Hip preserving surgery with concentrated autologous bone marrow aspirate transplantation for the treatment of asymptomatic osteonecrosis of the femoral head: ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-07-06

AUTHORS

Yohei Tomaru, Tomokazu Yoshioka, Hisashi Sugaya, Katsuya Aoto, Hiroshi Wada, Hiroshi Akaogi, Masashi Yamazaki, Hajime Mishima

ABSTRACT

BackgroundWe had previously established concentrated autologous bone marrow aspirate transplantation (CABMAT), a one-step, low-invasive, joint-preserving surgical technique for treating osteonecrosis of the femoral head (ONFH). The present study aimed to evaluate the effects of CABMAT as a hip preserving surgical approach, preventing femoral head collapse in asymptomatic ONFH.MethodsIn total, 222 patients (341 hips) with ONFH were treated with CABMAT between April 2003 and March 2013. Based on magnetic resonance imaging, we determined that 119 of these patients had bilateral asymptomatic ONFH (238 hips), and 38 further patients had unilateral asymptomatic ONFH (38 hips). In this series, we retrospectively examined 31 hips in 31 patients with unilateral asymptomatic ONFH treated surgically between 2003 and 2012 and followed up for more than 2 years. Clinical and radiological evaluation were performed immediately before the procedure and at the final follow-up. The two-year follow-up rate among patients with unilateral ONFH was 82% (31/38). Therefore, the present study included 31 patients (19 males and 12 females), with a mean age and follow-up period of 40 and 5.8 years, respectively. Of the 31 asymptomatic hips, 5, 6, 10, and 10 had osteonecrosis of types A, B, C1, and C2, respectively. The diagnosis, classification, and staging of ONFH were based on the 2001 Japanese Orthopaedic Association (JOA) classification.ResultsSecondary collapse of the femoral head was observed in 6/10 hips and 5/10 hips with osteonecrosis of types C1 and C2, respectively. Total hip arthroplasty was performed in 9.6% of patients (3/31 hips), at an average of 33 months after surgery. Clinical symptoms improved after surgery, and the secondary collapse rate at a mean of 5.8 years after CABMAT was lower than that reported in several previous studies on the natural course of asymptomatic ONFH.ConclusionsEarly diagnosis of ONFH (i.e., before femoral head collapse) and early intervention with CABMAT could improve the clinical outcome of corticosteroid and alcohol-induced ONFH. More... »

PAGES

292

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12891-017-1652-8

DOI

http://dx.doi.org/10.1186/s12891-017-1652-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1090365435

