The influence of adipose-derived stromal vascular fraction cells on the treatment of knee osteoarthritis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-04-06

AUTHORS

Masanori Tsubosaka, Tomoyuki Matsumoto, Satoshi Sobajima, Takehiko Matsushita, Hideki Iwaguro, Ryosuke Kuroda

ABSTRACT

BACKGROUND: Adipose-derived stromal vascular fraction (SVF) cells are a mixed cell population that includes cells with multilineage potential, similar to bone marrow-derived mesenchymal stem cells. Our purpose is to investigate the influence of SVF cells in patients with knee osteoarthritis (OA) and the short-term treatment effects. METHODS: Fifty-seven patients were enrolled and treated with intra-articular injection of 2.5 × 107 SVF cells into the knee joint between September 2017 and March 2018. All patients were followed up for 12 months or longer. Mean age at treatment and follow-up period were 69.4 ± 6.9 years and 13.7 ± 2.0 months, respectively. The mean preoperative hip-knee-ankle angle was 6.7 ± 3.6°. SVF cells were prepared using the Celution®800/CRS system from the patients' abdominal or breech subcutaneous fat. The mean SVF cell viability was 90.6 ± 2.7%. Clinical evaluations were performed for range of motion, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analog scale (VAS) for pain, and the Knee injury and Osteoarthritis Score (KOOS). Imaging evaluations, which included the hip-knee-ankle angle assessed via radiography, and T2 mapping value using a 1.5-T magnetic resonance imaging unit were also assessed. Both clinical and imaging evaluations were performed preoperatively, 1, 3, 6, and 12 months postoperatively, and compared among all timepoints (p < 0.05). RESULTS: Knee extension angle at 6 and 12 months postoperatively was significantly better than the preoperative angle. Total WOMAC, VAS, and KOOS scores at 1, 3, 6 and 12 months postoperatively were significantly better than preoperative scores. There was no significant difference in hip-knee-ankle angle among the five time periods. T2 mapping values of lateral femur and tibia were significantly higher 12 months postoperatively than preoperatively. CONCLUSIONS: The short-term clinical effects of intra-articular SVF cell injection on knee OA were excellent. Intra-articular SVF cell injection is a novel and innovative approach for treating patients with knee OA. More... »

PAGES

207

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12891-020-03231-3

DOI

http://dx.doi.org/10.1186/s12891-020-03231-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1126175454

