Comparison of glucose-6 phosphate dehydrogenase status by fluorescent spot test and rapid diagnostic test in Lao PDR and Cambodia View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Gisela Henriques, Koukeo Phommasone, Rupam Tripura, Thomas J. Peto, Shristi Raut, Coco Snethlage, Im Sambo, Nou Sanann, Chea Nguon, Bipin Adhikari, Tiengkham Pongvongsa, Mallika Imwong, Lorenz von Seidlein, Nicholas P. Day, Nicholas J. White, Arjen M. Dondorp, Paul Newton, Benedikt Ley, Mayfong Mayxay

ABSTRACT

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy worldwide. Primaquine is the only licensed drug that effectively removes Plasmodium vivax hypnozoites from the human host and prevents relapse. While well tolerated by most recipients, primaquine can cause haemolysis in G6PD deficient individuals and is, therefore, underused. Rapid diagnostic tests (RDTs) could permit ascertainment of G6PD status outside of laboratory settings and hence safe treatment in remote areas. The performance of the fluorescent spot test (Trinity, Ireland; FST) and a G6PD RDT (Carestart, USA) against spectrophotometry were assessed. METHODS: Participants were enrolled during cross-sectional surveys in Laos and by purposive sampling in Cambodia. FST and RDT were performed during village surveys and 3 mL of venous blood was collected for subsequent G6PD measurement by spectrophotometry. RESULTS: A total of 757 participants were enrolled in Laos and 505 in Cambodia. FST and RDT performed best at 30% cut-off activity and performed significantly better in Laos than in Cambodia. When defining intermediate results as G6PD deficient, the FST had a sensitivity of 100% (95%CI 90-100) and specificity of 90% (95%CI 87.7-92.2) in Laos and sensitivity of 98% (94.1-99.6) and specificity of 71% (95%CI 66-76) in Cambodia (p < 0.001). The RDT had sensitivity and specificity of 100% (95%CI 90-100) and 99% (95%CI 97-99) in Laos and sensitivity and specificity of 91% (86-96) and 93% (90-95) in Cambodia (p < 0.001). The RDT performed significantly better (all p < 0.05) than the FST when intermediate FST results were defined as G6PD deficient. CONCLUSION: The interpretation of RDT results requires some training but is a good alternative to the FST. Trial registration clinicaltrials.gov; NCT01872702; 06/27/2013; https://clinicaltrials.gov/ct2/show/NCT01872702. More... »

PAGES

243

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12936-018-2390-6

DOI

http://dx.doi.org/10.1186/s12936-018-2390-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105049892

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29929514


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1004", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Biotechnology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/10", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Technology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Imperial College London", 
          "id": "https://www.grid.ac/institutes/grid.7445.2", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Department of Life Science, Imperial College London, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Henriques", 
        "givenName": "Gisela", 
        "id": "sg:person.01115505433.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115505433.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahosot Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416302.2", 
          "name": [
            "Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Phommasone", 
        "givenName": "Koukeo", 
        "id": "sg:person.0736206206.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736206206.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tripura", 
        "givenName": "Rupam", 
        "id": "sg:person.01163511634.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163511634.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Peto", 
        "givenName": "Thomas J.", 
        "id": "sg:person.01046403253.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046403253.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahosot Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416302.2", 
          "name": [
            "Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Raut", 
        "givenName": "Shristi", 
        "id": "sg:person.01155773512.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155773512.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Amsterdam", 
          "id": "https://www.grid.ac/institutes/grid.7177.6", 
          "name": [
            "School of Medicine, Amsterdam University, Amsterdam, The Netherlands"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Snethlage", 
        "givenName": "Coco", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahidol University", 
          "id": "https://www.grid.ac/institutes/grid.10223.32", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sambo", 
        "givenName": "Im", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahidol University", 
          "id": "https://www.grid.ac/institutes/grid.10223.32", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sanann", 
        "givenName": "Nou", 
        "id": "sg:person.0707041421.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707041421.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Cambodia National Malaria Center", 
          "id": "https://www.grid.ac/institutes/grid.452707.3", 
          "name": [
            "National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nguon", 
        "givenName": "Chea", 
