A cohort study of 4,190 patients treated with low-intensity pulsed ultrasound (LIPUS): findings in the elderly versus all patients View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-03-01

AUTHORS

Robert Zura, Samir Mehta, Gregory J Della Rocca, John Jones, R Grant Steen

ABSTRACT

BackgroundPatient age is one of many potential risk factors for fracture nonunion. Our hypothesis is that older patients (≥60) with fracture risk factors treated with low-intensity pulsed ultrasound (LIPUS) have similar heal rate (HR) to the population as a whole. We evaluate the impact of age in conjunction with other risk factors on HR in LIPUS-treated patients with fresh fracture (≤90 days old).MethodsThe Exogen Bone Healing System is a LIPUS device approved in 1994 to accelerate healing of fresh fracture. After approval, the FDA required a Post-Market Registry to assess performance. Patient data collected from October 1994 until October 1998 were individually reviewed and validated by a registered nurse. Four distinct data elements were required to report a patient: date fracture occurred; date treatment began; date treatment ended; and a dichotomous outcome of healed v. failed, by clinical and radiological criteria. Data were used to calculate two derived variables; days to treatment (DTT) and days on treatment (DOT). Every validated fresh fracture patient with DTT, DOT, and outcome is reported.ResultsThe validated registry had 5,765 patients with fresh fracture; 73% (N = 4,190) are reported, while 13% of patients were lost to follow-up, 11% withdrew or were non-compliant, and 3% died or are missing outcome. Among treatment-compliant patients, HR was 96.2%. Logistic estimates of the odds ratio for healing are equivalent for patients age 30 to 79 years and all age cohorts had a HR > 94%. Open fracture, current smoking, diabetes, vascular insufficiency, osteoporosis, cancer, rheumatoid arthritis, and prescription NSAIDs all reduced HR, but older patients (≥60) had similar HRs to the population as a whole. DTT was significantly shorter for patients who healed (p < 0.0001).ConclusionsComorbid conditions in conjunction with aging can reduce fracture HR. Patients with fracture who used LIPUS had a 96% HR, whereas the expected HR averages 93%. Time to treatment was significantly shorter among patients who healed (p < 0.0001), suggesting that it is beneficial to begin LIPUS treatment early. Older patients (≥60) with fracture risk factors treated with LIPUS exhibit similar heal rates to the population as a whole. More... »

PAGES

45

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12891-015-0498-1

DOI

http://dx.doi.org/10.1186/s12891-015-0498-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013519804

