "significant pathogen", 
      "significant detection rate", 
      "aspirates", 
      "skin", 
      "swabs", 
      "staphylococci", 
      "urgent surveillance", 
      "high discriminatory potential", 
      "significant resistance", 
      "biofilm assays", 
      "MALDI-TOF MS", 
      "MethodsOut", 
      "discriminatory potential", 
      "complications", 
      "isolates", 
      "quartile", 
      "rural communities", 
      "PVL", 
      "flight mass spectrometry", 
      "tropism", 
      "wounds", 
      "age", 
      "MIC", 
      "laser desorption/ionization time", 
      "desorption/ionization time", 
      "ear", 
      "scores", 
      "surveillance", 
      "marker genes", 
      "tissue", 
      "genes", 
      "saprophyticus", 
      "AUC-ROC score", 
      "rural populace", 
      "rate", 
      "peri", 
      "assays", 
      "cons", 
      "resistance", 
      "group", 
      "mL", 
      "pathogens", 
      "strains", 
      "susceptibility", 
      "SpA", 
      "VNS", 
      "TOF-MS", 
      "peri-urban locations", 
      "sciuri", 
      "ionization time", 
      "nuc", 
      "MALDI-TOF", 
      "mass spectrometry", 
      "PU", 
      "cohnii", 
      "potential strain", 
      "patterns", 
      "MS", 
      "samples", 
      "biofilms", 
      "time", 
      "potential", 
      "cut", 
      "emergence", 
      "populace", 
      "location", 
      "values", 
      "spectrometry", 
      "community", 
      "characterization", 
      "species characterization", 
      "prediction", 
      "Mari", 
      "matrix"
    ], 
    "name": "Emerging vancomycin-non susceptible coagulase negative Staphylococci associated with skin and soft tissue infections", 
    "pagination": "31", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1149161647"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12941-022-00516-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "35778767"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12941-022-00516-4", 
      "https://app.dimensions.ai/details/publication/pub.1149161647"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:45", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_955.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12941-022-00516-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12941-022-00516-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12941-022-00516-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12941-022-00516-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12941-022-00516-4'


 

This table displays all metadata directly associated to this object as RDF triples.

269 TRIPLES      21 PREDICATES      130 URIs      116 LITERALS      14 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12941-022-00516-4 schema:about N4624073c2a8f41ebbbcf134753911615
2 N5bc8df3ca8214ff4a75a0d5a953d27e1
3 N87482d2ad7414522ac00743ec831277f
4 Nb183e9ed562a4c3a86f554bf773bc41f
5 Nd69791de6d014db3912ea1e66c5002fe
6 Nde2b2ac2f93a44c4a42afebb59b13aa4
7 Nfd362560b45b468aa2b60b89ba3c94cb
8 anzsrc-for:11
9 anzsrc-for:1103
10 schema:author Na06781445a8044e08365382f3d6b2665
11 schema:citation sg:pub.10.1007/0-387-32892-0_5
12 sg:pub.10.1007/s10482-020-01467-6
13 sg:pub.10.1007/s11250-020-02424-1
14 sg:pub.10.1038/s41598-017-11597-z
15 sg:pub.10.1038/s41598-019-55430-1
16 sg:pub.10.1186/s13756-018-0397-y
17 schema:datePublished 2022-07-01
18 schema:datePublishedReg 2022-07-01