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32252731


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adipose Tissue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Injections, Intra-Articular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Knee Joint", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mesenchymal Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mesenchymal Stem Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Osteoarthritis, Knee", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pain Measurement", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radiography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Range of Motion, Articular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan", 
            "Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsubosaka", 
        "givenName": "Masanori", 
        "id": "sg:person.014154544361.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014154544361.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan", 
          "id": "http://www.grid.ac/institutes/grid.31432.37", 
          "name": [
            "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsumoto", 
        "givenName": "Tomoyuki", 
        "id": "sg:person.0673774654.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673774654.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sobajima", 
        "givenName": "Satoshi", 
        "id": "sg:person.0722327110.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722327110.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan", 
          "id": "http://www.grid.ac/institutes/grid.31432.37", 
          "name": [
            "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsushita", 
        "givenName": "Takehiko", 
        "id": "sg:person.01056105637.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056105637.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwaguro", 
        "givenName": "Hideki", 
        "id": "sg:person.01011105227.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011105227.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan", 
          "id": "http://www.grid.ac/institutes/grid.31432.37", 
          "name": [
            "Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kuroda", 
        "givenName": "Ryosuke", 
        "id": "sg:person.01025022257.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025022257.04"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00264-018-4099-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106150032", 
          "https://doi.org/10.1007/s00264-018-4099-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.3758/brm.41.4.1149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019543365", 
          "https://doi.org/10.3758/brm.41.4.1149"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-04-06", 
    "datePublishedReg": "2020-04-06", 
    "description": "BACKGROUND: Adipose-derived stromal vascular fraction (SVF) cells are a mixed cell population that includes cells with multilineage potential, similar to bone marrow-derived mesenchymal stem cells. Our purpose is to investigate the influence of SVF cells in patients with knee osteoarthritis (OA) and the short-term treatment effects.\nMETHODS: Fifty-seven patients were enrolled and treated with intra-articular injection of 2.5\u2009\u00d7\u2009107 SVF cells into the knee joint between September 2017 and March 2018. All patients were followed up for 12\u2009months or longer. Mean age at treatment and follow-up period were 69.4\u2009\u00b1\u20096.9\u2009years and 13.7\u2009\u00b1\u20092.0\u2009months, respectively. The mean preoperative hip-knee-ankle angle was 6.7\u2009\u00b1\u20093.6\u00b0. SVF cells were prepared using the Celution\u00ae800/CRS system from the patients' abdominal or breech subcutaneous fat. The mean SVF cell viability was 90.6\u2009\u00b1\u20092.7%. Clinical evaluations were performed for range of motion, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analog scale (VAS) for pain, and the Knee injury and Osteoarthritis Score (KOOS). Imaging evaluations, which included the hip-knee-ankle angle assessed via radiography, and T2 mapping value using a 1.5-T magnetic resonance imaging unit were also assessed. Both clinical and imaging evaluations were performed preoperatively, 1, 3, 6, and 12\u2009months postoperatively, and compared among all timepoints (p\u2009<\u20090.05).\nRESULTS: Knee extension angle at 6 and 12\u2009months postoperatively was significantly better than the preoperative angle. Total WOMAC, VAS, and KOOS scores at 1, 3, 6 and 12\u2009months postoperatively were significantly better than preoperative scores. There was no significant difference in hip-knee-ankle angle among the five time periods. T2 mapping values of lateral femur and tibia were significantly higher 12\u2009months postoperatively than preoperatively.\nCONCLUSIONS: The short-term clinical effects of intra-articular SVF cell injection on knee OA were excellent. Intra-articular SVF cell injection is a novel and innovative approach for treating patients with knee OA.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12891-020-03231-3", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024957", 
        "issn": [
          "1471-2474"
        ], 
        "name": "BMC Musculoskeletal Disorders", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "21"
      }
    ], 
    "keywords": [
      "visual analog scale", 
      "adipose-derived stromal vascular fraction cells", 
      "knee osteoarthritis", 
      "stromal vascular fraction cells", 
      "ankle angle", 
      "SVF cells", 
      "cell injection", 
      "McMaster Universities Osteoarthritis Index", 
      "short-term clinical effects", 
      "fraction cells", 
      "intra-articular injection", 
      "short-term treatment effects", 
      "range of motion", 
      "bone marrow-derived mesenchymal stem cells", 
      "knee extension angle", 
      "marrow-derived mesenchymal stem cells", 
      "T2 mapping values", 
      "total WOMAC", 
      "Osteoarthritis Index", 
      "KOOS scores", 
      "preoperative angle", 
      "preoperative scores", 
      "knee injuries", 
      "clinical effects", 
      "analog scale", 
      "osteoarthritis score", 
      "clinical evaluation", 
      "Western Ontario", 
      "lateral femur", 
      "patients", 
      "osteoarthritis", 
      "mesenchymal stem cells", 
      "knee joint", 
      "subcutaneous fat", 
      "months", 
      "extension angle", 
      "cell populations", 
      "magnetic resonance (MR) imaging unit", 
      "treatment effects", 
      "significant differences", 
      "mixed cell populations", 
      "multilineage potential", 
      "injection", 
      "cell viability", 
      "scores", 
      "stem cells", 
      "mapping values", 
      "cells", 
      "treatment", 
      "CRS system", 
      "imaging unit", 
      "Celution", 
      "WOMAC", 
      "pain", 
      "injury", 
      "evaluation", 
      "timepoints", 
      "tibia", 
      "femur", 
      "time period", 
      "age", 
      "period", 
      "radiography", 
      "fat", 
      "effect", 
      "population", 
      "years", 
      "index", 
      "joints", 
      "differences", 
      "viability", 
      "innovative approach", 
      "Ontario", 
      "purpose", 
      "values", 
      "units", 
      "potential", 
      "influence", 
      "scale", 
      "angle", 
      "approach", 
      "range", 
      "system", 
      "motion", 
      "vascular fraction (SVF) cells", 
      "breech subcutaneous fat", 
      "mean SVF cell viability", 
      "SVF cell viability", 
      "Universities Osteoarthritis Index", 
      "resonance imaging unit", 
      "intra-articular SVF cell injection", 
      "SVF cell injection"
    ], 
    "name": "The influence of adipose-derived stromal vascular fraction cells on the treatment of knee osteoarthritis", 
    "pagination": "207", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1126175454"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12891-020-03231-3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "32252731"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12891-020-03231-3", 
      "https://app.dimensions.ai/details/publication/pub.1126175454"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_852.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12891-020-03231-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12891-020-03231-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12891-020-03231-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12891-020-03231-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12891-020-03231-3'


 

This table displays all metadata directly associated to this object as RDF triples.

