Effect of fractioning on antibacterial activity of n-butanol fraction from Enantia chlorantha stem bark methanol extract View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Rebeca Madeleine Ebelle Etame, Raymond Simplice Mouokeu, Frank Stève Monthe Poundeu, Igor Kenfack Voukeng, Cedric Laurel Pouaha Cidjeu, Alembert Tchinda Tiabou, Abel Joel Gbaweng Yaya, Rosalie Anne Ngono Ngane, Jules Roger Kuiate, François Xavier Etoa

ABSTRACT

BACKGROUND: Enantia chlorantha is a plant belonging to Annonaceae Family. The Barks and leaves are used traditionally to treat infectious diseases. Earlier studies highlighted the antibacterial activity of stem barks methanol extract. This study is thus aimed at investigating the effect of fractionation on antibacterial activity of its n-butanol fraction. METHODS: The extract of E. chlorantha stem barks was obtained by maceration in methanol and then subjected to a liquid/liquid partition by successive depletion with solvents of increasing polarity. The n-butanol fraction was fractionated by adsorption chromatography on silica gel. A product was isolated from the dichloromethane/methanol (2%) fraction and the structure was determined on the basis of spectroscopic data; Proton Nuclear Magnetic Resonance (1H NMR), Carbon-13 Nuclear Magnetic Resonance (13C NMR), Heteronuclear Multiple Bond Correlation (HMBC), H-correlation spectroscopy (H-COSY), attached proton test (APT), heteronuclear multiple quantum coherence (HSQC). The antibacterial activity was evaluated by broth microdilution method against six reference strains and eight clinical bacterial strains. RESULTS: The n-butanol fraction was found to be active with MIC values ranging from 32 to 256 μg/mL. The FA sub-fraction was more efficient among the eight sub-fractions, the n-butanol fraction and comparable to Chloramphenicol used as reference antibiotic. The product obtained was elucidated as palmitin. The antibacterial activity of the latter was comparable to that of Chloramphenicol on one reference strain and 4 of the 6 clinical strains. CONCLUSION: The FA sub-fraction had better antibacterial activity than the n-butanol fraction and other sub-fractions, and possibly palmitin was the active substance responsible for the antibacterial activity of E. chlorantha. More... »

PAGES

56

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12906-019-2459-y

DOI

http://dx.doi.org/10.1186/s12906-019-2459-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112739081

