Impact of stress on oocyte quality and reproductive outcome View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-03-29

AUTHORS

Shilpa Prasad, Meenakshi Tiwari, Ashutosh N. Pandey, Tulsidas G. Shrivastav, Shail K. Chaube

ABSTRACT

Stress is an important factor that affects physical and mental status of a healthy person disturbing homeostasis of the body. Changes in the lifestyle are one of the major causes that lead to psychological stress. Psychological stress could impact the biology of female reproduction by targeting at the level of ovary, follicle and oocyte. The increased level of stress hormone such as cortisol reduces estradiol production possibly by affecting the granulosa cell functions within the follicle, which results deterioration in oocyte quality. Adaptation of lifestyle behaviours may generate reactive oxygen species (ROS) in the ovary, which further affects female reproduction. Balance between level of ROS and antioxidants within the ovary are important for maintenance of female reproductive health. Physiological level of ROS modulates oocyte functions, while its accumulation leads to oxidative stress (OS). OS triggers apoptosis in majority of germ cells within the ovary and even in ovulated oocytes. Although both mitochondria- as well as death-receptor pathways are involved in oocyte apoptosis, OS-induced mitochondria-mediated pathway plays a major role in the elimination of majority of germ cells from ovary. OS in the follicular fluid deteriorates oocyte quality and reduces reproductive outcome. On the other hand, antioxidants reduce ROS levels and protect against OS-mediated germ cell apoptosis and thereby depletion of germ cells from the ovary. Indeed, OS is one of the major factors that has a direct negative impact on oocyte quality and limits female reproductive outcome in several mammalian species including human. More... »

PAGES

36

References to SciGraph publications

  • 2013-07-16. Lifestyle factors and reproductive health: taking control of your fertility in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
  • 2013-05-01. Environmental factors and unhealthy lifestyle influence oxidative stress in humans—an overview in ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
  • 2012-02-07. High cytosolic free calcium level signals apoptosis through mitochondria-caspase mediated pathway in rat eggs cultured in vitro in APOPTOSIS
  • 2015-05-10. Apoptosis in mammalian oocytes: a review in APOPTOSIS
  • 2005-07-14. Role of oxidative stress in female reproduction in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
  • 2001-01. Oxidative stress and the ovary. in REPRODUCTIVE SCIENCES
  • 2011-07-12. Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems in JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
  • 2005-03. Reactive oxygen species in ovarian physiology in REPRODUCTIVE MEDICINE AND BIOLOGY
  • 2005-08. Hydrogen peroxide modulates meiotic cell cycle and induces morphological features characteristic of apoptosis in rat oocytes cultured in vitro in APOPTOSIS
  • 2005-09-02. Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
  • 2012-06-29. The effects of oxidative stress on female reproduction: a review in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
  • 2004-12-03. Role of reactive oxygen species in gynecologic diseases in REPRODUCTIVE MEDICINE AND BIOLOGY
  • 2009-05-04. Follicular fluid content and oocyte quality: from single biochemical markers to metabolomics in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
  • 2014-08-26. Neem (Azadirachta indica L.) leaf extract deteriorates oocyte quality by inducing ROS-mediated apoptosis in mammals in SPRINGERPLUS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12929-016-0253-4

    DOI

    http://dx.doi.org/10.1186/s12929-016-0253-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1048639392