264 TRIPLES      22 PREDICATES      136 URIs      126 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12891-020-03231-3 schema:about N23cfdc79d3584c79bd045ad884bfe5c8
2 N27f3cd26c70748e6b8b38874ec681645
3 N5a017c48760d441fb74f14b5bc488928
4 N7940ddcd143a4713a0c0e6fab9ad4c3c
5 Nad44991f70ce4bf0a0badfdbb5693547
6 Nba4ee61f470942fbbc0fe7f946063024
7 Nc36b2576638c4adfa2888f8fe8f8e52e
8 Nc6c4ebd7e642471581fe425be0167cbb
9 Nc7f50d4827924f7bb91a2a6fd85bde94
10 Ncb41df29eafc49ff920f3f09718fb618
11 Nce958d6fcce24752b28c6f036395680d
12 Ncf1706a27d914cdb8a7e0090e4a052dc
13 Ne11b406276f14fbeb782ece5122e7475
14 Nedc611b29fdd40ee989895f867016ea4
15 Nfc3df015565444dba32d2df9d9a2c98e
16 Nfd84e252426c404e82a0b9220ba71efb
17 anzsrc-for:11
18 anzsrc-for:1103
19 schema:author N7d1d243a7e364eb8bcc5a3e88fa6dba2
20 schema:citation sg:pub.10.1007/s00264-018-4099-0
21 sg:pub.10.3758/brm.41.4.1149
22 schema:datePublished 2020-04-06
23 schema:datePublishedReg 2020-04-06
24 schema:description BACKGROUND: Adipose-derived stromal vascular fraction (SVF) cells are a mixed cell population that includes cells with multilineage potential, similar to bone marrow-derived mesenchymal stem cells. Our purpose is to investigate the influence of SVF cells in patients with knee osteoarthritis (OA) and the short-term treatment effects. METHODS: Fifty-seven patients were enrolled and treated with intra-articular injection of 2.5 × 10<sup>7</sup> SVF cells into the knee joint between September 2017 and March 2018. All patients were followed up for 12 months or longer. Mean age at treatment and follow-up period were 69.4 ± 6.9 years and 13.7 ± 2.0 months, respectively. The mean preoperative hip-knee-ankle angle was 6.7 ± 3.6°. SVF cells were prepared using the Celution®800/CRS system from the patients' abdominal or breech subcutaneous fat. The mean SVF cell viability was 90.6 ± 2.7%. Clinical evaluations were performed for range of motion, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analog scale (VAS) for pain, and the Knee injury and Osteoarthritis Score (KOOS). Imaging evaluations, which included the hip-knee-ankle angle assessed via radiography, and T2 mapping value using a 1.5-T magnetic resonance imaging unit were also assessed. Both clinical and imaging evaluations were performed preoperatively, 1, 3, 6, and 12 months postoperatively, and compared among all timepoints (p &lt; 0.05). RESULTS: Knee extension angle at 6 and 12 months postoperatively was significantly better than the preoperative angle. Total WOMAC, VAS, and KOOS scores at 1, 3, 6 and 12 months postoperatively were significantly better than preoperative scores. There was no significant difference in hip-knee-ankle angle among the five time periods. T2 mapping values of lateral femur and tibia were significantly higher 12 months postoperatively than preoperatively. CONCLUSIONS: The short-term clinical effects of intra-articular SVF cell injection on knee OA were excellent. Intra-articular SVF cell injection is a novel and innovative approach for treating patients with knee OA.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree true
28 schema:isPartOf N191658f030244f8ba1e4db33d1213e89
29 N66d0015d9b0d4454a1beae33148d53bf
30 sg:journal.1024957
31 schema:keywords CRS system
32 Celution
33 KOOS scores
34 McMaster Universities Osteoarthritis Index
35 Ontario
36 Osteoarthritis Index
37 SVF cell injection
38 SVF cell viability
39 SVF cells
40 T2 mapping values
41 Universities Osteoarthritis Index
42 WOMAC
43 Western Ontario
44 adipose-derived stromal vascular fraction cells
45 age
46 analog scale
47 angle
48 ankle angle
49 approach
50 bone marrow-derived mesenchymal stem cells
51 breech subcutaneous fat
52 cell injection
53 cell populations
54 cell viability
55 cells
56 clinical effects
57 clinical evaluation
58 differences
59 effect
60 evaluation
61 extension angle
62 fat
63 femur
64 fraction cells
65 imaging unit
66 index
67 influence
68 injection
69 injury
70 innovative approach
71 intra-articular SVF cell injection