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28683795


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arthroplasty, Replacement, Hip", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Marrow Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Femur Head Necrosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Autologous", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomaru", 
        "givenName": "Yohei", 
        "id": "sg:person.01246000361.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246000361.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshioka", 
        "givenName": "Tomokazu", 
        "id": "sg:person.01222167317.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222167317.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sugaya", 
        "givenName": "Hisashi", 
        "id": "sg:person.01227541715.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227541715.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aoto", 
        "givenName": "Katsuya", 
        "id": "sg:person.0613011617.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613011617.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wada", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01045443347.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045443347.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akaogi", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01330400776.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330400776.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamazaki", 
        "givenName": "Masashi", 
        "id": "sg:person.01240750061.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240750061.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan", 
          "id": "http://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mishima", 
        "givenName": "Hajime", 
        "id": "sg:person.0636756147.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636756147.02"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11999-010-1292-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032132237", 
          "https://doi.org/10.1007/s11999-010-1292-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00264-010-1009-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007643909", 
          "https://doi.org/10.1007/s00264-010-1009-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00264-010-1048-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036011489", 
          "https://doi.org/10.1007/s00264-010-1048-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s007760200108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011171374", 
          "https://doi.org/10.1007/s007760200108"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-07-06", 
    "datePublishedReg": "2017-07-06", 
    "description": "BackgroundWe had previously established concentrated autologous bone marrow aspirate transplantation (CABMAT), a one-step, low-invasive, joint-preserving surgical technique for treating osteonecrosis of the femoral head (ONFH). The present study aimed to evaluate the effects of CABMAT as a hip preserving surgical approach, preventing femoral head collapse in asymptomatic ONFH.MethodsIn total, 222 patients (341 hips) with ONFH were treated with CABMAT between April 2003 and March 2013. Based on magnetic resonance imaging, we determined that 119 of these patients had bilateral asymptomatic ONFH (238 hips), and 38 further patients had unilateral asymptomatic ONFH (38 hips). In this series, we retrospectively examined 31 hips in 31 patients with unilateral asymptomatic ONFH treated surgically between 2003 and 2012 and followed up for more than 2\u00a0years. Clinical and radiological evaluation were performed immediately before the procedure and at the final follow-up. The two-year follow-up rate among patients with unilateral ONFH was 82% (31/38). Therefore, the present study included 31 patients (19 males and 12 females), with a mean age and follow-up period of 40 and 5.8\u00a0years, respectively. Of the 31 asymptomatic hips, 5, 6, 10, and 10 had osteonecrosis of types A, B, C1, and C2, respectively. The diagnosis, classification, and staging of ONFH were based on the 2001 Japanese Orthopaedic Association (JOA) classification.ResultsSecondary collapse of the femoral head was observed in 6/10 hips and 5/10 hips with osteonecrosis of types C1 and C2, respectively. Total hip arthroplasty was performed in 9.6% of patients (3/31 hips), at an average of 33\u00a0months after surgery. Clinical symptoms improved after surgery, and the secondary collapse rate at a mean of 5.8\u00a0years after CABMAT was lower than that reported in several previous studies on the natural course of asymptomatic ONFH.ConclusionsEarly diagnosis of ONFH (i.e., before femoral head collapse) and early intervention with CABMAT could improve the clinical outcome of corticosteroid and alcohol-induced ONFH.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12891-017-1652-8", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024957", 
        "issn": [
          "1471-2474"
        ], 
        "name": "BMC Musculoskeletal Disorders", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "keywords": [
      "concentrated autologous bone marrow aspirate transplantation", 
      "femoral head", 
      "Japanese Orthopaedic Association classification", 
      "femoral head collapse", 
      "alcohol-induced ONFH", 
      "two-year follow", 
      "total hip arthroplasty", 
      "diagnosis of ONFH", 
      "magnetic resonance imaging", 
      "unilateral ONFH", 
      "asymptomatic osteonecrosis", 
      "radiological outcomes", 
      "further patients", 
      "radiological evaluation", 
      "retrospective review", 
      "head collapse", 
      "clinical outcomes", 
      "clinical symptoms", 
      "present study", 
      "surgical approach", 
      "mean age", 
      "asymptomatic hips", 
      "natural course", 
      "Association classification", 
      "surgical technique", 
      "MethodsIn total", 
      "hip arthroplasty", 
      "patients", 
      "ONFH", 
      "osteonecrosis", 
      "early intervention", 
      "resonance imaging", 
      "hip", 
      "surgery", 
      "type C1", 
      "transplantation", 
      "type A", 
      "diagnosis", 
      "outcomes", 
      "years", 
      "head", 
      "corticosteroids", 
      "previous studies", 
      "BackgroundWe", 
      "arthroplasty", 
      "follow", 
      "symptoms", 
      "staging", 
      "months", 
      "study", 
      "age", 
      "intervention", 
      "treatment", 
      "total", 
      "rate", 
      "imaging", 
      "review", 
      "course", 
      "period", 
      "evaluation", 
      "C1", 
      "classification", 
      "procedure", 
      "effect", 
      "average", 
      "C2", 
      "collapse rate", 
      "series", 
      "means", 
      "collapse", 
      "technique", 
      "approach", 
      "one-step"
    ], 
    "name": "Hip preserving surgery with concentrated autologous bone marrow aspirate transplantation for the treatment of asymptomatic osteonecrosis of the femoral head: retrospective review of clinical and radiological outcomes at 6 years postoperatively", 
    "pagination": "292", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1090365435"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12891-017-1652-8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28683795"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12891-017-1652-8", 
      "https://app.dimensions.ai/details/publication/pub.1090365435"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-08-04T17:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_732.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12891-017-1652-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12891-017-1652-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12891-017-1652-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12891-017-1652-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12891-017-1652-8'


 

This table displays all metadata directly associated to this object as RDF triples.