        "id": "sg:person.0707431241.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707431241.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahidol University", 
          "id": "https://www.grid.ac/institutes/grid.10223.32", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Adhikari", 
        "givenName": "Bipin", 
        "id": "sg:person.01363753576.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363753576.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Savannakhet Provincial Station of Malariology, Parasitology and Entomology, Savannakhet, Savannakhet Province, Lao PDR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pongvongsa", 
        "givenName": "Tiengkham", 
        "id": "sg:person.0602655404.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602655404.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mahidol University", 
          "id": "https://www.grid.ac/institutes/grid.10223.32", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, 10400, Bangkok, Thailand"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imwong", 
        "givenName": "Mallika", 
        "id": "sg:person.01117054563.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117054563.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "von Seidlein", 
        "givenName": "Lorenz", 
        "id": "sg:person.01370347264.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370347264.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Day", 
        "givenName": "Nicholas P.", 
        "id": "sg:person.013570515662.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013570515662.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "White", 
        "givenName": "Nicholas J.", 
        "id": "sg:person.01332073522.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332073522.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dondorp", 
        "givenName": "Arjen M.", 
        "id": "sg:person.01162317707.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162317707.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Oxford", 
          "id": "https://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Newton", 
        "givenName": "Paul", 
        "id": "sg:person.0625571026.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625571026.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Menzies School of Health Research", 
          "id": "https://www.grid.ac/institutes/grid.271089.5", 
          "name": [
            "Menzies School of Health Research, Darwin, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ley", 
        "givenName": "Benedikt", 
        "id": "sg:person.01115040541.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115040541.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Health Sciences Vientiane", 
          "id": "https://www.grid.ac/institutes/grid.412958.3", 
          "name": [
            "Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR", 
            "Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK", 
            "Faculty of Postgraduate Studies, University of Health Sciences, Vientiane, Lao PDR"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mayxay", 
        "givenName": "Mayfong", 
        "id": "sg:person.01372466377.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372466377.78"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1475-2875-13-418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000054784", 
          "https://doi.org/10.1186/1475-2875-13-418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-12-171", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000787400", 
          "https://doi.org/10.1186/1475-2875-12-171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd004389.pub3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005555156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0116143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006472180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007847860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007847860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007847860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014384088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014384088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014384088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0125796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015863708"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-04-077412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017016897"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-11-418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017392148", 
          "https://doi.org/10.1186/1475-2875-11-418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0268-960x(96)90019-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020059231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-12-112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020631200", 
          "https://doi.org/10.1186/1475-2875-12-112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/dddt.s61443", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022503922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.1001339", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023509008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.14-0100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024920815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bcmd.2012.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025191794"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.1979.tb03774.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027772065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-0-12-397900-1.00002-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029277793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12936-015-0896-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029418936", 