72 intra-articular injection
73 joints
74 knee extension angle
75 knee injuries
76 knee joint
77 knee osteoarthritis
78 lateral femur
79 magnetic resonance (MR) imaging unit
80 mapping values
81 marrow-derived mesenchymal stem cells
82 mean SVF cell viability
83 mesenchymal stem cells
84 mixed cell populations
85 months
86 motion
87 multilineage potential
88 osteoarthritis
89 osteoarthritis score
90 pain
91 patients
92 period
93 population
94 potential
95 preoperative angle
96 preoperative scores
97 purpose
98 radiography
99 range
100 range of motion
101 resonance imaging unit
102 scale
103 scores
104 short-term clinical effects
105 short-term treatment effects
106 significant differences
107 stem cells
108 stromal vascular fraction cells
109 subcutaneous fat
110 system
111 tibia
112 time period
113 timepoints
114 total WOMAC
115 treatment
116 treatment effects
117 units
118 values
119 vascular fraction (SVF) cells
120 viability
121 visual analog scale
122 years
123 schema:name The influence of adipose-derived stromal vascular fraction cells on the treatment of knee osteoarthritis
124 schema:pagination 207
125 schema:productId N7775e49e6de9412a9e9c216e7987ac97
126 N7cdd2c2282544d7681c15e8efb77c5d5
127 Na81043ecc45a4cd49de0736133f38ba6
128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1126175454
129 https://doi.org/10.1186/s12891-020-03231-3
130 schema:sdDatePublished 2022-01-01T18:58
131 schema:sdLicense https://scigraph.springernature.com/explorer/license/
132 schema:sdPublisher N528e63e100994eddbf89e6343e536cb6
133 schema:url https://doi.org/10.1186/s12891-020-03231-3
134 sgo:license sg:explorer/license/
135 sgo:sdDataset articles
136 rdf:type schema:ScholarlyArticle
137 N047e29ba9ea44ffda0e9d5baa3e6b507 rdf:first sg:person.0673774654.56
138 rdf:rest N75fa7c8458e94775808ab531cb7e5526
139 N191658f030244f8ba1e4db33d1213e89 schema:volumeNumber 21
140 rdf:type schema:PublicationVolume
141 N23cfdc79d3584c79bd045ad884bfe5c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Magnetic Resonance Imaging
143 rdf:type schema:DefinedTerm
144 N27f3cd26c70748e6b8b38874ec681645 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Humans
146 rdf:type schema:DefinedTerm
147 N2bd8a041291e4670bacee7c134d546a6 rdf:first sg:person.01025022257.04
148 rdf:rest rdf:nil
149 N528e63e100994eddbf89e6343e536cb6 schema:name Springer Nature - SN SciGraph project
150 rdf:type schema:Organization
151 N5a017c48760d441fb74f14b5bc488928 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Middle Aged
153 rdf:type schema:DefinedTerm
154 N5d5c7c9f4faf475592b01efb214cadaf rdf:first sg:person.01011105227.42
155 rdf:rest N2bd8a041291e4670bacee7c134d546a6
156 N66d0015d9b0d4454a1beae33148d53bf schema:issueNumber 1
157 rdf:type schema:PublicationIssue
158 N755afd0b444d45729834163dfdadf600 rdf:first sg:person.01056105637.26
159 rdf:rest N5d5c7c9f4faf475592b01efb214cadaf
160 N75fa7c8458e94775808ab531cb7e5526 rdf:first sg:person.0722327110.33
161 rdf:rest N755afd0b444d45729834163dfdadf600
162 N7775e49e6de9412a9e9c216e7987ac97 schema:name doi
163 schema:value 10.1186/s12891-020-03231-3
164 rdf:type schema:PropertyValue
165 N7940ddcd143a4713a0c0e6fab9ad4c3c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Radiography
167 rdf:type schema:DefinedTerm
168 N7cdd2c2282544d7681c15e8efb77c5d5 schema:name pubmed_id
169 schema:value 32252731
170 rdf:type schema:PropertyValue
171 N7d1d243a7e364eb8bcc5a3e88fa6dba2 rdf:first sg:person.014154544361.87
172 rdf:rest N047e29ba9ea44ffda0e9d5baa3e6b507
173 Na81043ecc45a4cd49de0736133f38ba6 schema:name dimensions_id
174 schema:value pub.1126175454
175 rdf:type schema:PropertyValue
176 Nad44991f70ce4bf0a0badfdbb5693547 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Male
178 rdf:type schema:DefinedTerm
179 Nba4ee61f470942fbbc0fe7f946063024 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Pain Measurement
181 rdf:type schema:DefinedTerm
182 Nc36b2576638c4adfa2888f8fe8f8e52e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Adipose Tissue
184 rdf:type schema:DefinedTerm
