Ontology type: schema:ScholarlyArticle Open Access: True
2019-12
AUTHORSJi-Youn Hong, Jung-Seok Lee, Seong-Ho Choi, Hyun-Seung Shin, Jung-Chul Park, Seung-Il Shin, Jong-Hyuk Chung
ABSTRACTBACKGROUND: To evaluate gingival inflammation from fixed-dose combinations of vitamin C, vitamin E, lysozyme and carbazochrome (CELC) in the treatment of chronic periodontitis following scaling and root planing. METHODS: One hundred patients were randomly assigned to receive CELC (test) or placebo (control) for the first 4 weeks at a 1:1 ratio, and both groups received CELC for the remaining 4 weeks. Primary outcome was the mean change in the gingival index (GI) after 4 weeks. Secondary outcomes included mean change in GI after 8 weeks and plaque index, probing depth, clinical attachment level, and VAS at 4 weeks and 8 weeks. RESULTS: Ninety-three patients completed the study. The GI in the test group significantly decreased after 4 weeks (p < 0.001) and 8 weeks (p < 0.001). The mean change from baseline in GI significantly decreased in the test group compared to the control group after 4 weeks (p = 0.015). In the GEE model adjusting for age, gender and visits, the test group showed 2.5 times GI improvement compared to the control group (p = 0.022). CONCLUSIONS: Within the study, CELC showed a significant reduction in gingival inflammation compared with a placebo. Other parameters, however, were similar between groups. TRIAL REGISTRATION: KCT0001366 (Clinical Research Information Service, Republic of Korea) and 29 Jan 2015, retrospectively registered. More... »
PAGES40
http://scigraph.springernature.com/pub.10.1186/s12903-019-0728-2
DOIhttp://dx.doi.org/10.1186/s12903-019-0728-2
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1112606536
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30845920
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Kyung Hee University",
"id": "https://www.grid.ac/institutes/grid.289247.2",
"name": [
"Department of Periodontology, Periodontal-Implant Clinical Research Institute, School of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, South Korea"
],
"type": "Organization"
},
"familyName": "Hong",
"givenName": "Ji-Youn",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Yonsei University",
"id": "https://www.grid.ac/institutes/grid.15444.30",
"name": [
"Department of Periodontology, College of Dentistry, Yonsei University, Seoul, South Korea"
],
"type": "Organization"
},
"familyName": "Lee",
"givenName": "Jung-Seok",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Yonsei University",
"id": "https://www.grid.ac/institutes/grid.15444.30",
"name": [
"Department of Periodontology, College of Dentistry, Yonsei University, Seoul, South Korea"
],
"type": "Organization"
},
"familyName": "Choi",
"givenName": "Seong-Ho",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Dankook University",
"id": "https://www.grid.ac/institutes/grid.411982.7",
"name": [
"Department of Periodontology, College of Dentistry, Dankook University, Cheonan, South Korea"
],
"type": "Organization"
},
"familyName": "Shin",
"givenName": "Hyun-Seung",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Dankook University",
"id": "https://www.grid.ac/institutes/grid.411982.7",
"name": [
"Department of Periodontology, College of Dentistry, Dankook University, Cheonan, South Korea"
],
"type": "Organization"
},
"familyName": "Park",
"givenName": "Jung-Chul",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Kyung Hee University",
"id": "https://www.grid.ac/institutes/grid.289247.2",
"name": [
"Department of Periodontology, Periodontal-Implant Clinical Research Institute, School of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, South Korea"
],
"type": "Organization"
},
"familyName": "Shin",
"givenName": "Seung-Il",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Kyung Hee University",
"id": "https://www.grid.ac/institutes/grid.289247.2",
"name": [
"Department of Periodontology, Periodontal-Implant Clinical Research Institute, School of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, 02447, Seoul, South Korea"
],
"type": "Organization"
},
"familyName": "Chung",
"givenName": "Jong-Hyuk",
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1034/j.1600-051x.29.s2.4.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003212020"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3945/jn.114.203703",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004874323"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-9969(93)90126-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006909182"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0757.2012.00458.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009800645"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.0303-6979.2004.00430.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013410112"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00210-003-0785-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020352677",
"https://doi.org/10.1007/s00210-003-0785-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.14219/jada.archive.2009.0131",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021152315"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/14651858.cd003974",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022171228"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0757.2006.00166.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024965461"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/14651858.cd003974.pub3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026346604"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0757.2006.00178.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026692366"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.1993.tb00330.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028137519"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.1993.tb00330.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028137519"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.archoralbio.2015.05.