Impact of diabetes in patients waiting for invasive cardiac procedures during COVID-19 pandemic View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-03-23

AUTHORS

Raúl Moreno, José-Luis Díez, José-Antonio Diarte, Pablo Salinas, José María de la Torre Hernández, Juan F. Andres-Cordón, Ramiro Trillo, Juan Alonso Briales, Ignacio Amat-Santos, Rafael Romaguera, José-Francisco Díaz, Beatriz Vaquerizo, Soledad Ojeda, Ignacio Cruz-González, Daniel Morena-Salas, Armando Pérez de Prado, Fernando Sarnago, Pilar Portero, Alejandro Gutierrez-Barrios, Fernando Alfonso, Eduard Bosch, Eduardo Pinar, José-Ramón Ruiz-Arroyo, Valeriano Ruiz-Quevedo, Jesús Jiménez-Mazuecos, Fernando Lozano, José-Ramón Rumoroso, Enrique Novo, Francisco J. Irazusta, Bruno García del Blanco, José Moreu, Sara M. Ballesteros-Pradas, Araceli Frutos, Manuel Villa, Eduardo Alegría-Barrero, Rosa Lázaro, Emilio Paredes

ABSTRACT

BACKGROUND: During COVID-19 pandemic, elective invasive cardiac procedures (ICP) have been frequently cancelled or postponed. Consequences may be more evident in patients with diabetes. OBJECTIVES: The objective was to identify the peculiarities of patients with DM among those in whom ICP were cancelled or postponed due to the COVID-19 pandemic, as well as to identify subgroups in which the influence of DM has higher impact on the clinical outcome. METHODS: We included 2,158 patients in whom an elective ICP was cancelled or postponed during COVID-19 pandemic in 37 hospitals in Spain. Among them, 700 (32.4%) were diabetics. Patients with and without diabetes were compared. RESULTS: Patients with diabetes were older and had a higher prevalence of other cardiovascular risk factors, previous cardiovascular history and co-morbidities. Diabetics had a higher mortality (3.0% vs. 1.0%; p = 0.001) and cardiovascular mortality (1.9% vs. 0.4%; p = 0.001). Differences were especially important in patients with valvular heart disease (mortality 6.9% vs 1.7% [p < 0.001] and cardiovascular mortality 4.9% vs 0.9% [p = 0.002] in patients with and without diabetes, respectively). In the multivariable analysis, diabetes remained as an independent risk factor both for overall and cardiovascular mortality. No significant interaction was found with other clinical variables. CONCLUSION: Among patients in whom an elective invasive cardiac procedure is cancelled or postponed during COVID-19 pandemic, mortality and cardiovascular mortality is higher in patients with diabetes, irrespectively on other clinical conditions. These procedures should not be cancelled in patients with diabetes. More... »

PAGES

69

Journal

TITLE

Cardiovascular Diabetology

ISSUE

1

VOLUME

20

Author Affiliations

  • University Hospital La Paz, idiPAZ, Paseo La Castellana 261, 28046 Madrid, Spain
  • Hospital La Fe, Valencia, Spain
  • Hospital Miguel Servet, Zaragoza, Spain
  • Hospital Clínico San Carlos, Madrid, Spain
  • Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain
  • Hospital German Trias I Pujol, Badalona, Spain
  • Hospital Clínico Universitario, Santiago de Compostela, Spain
  • Hospital Virgen de La Victoria, Málaga, Spain
  • Hospital Clínico Universitario, Valladolid, Spain
  • Hospital de Bellvitge, Barcelona, Spain
  • Hospital Juan Ramón Jiménez, Huelva, Spain
  • Hospital del Mar, Barcelona, Spain
  • Hospital Reina Sofía, Córdoba, Spain
  • Hospital Universitario de Salamanca, IBSAL, CIBER CV, Salamanca, Spain
  • Hospital de Cabueñes, Gijón, Spain
  • Complejo Hospitalario, León, Spain
  • Hospital Doce de Octubre, Madrid, Spain
  • Hospital San Pedro de La Rioja, Logroño, Spain
  • Hospital Puerta del Mar, Cádiz, Spain
  • Hospital de La Princesa, Madrid, Spain
  • Corporació Sanitaria Parc Tauli, Sabadell, Spain
  • Hospital Virgen de L´Arrixaca, Murcia, Spain
  • Hospital Lozano Blesa, Zaragoza, Spain
  • Hospital Clínico de Navarra, Pamplona, Spain
  • Hospital Universitario, Albacete, Spain
  • Hospital General Universitario, Ciudad Real, Spain
  • Hospital de Galdakao, Bilbao, Spain
  • Hospital Universitario, Guadalajara, Spain
  • Policlínica de Guipúzcoa, San Sebastian, Spain
  • Hospital Vall D´Hebron, Barcelona, Spain
  • Hospital Virgen de La Salud, Toledo, Spain
  • Hospital de Valme, Sevilla, Spain
  • Hospital San Juan, Alicante, Spain
  • Hospital Virgen del Rocío, Sevilla, Spain
  • Hospital Ruber Internacional, Madrid, Spain
  • Hospital de Torrecárdenas, Almería, Spain
  • Investiga, Moaña, Pontevedra, Spain
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12933-021-01261-2

    DOI

    http://dx.doi.org/10.1186/s12933-021-01261-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1136612411

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/33757510


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