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27026099


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Paediatrics and Reproductive Medicine", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Granulosa Cells", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hydrocortisone", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Oocytes", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Oxidative Stress", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Reactive Oxygen Species", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Reproduction", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Stress, Psychological", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India", 
              "id": "http://www.grid.ac/institutes/grid.411507.6", 
              "name": [
                "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Prasad", 
            "givenName": "Shilpa", 
            "id": "sg:person.0713150174.41", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713150174.41"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India", 
              "id": "http://www.grid.ac/institutes/grid.411507.6", 
              "name": [
                "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tiwari", 
            "givenName": "Meenakshi", 
            "id": "sg:person.0645034774.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645034774.12"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India", 
              "id": "http://www.grid.ac/institutes/grid.411507.6", 
              "name": [
                "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pandey", 
            "givenName": "Ashutosh N.", 
            "id": "sg:person.01305424057.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305424057.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Reproductive Biomedicine, National Institute of Health and Family Welfare, Baba Gang Nath Marg, Munirka, 110067, New Delhi, India", 
              "id": "http://www.grid.ac/institutes/grid.416764.6", 
              "name": [
                "Department of Reproductive Biomedicine, National Institute of Health and Family Welfare, Baba Gang Nath Marg, Munirka, 110067, New Delhi, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shrivastav", 
            "givenName": "Tulsidas G.", 
            "id": "sg:person.0764553223.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764553223.46"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India", 
              "id": "http://www.grid.ac/institutes/grid.411507.6", 
              "name": [
                "Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chaube", 
            "givenName": "Shail K.", 
            "id": "sg:person.01170561413.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170561413.11"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1186/1477-7827-10-49", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022180024", 
              "https://doi.org/10.1186/1477-7827-10-49"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10815-011-9604-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003662046", 
              "https://doi.org/10.1007/s10815-011-9604-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/2193-1801-3-464", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002338437", 
              "https://doi.org/10.1186/2193-1801-3-464"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-7827-3-28", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019926167", 
              "https://doi.org/10.1186/1477-7827-3-28"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10495-015-1136-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035307894", 
              "https://doi.org/10.1007/s10495-015-1136-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf03016135", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023077360", 
              "https://doi.org/10.1007/bf03016135"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-7827-7-40", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028212423", 
              "https://doi.org/10.1186/1477-7827-7-40"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10495-005-0367-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043687306", 
              "https://doi.org/10.1007/s10495-005-0367-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/j.1447-0578.2004.00068.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047463443", 
              "https://doi.org/10.1111/j.1447-0578.2004.00068.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1016/s1071-5576(00)00106-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054678877", 
              "https://doi.org/10.1016/s1071-5576(00)00106-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10495-012-0702-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023539905", 
              "https://doi.org/10.1007/s10495-012-0702-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11356-013-1748-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027739509", 
              "https://doi.org/10.1007/s11356-013-1748-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-7827-3-43", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038867042", 
              "https://doi.org/10.1186/1477-7827-3-43"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1477-7827-11-66", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051198039", 
