JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Age Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Contraceptives, Oral, Combined", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Environmental Pollutants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Maternal Exposure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sweden", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time-to-Pregnancy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Unit of Toxicology Sciences, Swetox, Karolinska Institute, S\u00f6dert\u00e4lje, Sweden", 
          "id": "http://www.grid.ac/institutes/grid.4714.6", 
          "name": [
            "Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden", 
            "Unit of Toxicology Sciences, Swetox, Karolinska Institute, S\u00f6dert\u00e4lje, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bj\u00f6rvang", 
        "givenName": "Richelle D.", 
        "id": "sg:person.010711667300.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010711667300.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, USA", 
          "id": "http://www.grid.ac/institutes/grid.59734.3c", 
          "name": [
            "Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gennings", 
        "givenName": "Chris", 
        "id": "sg:person.01107202430.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107202430.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Health Sciences, Karlstad University, Karlstad, Sweden", 
          "id": "http://www.grid.ac/institutes/grid.20258.3d", 
          "name": [
            "Department of Health Sciences, Karlstad University, Karlstad, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Ping-I", 
        "id": "sg:person.01023537571.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023537571.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Obstetrics and Gynecology, Karlstad Central Hospital, Karlstad, Sweden", 
          "id": "http://www.grid.ac/institutes/grid.413655.0", 
          "name": [
            "Department of Obstetrics and Gynecology, Karlstad Central Hospital, Karlstad, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hussein", 
        "givenName": "Ghada", 
        "id": "sg:person.014475151700.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014475151700.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Health Security, National Institute for Health and Welfare, Kuopio, Finland", 
          "id": "http://www.grid.ac/institutes/grid.14758.3f", 
          "name": [
            "Department of Health Security, National Institute for Health and Welfare, Kuopio, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kiviranta", 
        "givenName": "Hannu", 
        "id": "sg:person.01371130433.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371130433.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Health Security, National Institute for Health and Welfare, Kuopio, Finland", 
          "id": "http://www.grid.ac/institutes/grid.14758.3f", 
          "name": [
            "Department of Health Security, National Institute for Health and Welfare, Kuopio, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rantakokko", 
        "givenName": "Panu", 
        "id": "sg:person.01170675055.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170675055.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Health Security, National Institute for Health and Welfare, Kuopio, Finland", 
          "id": "http://www.grid.ac/institutes/grid.14758.3f", 
          "name": [
            "Department of Health Security, National Institute for Health and Welfare, Kuopio, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ruokoj\u00e4rvi", 
        "givenName": "P\u00e4ivi", 
        "id": "sg:person.0577714373.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577714373.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund, Sweden", 
          "id": "http://www.grid.ac/institutes/grid.4514.4", 
          "name": [
            "Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lindh", 
        "givenName": "Christian H.", 
        "id": "sg:person.01127230743.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127230743.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Unit of Toxicology Sciences, Swetox, Karolinska Institute, S\u00f6dert\u00e4lje, Sweden", 
          "id": "http://www.grid.ac/institutes/grid.4714.6", 
          "name": [
            "Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden", 
            "Unit of Toxicology Sciences, Swetox, Karolinska Institute, S\u00f6dert\u00e4lje, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Damdimopoulou", 
        "givenName": "Pauliina", 
        "id": "sg:person.0756777245.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756777245.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Health Sciences, Karlstad University, Karlstad, Sweden", 
          "id": "http://www.grid.ac/institutes/grid.20258.3d", 
          "name": [
            "Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, USA", 
            "Department of Health Sciences, Karlstad University, Karlstad, Sweden"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bornehag", 
        "givenName": "Carl-Gustaf", 
        "id": "sg:person.01165577026.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165577026.11"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1476-069x-12-66", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042234286", 
          "https://doi.org/10.1186/1476-069x-12-66"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-0-387-98141-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041188628", 
          "https://doi.org/10.1007/978-0-387-98141-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12978-016-0224-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046116869", 
          "https://doi.org/10.1186/s12978-016-0224-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13253-014-0180-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028264951", 
          "https://doi.org/10.1007/s13253-014-0180-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/s41598-019-41134-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1113159768", 
          "https://doi.org/10.1038/s41598-019-41134-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00244-001-0048-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002240446", 
          "https://doi.org/10.1007/s00244-001-0048-8"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-06-15", 
    "datePublishedReg": "2020-06-15", 
