Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-12

AUTHORS

Ángel Mérida-Ortega, Stephen J. Rothenberg, Luisa Torres-Sánchez, Lourdes Schnaas, César Hernández-Alcaraz, Mariano E. Cebrián, Rosa María García-Hernández, Rafael Ogaz-González, Lizbeth López-Carrillo

ABSTRACT

BACKGROUND: Child neurodevelopment has been positively linked to maternal intake of polyunsaturated fatty acids (PUFAs) during pregnancy; however, it is unknown if that relationship persists among populations exposed to environmental neurotoxicants. OBJECTIVE: The aim of this work was to assess whether maternal dietary intake of PUFAs during pregnancy is positively associated with child neurodevelopment, whose mothers were environmentally exposed to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT). METHODS: A prospective cohort study with 276 mother-child pairs was performed in Mexico. Neurodevelopment was assessed by Bayley Scales II from children age 1 to 30 months. Dietary PUFAs intake was estimated by Food Frequency Questionnaire at 1st and 3rd trimester of pregnancy. DDE (1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene, the main metabolite of DDT) maternal serum levels were determined by electron capture gas chromatography. Longitudinal multivariate linear mixed-effects analysis, which combines mental (MDI) and motor (PDI) Bayley scales in a single model, were performed. RESULTS: Our results show that in a sample environmentally exposed to DDT, maternal ingestion of DPA during the first trimester of pregnancy was positively associated with MDI (β = 0.10, 95% CI 0.02, 0.18) in children from 1 to 30 months. Likewise, our results suggest that dietary ALA may be also related to MDI. CONCLUSION: DPA may benefit neurodevelopment even in populations exposed to DDT. Our results strengthen the importance of PUFAs intake during the prenatal period. More... »

PAGES

17

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12940-019-0456-8

DOI

http://dx.doi.org/10.1186/s12940-019-0456-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112465633