              "https://doi.org/10.1186/1477-7827-11-66"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2016-03-29", 
        "datePublishedReg": "2016-03-29", 
        "description": "Stress is an important factor that affects physical and mental status of a healthy person disturbing homeostasis of the body. Changes in the lifestyle are one of the major causes that lead to psychological stress. Psychological stress could impact the biology of female reproduction by targeting at the level of ovary, follicle and oocyte. The increased level of stress hormone such as cortisol reduces estradiol production possibly by affecting the granulosa cell functions within the follicle, which results deterioration in oocyte quality. Adaptation of lifestyle behaviours may generate reactive oxygen species (ROS) in the ovary, which further affects female reproduction. Balance between level of ROS and antioxidants within the ovary are important for maintenance of female reproductive health. Physiological level of ROS modulates oocyte functions, while its accumulation leads to oxidative stress (OS). OS triggers apoptosis in majority of germ cells within the ovary and even in ovulated oocytes. Although both mitochondria- as well as death-receptor pathways are involved in oocyte apoptosis, OS-induced mitochondria-mediated pathway plays a major role in the elimination of majority of germ cells from ovary. OS in the follicular fluid deteriorates oocyte quality and reduces reproductive outcome. On the other hand, antioxidants reduce ROS levels and protect against OS-mediated germ cell apoptosis and thereby depletion of germ cells from the ovary. Indeed, OS is one of the major factors that has a direct negative impact on oocyte quality and limits female reproductive outcome in several mammalian species including human.", 
        "genre": "article", 
        "id": "sg:pub.10.1186/s12929-016-0253-4", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.8561772", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1105665", 
            "issn": [
              "1021-7770", 
              "1423-0127"
            ], 
            "name": "Journal of Biomedical Science", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "23"
          }
        ], 
        "keywords": [
          "reactive oxygen species", 
          "reproductive outcomes", 
          "germ cells", 
          "oocyte quality", 
          "oxidative stress", 
          "female reproduction", 
          "psychological stress", 
          "death receptor pathway", 
          "female reproductive health", 
          "granulosa cell function", 
          "female reproductive outcomes", 
          "levels of ROS", 
          "mitochondria-mediated pathway", 
          "germ cell apoptosis", 
          "mammalian species", 
          "estradiol production", 
          "lifestyle behaviors", 
          "mental status", 
          "triggers apoptosis", 
          "healthy persons", 
          "reproductive health", 
          "stress hormones", 
          "oocyte apoptosis", 
          "major cause", 
          "ovulated oocytes", 
          "cell apoptosis", 
          "ROS levels", 
          "cell function", 
          "oxygen species", 
          "apoptosis", 
          "physiological levels", 
          "outcomes", 
          "impact of stress", 
          "follicles", 
          "species", 
          "reproduction", 
          "ovaries", 
          "pathway", 
          "oocytes", 
          "cells", 
          "antioxidants", 
          "major role", 
          "direct negative impact", 
          "levels", 
          "majority", 
          "mitochondria", 
          "stress", 
          "cortisol", 
          "biology", 
          "hormone", 
          "homeostasis", 
          "factors", 
          "modulates", 
          "cause", 
          "health", 
          "lifestyle", 
          "major factor", 
          "status", 
          "important factor", 
          "accumulation", 
          "function", 
          "humans", 
          "adaptation", 
          "quality", 
          "persons", 
          "maintenance", 
          "deterioration", 
          "depletion", 
          "negative impact", 
          "role", 
          "elimination", 
          "production", 
          "impact", 
          "body", 
          "changes", 
          "balance", 
          "hand", 
          "deteriorates", 
          "behavior"
        ], 
        "name": "Impact of stress on oocyte quality and reproductive outcome", 
        "pagination": "36", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1048639392"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s12929-016-0253-4"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "27026099"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s12929-016-0253-4", 
          "https://app.dimensions.ai/details/publication/pub.1048639392"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T16:00", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_692.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1186/s12929-016-0253-4"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12929-016-0253-4'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12929-016-0253-4'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12929-016-0253-4'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12929-016-0253-4'