    "description": "BackgroundWe are exposed to several chemicals such as persistent organic pollutants (POPs) in our everyday lives. Prior evidence has suggested that POPs may have adverse effects on reproductive function by disrupting hormone synthesis and metabolism. While there is age-related decline of fertility, the use of hormonal combined oral contraceptives (COCs) and its association to return of fertility remains controversial. The goal of this study is to investigate the association between exposure to POPs, both individually and as a mixture, and fecundability measured as time-to-pregnancy (TTP) according to pre-pregnancy use of COCs and age.MethodsUsing the SELMA (Swedish Environmental Longitudinal Mother and Child, Allergy and Asthma) study, we have identified 818 pregnant women aged 18\u201343\u2009years (mean 29\u2009years) with data on how long they tried to get pregnant and what was their most recently used contraceptive method. These data were collected at enrollment to the study (median week 10 of pregnancy). Concentrations of 22 POPs and cotinine were analyzed in the blood samples collected at the same time as the questions on TTP and pre-pregnancy use of contraceptive. Analyses were done on the association between POPs exposure and TTP measured as continuous (months) and binary (infertile for those with TTP\u2009>\u200912\u2009months). To study the chemicals individually, Cox regression and logistic regression were used to estimate fecundability ratios (FRs) and odds ratios (ORs), respectively. Weighted quantile sum (WQS) regression was used to investigate the chemicals as a mixture where chemicals of concern were identified above the 7.6% threshold of equal weights. To perform the subgroup analysis, we stratified the sample according to use of COCs as the most recent pre-pregnancy contraception method and age (<\u200929\u2009years, and\u2009\u2265\u200929\u2009years). The models were adjusted for parity, regularity of menses, maternal body mass index (BMI) and smoking status, and stratified as described above.ResultsPrior to stratification, none of the POPs were associated with fecundability while increased exposure to HCB, PCB 74 and 118 had higher odds of infertility. Upon stratification, POP exposure was significantly associated with longer TTP in women aged \u226529\u2009years who did not use COC. Specifically, PCBs 156, 180, 183, and 187 were associated with reduced fecundability while PCBs 99, 153, 156, 180, 183, and 187 had higher odds of infertility. As a mixture, we identified the chemicals of concern for a longer TTP include PCBs 118, 156, 183, and 187. Moreover, chemicals of concern identified with increased odds of infertility were PCB 74, 156, 183, 187, and transnonachlor.ConclusionSerum concentrations of selected POPs, both as individual chemicals and as a mixture, were significantly associated with lower fecundability and increased odds of infertility in women aged 29\u2009years and above not using COC as their most recent pre-pregnancy contraceptive. Our findings suggest that pre-pregnancy use of oral contraceptive and age may modify the link between POPs and fecundability. The differences of specific chemicals in the individual analysis and as a mixture support the need to study combination effects of chemicals when evaluating reproductive outcomes.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12940-020-00608-8", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1327425", 
        "issn": [
          "1476-069X"
        ], 
        "name": "Environmental Health", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "keywords": [
      "pre-pregnancy use", 
      "odds of infertility", 
      "body mass index", 
      "oral contraceptives", 
      "fecundability ratios", 
      "longer TTP", 
      "higher odds", 
      "maternal body mass index", 
      "regularity of menses", 
      "combined oral contraceptives", 
      "POP exposure", 
      "quantile sum (WQS) regression", 
      "use of contraceptives", 
      "ConclusionSerum concentrations", 
      "reduced fecundability", 
      "age-related decline", 
      "mass index", 
      "smoking status", 
      "pregnant women", 
      "Cox regression", 
      "subgroup analysis", 
      "SELMA study", 
      "lower fecundability", 
      "contraception methods", 
      "reproductive outcomes", 
      "contraceptive methods", 
      "blood samples", 
      "PCB 74", 
      "contraceptives", 
      "reproductive function", 
      "infertility", 
      "logistic regression", 
      "fecundability", 
      "adverse effects", 
      "odds", 
      "TTP", 
      "hormone synthesis", 
      "women", 
      "age", 
      "pregnancy", 
      "chemicals of concern", 
      "exposure", 
      "association", 
      "PCB 156", 
      "PCB 118", 
      "prior evidence", 
      "combination effect", 
      "regression", 
      "years", 
      "menses", 
      "individual chemicals", 
      "BackgroundWe", 
      "cotinine", 
      "stratification", 
      "cohort", 
      "persistent organic pollutants", 
      "PCB 99", 
      "individual analysis", 
      "study", 
      "outcomes", 
      "enrollment", 
      "fertility", 
      "metabolism", 
      "use", 
      "status", 
      "transnonachlor", 
      "specific chemicals", 
      "effect", 
      "concern", 
      "concentration", 
      "findings", 
      "parity", 
      "evidence", 
      "index", 
      "samples", 
      "time", 
      "data", 
      "differences", 
      "decline", 
      "weight", 
      "analysis", 
      "life", 
      "ratio", 
      "need", 
      "threshold", 
      "function", 
      "chemicals", 
      "HCB", 
      "method", 
      "goal", 
      "same time", 
      "questions", 
      "link", 
      "everyday life", 
      "equal weight", 
      "model", 
      "synthesis", 
      "pollutants", 
      "mixture", 
      "organic pollutants", 
      "regularity", 
      "binaries"
    ], 
    "name": "Persistent organic pollutants, pre-pregnancy use of combined oral contraceptives, age, and time-to-pregnancy in the SELMA cohort", 
    "pagination": "67", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1128490471"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12940-020-00608-8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "32539770"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12940-020-00608-8", 
      "https://app.dimensions.ai/details/publication/pub.1128490471"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:37", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_847.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12940-020-00608-8"
  }
]

Download the RDF metadata as:  json-ld nt turtle xml License info

This table displays all metadata directly associated to this object as RDF triples.

315 TRIPLES      22 PREDICATES      146 URIs      131 LITERALS      18 BLANK NODES