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30819201


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child Development", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DDT", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diet", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Environmental Pollutants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fatty Acids, Unsaturated", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infant, Newborn", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insecticides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Maternal Exposure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Maternal-Fetal Exchange", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mexico", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mothers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Salud P\u00fablica", 
          "id": "https://www.grid.ac/institutes/grid.415771.1", 
          "name": [
            "Centro de Investigaci\u00f3n en Salud Poblacional, Instituto Nacional de Salud P\u00fablica, Av. Universidad 655, Col. Sta. Mar\u00eda Ahuacatitl\u00e1n, 62100, Cuernavaca Morelos, CP, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "M\u00e9rida-Ortega", 
        "givenName": "\u00c1ngel", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Salud P\u00fablica", 
          "id": "https://www.grid.ac/institutes/grid.415771.1", 
          "name": [
            "Centro de Investigaci\u00f3n en Salud Poblacional, Instituto Nacional de Salud P\u00fablica, Av. Universidad 655, Col. Sta. Mar\u00eda Ahuacatitl\u00e1n, 62100, Cuernavaca Morelos, CP, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rothenberg", 
        "givenName": "Stephen J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Salud P\u00fablica", 
          "id": "https://www.grid.ac/institutes/grid.415771.1", 
          "name": [
            "Centro de Investigaci\u00f3n en Salud Poblacional, Instituto Nacional de Salud P\u00fablica, Av. Universidad 655, Col. Sta. Mar\u00eda Ahuacatitl\u00e1n, 62100, Cuernavaca Morelos, CP, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Torres-S\u00e1nchez", 
        "givenName": "Luisa", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Perinatolog\u00eda", 
          "id": "https://www.grid.ac/institutes/grid.419218.7", 
          "name": [
            "Subdirecci\u00f3n de Investigaci\u00f3n en Intervenciones Comunitarias, Instituto Nacional de Perinatolog\u00eda Isidro Espinosa de los Reyes, Ciudad de M\u00e9xico, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schnaas", 
        "givenName": "Lourdes", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Salud P\u00fablica", 
          "id": "https://www.grid.ac/institutes/grid.415771.1", 
          "name": [
            "Centro de Investigaci\u00f3n en Salud Poblacional, Instituto Nacional de Salud P\u00fablica, Av. Universidad 655, Col. Sta. Mar\u00eda Ahuacatitl\u00e1n, 62100, Cuernavaca Morelos, CP, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hern\u00e1ndez-Alcaraz", 
        "givenName": "C\u00e9sar", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Polit\u00e9cnico Nacional", 
          "id": "https://www.grid.ac/institutes/grid.418275.d", 
          "name": [
            "Departamento de Toxicolog\u00eda, Centro de Investigaci\u00f3n y de Estudios Avanzados del IPN, Ciudad de M\u00e9xico, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cebri\u00e1n", 
        "givenName": "Mariano E.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Polit\u00e9cnico Nacional", 
          "id": "https://www.grid.ac/institutes/grid.418275.d", 
          "name": [
            "Departamento de Toxicolog\u00eda, Centro de Investigaci\u00f3n y de Estudios Avanzados del IPN, Ciudad de M\u00e9xico, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Garc\u00eda-Hern\u00e1ndez", 
        "givenName": "Rosa Mar\u00eda", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Salud P\u00fablica", 
          "id": "https://www.grid.ac/institutes/grid.415771.1", 
          "name": [
            "Centro de Investigaci\u00f3n en Salud Poblacional, Instituto Nacional de Salud P\u00fablica, Av. Universidad 655, Col. Sta. Mar\u00eda Ahuacatitl\u00e1n, 62100, Cuernavaca Morelos, CP, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ogaz-Gonz\u00e1lez", 
        "givenName": "Rafael", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Nacional de Salud P\u00fablica", 
          "id": "https://www.grid.ac/institutes/grid.415771.1", 
          "name": [
            "Centro de Investigaci\u00f3n en Salud Poblacional, Instituto Nacional de Salud P\u00fablica, Av. Universidad 655, Col. Sta. Mar\u00eda Ahuacatitl\u00e1n, 62100, Cuernavaca Morelos, CP, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00f3pez-Carrillo", 
        "givenName": "Lizbeth", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1158/1055-9965.epi-07-0394", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001033024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.plipres.2010.07.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003933340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuro.2009.08.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005418136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1753-4887.2011.00381.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017822856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3945/jn.112.163493", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018974219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1289/ehp.9566", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021784209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1475-357x.2003.00073.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022288824"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000448271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030925018"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0007114512001493", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034220341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/pr.2015.50", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035761241", 
          "https://doi.org/10.1038/pr.2015.50"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1289/ehp.7672", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036623694"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuro.2008.06.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037608100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/07315724.2004.10719371", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040825995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1037/a0035628", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042073718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1078/1438-4639-00235", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051298103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10408690590956378", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051436327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/10408690590956378", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051436327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3945/ajcn.112.045781", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051774199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.chc.2014.02.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052618813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.111.1.e39", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053419546"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1289/ehp.00108s3511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064737182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.110.1.110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067821588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s0036-36341998000200005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068098116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/09298673113209990140", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069163323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/3454543", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070328848"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5546/aap.2016.eng.472", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072972392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/65.4.1220s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083068856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12937-017-0242-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084939335", 
          "https://doi.org/10.1186/s12937-017-0242-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12937-017-0242-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084939335", 
          "https://doi.org/10.1186/s12937-017-0242-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(17)32345-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092292439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envpol.2018.03.100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101892578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.envpol.2018.03.100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101892578"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: Child neurodevelopment has been positively linked to maternal intake of polyunsaturated fatty acids (PUFAs) during pregnancy; however, it is unknown if that relationship persists among populations exposed to environmental neurotoxicants.\nOBJECTIVE: The aim of this work was to assess whether maternal dietary intake of PUFAs during pregnancy is positively associated with child neurodevelopment, whose mothers were environmentally exposed to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).\nMETHODS: A prospective cohort study with 276 mother-child pairs was performed in Mexico. Neurodevelopment was assessed by Bayley Scales II from children age 1 to 30\u2009months. Dietary PUFAs intake was estimated by Food Frequency Questionnaire at 1st and 3rd trimester of pregnancy. DDE (1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene, the main metabolite of DDT) maternal serum levels were determined by electron capture gas chromatography. Longitudinal multivariate linear mixed-effects analysis, which combines mental (MDI) and motor (PDI) Bayley scales in a single model, were performed.\nRESULTS: Our results show that in a sample environmentally exposed to DDT, maternal ingestion of DPA during the first trimester of pregnancy was positively associated with MDI (\u03b2\u2009=\u20090.10, 95% CI 0.02, 0.18) in children from 1 to 30\u2009months. Likewise, our results suggest that dietary ALA may be also related to MDI.\nCONCLUSION: DPA may benefit neurodevelopment even in populations exposed to DDT. Our results strengthen the importance of PUFAs intake during the prenatal period.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12940-019-0456-8", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1327425", 
        "issn": [
          "1476-069X"
        ], 
        "name": "Environmental Health", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "name": "Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study", 
    "pagination": "17", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f8158f99007f33c1a248b7ca53daed8effe5c6e2af412bb1cde21ccce1ee4f92"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30819201"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101147645"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12940-019-0456-8"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112465633"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12940-019-0456-8", 
      "https://app.dimensions.ai/details/publication/pub.1112465633"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000367_0000000367/records_88257_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12940-019-0456-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12940-019-0456-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12940-019-0456-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12940-019-0456-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12940-019-0456-8'