260 TRIPLES      21 PREDICATES      117 URIs      105 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12891-017-1652-8 schema:about N1d71fd28c90344f0859f72533551dba0
2 N22201d523bfe438790ef4c37e8abdb50
3 N236e26233d9d478a803b4780c0abcac3
4 N50d391845d0940129f9539c37b3f6a69
5 N557969f81eea4c5a9e10e9e08a655e97
6 N5f1912bd944541f5abdb2362fa259415
7 N82a6c04fd0e1407a83321d8f1e24dd63
8 N9009a2d1be8642b4a10497f0920e4d1f
9 Nabe30157d6f84501859b3b01a16f317b
10 Nac80e881e73d47c7b0e82bbfe05dca2d
11 Nbcc2042a06e94b37bb60b0ce7f4d4f93
12 Nc595cb3a01244ff392b2889d87fe4b0e
13 Nd145820b35c6475d806b176af2c7f8e8
14 Nd3a2dc2fc2144584b4ecee107295719c
15 Ndff36d2ac23c431d8c39f5f3ac51cdc7
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author Nb366751ac7c84f77b47dd6c7e94d34f1
19 schema:citation sg:pub.10.1007/s00264-010-1009-5
20 sg:pub.10.1007/s00264-010-1048-y
21 sg:pub.10.1007/s007760200108
22 sg:pub.10.1007/s11999-010-1292-x
23 schema:datePublished 2017-07-06
24 schema:datePublishedReg 2017-07-06
25 schema:description BackgroundWe had previously established concentrated autologous bone marrow aspirate transplantation (CABMAT), a one-step, low-invasive, joint-preserving surgical technique for treating osteonecrosis of the femoral head (ONFH). The present study aimed to evaluate the effects of CABMAT as a hip preserving surgical approach, preventing femoral head collapse in asymptomatic ONFH.MethodsIn total, 222 patients (341 hips) with ONFH were treated with CABMAT between April 2003 and March 2013. Based on magnetic resonance imaging, we determined that 119 of these patients had bilateral asymptomatic ONFH (238 hips), and 38 further patients had unilateral asymptomatic ONFH (38 hips). In this series, we retrospectively examined 31 hips in 31 patients with unilateral asymptomatic ONFH treated surgically between 2003 and 2012 and followed up for more than 2 years. Clinical and radiological evaluation were performed immediately before the procedure and at the final follow-up. The two-year follow-up rate among patients with unilateral ONFH was 82% (31/38). Therefore, the present study included 31 patients (19 males and 12 females), with a mean age and follow-up period of 40 and 5.8 years, respectively. Of the 31 asymptomatic hips, 5, 6, 10, and 10 had osteonecrosis of types A, B, C1, and C2, respectively. The diagnosis, classification, and staging of ONFH were based on the 2001 Japanese Orthopaedic Association (JOA) classification.ResultsSecondary collapse of the femoral head was observed in 6/10 hips and 5/10 hips with osteonecrosis of types C1 and C2, respectively. Total hip arthroplasty was performed in 9.6% of patients (3/31 hips), at an average of 33 months after surgery. Clinical symptoms improved after surgery, and the secondary collapse rate at a mean of 5.8 years after CABMAT was lower than that reported in several previous studies on the natural course of asymptomatic ONFH.ConclusionsEarly diagnosis of ONFH (i.e., before femoral head collapse) and early intervention with CABMAT could improve the clinical outcome of corticosteroid and alcohol-induced ONFH.
26 schema:genre article
27 schema:isAccessibleForFree true
28 schema:isPartOf N0d5ad893c7db4738816f376d32c3d7b1
29 Nb34d55c653f94bc3a2895f6240548baa
30 sg:journal.1024957
31 schema:keywords Association classification
32 BackgroundWe
33 C1
34 C2
35 Japanese Orthopaedic Association classification
36 MethodsIn total
37 ONFH
38 age
39 alcohol-induced ONFH
40 approach
41 arthroplasty
42 asymptomatic hips
43 asymptomatic osteonecrosis
44 average
45 classification
46 clinical outcomes
47 clinical symptoms
48 collapse
49 collapse rate
50 concentrated autologous bone marrow aspirate transplantation
51 corticosteroids
52 course
53 diagnosis
54 diagnosis of ONFH
55 early intervention
56 effect
57 evaluation
58 femoral head
59 femoral head collapse
60 follow
61 further patients
62 head
63 head collapse
64 hip
65 hip arthroplasty
66 imaging
67 intervention
68 magnetic resonance imaging
69 mean age
70 means
71 months
72 natural course
73 one-step
74 osteonecrosis
75 outcomes
76 patients
77 period
78 present study
79 previous studies
80 procedure