          "https://doi.org/10.1186/s12936-015-0896-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10038-005-0279-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031766000", 
          "https://doi.org/10.1007/s10038-005-0279-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10038-005-0279-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031766000", 
          "https://doi.org/10.1007/s10038-005-0279-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrmicro1570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034068739", 
          "https://doi.org/10.1038/nrmicro1570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrmicro1570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034068739", 
          "https://doi.org/10.1038/nrmicro1570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12687-011-0076-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034811782", 
          "https://doi.org/10.1007/s12687-011-0076-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/bjh.12665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035059748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0148172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035942495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0148172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035942495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0148172", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035942495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1475-2875-12-391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040573899", 
          "https://doi.org/10.1186/1475-2875-12-391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(08)60073-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041111007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pntd.0004457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041664130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-0-12-407826-0.00004-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042166376"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0272989x0002000410", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042651294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0272989x0002000410", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042651294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/190372a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048297848", 
          "https://doi.org/10.1038/190372a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4269/ajtmh.2007.77.79", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077584373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1148/radiology.148.3.6878708", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082007470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.1002224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083721030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.1002224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083721030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/2224-3151.213793", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091435411"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra1708111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100194158"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pntd.0006230", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103466211"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0196716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103876074"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-12", 
    "datePublishedReg": "2018-12-01", 
    "description": "BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy worldwide. Primaquine is the only licensed drug that effectively removes Plasmodium vivax hypnozoites from the human host and prevents relapse. While well tolerated by most recipients, primaquine can cause haemolysis in G6PD deficient individuals and is, therefore, underused. Rapid diagnostic tests (RDTs) could permit ascertainment of G6PD status outside of laboratory settings and hence safe treatment in remote areas. The performance of the fluorescent spot test (Trinity, Ireland; FST) and a G6PD RDT (Carestart, USA) against spectrophotometry were assessed.\nMETHODS: Participants were enrolled during cross-sectional surveys in Laos and by purposive sampling in Cambodia. FST and RDT were performed during village surveys and 3\u00a0mL of venous blood was collected for subsequent G6PD measurement by spectrophotometry.\nRESULTS: A total of 757 participants were enrolled in Laos and 505 in Cambodia. FST and RDT performed best at 30% cut-off activity and performed significantly better in Laos than in Cambodia. When defining intermediate results as G6PD deficient, the FST had a sensitivity of 100% (95%CI 90-100) and specificity of 90% (95%CI 87.7-92.2) in Laos and sensitivity of 98% (94.1-99.6) and specificity of 71% (95%CI 66-76) in Cambodia (p\u2009<\u20090.001). The RDT had sensitivity and specificity of 100% (95%CI 90-100) and 99% (95%CI 97-99) in Laos and sensitivity and specificity of 91% (86-96) and 93% (90-95) in Cambodia (p\u2009<\u20090.001). The RDT performed significantly better (all p\u2009<\u20090.05) than the FST when intermediate FST results were defined as G6PD deficient.\nCONCLUSION: The interpretation of RDT results requires some training but is a good alternative to the FST. Trial registration clinicaltrials.gov; NCT01872702; 06/27/2013; https://clinicaltrials.gov/ct2/show/NCT01872702.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12936-018-2390-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6580974", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3643231", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1030597", 