 

This table displays all metadata directly associated to this object as RDF triples.

278 TRIPLES      21 PREDICATES      75 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12940-019-0456-8 schema:about N1148f152dccb4022ba6c315d5445db5c
2 N1a79d8042f1245d0a77cc97d01401f86
3 N28f1c5663bb54e23a7bb2e3ced3e7cc4
4 N4766cf930d474128a11b0e2a381b5c1d
5 N5882402eb08848839a251de94b8c5d2d
6 N5da131b73cac44c49254c9fce6032249
7 N6c219fee2b4f42ebbcb0a5fc73ee2e94
8 N6ddc8f57b2a84e34b21b4d44005d8b4e
9 N769ea377516a4ef2b1f4d6da1a7d197f
10 N7ad1c9a00559481d9c401f8c10e4cfc2
11 N94e0d18c55284a1f9c965fd8d908920a
12 Nafa5e7774de5460aa796dcc8ffa8fb7a
13 Nc811ae484cac4ec6b5257b7d90d0d44c
14 Ncc254d633621411fbdd44d2428678607
15 Nd0efd056efa84befa58567f735665087
16 Ndea26a1bd36540888505efa210425562
17 Nf86a29981c1c49119179e6bdb85515b5
18 anzsrc-for:11
19 anzsrc-for:1117
20 schema:author N67bef3847b9d4b27816647334b06f222
21 schema:citation sg:pub.10.1038/pr.2015.50
22 sg:pub.10.1186/s12937-017-0242-9
23 https://doi.org/10.1016/j.chc.2014.02.002
24 https://doi.org/10.1016/j.envpol.2018.03.100
25 https://doi.org/10.1016/j.neuro.2008.06.002
26 https://doi.org/10.1016/j.neuro.2009.08.010
27 https://doi.org/10.1016/j.plipres.2010.07.004
28 https://doi.org/10.1016/s0140-6736(17)32345-0
29 https://doi.org/10.1017/s0007114512001493
30 https://doi.org/10.1037/a0035628
31 https://doi.org/10.1046/j.1475-357x.2003.00073.x
32 https://doi.org/10.1078/1438-4639-00235
33 https://doi.org/10.1080/07315724.2004.10719371
34 https://doi.org/10.1080/10408690590956378
35 https://doi.org/10.1093/ajcn/65.4.1220s
36 https://doi.org/10.1111/j.1753-4887.2011.00381.x
37 https://doi.org/10.1158/1055-9965.epi-07-0394
38 https://doi.org/10.1159/000448271
39 https://doi.org/10.1289/ehp.00108s3511
40 https://doi.org/10.1289/ehp.7672
41 https://doi.org/10.1289/ehp.9566
42 https://doi.org/10.1542/peds.110.1.110
43 https://doi.org/10.1542/peds.111.1.e39
44 https://doi.org/10.1590/s0036-36341998000200005
45 https://doi.org/10.2174/09298673113209990140
46 https://doi.org/10.2307/3454543
47 https://doi.org/10.3945/ajcn.112.045781
48 https://doi.org/10.3945/jn.112.163493
49 https://doi.org/10.5546/aap.2016.eng.472
50 schema:datePublished 2019-12
51 schema:datePublishedReg 2019-12-01
52 schema:description BACKGROUND: Child neurodevelopment has been positively linked to maternal intake of polyunsaturated fatty acids (PUFAs) during pregnancy; however, it is unknown if that relationship persists among populations exposed to environmental neurotoxicants. OBJECTIVE: The aim of this work was to assess whether maternal dietary intake of PUFAs during pregnancy is positively associated with child neurodevelopment, whose mothers were environmentally exposed to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT). METHODS: A prospective cohort study with 276 mother-child pairs was performed in Mexico. Neurodevelopment was assessed by Bayley Scales II from children age 1 to 30 months. Dietary PUFAs intake was estimated by Food Frequency Questionnaire at 1st and 3rd trimester of pregnancy. DDE (1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene, the main metabolite of DDT) maternal serum levels were determined by electron capture gas chromatography. Longitudinal multivariate linear mixed-effects analysis, which combines mental (MDI) and motor (PDI) Bayley scales in a single model, were performed. RESULTS: Our results show that in a sample environmentally exposed to DDT, maternal ingestion of DPA during the first trimester of pregnancy was positively associated with MDI (β = 0.10, 95% CI 0.02, 0.18) in children from 1 to 30 months. Likewise, our results suggest that dietary ALA may be also related to MDI. CONCLUSION: DPA may benefit neurodevelopment even in populations exposed to DDT. Our results strengthen the importance of PUFAs intake during the prenatal period.
53 schema:genre research_article
54 schema:inLanguage en
55 schema:isAccessibleForFree false
56 schema:isPartOf N5e865173478e41359e9241c22c497869
57 N9520ab35560342feb3e933af378173d8
58 sg:journal.1327425