19 schema:description BackgroundsObservable emergence of Vancomycin-Non susceptible Coagulase-negative Staphylococci (VNS-CoNS) associated with skin and soft tissue infections spreading among the urban and rural populace is gradually intensifying severe complications. The isolated VNS-CoNS were evaluated with Matrix-assisted Laser Desorption/ionization Time of Flight Mass Spectrometry (MALDI ToF MS) for species characterization and pan-antimicrobial resistance pattern.MethodsOut of 256 clinical samples collected including pus, abscess, ear swabs, eye swabs, and aspirates, 91 CoNS isolates were biotyped and further characterized with MALDI-TOF MS. Staphylococci marker genes, Vancomycin susceptibility, and biofilm assays were performed.ResultsOf 91 CoNS isolates, S.cohnii (2.3%), S.condimentii (3.4%), S. saprophyticus (6.7%), and S.scuri (21.1%) were characterized with MALDI-TOF with significant detection rate (99.4%; CI 95, 0.775–0.997, positive predictive values, 90.2%) compared to lower biotyping detection rate (p = 0.001). Hemolytic VNS-CoNS lacked nuc, pvl and spa genes from wound, ear, and aspirates of more 0.83 MARI clustered into a separate phylo-diverse group and were widely distributed in urban and peri-urban locations. MALDI TOF–MS yielded a high discriminatory potential of AUC-ROC score of 0.963 with true-positivity prediction. VNS-CoNS of MIC ≥ 16 µg/mL were observed among all the ages with significant resistance at 25th and 75th quartiles. More than 10.5% of CoNS expressed multi-antibiotic resistance with more than 8 µg/mL vancomycin cut-off values (p < 0.05).ConclusionAntibiotic resistant CoNS should be considered significant pathogens rather than contaminant. Biofilm producing VNS-S. sciuri and S. condimentii are potential strains with high pathological tropism for skin, soft tissues and wound infections, and these strains require urgent surveillance in peri-urban and rural communities.
20 schema:genre article
21 schema:isAccessibleForFree true
22 schema:isPartOf N075c8263331d4a7c9fbd166045a972a1
23 N9e0e90ef2eb5447898840a549a1424ea
24 sg:journal.1031269
25 schema:keywords AUC-ROC score
26 CoNS isolates
27 MALDI-TOF
28 MALDI-TOF MS
29 MIC
30 MS
31 Mari
32 MethodsOut
33 PU
34 PVL
35 S. saprophyticus
36 SpA
37 TOF-MS
38 VNS
39 age
40 aspirates
41 assays
42 biofilm assays
43 biofilms
44 characterization
45 clinical samples
46 coagulase-negative staphylococci
47 cohnii
48 community
49 complications
50 cons
51 cut
52 desorption/ionization time
53 detection rate
54 discriminatory potential
55 ear
56 ear swabs
57 emergence
58 eye swabs
59 flight mass spectrometry
60 genes
61 group
62 high discriminatory potential
63 infection
64 ionization time
65 isolates
66 laser desorption/ionization time
67 location
68 mL
69 marker genes
70 mass spectrometry
71 matrix
72 multi-antibiotic resistance
73 negative staphylococci
74 nuc
75 pathogens
76 patterns
77 peri
78 peri-urban locations
79 populace
80 potential
81 potential strain
82 prediction
83 quartile
84 rate
85 resistance
86 resistance patterns
87 rural communities
88 rural populace
89 samples
90 saprophyticus
91 sciuri
92 scores
93 severe complications
94 significant detection rate
95 significant pathogen
96 significant resistance
97 skin
98 soft tissue
99 soft tissue infections
100 species characterization
101 spectrometry
102 staphylococci
103 strains
104 surveillance
105 susceptibility
106 susceptible coagulase-negative staphylococci
107 swabs
108 time
109 tissue
110 tissue infections
111 tropism
112 urgent surveillance
113 values
114 vancomycin susceptibility
115 wound infection
116 wounds
117 schema:name Emerging vancomycin-non susceptible coagulase negative Staphylococci associated with skin and soft tissue infections
118 schema:pagination 31
119 schema:productId N7154e300eb50485795d8f71f23a76148
120 Nabd40932f27b45eca4ec48c68528f248
121 Ndbffaea308c74527ba3c6d3716ac34bf
122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1149161647
123 https://doi.org/10.1186/s12941-022-00516-4
124 schema:sdDatePublished 2022-12-01T06:45
125 schema:sdLicense https://scigraph.springernature.com/explorer/license/
126 schema:sdPublisher N6f4c927e901b47819d493b2422cf0fc5
