Studying the gut virome in the metagenomic era: challenges and perspectives View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-10-28

AUTHORS

Sanzhima Garmaeva, Trishla Sinha, Alexander Kurilshikov, Jingyuan Fu, Cisca Wijmenga, Alexandra Zhernakova

ABSTRACT

The human gut harbors a complex ecosystem of microorganisms, including bacteria and viruses. With the rise of next-generation sequencing technologies, we have seen a quantum leap in the study of human-gut-inhabiting bacteria, yet the viruses that infect these bacteria, known as bacteriophages, remain underexplored. In this review, we focus on what is known about the role of bacteriophages in human health and the technical challenges involved in studying the gut virome, of which they are a major component. Lastly, we discuss what can be learned from studies of bacteriophages in other ecosystems. More... »

PAGES

84

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12915-019-0704-y

    DOI

    http://dx.doi.org/10.1186/s12915-019-0704-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1122146598

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/31660953


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