Q&A: insulin secretion and type 2 diabetes: why do β-cells fail? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

James Cantley, Frances M. Ashcroft

ABSTRACT

N/A

PAGES

33

References to SciGraph publications

  • 2014-02. Are we overestimating the loss of beta cells in type 2 diabetes? in DIABETOLOGIA
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  • 1999-01. Concordance rate for Type II diabetes mellitus in monozygotic twins: actuarial analysis in DIABETOLOGIA
  • 2014-12. Reversible changes in pancreatic islet structure and function produced by elevated blood glucose in NATURE COMMUNICATIONS
  • 2011-10. Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol in DIABETOLOGIA
  • 2012-05-16. Diabetes in numbers in NATURE
  • 2013-01-06. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP in NATURE
  • 2010-10. Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring in NATURE
  • 2014-10. Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers in NATURE
  • 2014-03. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility in NATURE GENETICS
  • 2014-01. The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells in DIABETOLOGIA
  • 2012-05. Shedding pounds after going under the knife: Metabolic insights from cutting the gut in NATURE MEDICINE
  • 2006-01. Epidemiologic and economic consequences of the global epidemics of obesity and diabetes in NATURE MEDICINE
  • 2013-11. KATP channels and islet hormone secretion: new insights and controversies in NATURE REVIEWS ENDOCRINOLOGY
  • 2010-04. Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss in NATURE
  • 2006-12. Mechanisms linking obesity to insulin resistance and type 2 diabetes in NATURE
  • 2003-01. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes in DIABETOLOGIA
  • Journal

    TITLE

    BMC Biology

    ISSUE

    1

    VOLUME

    13

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12915-015-0140-6

    DOI

    http://dx.doi.org/10.1186/s12915-015-0140-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1030829879

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25982967


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    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12915-015-0140-6'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12915-015-0140-6'

    RDF/XML is a standard XML format for linked data.

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