Tissue macrophages: heterogeneity and functions View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Siamon Gordon, Annette Plüddemann

ABSTRACT

Macrophages are present in all vertebrate tissues, from mid-gestation throughout life, constituting a widely dispersed organ system. They promote homeostasis by responding to internal and external changes within the body, not only as phagocytes in defence against microbes and in clearance of dead and senescent cells, but also through trophic, regulatory and repair functions. In this review, we describe macrophage phenotypic heterogeneity in different tissue environments, drawing particular attention to organ-specific functions. More... »

PAGES

53

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12915-017-0392-4

    DOI

    http://dx.doi.org/10.1186/s12915-017-0392-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1090296123

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28662662


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