        "issn": [
          "1475-2875"
        ], 
        "name": "Malaria Journal", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "17"
      }
    ], 
    "name": "Comparison of glucose-6 phosphate dehydrogenase status by fluorescent spot test and rapid diagnostic test in Lao PDR and Cambodia", 
    "pagination": "243", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "d79055e655969e8aebde61c8e0034fcb821c30c2d0a3ba4941c717bc343fdd02"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29929514"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101139802"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12936-018-2390-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1105049892"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12936-018-2390-6", 
      "https://app.dimensions.ai/details/publication/pub.1105049892"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:40", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000571.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12936-018-2390-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12936-018-2390-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12936-018-2390-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12936-018-2390-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12936-018-2390-6'


 

This table displays all metadata directly associated to this object as RDF triples.

343 TRIPLES      21 PREDICATES      65 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12936-018-2390-6 schema:about anzsrc-for:10
2 anzsrc-for:1004
3 schema:author N5ed3272f29784e06ae0f6a820b3f9ee6
4 schema:citation sg:pub.10.1007/s10038-005-0279-z
5 sg:pub.10.1007/s12687-011-0076-7
6 sg:pub.10.1038/190372a0
7 sg:pub.10.1038/nrmicro1570
8 sg:pub.10.1186/1475-2875-11-418
9 sg:pub.10.1186/1475-2875-12-112
10 sg:pub.10.1186/1475-2875-12-171
11 sg:pub.10.1186/1475-2875-12-391
12 sg:pub.10.1186/1475-2875-13-418
13 sg:pub.10.1186/s12936-015-0896-8
14 https://doi.org/10.1002/14651858.cd004389.pub3
15 https://doi.org/10.1016/b978-0-12-397900-1.00002-5
16 https://doi.org/10.1016/b978-0-12-407826-0.00004-7
17 https://doi.org/10.1016/j.bcmd.2012.01.001
18 https://doi.org/10.1016/s0140-6736(08)60073-2
19 https://doi.org/10.1016/s0268-960x(96)90019-3
20 https://doi.org/10.1056/nejmra1708111
21 https://doi.org/10.1111/bjh.12665
22 https://doi.org/10.1111/j.1365-2141.1979.tb03774.x
23 https://doi.org/10.1148/radiology.148.3.6878708
24 https://doi.org/10.1177/0272989x0002000410
25 https://doi.org/10.1182/blood-2007-04-077412
26 https://doi.org/10.1371/journal.pmed.1001339
27 https://doi.org/10.1371/journal.pmed.1002224
28 https://doi.org/10.1371/journal.pntd.0004457
29 https://doi.org/10.1371/journal.pntd.0006230
30 https://doi.org/10.1371/journal.pone.0116143
31 https://doi.org/10.1371/journal.pone.0125796
32 https://doi.org/10.1371/journal.pone.0148172
33 https://doi.org/10.1371/journal.pone.0196716
34 https://doi.org/10.2147/dddt.s61443
35 https://doi.org/10.4103/2224-3151.213793
36 https://doi.org/10.4269/ajtmh.14-0100
37 https://doi.org/10.4269/ajtmh.14-0194
38 https://doi.org/10.4269/ajtmh.14-0696
39 https://doi.org/10.4269/ajtmh.2007.77.79
40 schema:datePublished 2018-12
41 schema:datePublishedReg 2018-12-01
42 schema:description BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy worldwide. Primaquine is the only licensed drug that effectively removes Plasmodium vivax hypnozoites from the human host and prevents relapse. While well tolerated by most recipients, primaquine can cause haemolysis in G6PD deficient individuals and is, therefore, underused. Rapid diagnostic tests (RDTs) could permit ascertainment of G6PD status outside of laboratory settings and hence safe treatment in remote areas. The performance of the fluorescent spot test (Trinity, Ireland; FST) and a G6PD RDT (Carestart, USA) against spectrophotometry were assessed. METHODS: Participants were enrolled during cross-sectional surveys in Laos and by purposive sampling in Cambodia. FST and RDT were performed during village surveys and 3 mL of venous blood was collected for subsequent G6PD measurement by spectrophotometry. RESULTS: A total of 757 participants were enrolled in Laos and 505 in Cambodia. FST and RDT performed best at 30% cut-off activity and performed significantly better in Laos than in Cambodia. When defining intermediate results as G6PD deficient, the FST had a sensitivity of 100% (95%CI 90-100) and specificity of 90% (95%CI 87.7-92.2) in Laos and sensitivity of 98% (94.1-99.6) and specificity of 71% (95%CI 66-76) in Cambodia (p < 0.001). The RDT had sensitivity and specificity of 100% (95%CI 90-100) and 99% (95%CI 97-99) in Laos and sensitivity and specificity of 91% (86-96) and 93% (90-95) in Cambodia (p < 0.001). The RDT performed significantly better (all p < 0.05) than the FST when intermediate FST results were defined as G6PD deficient. CONCLUSION: The interpretation of RDT results requires some training but is a good alternative to the FST. Trial registration clinicaltrials.gov; NCT01872702; 06/27/2013; https://clinicaltrials.gov/ct2/show/NCT01872702.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree true