     

    This table displays all metadata directly associated to this object as RDF triples.

    277 TRIPLES      21 PREDICATES      130 URIs      106 LITERALS      17 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s12929-016-0253-4 schema:about N0bc8e1299d3e46219a4258ff57f93d8a
    2 N0e18feba237646f4b1583588150ae8bd
    3 N2bf07625cf1943f2afe763e5c03a6bdc
    4 N2f4b4055bfda4c9684b93defce0968be
    5 N75d6be6a14e545a09d452a768beb0c84
    6 N8bdcc9b89a984b6db9251b9bc143d6e0
    7 N96bd44256fd64946aa1f240f3557974b
    8 Nb7fc172908754d15aded6c86b6a3b32c
    9 Ncbff5a6152f24db7853f907a2bbedff6
    10 Nfe11158024c748078b66ba555a4fed09
    11 anzsrc-for:06
    12 anzsrc-for:0601
    13 anzsrc-for:11
    14 anzsrc-for:1114
    15 schema:author N55ce3ebe718444749ff448b0da2840f6
    16 schema:citation sg:pub.10.1007/bf03016135
    17 sg:pub.10.1007/s10495-005-0367-8
    18 sg:pub.10.1007/s10495-012-0702-9
    19 sg:pub.10.1007/s10495-015-1136-y
    20 sg:pub.10.1007/s10815-011-9604-y
    21 sg:pub.10.1007/s11356-013-1748-0
    22 sg:pub.10.1016/s1071-5576(00)00106-4
    23 sg:pub.10.1111/j.1447-0578.2004.00068.x
    24 sg:pub.10.1186/1477-7827-10-49
    25 sg:pub.10.1186/1477-7827-11-66
    26 sg:pub.10.1186/1477-7827-3-28
    27 sg:pub.10.1186/1477-7827-3-43
    28 sg:pub.10.1186/1477-7827-7-40
    29 sg:pub.10.1186/2193-1801-3-464
    30 schema:datePublished 2016-03-29
    31 schema:datePublishedReg 2016-03-29
    32 schema:description Stress is an important factor that affects physical and mental status of a healthy person disturbing homeostasis of the body. Changes in the lifestyle are one of the major causes that lead to psychological stress. Psychological stress could impact the biology of female reproduction by targeting at the level of ovary, follicle and oocyte. The increased level of stress hormone such as cortisol reduces estradiol production possibly by affecting the granulosa cell functions within the follicle, which results deterioration in oocyte quality. Adaptation of lifestyle behaviours may generate reactive oxygen species (ROS) in the ovary, which further affects female reproduction. Balance between level of ROS and antioxidants within the ovary are important for maintenance of female reproductive health. Physiological level of ROS modulates oocyte functions, while its accumulation leads to oxidative stress (OS). OS triggers apoptosis in majority of germ cells within the ovary and even in ovulated oocytes. Although both mitochondria- as well as death-receptor pathways are involved in oocyte apoptosis, OS-induced mitochondria-mediated pathway plays a major role in the elimination of majority of germ cells from ovary. OS in the follicular fluid deteriorates oocyte quality and reduces reproductive outcome. On the other hand, antioxidants reduce ROS levels and protect against OS-mediated germ cell apoptosis and thereby depletion of germ cells from the ovary. Indeed, OS is one of the major factors that has a direct negative impact on oocyte quality and limits female reproductive outcome in several mammalian species including human.
    33 schema:genre article
    34 schema:isAccessibleForFree true
    35 schema:isPartOf N3840dd3adafb4562b1008213e4682cf6
    36 N713fd5eabfe540bc93888439ba203266
    37 sg:journal.1105665
    38 schema:keywords ROS levels
    39 accumulation
    40 adaptation
    41 antioxidants
    42 apoptosis
    43 balance
    44 behavior
    45 biology
    46 body
    47 cause
    48 cell apoptosis
    49 cell function
    50 cells
    51 changes
    52 cortisol
    53 death receptor pathway
    54 depletion
    55 deteriorates
    56 deterioration
    57 direct negative impact
    58 elimination
    59 estradiol production
    60 factors
    61 female reproduction
    62 female reproductive health
    63 female reproductive outcomes
    64 follicles
    65 function
    66 germ cell apoptosis
    67 germ cells
    68 granulosa cell function
    69 hand
    70 health
    71 healthy persons
    72 homeostasis
    73 hormone
    74 humans
    75 impact
    76 impact of stress
    77 important factor
    78 levels
    79 levels of ROS
    80 lifestyle
    81 lifestyle behaviors
    82 maintenance
    83 major cause
    84 major factor
    85 major role
    86 majority
    87 mammalian species
    88 mental status
    89 mitochondria
    90 mitochondria-mediated pathway
    91 modulates
    92 negative impact
    93 oocyte apoptosis
    94 oocyte quality
    95 oocytes
    96 outcomes
    97 ovaries
    98 ovulated oocytes
    99 oxidative stress
    100 oxygen species
    101 pathway
    102 persons
    103 physiological levels
    104 production
    105 psychological stress
    106 quality
    107 reactive oxygen species