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30866907


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0299", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Other Physical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/02", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Physical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "1-Butanol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Annonaceae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Spectroscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microbial Sensitivity Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Bark", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Extracts", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institut de Recherches M\u00e9dicales et d\u2019Etudes des Plantes M\u00e9dicinales", 
          "id": "https://www.grid.ac/institutes/grid.463347.1", 
          "name": [
            "Institute of Medical Research and Medicinal Plant Studies, (IMPM), Box 13033, Yaound\u00e9, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Etame", 
        "givenName": "Rebeca Madeleine Ebelle", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Douala", 
          "id": "https://www.grid.ac/institutes/grid.413096.9", 
          "name": [
            "Institute of Fisheries and Aquatic Sciences, University of Douala, Box 7236, Douala, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mouokeu", 
        "givenName": "Raymond Simplice", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Douala", 
          "id": "https://www.grid.ac/institutes/grid.413096.9", 
          "name": [
            "Faculty of Sciences, University of Douala, Box 24157, Douala, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Poundeu", 
        "givenName": "Frank St\u00e8ve Monthe", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universite De Dschang", 
          "id": "https://www.grid.ac/institutes/grid.8201.b", 
          "name": [
            "Faculty of Sciences, University of Dschang, Box 67, Dschang, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Voukeng", 
        "givenName": "Igor Kenfack", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Douala", 
          "id": "https://www.grid.ac/institutes/grid.413096.9", 
          "name": [
            "Faculty of Sciences, University of Douala, Box 24157, Douala, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cidjeu", 
        "givenName": "Cedric Laurel Pouaha", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Recherches M\u00e9dicales et d\u2019Etudes des Plantes M\u00e9dicinales", 
          "id": "https://www.grid.ac/institutes/grid.463347.1", 
          "name": [
            "Institute of Medical Research and Medicinal Plant Studies, (IMPM), Box 13033, Yaound\u00e9, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tiabou", 
        "givenName": "Alembert Tchinda", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Recherches M\u00e9dicales et d\u2019Etudes des Plantes M\u00e9dicinales", 
          "id": "https://www.grid.ac/institutes/grid.463347.1", 
          "name": [
            "Institute of Medical Research and Medicinal Plant Studies, (IMPM), Box 13033, Yaound\u00e9, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yaya", 
        "givenName": "Abel Joel Gbaweng", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Douala", 
          "id": "https://www.grid.ac/institutes/grid.413096.9", 
          "name": [
            "Faculty of Sciences, University of Douala, Box 24157, Douala, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ngane", 
        "givenName": "Rosalie Anne Ngono", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universite De Dschang", 
          "id": "https://www.grid.ac/institutes/grid.8201.b", 
          "name": [
            "Faculty of Sciences, University of Dschang, Box 67, Dschang, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kuiate", 
        "givenName": "Jules Roger", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e9 de Yaound\u00e9 I", 
          "id": "https://www.grid.ac/institutes/grid.412661.6", 
          "name": [
            "Faculty of Sciences, University of Yaound\u00e9 I, Box 812, Yaound\u00e9, PO, Cameroon"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Etoa", 
        "givenName": "Fran\u00e7ois Xavier", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/s12906-015-0541-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008622635", 
          "https://doi.org/10.1186/s12906-015-0541-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12906-015-0541-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008622635", 
          "https://doi.org/10.1186/s12906-015-0541-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-011-3557-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012784409", 
          "https://doi.org/10.1007/s00253-011-3557-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4236/jbise.2013.69107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016792566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1472-6882-13-164", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019587310", 
          "https://doi.org/10.1186/1472-6882-13-164"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1351/pac200577010007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022444091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5897/ajb2007.000-2397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027218115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12906-016-1509-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037206814", 
          "https://doi.org/10.1186/s12906-016-1509-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12906-016-1509-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037206814", 
          "https://doi.org/10.1186/s12906-016-1509-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mam.2005.07.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038428456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mam.2005.07.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038428456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.sajb.2008.02.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050148318"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b821648g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051514594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/b821648g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051514594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0030-1250027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057215569"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1684/abc.2012.0759", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078656204"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: Enantia chlorantha is a plant belonging to Annonaceae Family. The Barks and leaves are used traditionally to treat infectious diseases. Earlier studies highlighted the antibacterial activity of stem barks methanol extract. This study is thus aimed at investigating the effect of fractionation on antibacterial activity of its n-butanol fraction.\nMETHODS: The extract of E. chlorantha stem barks was obtained by maceration in methanol and then subjected to a liquid/liquid partition by successive depletion with solvents of increasing polarity. The n-butanol fraction was fractionated by adsorption chromatography on silica gel. A product was isolated from the dichloromethane/methanol (2%) fraction and the structure was determined on the basis of spectroscopic data; Proton Nuclear Magnetic Resonance (1H NMR), Carbon-13 Nuclear Magnetic Resonance (13C NMR), Heteronuclear Multiple Bond Correlation (HMBC), H-correlation spectroscopy (H-COSY), attached proton test (APT), heteronuclear multiple quantum coherence (HSQC). The antibacterial activity was evaluated by broth microdilution method against six reference strains and eight clinical bacterial strains.\nRESULTS: The n-butanol fraction was found to be active with MIC values ranging from 32 to 256\u2009\u03bcg/mL. The FA sub-fraction was more efficient among the eight sub-fractions, the n-butanol fraction and comparable to Chloramphenicol used as reference antibiotic. The product obtained was elucidated as palmitin. The antibacterial activity of the latter was comparable to that of Chloramphenicol on one reference strain and 4 of the 6 clinical strains.\nCONCLUSION: The FA sub-fraction had better antibacterial activity than the n-butanol fraction and other sub-fractions, and possibly palmitin was the active substance responsible for the antibacterial activity of E. chlorantha.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12906-019-2459-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1028418", 
        "issn": [
          "1472-6882"
        ], 
        "name": "BMC Complementary and Alternative Medicine", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "Effect of fractioning on antibacterial activity of n-butanol fraction from Enantia chlorantha stem bark methanol extract", 
    "pagination": "56", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12906-019-2459-y"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8f2fa33d9c00e0dd6568b83867d916a2aa32e5549b88a59b65865e9221fba36f"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112739081"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101088661"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30866907"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12906-019-2459-y", 
      "https://app.dimensions.ai/details/publication/pub.1112739081"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000376_0000000376/records_56176_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12906-019-2459-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12906-019-2459-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12906-019-2459-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12906-019-2459-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12906-019-2459-y'