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25886761


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Age Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Comorbidity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fracture Healing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fractures, Bone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Logistic Models", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Odds Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Product Surveillance, Postmarketing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Registries", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time-to-Treatment", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ultrasonic Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA", 
          "id": "http://www.grid.ac/institutes/grid.189509.c", 
          "name": [
            "Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zura", 
        "givenName": "Robert", 
        "id": "sg:person.01254111355.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254111355.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA", 
          "id": "http://www.grid.ac/institutes/grid.411115.1", 
          "name": [
            "Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mehta", 
        "givenName": "Samir", 
        "id": "sg:person.01232265321.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232265321.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA", 
          "id": "http://www.grid.ac/institutes/grid.134936.a", 
          "name": [
            "Department of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rocca", 
        "givenName": "Gregory J Della", 
        "id": "sg:person.014034124411.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014034124411.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Affairs, Bioventus LLC, Durham, NC, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Medical Affairs, Bioventus LLC, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jones", 
        "givenName": "John", 
        "id": "sg:person.0577123715.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577123715.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Affairs, Bioventus LLC, Durham, NC, USA", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Medical Affairs, Bioventus LLC, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Steen", 
        "givenName": "R Grant", 
        "id": "sg:person.0650346750.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650346750.97"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/pl00021234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074583283", 
          "https://doi.org/10.1007/pl00021234"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00223-013-9785-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049576656", 
          "https://doi.org/10.1007/s00223-013-9785-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11999-009-1162-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014535631", 
          "https://doi.org/10.1007/s11999-009-1162-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02390832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033546805", 
          "https://doi.org/10.1007/bf02390832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-010-1335-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005086303", 
          "https://doi.org/10.1007/s00167-010-1335-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00590-011-0936-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008006063", 
          "https://doi.org/10.1007/s00590-011-0936-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00402-012-1631-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020719098", 
          "https://doi.org/10.1007/s00402-012-1631-3"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-03-01", 
    "datePublishedReg": "2015-03-01", 
    "description": "BackgroundPatient age is one of many potential risk factors for fracture nonunion. Our hypothesis is that older patients (\u226560) with fracture risk factors treated with low-intensity pulsed ultrasound (LIPUS) have similar heal rate (HR) to the population as a whole. We evaluate the impact of age in conjunction with other risk factors on HR in LIPUS-treated patients with fresh fracture (\u226490\u00a0days old).MethodsThe Exogen Bone Healing System is a LIPUS device approved in 1994 to accelerate healing of fresh fracture. After approval, the FDA required a Post-Market Registry to assess performance. Patient data collected from October 1994 until October 1998 were individually reviewed and validated by a registered nurse. Four distinct data elements were required to report a patient: date fracture occurred; date treatment began; date treatment ended; and a dichotomous outcome of healed v. failed, by clinical and radiological criteria. Data were used to calculate two derived variables; days to treatment (DTT) and days on treatment (DOT). Every validated fresh fracture patient with DTT, DOT, and outcome is reported.ResultsThe validated registry had 5,765 patients with fresh fracture; 73% (N\u2009=\u20094,190) are reported, while 13% of patients were lost to follow-up, 11% withdrew or were non-compliant, and 3% died or are missing outcome. Among treatment-compliant patients, HR was 96.2%. Logistic estimates of the odds ratio for healing are equivalent for patients age 30 to 79\u00a0years and all age cohorts had a HR\u2009>\u200994%. Open fracture, current smoking, diabetes, vascular insufficiency, osteoporosis, cancer, rheumatoid arthritis, and prescription NSAIDs all reduced HR, but older patients (\u226560) had similar HRs to the population as a whole. DTT was significantly shorter for patients who healed (p\u2009<\u20090.0001).ConclusionsComorbid conditions in conjunction with aging can reduce fracture HR. Patients with fracture who used LIPUS had a 96% HR, whereas the expected HR averages 93%. Time to treatment was significantly shorter among patients who healed (p\u2009<\u20090.0001), suggesting that it is beneficial to begin LIPUS treatment early. Older patients (\u226560) with fracture risk factors treated with LIPUS exhibit similar heal rates to the population as a whole.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12891-015-0498-1", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024957", 
        "issn": [
          "1471-2474"
        ], 
        "name": "BMC Musculoskeletal Disorders", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "keywords": [
      "fracture risk factors", 
      "risk factors", 
      "older patients", 
      "heal rate", 
      "fresh fractures", 
      "treatment-compliant patients", 
      "patients age 30", 
      "potential risk factors", 
      "post-market registry", 
      "impact of age", 
      "prescription NSAIDs", 
      "fracture patients", 
      "current smoking", 
      "cohort study", 
      "vascular insufficiency", 
      "rheumatoid arthritis", 
      "fracture nonunion", 
      "radiological criteria", 
      "odds ratio", 
      "patients", 
      "dichotomous outcomes", 
      "LIPUS device", 
      "LIPUS treatment", 
      "age 30", 
      "Registered Nurses", 
      "date fractures", 
      "patient data", 
      "treatment", 
      "registry", 
      "outcomes", 
      "date treatment", 
      "distinct data elements", 
      "age cohorts", 
      "fractures", 
      "ultrasound", 
      "healing", 
      "age", 
      "population", 
      "days", 
      "arthritis", 
      "nonunion", 
      "smoking", 
      "NSAIDs", 
      "diabetes", 
      "osteoporosis", 
      "factors", 
      "cohort", 
      "insufficiency", 
      "cancer", 
      "nurses", 
      "LIPUS", 
      "FDA", 
      "data elements", 
      "healing systems", 
      "approval", 
      "logistic estimates", 
      "rate", 
      "DTT", 
      "years", 
      "findings", 
      "data", 
      "criteria", 
      "study", 
      "conjunction", 
      "hypothesis", 
      "variables", 
      "ratio", 
      "impact", 
      "time", 
      "whole", 
      "conditions", 
      "estimates", 
      "system", 
      "devices", 
      "elements", 
      "performance", 
      "dots"
    ], 
    "name": "A cohort study of 4,190 patients treated with low-intensity pulsed ultrasound (LIPUS): findings in the elderly versus all patients", 
    "pagination": "45", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013519804"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12891-015-0498-1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25886761"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12891-015-0498-1", 
      "https://app.dimensions.ai/details/publication/pub.1013519804"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_680.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12891-015-0498-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12891-015-0498-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12891-015-0498-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12891-015-0498-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12891-015-0498-1'


 

This table displays all metadata directly associated to this object as RDF triples.

