Identification and characterization of areas of high and low risk for asymptomatic malaria infections at sub-village level in Ratanakiri, Cambodia View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Lies Durnez, Myrthe Pareyn, Vanna Mean, Saorin Kim, Nimol Khim, Didier Menard, Marc Coosemans, Tho Sochantha, Vincent Sluydts

ABSTRACT

BACKGROUND: Malaria elimination needs a concentration of activities towards identification of residual transmission foci and intensification of efforts to eliminate the last few infections, located in so-called 'malaria hotspots'. Previous work on characterizing malaria transmission hotspots has mainly focused on falciparum malaria and especially on symptomatic cases, while the malaria reservoir is expected to be mainly concentrated in the asymptomatic human population when transmission is low. For Plasmodium vivax, there has been less effort in identifying transmission hotspots. The main aim of this study was to uncover micro-epidemiological mechanisms of clustering of malaria infections at a sub-village level, based on geographical or behavioural features. METHODS: A cross-sectional survey was performed in three villages within the highest malaria endemic province of Cambodia. The survey took place in the dry season, when the malaria reservoir is expected to be low and residing in the asymptomatic part of the population. Village and field locations of households were georeferenced, blood samples were taken from as many residents as possible and a short questionnaire probing for individual risk factors was taken. Asymptomatic malaria carriers were detected by PCR, and geographical clustering analysis (SaTScan) as well as risk factor analysis were performed. RESULTS: A total of 1540 out of 1792 (86%) individuals were sampled. Plasmodial DNA was detected in 129 individuals (8.4%). P. vivax was most prevalent (5.5%) followed by Plasmodium malariae (2.1%) and Plasmodium falciparum (1.6%). Mixed infection occurred in 12 individuals. In two out of three villages geographical clustering of high and low malaria infection risk was clearly present. Cluster location and risk factors associated with the infection differed between the parasite species. Age was an important risk factor for the combined Plasmodium infections, while watching television at evenings was associated with increased odds of P. vivax infections [OR (CI): 1.86 (0.95-3.64)] and bed net use was associated with reduced odds of P. falciparum infections [OR (CI): 0.25 (0.077-0.80)]. CONCLUSIONS: Clusters of malaria carriers were malaria species specific and often located remotely, outside village centres. As such, at micro-epidemiological level, malaria is not a single disease. Further unravelling the micro-epidemiology of malaria can enable programme managers to define the interventions likely to contribute to halt transmission in a particular hotspot location. More... »

PAGES

27

References to SciGraph publications

  • 2012-12. Spatial-temporal analysis of malaria and the effect of environmental factors on its incidence in Yongcheng, China, 2006–2010 in BMC PUBLIC HEALTH
  • 2014-12. Identifying malaria hotspots in Keur Soce health and demographic surveillance site in context of low transmission in MALARIA JOURNAL
  • 2012-01. Factors determining the occurrence of submicroscopic malaria infections and their relevance for control in NATURE COMMUNICATIONS
  • 2013-12. The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial in TRIALS
  • 2005-12. Epidemiology of forest malaria in central Vietnam: a large scale cross-sectional survey in MALARIA JOURNAL
  • 2013-12. Impact of climate variability on Plasmodium vivax and Plasmodium falciparum malaria in Yunnan Province, China in FILARIA JOURNAL
  • 2010-12. Sub-microscopic malaria cases and mixed malaria infection in a remote area of high malaria endemicity in Rattanakiri province, Cambodia: implication for malaria elimination in MALARIA JOURNAL
  • 2010-12. The impact of human reservoir of malaria at a community-level on individual malaria occurrence in a low malaria transmission setting along the Thai-Myanmar border in MALARIA JOURNAL
  • 2013-12-11. Ecology and Control of Vector-borne diseases in NONE
  • 2007-12. The Anopheles dirus complex: spatial distribution and environmental drivers in MALARIA JOURNAL
  • 2015-12. Microgeography and molecular epidemiology of malaria at the Thailand-Myanmar border in the malaria pre-elimination phase in MALARIA JOURNAL
  • 2017-12. Submicroscopic Plasmodium prevalence in relation to malaria incidence in 20 villages in western Cambodia in MALARIA JOURNAL
  • 2010-12. Review of software for space-time disease surveillance in INTERNATIONAL JOURNAL OF HEALTH GEOGRAPHICS
  • 2013-12. Deforestation, agriculture and farm jobs: a good recipe for Plasmodium vivax in French Guiana in MALARIA JOURNAL
  • 2015-12. Re-imagining malaria: heterogeneity of human and mosquito behaviour in relation to residual malaria transmission in Cambodia in MALARIA JOURNAL
  • 2013-12. Outdoor malaria transmission in forested villages of Cambodia in MALARIA JOURNAL
  • 2013-12. Geographic information systems and logistic regression for high-resolution malaria risk mapping in a rural settlement of the southern Brazilian Amazon in MALARIA JOURNAL
  • 2008-12. Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand in MALARIA JOURNAL
  • 2007-12. Large-scale malaria survey in Cambodia: Novel insights on species distribution and risk factors in MALARIA JOURNAL
  • 2014-12. Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia in MALARIA JOURNAL
  • 2013-12. Anopheles species associations in Southeast Asia: indicator species and environmental influences in FILARIA JOURNAL
  • 2006-12. Spatial and temporal variation in malaria transmission in a low endemicity area in northern Tanzania in MALARIA JOURNAL
  • 2014-12. Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections in MALARIA JOURNAL
  • 2013-12. An innovative tool for moving malaria PCR detection of parasite reservoir into the field in MALARIA JOURNAL
  • 2015-12. Plasmodium vivax malaria at households: spatial clustering and risk factors in a low endemicity urban area of the northwestern Peruvian coast in MALARIA JOURNAL
  • 2010-04. Artemisinin resistance: current status and scenarios for containment in NATURE REVIEWS MICROBIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12936-017-2169-1

    DOI

    http://dx.doi.org/10.1186/s12936-017-2169-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1100404583

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29334956


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