46 schema:isPartOf N1aca0968da74475f8117483c510c3220
47 Ne422771fbbb7456cb79322d17e284dd5
48 sg:journal.1030597
49 schema:name Comparison of glucose-6 phosphate dehydrogenase status by fluorescent spot test and rapid diagnostic test in Lao PDR and Cambodia
50 schema:pagination 243
51 schema:productId N06ef7685499b439b9c172179803c0086
52 N4abb3cd945bc43f2bb08707278e81386
53 N5018d6696a824edabbb1100e4b15bb97
54 N57c1287d02614b30b6b215e57a4d38e5
55 N75c8836656ae4e9095a7db7939c13037
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105049892
57 https://doi.org/10.1186/s12936-018-2390-6
58 schema:sdDatePublished 2019-04-10T17:40
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher Nb133f7b954704068b992b51562b9ac3e
61 schema:url https://link.springer.com/10.1186%2Fs12936-018-2390-6
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N017269551d564cb89158e66939253b42 rdf:first sg:person.01117054563.36
66 rdf:rest N3c737477734b496db8c846a076500ac7
67 N06ef7685499b439b9c172179803c0086 schema:name pubmed_id
68 schema:value 29929514
69 rdf:type schema:PropertyValue
70 N1aca0968da74475f8117483c510c3220 schema:issueNumber 1
71 rdf:type schema:PublicationIssue
72 N36f5f8c34d024717819b9f69065db547 rdf:first sg:person.01163511634.36
73 rdf:rest N67c6ca57fa0a440992d2af7128206ad6
74 N37b14d53c27344d79c08faedcccb1b66 schema:affiliation https://www.grid.ac/institutes/grid.7177.6
75 schema:familyName Snethlage
76 schema:givenName Coco
77 rdf:type schema:Person
78 N3c737477734b496db8c846a076500ac7 rdf:first sg:person.01370347264.09
79 rdf:rest Nf911b25b37f04e2f8ffa4b414b86af39
80 N4102342e040a4ae28d48ac116d316675 rdf:first sg:person.0707041421.34
81 rdf:rest N9504bb2403994017aafcdb863a2a05f4
82 N4abb3cd945bc43f2bb08707278e81386 schema:name doi
83 schema:value 10.1186/s12936-018-2390-6
84 rdf:type schema:PropertyValue
85 N5018d6696a824edabbb1100e4b15bb97 schema:name dimensions_id
86 schema:value pub.1105049892
87 rdf:type schema:PropertyValue
88 N569c45f5496540c28f2200884635bde1 rdf:first sg:person.01363753576.34
89 rdf:rest Nc3f80a79cb704a50bf184c444659e11b
90 N57c1287d02614b30b6b215e57a4d38e5 schema:name nlm_unique_id
91 schema:value 101139802
92 rdf:type schema:PropertyValue
93 N5ed3272f29784e06ae0f6a820b3f9ee6 rdf:first sg:person.01115505433.22
94 rdf:rest N8707ad5f9864455c9d23124b698d655a
95 N62608f1b13b34f97b701db94c63affce rdf:first Nc9b44b01bd4e438ab63fed116dcdee0a
96 rdf:rest N4102342e040a4ae28d48ac116d316675
97 N67c6ca57fa0a440992d2af7128206ad6 rdf:first sg:person.01046403253.46
98 rdf:rest Nb43ad1033b7e49eea65d1444b03202e2
99 N72ec375a2213412db82c3e13d6346f11 rdf:first sg:person.0625571026.24
100 rdf:rest Nef127794af61490787156fec554c183a
101 N75c8836656ae4e9095a7db7939c13037 schema:name readcube_id
102 schema:value d79055e655969e8aebde61c8e0034fcb821c30c2d0a3ba4941c717bc343fdd02
103 rdf:type schema:PropertyValue
104 N8707ad5f9864455c9d23124b698d655a rdf:first sg:person.0736206206.04
105 rdf:rest N36f5f8c34d024717819b9f69065db547
106 N915443c670d9498c875304d3ee0bae8f rdf:first sg:person.01372466377.78
107 rdf:rest rdf:nil
108 N9504bb2403994017aafcdb863a2a05f4 rdf:first sg:person.0707431241.45
109 rdf:rest N569c45f5496540c28f2200884635bde1
110 Nb133f7b954704068b992b51562b9ac3e schema:name Springer Nature - SN SciGraph project
111 rdf:type schema:Organization
112 Nb43ad1033b7e49eea65d1444b03202e2 rdf:first sg:person.01155773512.43
113 rdf:rest Nd604a1ca212e470186a3b932eda7dda7
114 Nc3f80a79cb704a50bf184c444659e11b rdf:first sg:person.0602655404.64
115 rdf:rest N017269551d564cb89158e66939253b42
116 Nc9b44b01bd4e438ab63fed116dcdee0a schema:affiliation https://www.grid.ac/institutes/grid.10223.32
117 schema:familyName Sambo
118 schema:givenName Im
119 rdf:type schema:Person
120 Nd604a1ca212e470186a3b932eda7dda7 rdf:first N37b14d53c27344d79c08faedcccb1b66
121 rdf:rest N62608f1b13b34f97b701db94c63affce
122 Ne422771fbbb7456cb79322d17e284dd5 schema:volumeNumber 17
123 rdf:type schema:PublicationVolume
124 Ne5a873834111405c838f2fd25d07e190 rdf:first sg:person.01332073522.49
125 rdf:rest Nf2b9670d371f4917aee07b8a4414857d
126 Nef127794af61490787156fec554c183a rdf:first sg:person.01115040541.55
127 rdf:rest N915443c670d9498c875304d3ee0bae8f
128 Nf2b9670d371f4917aee07b8a4414857d rdf:first sg:person.01162317707.88
129 rdf:rest N72ec375a2213412db82c3e13d6346f11
130 Nf6e8800b3e8340a184e7afec3b48caab schema:name Savannakhet Provincial Station of Malariology, Parasitology and Entomology, Savannakhet, Savannakhet Province, Lao PDR
131 rdf:type schema:Organization
132 Nf911b25b37f04e2f8ffa4b414b86af39 rdf:first sg:person.013570515662.78
133 rdf:rest Ne5a873834111405c838f2fd25d07e190
134 anzsrc-for:10 schema:inDefinedTermSet anzsrc-for:
135 schema:name Technology
136 rdf:type schema:DefinedTerm
137 anzsrc-for:1004 schema:inDefinedTermSet anzsrc-for:
138 schema:name Medical Biotechnology
139 rdf:type schema:DefinedTerm
140 sg:grant.3643231 http://pending.schema.org/fundedItem sg:pub.10.1186/s12936-018-2390-6
141 rdf:type schema:MonetaryGrant
142 sg:grant.6580974 http://pending.schema.org/fundedItem sg:pub.10.1186/s12936-018-2390-6
143 rdf:type schema:MonetaryGrant
144 sg:journal.1030597 schema:issn 1475-2875
145 schema:name Malaria Journal
146 rdf:type schema:Periodical
147 sg:person.01046403253.46 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
148 schema:familyName Peto
149 schema:givenName Thomas J.