 

This table displays all metadata directly associated to this object as RDF triples.

203 TRIPLES      21 PREDICATES      49 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12906-019-2459-y schema:about N185efb23f4374966bf2b6e1f93a78524
2 N3093713e0ac743fab745d7a6c369237c
3 N77905dd1314e40d7bf94f3be067e8590
4 N8678cc196c2242fb8a0c6ccf2b0417cb
5 Na2dce2f116d24a67acea45689cbb9cf7
6 Nf24f731e8ee44bb9acf6f8f766511913
7 Nf252fe8113794d5ca8d2370fb4d06080
8 Nf35f75dfdaa341c8af6e6a29ba0178b7
9 anzsrc-for:02
10 anzsrc-for:0299
11 schema:author Na835441f63f246e8919854f20fffdf1f
12 schema:citation sg:pub.10.1007/s00253-011-3557-z
13 sg:pub.10.1186/1472-6882-13-164
14 sg:pub.10.1186/s12906-015-0541-7
15 sg:pub.10.1186/s12906-016-1509-y
16 https://doi.org/10.1016/j.mam.2005.07.008
17 https://doi.org/10.1016/j.sajb.2008.02.004
18 https://doi.org/10.1039/b821648g
19 https://doi.org/10.1055/s-0030-1250027
20 https://doi.org/10.1351/pac200577010007
21 https://doi.org/10.1684/abc.2012.0759
22 https://doi.org/10.4236/jbise.2013.69107
23 https://doi.org/10.5897/ajb2007.000-2397
24 schema:datePublished 2019-12
25 schema:datePublishedReg 2019-12-01
26 schema:description BACKGROUND: Enantia chlorantha is a plant belonging to Annonaceae Family. The Barks and leaves are used traditionally to treat infectious diseases. Earlier studies highlighted the antibacterial activity of stem barks methanol extract. This study is thus aimed at investigating the effect of fractionation on antibacterial activity of its n-butanol fraction. METHODS: The extract of E. chlorantha stem barks was obtained by maceration in methanol and then subjected to a liquid/liquid partition by successive depletion with solvents of increasing polarity. The n-butanol fraction was fractionated by adsorption chromatography on silica gel. A product was isolated from the dichloromethane/methanol (2%) fraction and the structure was determined on the basis of spectroscopic data; Proton Nuclear Magnetic Resonance (1H NMR), Carbon-13 Nuclear Magnetic Resonance (13C NMR), Heteronuclear Multiple Bond Correlation (HMBC), H-correlation spectroscopy (H-COSY), attached proton test (APT), heteronuclear multiple quantum coherence (HSQC). The antibacterial activity was evaluated by broth microdilution method against six reference strains and eight clinical bacterial strains. RESULTS: The n-butanol fraction was found to be active with MIC values ranging from 32 to 256 μg/mL. The FA sub-fraction was more efficient among the eight sub-fractions, the n-butanol fraction and comparable to Chloramphenicol used as reference antibiotic. The product obtained was elucidated as palmitin. The antibacterial activity of the latter was comparable to that of Chloramphenicol on one reference strain and 4 of the 6 clinical strains. CONCLUSION: The FA sub-fraction had better antibacterial activity than the n-butanol fraction and other sub-fractions, and possibly palmitin was the active substance responsible for the antibacterial activity of E. chlorantha.
27 schema:genre research_article
28 schema:inLanguage en
29 schema:isAccessibleForFree true
30 schema:isPartOf Nb2249ace83e648fc8e5dc5f71c6ccf24