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028747174"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1034/j.1601-0825.2002.1o781.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033606749"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1749-6632.1987.tb23761.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035720505"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1155/2012/142702",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040257521"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0757.2008.00252.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040431973"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.1986.tb01433.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041645400"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.1986.tb01433.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041645400"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1034/j.1600-0757.2000.2240112.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043161698"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-0757.1997.tb00189.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045840317"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.2010.01663.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046774714"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.2005.00785.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049379291"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1600-051x.2005.00785.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049379291"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2567.2000.00070.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050468667"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/00220345910700121101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063640196"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/00220345910700121101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1063640196"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1902/jop.2000.71.8.1215",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1068734276"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1902/jop.2002.73.9.975",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1068734776"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1902/jop.2007.060465",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1068736085"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1902/jop.2008.080213",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1068736522"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1902/jop.2013.120727",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1068737748"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/137.3.657",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1077374964"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077843096",
"type": "CreativeWork"
}
],
"datePublished": "2019-12",
"datePublishedReg": "2019-12-01",
"description": "BACKGROUND: To evaluate gingival inflammation from fixed-dose combinations of vitamin C, vitamin E, lysozyme and carbazochrome (CELC) in the treatment of chronic periodontitis following scaling and root planing.\nMETHODS: One hundred patients were randomly assigned to receive CELC (test) or placebo (control) for the first 4\u2009weeks at a 1:1 ratio, and both groups received CELC for the remaining 4\u2009weeks. Primary outcome was the mean change in the gingival index (GI) after 4\u2009weeks. Secondary outcomes included mean change in GI after 8\u2009weeks and plaque index, probing depth, clinical attachment level, and VAS at 4\u2009weeks and 8\u2009weeks.\nRESULTS: Ninety-three patients completed the study. The GI in the test group significantly decreased after 4\u2009weeks (p\u00a0<\u20090.001) and 8\u2009weeks (p\u00a0<\u20090.001). The mean change from baseline in GI significantly decreased in the test group compared to the control group after 4\u2009weeks (p\u00a0=\u20090.015). In the GEE model adjusting for age, gender and visits, the test group showed 2.5 times GI improvement compared to the control group (p\u00a0=\u20090.022).\nCONCLUSIONS: Within the study, CELC showed a significant reduction in gingival inflammation compared with a placebo. Other parameters, however, were similar between groups.\nTRIAL REGISTRATION: KCT0001366 (Clinical Research Information Service, Republic of Korea) and 29 Jan 2015, retrospectively registered.",
"genre": "research_article",
"id": "sg:pub.10.1186/s12903-019-0728-2",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1028434",
"issn": [
"1472-6831"
],
"name": "BMC Oral Health",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "19"
}
],
"name": "A randomized, double-blind, placebo-controlled multicenter study for evaluating the effects of fixed-dose combinations of vitamin C, vitamin E, lysozyme, and carbazochrome on gingival inflammation in chronic periodontitis patients",
"pagination": "40",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"c5c655425b646f0320d3147aad6898dffc3661cb2264ac676bc0417b0c7eb502"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30845920"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"101088684"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s12903-019-0728-2"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1112606536"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s12903-019-0728-2",
"https://app.dimensions.ai/details/publication/pub.1112606536"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T13:20",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78965_00000001.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1186%2Fs12903-019-0728-2"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12903-019-0728-2'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12903-019-0728-2'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12903-019-0728-2'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12903-019-0728-2'
This table displays all metadata directly associated to this object as RDF triples.
202 TRIPLES
21 PREDICATES
60 URIs
21 LITERALS
9 BLANK NODES