    108 reproduction
    109 reproductive health
    110 reproductive outcomes
    111 role
    112 species
    113 status
    114 stress
    115 stress hormones
    116 triggers apoptosis
    117 schema:name Impact of stress on oocyte quality and reproductive outcome
    118 schema:pagination 36
    119 schema:productId N20ef7e3b73bd440ea411f503ec9b0a09
    120 Nd941333967044a9a8d065cb24ebeb0f4
    121 Neac4d4fc19924405897aa3070f613e72
    122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048639392
    123 https://doi.org/10.1186/s12929-016-0253-4
    124 schema:sdDatePublished 2022-09-02T16:00
    125 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    126 schema:sdPublisher Nc709d51d58fa44de9df4a7a54a7171fc
    127 schema:url https://doi.org/10.1186/s12929-016-0253-4
    128 sgo:license sg:explorer/license/
    129 sgo:sdDataset articles
    130 rdf:type schema:ScholarlyArticle
    131 N0bc8e1299d3e46219a4258ff57f93d8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    132 schema:name Humans
    133 rdf:type schema:DefinedTerm
    134 N0e18feba237646f4b1583588150ae8bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    135 schema:name Stress, Psychological
    136 rdf:type schema:DefinedTerm
    137 N10093484e84b420888e22421e06a3883 rdf:first sg:person.01170561413.11
    138 rdf:rest rdf:nil
    139 N20ef7e3b73bd440ea411f503ec9b0a09 schema:name pubmed_id
    140 schema:value 27026099
    141 rdf:type schema:PropertyValue
    142 N2bf07625cf1943f2afe763e5c03a6bdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    143 schema:name Oocytes
    144 rdf:type schema:DefinedTerm
    145 N2f4b4055bfda4c9684b93defce0968be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    146 schema:name Reactive Oxygen Species
    147 rdf:type schema:DefinedTerm
    148 N3016002470cf44d295f063082cec745e rdf:first sg:person.01305424057.18
    149 rdf:rest N69fa7fd1e99646d9ba66f1c60138cdd5
    150 N3840dd3adafb4562b1008213e4682cf6 schema:volumeNumber 23
    151 rdf:type schema:PublicationVolume
    152 N55ce3ebe718444749ff448b0da2840f6 rdf:first sg:person.0713150174.41
    153 rdf:rest N93734c7262ba49989ad61bb289a3ff93
    154 N69fa7fd1e99646d9ba66f1c60138cdd5 rdf:first sg:person.0764553223.46
    155 rdf:rest N10093484e84b420888e22421e06a3883
    156 N713fd5eabfe540bc93888439ba203266 schema:issueNumber 1
    157 rdf:type schema:PublicationIssue
    158 N75d6be6a14e545a09d452a768beb0c84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    159 schema:name Reproduction
    160 rdf:type schema:DefinedTerm
    161 N8bdcc9b89a984b6db9251b9bc143d6e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    162 schema:name Female
    163 rdf:type schema:DefinedTerm
    164 N93734c7262ba49989ad61bb289a3ff93 rdf:first sg:person.0645034774.12
    165 rdf:rest N3016002470cf44d295f063082cec745e
    166 N96bd44256fd64946aa1f240f3557974b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    167 schema:name Hydrocortisone
    168 rdf:type schema:DefinedTerm
    169 Nb7fc172908754d15aded6c86b6a3b32c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    170 schema:name Granulosa Cells
    171 rdf:type schema:DefinedTerm
    172 Nc709d51d58fa44de9df4a7a54a7171fc schema:name Springer Nature - SN SciGraph project
    173 rdf:type schema:Organization
    174 Ncbff5a6152f24db7853f907a2bbedff6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    175 schema:name Animals
    176 rdf:type schema:DefinedTerm
    177 Nd941333967044a9a8d065cb24ebeb0f4 schema:name doi
    178 schema:value 10.1186/s12929-016-0253-4
    179 rdf:type schema:PropertyValue
    180 Neac4d4fc19924405897aa3070f613e72 schema:name dimensions_id
    181 schema:value pub.1048639392
    182 rdf:type schema:PropertyValue
    183 Nfe11158024c748078b66ba555a4fed09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    184 schema:name Oxidative Stress
    185 rdf:type schema:DefinedTerm
    186 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    187 schema:name Biological Sciences
    188 rdf:type schema:DefinedTerm
    189 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    190 schema:name Biochemistry and Cell Biology
    191 rdf:type schema:DefinedTerm
    192 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    193 schema:name Medical and Health Sciences
    194 rdf:type schema:DefinedTerm
    195 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
    196 schema:name Paediatrics and Reproductive Medicine
    197 rdf:type schema:DefinedTerm
    198 sg:grant.8561772 http://pending.schema.org/fundedItem sg:pub.10.1186/s12929-016-0253-4
    199 rdf:type schema:MonetaryGrant
    200 sg:journal.1105665 schema:issn 1021-7770
    201 1423-0127
    202 schema:name Journal of Biomedical Science