31 Ne2bbafce92b6417fa2e5f892c5183654
32 sg:journal.1028418
33 schema:name Effect of fractioning on antibacterial activity of n-butanol fraction from Enantia chlorantha stem bark methanol extract
34 schema:pagination 56
35 schema:productId N0b8aadb44be44bacb7545040aab20e2b
36 N0ced738d629043e493255b3aee780c0e
37 N6d9b077404b44c0ab2ec4f2dcd45d02a
38 N96d7537ba1d44188af24529e0a5c62ad
39 Nebe32226a5c64c2c91352c623a269235
40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112739081
41 https://doi.org/10.1186/s12906-019-2459-y
42 schema:sdDatePublished 2019-04-15T09:19
43 schema:sdLicense https://scigraph.springernature.com/explorer/license/
44 schema:sdPublisher Nb101b6ee40e144d8998e9a00935102cb
45 schema:url https://link.springer.com/10.1186%2Fs12906-019-2459-y
46 sgo:license sg:explorer/license/
47 sgo:sdDataset articles
48 rdf:type schema:ScholarlyArticle
49 N094223242cc2483e83b1dc8f218b7c4d schema:affiliation https://www.grid.ac/institutes/grid.463347.1
50 schema:familyName Yaya
51 schema:givenName Abel Joel Gbaweng
52 rdf:type schema:Person
53 N0b8aadb44be44bacb7545040aab20e2b schema:name pubmed_id
54 schema:value 30866907
55 rdf:type schema:PropertyValue
56 N0ced738d629043e493255b3aee780c0e schema:name nlm_unique_id
57 schema:value 101088661
58 rdf:type schema:PropertyValue
59 N14555e968b1a43708c5682036b7cdeef schema:affiliation https://www.grid.ac/institutes/grid.412661.6
60 schema:familyName Etoa
61 schema:givenName François Xavier
62 rdf:type schema:Person
63 N185efb23f4374966bf2b6e1f93a78524 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name 1-Butanol
65 rdf:type schema:DefinedTerm
66 N21dbcd3400ad49bbb0ce4daada91f047 schema:affiliation https://www.grid.ac/institutes/grid.413096.9
67 schema:familyName Cidjeu
68 schema:givenName Cedric Laurel Pouaha
69 rdf:type schema:Person
70 N2bf9cbcef8a2466486af212c3901e4e5 schema:affiliation https://www.grid.ac/institutes/grid.463347.1
71 schema:familyName Etame
72 schema:givenName Rebeca Madeleine Ebelle
73 rdf:type schema:Person
74 N3093713e0ac743fab745d7a6c369237c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Microbial Sensitivity Tests
76 rdf:type schema:DefinedTerm
77 N33e2e2453e174966aa257d8935ad0841 rdf:first N094223242cc2483e83b1dc8f218b7c4d
78 rdf:rest Naf70a224a3954f24bd5e9fc19a6d9035
79 N40b14f20004d47d8a2c22775ef530bd5 rdf:first Nc398ea645c824766a0ae284abcffdd57
80 rdf:rest N33e2e2453e174966aa257d8935ad0841
81 N4a5c1a901c5e43f995ec2f4bfae9c545 schema:affiliation https://www.grid.ac/institutes/grid.413096.9
82 schema:familyName Poundeu
83 schema:givenName Frank Stève Monthe
84 rdf:type schema:Person
85 N5bddc16b8f224d05adddbbf0d95557cc rdf:first Nc133451aa2f34d1480c78cd98bca5bb3
86 rdf:rest Naa92edfaae2c4376adf3921f28e8af59
87 N6457739970d04e008f2af14f26c93997 schema:affiliation https://www.grid.ac/institutes/grid.413096.9
88 schema:familyName Ngane
89 schema:givenName Rosalie Anne Ngono
90 rdf:type schema:Person
91 N655d2e9c644548c080d2914944b3a14e rdf:first N14555e968b1a43708c5682036b7cdeef
92 rdf:rest rdf:nil
93 N6d9b077404b44c0ab2ec4f2dcd45d02a schema:name doi
94 schema:value 10.1186/s12906-019-2459-y