59 schema:name Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study
60 schema:pagination 17
61 schema:productId N251b9b694cb94b68905406761dfd4d02
62 N595345e17f9c4c9aaa5f615ae4a37436
63 Nc23bac040f1544c297b76d6eafd0f447
64 Ncbe0ce2a977a4a8485bf25aa589dae77
65 Nef38240933294e8983398801df415d59
66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112465633
67 https://doi.org/10.1186/s12940-019-0456-8
68 schema:sdDatePublished 2019-04-11T13:12
69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
70 schema:sdPublisher N773044f60f8f4eeb99199982f4a9923c
71 schema:url https://link.springer.com/10.1186%2Fs12940-019-0456-8
72 sgo:license sg:explorer/license/
73 sgo:sdDataset articles
74 rdf:type schema:ScholarlyArticle
75 N0d2d84d9d637446e8874dee36c68175d schema:affiliation https://www.grid.ac/institutes/grid.415771.1
76 schema:familyName Ogaz-González
77 schema:givenName Rafael
78 rdf:type schema:Person
79 N1148f152dccb4022ba6c315d5445db5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Maternal-Fetal Exchange
81 rdf:type schema:DefinedTerm
82 N1a79d8042f1245d0a77cc97d01401f86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Maternal Exposure
84 rdf:type schema:DefinedTerm
85 N251b9b694cb94b68905406761dfd4d02 schema:name dimensions_id
86 schema:value pub.1112465633
87 rdf:type schema:PropertyValue
88 N28f1c5663bb54e23a7bb2e3ced3e7cc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Infant, Newborn
90 rdf:type schema:DefinedTerm
91 N29349efd59db45a6a3b602bc1296c571 schema:affiliation https://www.grid.ac/institutes/grid.419218.7
92 schema:familyName Schnaas
93 schema:givenName Lourdes
94 rdf:type schema:Person
95 N2f61855a52374aeead4a83f5cef78e5a schema:affiliation https://www.grid.ac/institutes/grid.415771.1
96 schema:familyName Hernández-Alcaraz
97 schema:givenName César
98 rdf:type schema:Person
99 N3893f0cd74174c749428a8c6e1761bdd schema:affiliation https://www.grid.ac/institutes/grid.415771.1
100 schema:familyName Rothenberg
101 schema:givenName Stephen J.
102 rdf:type schema:Person
103 N42132e431a7745cc88db6a5ae630dbea rdf:first N734b13461ead451c8aabde03127afe54
104 rdf:rest Ndb91df2d55dc4bbdb8036e7409bf7450
105 N450fc2d1778a413681cd9843a8095214 rdf:first N2f61855a52374aeead4a83f5cef78e5a
106 rdf:rest N539e900808a44eb5a1b10f4a71352026
107 N4766cf930d474128a11b0e2a381b5c1d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Female
109 rdf:type schema:DefinedTerm
110 N539e900808a44eb5a1b10f4a71352026 rdf:first Ncff66394d42a49ec8ab37d8d78c75dde
111 rdf:rest N8001c952d4b7400e8d47d63e1711d836
112 N5882402eb08848839a251de94b8c5d2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Humans
114 rdf:type schema:DefinedTerm
115 N595345e17f9c4c9aaa5f615ae4a37436 schema:name pubmed_id
116 schema:value 30819201
117 rdf:type schema:PropertyValue
118 N5da131b73cac44c49254c9fce6032249 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Fatty Acids, Unsaturated
120 rdf:type schema:DefinedTerm
121 N5e865173478e41359e9241c22c497869 schema:issueNumber 1
122 rdf:type schema:PublicationIssue
123 N5f78624be5e649eda1af82afc913eac5 schema:affiliation https://www.grid.ac/institutes/grid.415771.1
124 schema:familyName López-Carrillo
125 schema:givenName Lizbeth
126 rdf:type schema:Person
127 N5fabaad229164e4e8b76ffd3193c6e3b rdf:first N0d2d84d9d637446e8874dee36c68175d
128 rdf:rest Na95caa6c22294f4bbb335e26f92c5f0b
129 N67bef3847b9d4b27816647334b06f222 rdf:first N9a4ee41ea8dc46b4897aca45dd37f77e
130 rdf:rest N850e0739d41845018c4e16bb35ec3c26
131 N6c219fee2b4f42ebbcb0a5fc73ee2e94 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Mothers
133 rdf:type schema:DefinedTerm
134 N6ddc8f57b2a84e34b21b4d44005d8b4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Diet
136 rdf:type schema:DefinedTerm
137 N719655fac4684152a738b55cf500613a schema:affiliation https://www.grid.ac/institutes/grid.418275.d
138 schema:familyName García-Hernández
139 schema:givenName Rosa María
140 rdf:type schema:Person
141 N734b13461ead451c8aabde03127afe54 schema:affiliation https://www.grid.ac/institutes/grid.415771.1