81 radiological evaluation
82 radiological outcomes
83 rate
84 resonance imaging
85 retrospective review
86 review
87 series
88 staging
89 study
90 surgery
91 surgical approach
92 surgical technique
93 symptoms
94 technique
95 total
96 total hip arthroplasty
97 transplantation
98 treatment
99 two-year follow
100 type A
101 type C1
102 unilateral ONFH
103 years
104 schema:name Hip preserving surgery with concentrated autologous bone marrow aspirate transplantation for the treatment of asymptomatic osteonecrosis of the femoral head: retrospective review of clinical and radiological outcomes at 6 years postoperatively
105 schema:pagination 292
106 schema:productId N2b43f1c9aec9497f964a3422739bdd7b
107 Nc08d37bdf43f48fc9b0ce1d482534d3e
108 Nc261a1ee18e848498b40a4eaba032d4c
109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090365435
110 https://doi.org/10.1186/s12891-017-1652-8
111 schema:sdDatePublished 2022-08-04T17:04
112 schema:sdLicense https://scigraph.springernature.com/explorer/license/
113 schema:sdPublisher Nc706463bd2f940ffb8e6cdd48d3e4a3e
114 schema:url https://doi.org/10.1186/s12891-017-1652-8
115 sgo:license sg:explorer/license/
116 sgo:sdDataset articles
117 rdf:type schema:ScholarlyArticle
118 N0d5ad893c7db4738816f376d32c3d7b1 schema:issueNumber 1
119 rdf:type schema:PublicationIssue
120 N1b48db6b7df34c898fda2be44313beb9 rdf:first sg:person.01330400776.19
121 rdf:rest N800bfe61e0b444f8b5da7a07f0a2548c
122 N1d71fd28c90344f0859f72533551dba0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Time Factors
124 rdf:type schema:DefinedTerm
125 N22201d523bfe438790ef4c37e8abdb50 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Middle Aged
127 rdf:type schema:DefinedTerm
128 N236e26233d9d478a803b4780c0abcac3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Treatment Outcome
130 rdf:type schema:DefinedTerm
131 N29fa737164474662802d1d1974dc329e rdf:first sg:person.0636756147.02
132 rdf:rest rdf:nil
133 N2b43f1c9aec9497f964a3422739bdd7b schema:name doi
134 schema:value 10.1186/s12891-017-1652-8
135 rdf:type schema:PropertyValue
136 N50d391845d0940129f9539c37b3f6a69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Magnetic Resonance Imaging
138 rdf:type schema:DefinedTerm
139 N557969f81eea4c5a9e10e9e08a655e97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Adult
141 rdf:type schema:DefinedTerm
142 N5f1912bd944541f5abdb2362fa259415 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Follow-Up Studies
144 rdf:type schema:DefinedTerm
145 N800bfe61e0b444f8b5da7a07f0a2548c rdf:first sg:person.01240750061.11
146 rdf:rest N29fa737164474662802d1d1974dc329e
147 N82a6c04fd0e1407a83321d8f1e24dd63 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Female
149 rdf:type schema:DefinedTerm
150 N8f0d126067894b40ac7a0ea2ac7b0f00 rdf:first sg:person.01045443347.53
151 rdf:rest N1b48db6b7df34c898fda2be44313beb9
152 N9009a2d1be8642b4a10497f0920e4d1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Retrospective Studies
154 rdf:type schema:DefinedTerm
155 Nabe30157d6f84501859b3b01a16f317b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Humans
157 rdf:type schema:DefinedTerm
158 Nac80e881e73d47c7b0e82bbfe05dca2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Male
160 rdf:type schema:DefinedTerm
161 Nb34d55c653f94bc3a2895f6240548baa schema:volumeNumber 18
162 rdf:type schema:PublicationVolume
163 Nb366751ac7c84f77b47dd6c7e94d34f1 rdf:first sg:person.01246000361.87
164 rdf:rest Nf52c684f77ed4228906ee6b89c607eac
165 Nb69f89f4ce134f20b3aef286f76207a6 rdf:first sg:person.0613011617.01
166 rdf:rest N8f0d126067894b40ac7a0ea2ac7b0f00
167 Nbcc2042a06e94b37bb60b0ce7f4d4f93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Transplantation, Autologous
169 rdf:type schema:DefinedTerm
170 Nc08d37bdf43f48fc9b0ce1d482534d3e schema:name dimensions_id
171 schema:value pub.1090365435
172 rdf:type schema:PropertyValue
173 Nc261a1ee18e848498b40a4eaba032d4c schema:name pubmed_id
174 schema:value 28683795
175 rdf:type schema:PropertyValue
176 Nc595cb3a01244ff392b2889d87fe4b0e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Femur Head Necrosis
178 rdf:type schema:DefinedTerm