95 rdf:type schema:PropertyValue
96 N77905dd1314e40d7bf94f3be067e8590 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Annonaceae
98 rdf:type schema:DefinedTerm
99 N7d89c048d01b446fbaee6d966837ff64 rdf:first N8c27bee78ab048a6ab4e4c22a0a0c326
100 rdf:rest N655d2e9c644548c080d2914944b3a14e
101 N8678cc196c2242fb8a0c6ccf2b0417cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Bacteria
103 rdf:type schema:DefinedTerm
104 N8c27bee78ab048a6ab4e4c22a0a0c326 schema:affiliation https://www.grid.ac/institutes/grid.8201.b
105 schema:familyName Kuiate
106 schema:givenName Jules Roger
107 rdf:type schema:Person
108 N96d7537ba1d44188af24529e0a5c62ad schema:name readcube_id
109 schema:value 8f2fa33d9c00e0dd6568b83867d916a2aa32e5549b88a59b65865e9221fba36f
110 rdf:type schema:PropertyValue
111 N9a2dddd474264629ac5877aeb70464ee rdf:first Nda40d82078274ca28186a651c51ebf99
112 rdf:rest Ne3d15a236d2b4c0488c29b6f80f99047
113 Na2dce2f116d24a67acea45689cbb9cf7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Plant Bark
115 rdf:type schema:DefinedTerm
116 Na835441f63f246e8919854f20fffdf1f rdf:first N2bf9cbcef8a2466486af212c3901e4e5
117 rdf:rest N9a2dddd474264629ac5877aeb70464ee
118 Naa92edfaae2c4376adf3921f28e8af59 rdf:first N21dbcd3400ad49bbb0ce4daada91f047
119 rdf:rest N40b14f20004d47d8a2c22775ef530bd5
120 Naf70a224a3954f24bd5e9fc19a6d9035 rdf:first N6457739970d04e008f2af14f26c93997
121 rdf:rest N7d89c048d01b446fbaee6d966837ff64
122 Nb101b6ee40e144d8998e9a00935102cb schema:name Springer Nature - SN SciGraph project
123 rdf:type schema:Organization
124 Nb2249ace83e648fc8e5dc5f71c6ccf24 schema:issueNumber 1
125 rdf:type schema:PublicationIssue
126 Nc133451aa2f34d1480c78cd98bca5bb3 schema:affiliation https://www.grid.ac/institutes/grid.8201.b
127 schema:familyName Voukeng
128 schema:givenName Igor Kenfack
129 rdf:type schema:Person
130 Nc398ea645c824766a0ae284abcffdd57 schema:affiliation https://www.grid.ac/institutes/grid.463347.1
131 schema:familyName Tiabou
132 schema:givenName Alembert Tchinda
133 rdf:type schema:Person
134 Nda40d82078274ca28186a651c51ebf99 schema:affiliation https://www.grid.ac/institutes/grid.413096.9
135 schema:familyName Mouokeu
136 schema:givenName Raymond Simplice
137 rdf:type schema:Person
138 Ne2bbafce92b6417fa2e5f892c5183654 schema:volumeNumber 19
139 rdf:type schema:PublicationVolume
140 Ne3d15a236d2b4c0488c29b6f80f99047 rdf:first N4a5c1a901c5e43f995ec2f4bfae9c545
141 rdf:rest N5bddc16b8f224d05adddbbf0d95557cc
142 Nebe32226a5c64c2c91352c623a269235 schema:name dimensions_id
143 schema:value pub.1112739081
144 rdf:type schema:PropertyValue
145 Nf24f731e8ee44bb9acf6f8f766511913 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Anti-Bacterial Agents
147 rdf:type schema:DefinedTerm
148 Nf252fe8113794d5ca8d2370fb4d06080 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Magnetic Resonance Spectroscopy
150 rdf:type schema:DefinedTerm
151 Nf35f75dfdaa341c8af6e6a29ba0178b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Plant Extracts
153 rdf:type schema:DefinedTerm
154 anzsrc-for:02 schema:inDefinedTermSet anzsrc-for:
155 schema:name Physical Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:0299 schema:inDefinedTermSet anzsrc-for:
158 schema:name Other Physical Sciences
159 rdf:type schema:DefinedTerm
160 sg:journal.1028418 schema:issn 1472-6882
161 schema:name BMC Complementary and Alternative Medicine
162 rdf:type schema:Periodical
163 sg:pub.10.1007/s00253-011-3557-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1012784409
164 https://doi.org/10.1007/s00253-011-3557-z
165 rdf:type schema:CreativeWork
166 sg:pub.10.1186/1472-6882-13-164 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019587310
167 https://doi.org/10.1186/1472-6882-13-164
168 rdf:type schema:CreativeWork
169 sg:pub.10.1186/s12906-015-0541-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008622635
170 https://doi.org/10.1186/s12906-015-0541-7
171 rdf:type schema:CreativeWork
172 sg:pub.10.1186/s12906-016-1509-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1037206814
173 https://doi.org/10.1186/s12906-016-1509-y
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/j.mam.2005.07.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038428456
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/j.sajb.2008.02.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050148318
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1039/b821648g schema:sameAs https://app.dimensions.ai/details/publication/pub.1051514594
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1055/s-0030-1250027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057215569
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1351/pac200577010007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022444091
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1684/abc.2012.0759 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078656204
186 rdf:type schema:CreativeWork
187 https://doi.org/10.4236/jbise.2013.69107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016792566
188 rdf:type schema:CreativeWork
189 https://doi.org/10.5897/ajb2007.000-2397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027218115
190 rdf:type schema:CreativeWork
191 https://www.grid.ac/institutes/grid.412661.6 schema:alternateName Université de Yaoundé I
192 schema:name Faculty of Sciences, University of Yaoundé I, Box 812, Yaoundé, PO, Cameroon
193 rdf:type schema:Organization
194 https://www.grid.ac/institutes/grid.413096.9 schema:alternateName University of Douala
195 schema:name Faculty of Sciences, University of Douala, Box 24157, Douala, PO, Cameroon
196 Institute of Fisheries and Aquatic Sciences, University of Douala, Box 7236, Douala, PO, Cameroon
197 rdf:type schema:Organization
198 https://www.grid.ac/institutes/grid.463347.1 schema:alternateName Institut de Recherches Médicales et d’Etudes des Plantes Médicinales
199 schema:name Institute of Medical Research and Medicinal Plant Studies, (IMPM), Box 13033, Yaoundé, PO, Cameroon
200 rdf:type schema:Organization
201 https://www.grid.ac/institutes/grid.8201.b schema:alternateName Universite De Dschang
202 schema:name Faculty of Sciences, University of Dschang, Box 67, Dschang, PO, Cameroon
203 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...