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046403253.46
151 rdf:type schema:Person
152 sg:person.01115040541.55 schema:affiliation https://www.grid.ac/institutes/grid.271089.5
153 schema:familyName Ley
154 schema:givenName Benedikt
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115040541.55
156 rdf:type schema:Person
157 sg:person.01115505433.22 schema:affiliation https://www.grid.ac/institutes/grid.7445.2
158 schema:familyName Henriques
159 schema:givenName Gisela
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01115505433.22
161 rdf:type schema:Person
162 sg:person.01117054563.36 schema:affiliation https://www.grid.ac/institutes/grid.10223.32
163 schema:familyName Imwong
164 schema:givenName Mallika
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117054563.36
166 rdf:type schema:Person
167 sg:person.01155773512.43 schema:affiliation https://www.grid.ac/institutes/grid.416302.2
168 schema:familyName Raut
169 schema:givenName Shristi
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155773512.43
171 rdf:type schema:Person
172 sg:person.01162317707.88 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
173 schema:familyName Dondorp
174 schema:givenName Arjen M.
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162317707.88
176 rdf:type schema:Person
177 sg:person.01163511634.36 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
178 schema:familyName Tripura
179 schema:givenName Rupam
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163511634.36
181 rdf:type schema:Person
182 sg:person.01332073522.49 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
183 schema:familyName White
184 schema:givenName Nicholas J.
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332073522.49
186 rdf:type schema:Person
187 sg:person.013570515662.78 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
188 schema:familyName Day
189 schema:givenName Nicholas P.
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013570515662.78
191 rdf:type schema:Person
192 sg:person.01363753576.34 schema:affiliation https://www.grid.ac/institutes/grid.10223.32
193 schema:familyName Adhikari
194 schema:givenName Bipin
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363753576.34
196 rdf:type schema:Person
197 sg:person.01370347264.09 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
198 schema:familyName von Seidlein
199 schema:givenName Lorenz
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370347264.09
201 rdf:type schema:Person
202 sg:person.01372466377.78 schema:affiliation https://www.grid.ac/institutes/grid.412958.3
203 schema:familyName Mayxay
204 schema:givenName Mayfong
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372466377.78
206 rdf:type schema:Person
207 sg:person.0602655404.64 schema:affiliation Nf6e8800b3e8340a184e7afec3b48caab
208 schema:familyName Pongvongsa
209 schema:givenName Tiengkham
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602655404.64
211 rdf:type schema:Person
212 sg:person.0625571026.24 schema:affiliation https://www.grid.ac/institutes/grid.4991.5
213 schema:familyName Newton
214 schema:givenName Paul
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625571026.24
216 rdf:type schema:Person
217 sg:person.0707041421.34 schema:affiliation https://www.grid.ac/institutes/grid.10223.32
218 schema:familyName Sanann
219 schema:givenName Nou
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707041421.34
221 rdf:type schema:Person
222 sg:person.0707431241.45 schema:affiliation https://www.grid.ac/institutes/grid.452707.3
223 schema:familyName Nguon
224 schema:givenName Chea
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707431241.45
226 rdf:type schema:Person
227 sg:person.0736206206.04 schema:affiliation https://www.grid.ac/institutes/grid.416302.2
228 schema:familyName Phommasone
229 schema:givenName Koukeo
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736206206.04
231 rdf:type schema:Person
232 sg:pub.10.1007/s10038-005-0279-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1031766000
233 https://doi.org/10.1007/s10038-005-0279-z
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/s12687-011-0076-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034811782
236 https://doi.org/10.1007/s12687-011-0076-7
237 rdf:type schema:CreativeWork
238 sg:pub.10.1038/190372a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048297848
239 https://doi.org/10.1038/190372a0
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/nrmicro1570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034068739
242 https://doi.org/10.1038/nrmicro1570
243 rdf:type schema:CreativeWork
244 sg:pub.10.1186/1475-2875-11-418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017392148
245 https://doi.org/10.1186/1475-2875-11-418
246 rdf:type schema:CreativeWork
247 sg:pub.10.1186/1475-2875-12-112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020631200
248 https://doi.org/10.1186/1475-2875-12-112
249 rdf:type schema:CreativeWork
250 sg:pub.10.1186/1475-2875-12-171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000787400
251 https://doi.org/10.1186/1475-2875-12-171
252 rdf:type schema:CreativeWork
253 sg:pub.10.1186/1475-2875-12-391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040573899
254 https://doi.org/10.1186/1475-2875-12-391
255 rdf:type schema:CreativeWork
256 sg:pub.10.1186/1475-2875-13-418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000054784
257 https://doi.org/10.1186/1475-2875-13-418
258 rdf:type schema:CreativeWork
259 sg:pub.10.1186/s12936-015-0896-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029418936
260 https://doi.org/10.1186/s12936-015-0896-8