    203 schema:publisher Springer Nature
    204 rdf:type schema:Periodical
    205 sg:person.01170561413.11 schema:affiliation grid-institutes:grid.411507.6
    206 schema:familyName Chaube
    207 schema:givenName Shail K.
    208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170561413.11
    209 rdf:type schema:Person
    210 sg:person.01305424057.18 schema:affiliation grid-institutes:grid.411507.6
    211 schema:familyName Pandey
    212 schema:givenName Ashutosh N.
    213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305424057.18
    214 rdf:type schema:Person
    215 sg:person.0645034774.12 schema:affiliation grid-institutes:grid.411507.6
    216 schema:familyName Tiwari
    217 schema:givenName Meenakshi
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645034774.12
    219 rdf:type schema:Person
    220 sg:person.0713150174.41 schema:affiliation grid-institutes:grid.411507.6
    221 schema:familyName Prasad
    222 schema:givenName Shilpa
    223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713150174.41
    224 rdf:type schema:Person
    225 sg:person.0764553223.46 schema:affiliation grid-institutes:grid.416764.6
    226 schema:familyName Shrivastav
    227 schema:givenName Tulsidas G.
    228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764553223.46
    229 rdf:type schema:Person
    230 sg:pub.10.1007/bf03016135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023077360
    231 https://doi.org/10.1007/bf03016135
    232 rdf:type schema:CreativeWork
    233 sg:pub.10.1007/s10495-005-0367-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043687306
    234 https://doi.org/10.1007/s10495-005-0367-8
    235 rdf:type schema:CreativeWork
    236 sg:pub.10.1007/s10495-012-0702-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023539905
    237 https://doi.org/10.1007/s10495-012-0702-9
    238 rdf:type schema:CreativeWork
    239 sg:pub.10.1007/s10495-015-1136-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1035307894
    240 https://doi.org/10.1007/s10495-015-1136-y
    241 rdf:type schema:CreativeWork
    242 sg:pub.10.1007/s10815-011-9604-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1003662046
    243 https://doi.org/10.1007/s10815-011-9604-y
    244 rdf:type schema:CreativeWork
    245 sg:pub.10.1007/s11356-013-1748-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027739509
    246 https://doi.org/10.1007/s11356-013-1748-0
    247 rdf:type schema:CreativeWork
    248 sg:pub.10.1016/s1071-5576(00)00106-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054678877
    249 https://doi.org/10.1016/s1071-5576(00)00106-4
    250 rdf:type schema:CreativeWork
    251 sg:pub.10.1111/j.1447-0578.2004.00068.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047463443
    252 https://doi.org/10.1111/j.1447-0578.2004.00068.x
    253 rdf:type schema:CreativeWork
    254 sg:pub.10.1186/1477-7827-10-49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022180024
    255 https://doi.org/10.1186/1477-7827-10-49
    256 rdf:type schema:CreativeWork
    257 sg:pub.10.1186/1477-7827-11-66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051198039
    258 https://doi.org/10.1186/1477-7827-11-66
    259 rdf:type schema:CreativeWork
    260 sg:pub.10.1186/1477-7827-3-28 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019926167
    261 https://doi.org/10.1186/1477-7827-3-28
    262 rdf:type schema:CreativeWork
    263 sg:pub.10.1186/1477-7827-3-43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038867042
    264 https://doi.org/10.1186/1477-7827-3-43
    265 rdf:type schema:CreativeWork
    266 sg:pub.10.1186/1477-7827-7-40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028212423
    267 https://doi.org/10.1186/1477-7827-7-40
    268 rdf:type schema:CreativeWork
    269 sg:pub.10.1186/2193-1801-3-464 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002338437
    270 https://doi.org/10.1186/2193-1801-3-464
    271 rdf:type schema:CreativeWork
    272 grid-institutes:grid.411507.6 schema:alternateName Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India
    273 schema:name Cell Physiology Laboratory, Biochemistry Unit, Department of Zoology, Institute of Science, Banaras Hindu University, 221005, Varanasi, UP, India
    274 rdf:type schema:Organization
    275 grid-institutes:grid.416764.6 schema:alternateName Department of Reproductive Biomedicine, National Institute of Health and Family Welfare, Baba Gang Nath Marg, Munirka, 110067, New Delhi, India
    276 schema:name Department of Reproductive Biomedicine, National Institute of Health and Family Welfare, Baba Gang Nath Marg, Munirka, 110067, New Delhi, India
    277 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...