127 schema:url https://doi.org/10.1186/s12941-022-00516-4
128 sgo:license sg:explorer/license/
129 sgo:sdDataset articles
130 rdf:type schema:ScholarlyArticle
131 N075c8263331d4a7c9fbd166045a972a1 schema:issueNumber 1
132 rdf:type schema:PublicationIssue
133 N0781dfacc92f4ae1a780b131bd1fd027 rdf:first sg:person.014665233047.20
134 rdf:rest N74987d3124d74cd4aa741be014c1be25
135 N1922e451a173472c82ad5595b33aa93a rdf:first N1c396b0a0da143d69d7693552fde1c1d
136 rdf:rest N0781dfacc92f4ae1a780b131bd1fd027
137 N1c396b0a0da143d69d7693552fde1c1d schema:affiliation grid-institutes:grid.448723.e
138 schema:familyName Oladotun
139 schema:givenName Abiola
140 rdf:type schema:Person
141 N4624073c2a8f41ebbbcf134753911615 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Humans
143 rdf:type schema:DefinedTerm
144 N4bc9ab4ded2944219e8460ef43b5ae84 rdf:first sg:person.015613300030.12
145 rdf:rest Ne86cfe19445648fcaea8266ab6237f19
146 N554f3eb1ad254064b2a79876729ac470 schema:affiliation grid-institutes:grid.411932.c
147 schema:familyName Agunsoye
148 schema:givenName Chioma Jane
149 rdf:type schema:Person
150 N5bc8df3ca8214ff4a75a0d5a953d27e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Drug Resistance, Bacterial
152 rdf:type schema:DefinedTerm
153 N6f4c927e901b47819d493b2422cf0fc5 schema:name Springer Nature - SN SciGraph project
154 rdf:type schema:Organization
155 N7154e300eb50485795d8f71f23a76148 schema:name dimensions_id
156 schema:value pub.1149161647
157 rdf:type schema:PropertyValue
158 N74987d3124d74cd4aa741be014c1be25 rdf:first sg:person.011027332551.25
159 rdf:rest rdf:nil
160 N87482d2ad7414522ac00743ec831277f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Coagulase
162 rdf:type schema:DefinedTerm
163 N9be120c2b40547479df21e8ec633a293 rdf:first sg:person.016116503661.36
164 rdf:rest Neab3fe92cc7a464ca9557175ffde4241
165 N9e0e90ef2eb5447898840a549a1424ea schema:volumeNumber 21
166 rdf:type schema:PublicationVolume
167 Na06781445a8044e08365382f3d6b2665 rdf:first sg:person.01333163744.06
168 rdf:rest Ne907620697694a85a89d5f5ca715caca
169 Nabd40932f27b45eca4ec48c68528f248 schema:name pubmed_id
170 schema:value 35778767
171 rdf:type schema:PropertyValue
172 Nb183e9ed562a4c3a86f554bf773bc41f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Staphylococcal Infections
174 rdf:type schema:DefinedTerm
175 Nd69791de6d014db3912ea1e66c5002fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Staphylococcus
177 rdf:type schema:DefinedTerm
178 Ndbffaea308c74527ba3c6d3716ac34bf schema:name doi
179 schema:value 10.1186/s12941-022-00516-4
180 rdf:type schema:PropertyValue
181 Nde2b2ac2f93a44c4a42afebb59b13aa4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Vancomycin
183 rdf:type schema:DefinedTerm
184 Ne86cfe19445648fcaea8266ab6237f19 rdf:first sg:person.0761765010.39
185 rdf:rest N9be120c2b40547479df21e8ec633a293
186 Ne907620697694a85a89d5f5ca715caca rdf:first sg:person.011050175357.63
187 rdf:rest N4bc9ab4ded2944219e8460ef43b5ae84
188 Neab3fe92cc7a464ca9557175ffde4241 rdf:first N554f3eb1ad254064b2a79876729ac470
189 rdf:rest N1922e451a173472c82ad5595b33aa93a
190 Nfd362560b45b468aa2b60b89ba3c94cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Soft Tissue Infections
192 rdf:type schema:DefinedTerm
193 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
194 schema:name Medical and Health Sciences
195 rdf:type schema:DefinedTerm
196 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
197 schema:name Clinical Sciences
198 rdf:type schema:DefinedTerm
199 sg:journal.1031269 schema:issn 1476-0711
200 schema:name Annals of Clinical Microbiology and Antimicrobials
201 schema:publisher Springer Nature
202 rdf:type schema:Periodical
203 sg:person.011027332551.25 schema:affiliation grid-institutes:grid.411932.c
204 schema:familyName Oranusi
205 schema:givenName Solomon U.