287 TRIPLES      22 PREDICATES      131 URIs      116 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12891-015-0498-1 schema:about N0840e82de8734867aa9bbeac69dacb5f
2 N0a6e541360cd4d508d95cf5efbe6beff
3 N21bd04bbe8534df5be381d4637055def
4 N39c614413ee944cf89806de69ecbd27f
5 N3e00a63a6ee44c93850da27a1d2f9c95
6 N3e5430898794460b9d2e8ae5d0a43098
7 N433542df5a1a4b2f8bb174027eb90b6f
8 N51b8032b42a4487fa23d2f8f8e9cf5e1
9 N5ccabd6f91034806b353a79a67b5cd84
10 N6e1c6a2c2b7d4a8784d41099e07a8854
11 N88615c6f7e194de3986c780bccb28e00
12 N91577d50d7a44e03801cdce77f84fd42
13 N9aed9ce3be2f4a759eb001b9fccd8b10
14 Nb9ab2a8253f442eb933779f29a067dd8
15 Nb9b60e2013b04f55914a535b2ff75a91
16 Nd900fb96c95644f487311afc7667da92
17 Nd9c3eac10dad42288e23c841d54cc879
18 Ndc63bfa2aaa3494dac1578aae69ca111
19 Nebafd2d0bfef42baa26fabfc174af0a9
20 Nf5b351071e1a4a66994998ab0107749d
21 Nf7d7d3164e72491ab60275dafc0b12a7
22 anzsrc-for:11
23 anzsrc-for:1103
24 schema:author N266b9f3a6feb49e38017c1b1fbe78038
25 schema:citation sg:pub.10.1007/bf02390832
26 sg:pub.10.1007/pl00021234
27 sg:pub.10.1007/s00167-010-1335-6
28 sg:pub.10.1007/s00223-013-9785-8
29 sg:pub.10.1007/s00402-012-1631-3
30 sg:pub.10.1007/s00590-011-0936-1
31 sg:pub.10.1007/s11999-009-1162-6
32 schema:datePublished 2015-03-01
33 schema:datePublishedReg 2015-03-01
34 schema:description BackgroundPatient age is one of many potential risk factors for fracture nonunion. Our hypothesis is that older patients (≥60) with fracture risk factors treated with low-intensity pulsed ultrasound (LIPUS) have similar heal rate (HR) to the population as a whole. We evaluate the impact of age in conjunction with other risk factors on HR in LIPUS-treated patients with fresh fracture (≤90 days old).MethodsThe Exogen Bone Healing System is a LIPUS device approved in 1994 to accelerate healing of fresh fracture. After approval, the FDA required a Post-Market Registry to assess performance. Patient data collected from October 1994 until October 1998 were individually reviewed and validated by a registered nurse. Four distinct data elements were required to report a patient: date fracture occurred; date treatment began; date treatment ended; and a dichotomous outcome of healed v. failed, by clinical and radiological criteria. Data were used to calculate two derived variables; days to treatment (DTT) and days on treatment (DOT). Every validated fresh fracture patient with DTT, DOT, and outcome is reported.ResultsThe validated registry had 5,765 patients with fresh fracture; 73% (N = 4,190) are reported, while 13% of patients were lost to follow-up, 11% withdrew or were non-compliant, and 3% died or are missing outcome. Among treatment-compliant patients, HR was 96.2%. Logistic estimates of the odds ratio for healing are equivalent for patients age 30 to 79 years and all age cohorts had a HR > 94%. Open fracture, current smoking, diabetes, vascular insufficiency, osteoporosis, cancer, rheumatoid arthritis, and prescription NSAIDs all reduced HR, but older patients (≥60) had similar HRs to the population as a whole. DTT was significantly shorter for patients who healed (p < 0.0001).ConclusionsComorbid conditions in conjunction with aging can reduce fracture HR. Patients with fracture who used LIPUS had a 96% HR, whereas the expected HR averages 93%. Time to treatment was significantly shorter among patients who healed (p < 0.0001), suggesting that it is beneficial to begin LIPUS treatment early. Older patients (≥60) with fracture risk factors treated with LIPUS exhibit similar heal rates to the population as a whole.
35 schema:genre article
36 schema:inLanguage en
37 schema:isAccessibleForFree true
38 schema:isPartOf N54899a3e2cdf4b11a7bf24f67eef6fbb
39 N7e8870680dcc4f63907d903256d576bf
40 sg:journal.1024957
41 schema:keywords DTT
42 FDA
43 LIPUS
44 LIPUS device
45 LIPUS treatment
46 NSAIDs