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1002/14651858.cd004389.pub3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005555156
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1016/b978-0-12-397900-1.00002-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029277793
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1016/b978-0-12-407826-0.00004-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042166376
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1016/j.bcmd.2012.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025191794
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1016/s0140-6736(08)60073-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041111007
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1016/s0268-960x(96)90019-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020059231
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1056/nejmra1708111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100194158
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1111/bjh.12665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035059748
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1111/j.1365-2141.1979.tb03774.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027772065
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1148/radiology.148.3.6878708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082007470
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1177/0272989x0002000410 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042651294
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1182/blood-2007-04-077412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017016897
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1371/journal.pmed.1001339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023509008
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1371/journal.pmed.1002224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083721030
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1371/journal.pntd.0004457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041664130
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1371/journal.pntd.0006230 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103466211
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1371/journal.pone.0116143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006472180
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1371/journal.pone.0125796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015863708
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1371/journal.pone.0148172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035942495
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1371/journal.pone.0196716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103876074
301 rdf:type schema:CreativeWork
302 https://doi.org/10.2147/dddt.s61443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022503922
303 rdf:type schema:CreativeWork
304 https://doi.org/10.4103/2224-3151.213793 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091435411
305 rdf:type schema:CreativeWork
306 https://doi.org/10.4269/ajtmh.14-0100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024920815
307 rdf:type schema:CreativeWork
308 https://doi.org/10.4269/ajtmh.14-0194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007847860
309 rdf:type schema:CreativeWork
310 https://doi.org/10.4269/ajtmh.14-0696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014384088
311 rdf:type schema:CreativeWork
312 https://doi.org/10.4269/ajtmh.2007.77.79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077584373
313 rdf:type schema:CreativeWork
314 https://www.grid.ac/institutes/grid.10223.32 schema:alternateName Mahidol University
315 schema:name Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, 10400, Bangkok, Thailand
316 Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
317 rdf:type schema:Organization
318 https://www.grid.ac/institutes/grid.271089.5 schema:alternateName Menzies School of Health Research
319 schema:name Menzies School of Health Research, Darwin, Australia
320 rdf:type schema:Organization
321 https://www.grid.ac/institutes/grid.412958.3 schema:alternateName University of Health Sciences Vientiane
322 schema:name Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
323 Faculty of Postgraduate Studies, University of Health Sciences, Vientiane, Lao PDR
324 Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR
325 rdf:type schema:Organization
326 https://www.grid.ac/institutes/grid.416302.2 schema:alternateName Mahosot Hospital
327 schema:name Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR
328 rdf:type schema:Organization
329 https://www.grid.ac/institutes/grid.452707.3 schema:alternateName Cambodia National Malaria Center
330 schema:name National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia
331 rdf:type schema:Organization
332 https://www.grid.ac/institutes/grid.4991.5 schema:alternateName University of Oxford
333 schema:name Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
334 Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Vientiane, Lao PDR
335 Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
336 rdf:type schema:Organization
337 https://www.grid.ac/institutes/grid.7177.6 schema:alternateName University of Amsterdam
338 schema:name School of Medicine, Amsterdam University, Amsterdam, The Netherlands
339 rdf:type schema:Organization
340 https://www.grid.ac/institutes/grid.7445.2 schema:alternateName Imperial College London
341 schema:name Department of Life Science, Imperial College London, London, UK
342 Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
343 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...