A reduction in malaria transmission intensity in Northern Ghana after 7 years of indoor residual spraying View Full Text


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Article Info

DATE

2017-08-10

AUTHORS

Sylvester Coleman, Samuel K. Dadzie, Aklilu Seyoum, Yemane Yihdego, Peter Mumba, Dereje Dengela, Philip Ricks, Kristen George, Christen Fornadel, Daniel Szumlas, Paul Psychas, Jacob Williams, Maxwell A. Appawu, Daniel A. Boakye

ABSTRACT

BACKGROUND: Indoor residual spraying (IRS) is being implemented as one of the malaria prevention methods in the Northern Region of Ghana. Changes in longevity, sporozoite and entomological inoculation rates (EIRs) of major malaria vectors were monitored to assess the impact of IRS in selected districts. METHODS: Monthly human landing catches (HLCs) were used to collect mosquitoes from sentinel sites in three adjacent districts between July 2009 and December 2014: Savelugu Nanton (SND) where IRS had been implemented from 2008 to 2014; Tolon Kumbungu (TKD) where IRS had been implemented between 2008 and 2012 and Tamale Metropolis (TML) with no history of IRS. Mosquitoes were morphologically identified to species level and into sibling species, using PCR. Samples of Anopheles gambiae sensu lato (s.l.) were examined for parity and infectivity. EIR was calculated from biting and infectivity rates of malaria vectors. RESULTS: Parity rates of An. gambiae s.l. decreased significantly (p < 0.0001) in SND from 44.8% in 2011 to 28.1% by 2014, and in TKD from 53.3% in 2011 to 46.6% in 2012 (p = 0.001). However 2 years after IRS was discontinued in TKD, the proportion of parous An. gambiae s.l. increased significantly to 68.5% in 2014 (p < 0.0001). Parity rates in the unsprayed district remained high throughout the study period, ranging between 68.6% in 2011 and 72.3% in 2014. The sum of monthly EIRs post-IRS season (July-December) in SND ranged between 2.1 and 6.3 infective bites/person/season (ib/p/s) during the 3 years that the district was sprayed with alphacypermethrin. EIR in SND was reduced to undetectable levels when the insecticide was switched to pirimiphos methyl CS in 2013 and 2014. Two years after IRS was withdrawn from TKD the sum of monthly EIRs (July-December) increased by about fourfold from 41.8 ib/p/s in 2012 to 154.4 ib/p/s in 2014. The EIR in the control area, TML, ranged between 35 ib/p/s in 2009 to 104.71 ib/p/s by 2014. CONCLUSIONS: This study demonstrates that IRS application did have a significant impact on entomological indicators of malaria transmission in the IRS project districts of Northern Ghana. Transmission indicators increased following the withdrawal of IRS from Tolon Kumbungu District. More... »

PAGES

324

References to SciGraph publications

  • 2014-05-30. Good performances but short lasting efficacy of Actellic 50 EC Indoor Residual Spraying (IRS) on malaria transmission in Benin, West Africa in PARASITES & VECTORS
  • 2013-02-07. Successful malaria elimination strategies require interventions that target changing vector behaviours in MALARIA JOURNAL
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  • 2013-02-13. Spatio-temporal malaria transmission patterns in Navrongo demographic surveillance site, northern Ghana in MALARIA JOURNAL
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  • 2012-08-08. Evaluation of the efficacy of bendiocarb in indoor residual spraying against pyrethroid resistant malaria vectors in Benin: results of the third campaign in PARASITES & VECTORS
  • 2012-12-29. Impact assessment of malaria vector control using routine surveillance data in Zambia: implications for monitoring and evaluation in MALARIA JOURNAL
  • 2016-01-22. Strategies towards attainment of universal coverage of long lasting insecticide treated nets (LLINs) distribution: experiences and lessons from Ghana in PARASITES & VECTORS
  • 2015-06-24. Preventing malaria transmission by indoor residual spraying in Malawi: grappling with the challenge of uncertain sustainability in MALARIA JOURNAL
  • 2010-03-03. Community-wide benefits of targeted indoor residual spray for malaria control in the Western Kenya Highland in MALARIA JOURNAL
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    http://scigraph.springernature.com/pub.10.1186/s12936-017-1971-0

    DOI

    http://dx.doi.org/10.1186/s12936-017-1971-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1091143218

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28797269


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