185 Nc6c4ebd7e642471581fe425be0167cbb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Female
187 rdf:type schema:DefinedTerm
188 Nc7f50d4827924f7bb91a2a6fd85bde94 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Treatment Outcome
190 rdf:type schema:DefinedTerm
191 Ncb41df29eafc49ff920f3f09718fb618 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Injections, Intra-Articular
193 rdf:type schema:DefinedTerm
194 Nce958d6fcce24752b28c6f036395680d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Osteoarthritis, Knee
196 rdf:type schema:DefinedTerm
197 Ncf1706a27d914cdb8a7e0090e4a052dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
198 schema:name Mesenchymal Stem Cell Transplantation
199 rdf:type schema:DefinedTerm
200 Ne11b406276f14fbeb782ece5122e7475 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
201 schema:name Knee Joint
202 rdf:type schema:DefinedTerm
203 Nedc611b29fdd40ee989895f867016ea4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
204 schema:name Mesenchymal Stem Cells
205 rdf:type schema:DefinedTerm
206 Nfc3df015565444dba32d2df9d9a2c98e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
207 schema:name Range of Motion, Articular
208 rdf:type schema:DefinedTerm
209 Nfd84e252426c404e82a0b9220ba71efb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
210 schema:name Aged
211 rdf:type schema:DefinedTerm
212 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
213 schema:name Medical and Health Sciences
214 rdf:type schema:DefinedTerm
215 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
216 schema:name Clinical Sciences
217 rdf:type schema:DefinedTerm
218 sg:journal.1024957 schema:issn 1471-2474
219 schema:name BMC Musculoskeletal Disorders
220 schema:publisher Springer Nature
221 rdf:type schema:Periodical
222 sg:person.01011105227.42 schema:affiliation grid-institutes:None
223 schema:familyName Iwaguro
224 schema:givenName Hideki
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011105227.42
226 rdf:type schema:Person
227 sg:person.01025022257.04 schema:affiliation grid-institutes:grid.31432.37
228 schema:familyName Kuroda
229 schema:givenName Ryosuke
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025022257.04
231 rdf:type schema:Person
232 sg:person.01056105637.26 schema:affiliation grid-institutes:grid.31432.37
233 schema:familyName Matsushita
234 schema:givenName Takehiko
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056105637.26
236 rdf:type schema:Person
237 sg:person.014154544361.87 schema:affiliation grid-institutes:None
238 schema:familyName Tsubosaka
239 schema:givenName Masanori
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014154544361.87
241 rdf:type schema:Person
242 sg:person.0673774654.56 schema:affiliation grid-institutes:grid.31432.37
243 schema:familyName Matsumoto
244 schema:givenName Tomoyuki
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673774654.56
246 rdf:type schema:Person
247 sg:person.0722327110.33 schema:affiliation grid-institutes:None
248 schema:familyName Sobajima
249 schema:givenName Satoshi
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722327110.33
251 rdf:type schema:Person
252 sg:pub.10.1007/s00264-018-4099-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106150032
253 https://doi.org/10.1007/s00264-018-4099-0
254 rdf:type schema:CreativeWork
255 sg:pub.10.3758/brm.41.4.1149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019543365
256 https://doi.org/10.3758/brm.41.4.1149
257 rdf:type schema:CreativeWork
258 grid-institutes:None schema:alternateName Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan
259 schema:name Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
260 Department of Orthopaedic Surgery, Sobajima Clinic, 2-2-6, Aramotokita, Higashiosaka, Osaka, 577-0011 Japan
261 rdf:type schema:Organization
262 grid-institutes:grid.31432.37 schema:alternateName Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
263 schema:name Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
264 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...