142 schema:familyName Torres-Sánchez
143 schema:givenName Luisa
144 rdf:type schema:Person
145 N769ea377516a4ef2b1f4d6da1a7d197f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Pregnancy
147 rdf:type schema:DefinedTerm
148 N773044f60f8f4eeb99199982f4a9923c schema:name Springer Nature - SN SciGraph project
149 rdf:type schema:Organization
150 N7ad1c9a00559481d9c401f8c10e4cfc2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Cohort Studies
152 rdf:type schema:DefinedTerm
153 N8001c952d4b7400e8d47d63e1711d836 rdf:first N719655fac4684152a738b55cf500613a
154 rdf:rest N5fabaad229164e4e8b76ffd3193c6e3b
155 N850e0739d41845018c4e16bb35ec3c26 rdf:first N3893f0cd74174c749428a8c6e1761bdd
156 rdf:rest N42132e431a7745cc88db6a5ae630dbea
157 N94e0d18c55284a1f9c965fd8d908920a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Mexico
159 rdf:type schema:DefinedTerm
160 N9520ab35560342feb3e933af378173d8 schema:volumeNumber 18
161 rdf:type schema:PublicationVolume
162 N9a4ee41ea8dc46b4897aca45dd37f77e schema:affiliation https://www.grid.ac/institutes/grid.415771.1
163 schema:familyName Mérida-Ortega
164 schema:givenName Ángel
165 rdf:type schema:Person
166 Na95caa6c22294f4bbb335e26f92c5f0b rdf:first N5f78624be5e649eda1af82afc913eac5
167 rdf:rest rdf:nil
168 Nafa5e7774de5460aa796dcc8ffa8fb7a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name DDT
170 rdf:type schema:DefinedTerm
171 Nc23bac040f1544c297b76d6eafd0f447 schema:name doi
172 schema:value 10.1186/s12940-019-0456-8
173 rdf:type schema:PropertyValue
174 Nc811ae484cac4ec6b5257b7d90d0d44c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Environmental Pollutants
176 rdf:type schema:DefinedTerm
177 Ncbe0ce2a977a4a8485bf25aa589dae77 schema:name nlm_unique_id
178 schema:value 101147645
179 rdf:type schema:PropertyValue
180 Ncc254d633621411fbdd44d2428678607 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Child, Preschool
182 rdf:type schema:DefinedTerm
183 Ncff66394d42a49ec8ab37d8d78c75dde schema:affiliation https://www.grid.ac/institutes/grid.418275.d
184 schema:familyName Cebrián
185 schema:givenName Mariano E.
186 rdf:type schema:Person
187 Nd0efd056efa84befa58567f735665087 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Child Development
189 rdf:type schema:DefinedTerm
190 Ndb91df2d55dc4bbdb8036e7409bf7450 rdf:first N29349efd59db45a6a3b602bc1296c571
191 rdf:rest N450fc2d1778a413681cd9843a8095214
192 Ndea26a1bd36540888505efa210425562 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Insecticides
194 rdf:type schema:DefinedTerm
195 Nef38240933294e8983398801df415d59 schema:name readcube_id
196 schema:value f8158f99007f33c1a248b7ca53daed8effe5c6e2af412bb1cde21ccce1ee4f92
197 rdf:type schema:PropertyValue
198 Nf86a29981c1c49119179e6bdb85515b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Infant
200 rdf:type schema:DefinedTerm
201 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
202 schema:name Medical and Health Sciences
203 rdf:type schema:DefinedTerm
204 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
205 schema:name Public Health and Health Services
206 rdf:type schema:DefinedTerm
207 sg:journal.1327425 schema:issn 1476-069X
208 schema:name Environmental Health
209 rdf:type schema:Periodical
210 sg:pub.10.1038/pr.2015.50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035761241
211 https://doi.org/10.1038/pr.2015.50
212 rdf:type schema:CreativeWork
213 sg:pub.10.1186/s12937-017-0242-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084939335
214 https://doi.org/10.1186/s12937-017-0242-9
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/j.chc.2014.02.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052618813
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/j.envpol.2018.03.100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101892578
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/j.neuro.2008.06.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037608100
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/j.neuro.2009.08.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005418136
