The genome of the giant Nomura’s jellyfish sheds light on the early evolution of active predation View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Hak-Min Kim, Jessica A. Weber, Nayoung Lee, Seung Gu Park, Yun Sung Cho, Youngjune Bhak, Nayun Lee, Yeonsu Jeon, Sungwon Jeon, Victor Luria, Amir Karger, Marc W. Kirschner, Ye Jin Jo, Seonock Woo, Kyoungsoon Shin, Oksung Chung, Jae-Chun Ryu, Hyung-Soon Yim, Jung-Hyun Lee, Jeremy S. Edwards, Andrea Manica, Jong Bhak, Seungshic Yum

ABSTRACT

BACKGROUND: Unique among cnidarians, jellyfish have remarkable morphological and biochemical innovations that allow them to actively hunt in the water column and were some of the first animals to become free-swimming. The class Scyphozoa, or true jellyfish, are characterized by a predominant medusa life-stage consisting of a bell and venomous tentacles used for hunting and defense, as well as using pulsed jet propulsion for mobility. Here, we present the genome of the giant Nomura's jellyfish (Nemopilema nomurai) to understand the genetic basis of these key innovations. RESULTS: We sequenced the genome and transcriptomes of the bell and tentacles of the giant Nomura's jellyfish as well as transcriptomes across tissues and developmental stages of the Sanderia malayensis jellyfish. Analyses of the Nemopilema and other cnidarian genomes revealed adaptations associated with swimming, marked by codon bias in muscle contraction and expansion of neurotransmitter genes, along with expanded Myosin type II family and venom domains, possibly contributing to jellyfish mobility and active predation. We also identified gene family expansions of Wnt and posterior Hox genes and discovered the important role of retinoic acid signaling in this ancient lineage of metazoans, which together may be related to the unique jellyfish body plan (medusa formation). CONCLUSIONS: Taken together, the Nemopilema jellyfish genome and transcriptomes genetically confirm their unique morphological and physiological traits, which may have contributed to the success of jellyfish as early multi-cellular predators. More... »

PAGES

28

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12915-019-0643-7

    DOI

    http://dx.doi.org/10.1186/s12915-019-0643-7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1113115050

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30925871


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    566 schema:name Clinomics Inc., 44919, Ulsan, Republic of Korea
    567 Department of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), 44919, Ulsan, Republic of Korea
    568 Korean Genomics Industrialization Center (KOGIC), Ulsan National Institute of Science and Technology (UNIST), 44919, Ulsan, Republic of Korea
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    571 schema:name Department of Zoology, University of Cambridge, Downing Street, CB2 3EJ, Cambridge, UK
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