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011027332551.25
207 rdf:type schema:Person
208 sg:person.011050175357.63 schema:affiliation grid-institutes:grid.411932.c
209 schema:familyName Obafemi
210 schema:givenName Yemisi Dorcas
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011050175357.63
212 rdf:type schema:Person
213 sg:person.01333163744.06 schema:affiliation grid-institutes:grid.411932.c
214 schema:familyName Akinduti
215 schema:givenName Paul A.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333163744.06
217 rdf:type schema:Person
218 sg:person.014665233047.20 schema:affiliation grid-institutes:None
219 schema:familyName Phiri
220 schema:givenName Bruno S. J.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014665233047.20
222 rdf:type schema:Person
223 sg:person.015613300030.12 schema:affiliation grid-institutes:grid.411932.c
224 schema:familyName Ugboko
225 schema:givenName Harriet
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015613300030.12
227 rdf:type schema:Person
228 sg:person.016116503661.36 schema:affiliation grid-institutes:grid.411932.c
229 schema:familyName Akinnola
230 schema:givenName Olayemi
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016116503661.36
232 rdf:type schema:Person
233 sg:person.0761765010.39 schema:affiliation grid-institutes:grid.10251.37
234 schema:familyName El-Ashker
235 schema:givenName Maged
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761765010.39
237 rdf:type schema:Person
238 sg:pub.10.1007/0-387-32892-0_5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016984495
239 https://doi.org/10.1007/0-387-32892-0_5
240 rdf:type schema:CreativeWork
241 sg:pub.10.1007/s10482-020-01467-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1130621138
242 https://doi.org/10.1007/s10482-020-01467-6
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/s11250-020-02424-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1131477394
245 https://doi.org/10.1007/s11250-020-02424-1
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/s41598-017-11597-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1091589965
248 https://doi.org/10.1038/s41598-017-11597-z
249 rdf:type schema:CreativeWork
250 sg:pub.10.1038/s41598-019-55430-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1123311055
251 https://doi.org/10.1038/s41598-019-55430-1
252 rdf:type schema:CreativeWork
253 sg:pub.10.1186/s13756-018-0397-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1106410633
254 https://doi.org/10.1186/s13756-018-0397-y
255 rdf:type schema:CreativeWork
256 grid-institutes:None schema:alternateName Central Veterinary Research Institute (CVRI), Lusaka, Zambia
257 schema:name Central Veterinary Research Institute (CVRI), Lusaka, Zambia
258 rdf:type schema:Organization
259 grid-institutes:grid.10251.37 schema:alternateName Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, 35516, Mansoura, Egypt
260 schema:name Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, 35516, Mansoura, Egypt
261 rdf:type schema:Organization
262 grid-institutes:grid.411932.c schema:alternateName Laboratory Unit, Covenant University Health Centre, Ota, Nigeria
263 Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria
264 schema:name Laboratory Unit, Covenant University Health Centre, Ota, Nigeria
265 Microbiology Unit, Department of Biological Sciences, Covenant University, Km 10, Idi-Iroko Road, Ota, Nigeria
266 rdf:type schema:Organization
267 grid-institutes:grid.448723.e schema:alternateName Department of Microbiology, Federal University of Agriculture, Abeokuta, Nigeria
268 schema:name Department of Microbiology, Federal University of Agriculture, Abeokuta, Nigeria
269 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...