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/j.plipres.2010.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003933340
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/s0140-6736(17)32345-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092292439
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1017/s0007114512001493 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034220341
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1037/a0035628 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042073718
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1046/j.1475-357x.2003.00073.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022288824
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1078/1438-4639-00235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051298103
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1080/07315724.2004.10719371 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040825995
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1080/10408690590956378 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051436327
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1093/ajcn/65.4.1220s schema:sameAs https://app.dimensions.ai/details/publication/pub.1083068856
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1111/j.1753-4887.2011.00381.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017822856
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1158/1055-9965.epi-07-0394 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001033024
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1159/000448271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030925018
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1289/ehp.00108s3511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064737182
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1289/ehp.7672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036623694
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1289/ehp.9566 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021784209
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1542/peds.110.1.110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067821588
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1542/peds.111.1.e39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053419546
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1590/s0036-36341998000200005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068098116
259 rdf:type schema:CreativeWork
260 https://doi.org/10.2174/09298673113209990140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069163323
261 rdf:type schema:CreativeWork
262 https://doi.org/10.2307/3454543 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070328848
263 rdf:type schema:CreativeWork
264 https://doi.org/10.3945/ajcn.112.045781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051774199
265 rdf:type schema:CreativeWork
266 https://doi.org/10.3945/jn.112.163493 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018974219
267 rdf:type schema:CreativeWork
268 https://doi.org/10.5546/aap.2016.eng.472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072972392
269 rdf:type schema:CreativeWork
270 https://www.grid.ac/institutes/grid.415771.1 schema:alternateName Instituto Nacional de Salud Pública
271 schema:name Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Av. Universidad 655, Col. Sta. María Ahuacatitlán, 62100, Cuernavaca Morelos, CP, Mexico
272 rdf:type schema:Organization
273 https://www.grid.ac/institutes/grid.418275.d schema:alternateName Instituto Politécnico Nacional
274 schema:name Departamento de Toxicología, Centro de Investigación y de Estudios Avanzados del IPN, Ciudad de México, Mexico
275 rdf:type schema:Organization
276 https://www.grid.ac/institutes/grid.419218.7 schema:alternateName Instituto Nacional de Perinatología
277 schema:name Subdirección de Investigación en Intervenciones Comunitarias, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Ciudad de México, Mexico
278 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...