179 Nc706463bd2f940ffb8e6cdd48d3e4a3e schema:name Springer Nature - SN SciGraph project
180 rdf:type schema:Organization
181 Nd145820b35c6475d806b176af2c7f8e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Arthroplasty, Replacement, Hip
183 rdf:type schema:DefinedTerm
184 Nd3a2dc2fc2144584b4ecee107295719c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Bone Marrow Transplantation
186 rdf:type schema:DefinedTerm
187 Nd619cbcaebf0443fbc1a5294c85eabd0 rdf:first sg:person.01227541715.23
188 rdf:rest Nb69f89f4ce134f20b3aef286f76207a6
189 Ndff36d2ac23c431d8c39f5f3ac51cdc7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Aged
191 rdf:type schema:DefinedTerm
192 Nf52c684f77ed4228906ee6b89c607eac rdf:first sg:person.01222167317.14
193 rdf:rest Nd619cbcaebf0443fbc1a5294c85eabd0
194 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
195 schema:name Medical and Health Sciences
196 rdf:type schema:DefinedTerm
197 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
198 schema:name Clinical Sciences
199 rdf:type schema:DefinedTerm
200 sg:journal.1024957 schema:issn 1471-2474
201 schema:name BMC Musculoskeletal Disorders
202 schema:publisher Springer Nature
203 rdf:type schema:Periodical
204 sg:person.01045443347.53 schema:affiliation grid-institutes:grid.20515.33
205 schema:familyName Wada
206 schema:givenName Hiroshi
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045443347.53
208 rdf:type schema:Person
209 sg:person.01222167317.14 schema:affiliation grid-institutes:grid.20515.33
210 schema:familyName Yoshioka
211 schema:givenName Tomokazu
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222167317.14
213 rdf:type schema:Person
214 sg:person.01227541715.23 schema:affiliation grid-institutes:grid.20515.33
215 schema:familyName Sugaya
216 schema:givenName Hisashi
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227541715.23
218 rdf:type schema:Person
219 sg:person.01240750061.11 schema:affiliation grid-institutes:grid.20515.33
220 schema:familyName Yamazaki
221 schema:givenName Masashi
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01240750061.11
223 rdf:type schema:Person
224 sg:person.01246000361.87 schema:affiliation grid-institutes:grid.20515.33
225 schema:familyName Tomaru
226 schema:givenName Yohei
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246000361.87
228 rdf:type schema:Person
229 sg:person.01330400776.19 schema:affiliation grid-institutes:grid.20515.33
230 schema:familyName Akaogi
231 schema:givenName Hiroshi
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330400776.19
233 rdf:type schema:Person
234 sg:person.0613011617.01 schema:affiliation grid-institutes:grid.20515.33
235 schema:familyName Aoto
236 schema:givenName Katsuya
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613011617.01
238 rdf:type schema:Person
239 sg:person.0636756147.02 schema:affiliation grid-institutes:grid.20515.33
240 schema:familyName Mishima
241 schema:givenName Hajime
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636756147.02
243 rdf:type schema:Person
244 sg:pub.10.1007/s00264-010-1009-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007643909
245 https://doi.org/10.1007/s00264-010-1009-5
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/s00264-010-1048-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1036011489
248 https://doi.org/10.1007/s00264-010-1048-y
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/s007760200108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011171374
251 https://doi.org/10.1007/s007760200108
252 rdf:type schema:CreativeWork
253 sg:pub.10.1007/s11999-010-1292-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032132237
254 https://doi.org/10.1007/s11999-010-1292-x
255 rdf:type schema:CreativeWork
256 grid-institutes:grid.20515.33 schema:alternateName Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan
257 Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan
258 schema:name Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan
259 Division of Regenerative Medicine for Musculoskeletal System, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Ibaraki, Japan
260 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...