47 Registered Nurses
48 age
49 age 30
50 age cohorts
51 approval
52 arthritis
53 cancer
54 cohort
55 cohort study
56 conditions
57 conjunction
58 criteria
59 current smoking
60 data
61 data elements
62 date fractures
63 date treatment
64 days
65 devices
66 diabetes
67 dichotomous outcomes
68 distinct data elements
69 dots
70 elements
71 estimates
72 factors
73 findings
74 fracture nonunion
75 fracture patients
76 fracture risk factors
77 fractures
78 fresh fractures
79 heal rate
80 healing
81 healing systems
82 hypothesis
83 impact
84 impact of age
85 insufficiency
86 logistic estimates
87 nonunion
88 nurses
89 odds ratio
90 older patients
91 osteoporosis
92 outcomes
93 patient data
94 patients
95 patients age 30
96 performance
97 population
98 post-market registry
99 potential risk factors
100 prescription NSAIDs
101 radiological criteria
102 rate
103 ratio
104 registry
105 rheumatoid arthritis
106 risk factors
107 smoking
108 study
109 system
110 time
111 treatment
112 treatment-compliant patients
113 ultrasound
114 variables
115 vascular insufficiency
116 whole
117 years
118 schema:name A cohort study of 4,190 patients treated with low-intensity pulsed ultrasound (LIPUS): findings in the elderly versus all patients
119 schema:pagination 45
120 schema:productId N0da242190cf54542a7b257989da7cac8
121 N88e724efe9624b73b220964722ee602c
122 Ne47527f1103d432cb07c43e1bf4cf0c4
123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013519804
124 https://doi.org/10.1186/s12891-015-0498-1
125 schema:sdDatePublished 2022-05-20T07:31
126 schema:sdLicense https://scigraph.springernature.com/explorer/license/
127 schema:sdPublisher N67bb2a87d63a4a42a9c1e82c08578b17
128 schema:url https://doi.org/10.1186/s12891-015-0498-1
129 sgo:license sg:explorer/license/
130 sgo:sdDataset articles
131 rdf:type schema:ScholarlyArticle
132 N0840e82de8734867aa9bbeac69dacb5f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Age Factors
134 rdf:type schema:DefinedTerm
135 N0a6e541360cd4d508d95cf5efbe6beff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Young Adult
137 rdf:type schema:DefinedTerm
138 N0da242190cf54542a7b257989da7cac8 schema:name dimensions_id
139 schema:value pub.1013519804
140 rdf:type schema:PropertyValue
141 N10228113063f45279e4e4a6cdf239151 rdf:first sg:person.0577123715.04
142 rdf:rest N9787a848bedf4bb794e35bee26881d0f
143 N21bd04bbe8534df5be381d4637055def schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Fracture Healing
145 rdf:type schema:DefinedTerm
146 N266b9f3a6feb49e38017c1b1fbe78038 rdf:first sg:person.01254111355.34
147 rdf:rest N5a6584fb03914ac0a2a531d83975852a
148 N39c614413ee944cf89806de69ecbd27f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Male
150 rdf:type schema:DefinedTerm
151 N3e00a63a6ee44c93850da27a1d2f9c95 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Risk Factors
153 rdf:type schema:DefinedTerm
154 N3e5430898794460b9d2e8ae5d0a43098 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Fractures, Bone
156 rdf:type schema:DefinedTerm
157 N433542df5a1a4b2f8bb174027eb90b6f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Humans
159 rdf:type schema:DefinedTerm
160 N51b8032b42a4487fa23d2f8f8e9cf5e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Time Factors
162 rdf:type schema:DefinedTerm
163 N54899a3e2cdf4b11a7bf24f67eef6fbb schema:volumeNumber 16
164 rdf:type schema:PublicationVolume
165 N5a6584fb03914ac0a2a531d83975852a rdf:first sg:person.01232265321.81
166 rdf:rest N613b3f7865cb4fc9b7e4789cce438be8
167 N5ccabd6f91034806b353a79a67b5cd84 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Time-to-Treatment
169 rdf:type schema:DefinedTerm
170 N613b3f7865cb4fc9b7e4789cce438be8 rdf:first sg:person.014034124411.30
171 rdf:rest N10228113063f45279e4e4a6cdf239151
172 N67bb2a87d63a4a42a9c1e82c08578b17 schema:name Springer Nature - SN SciGraph project
173 rdf:type schema:Organization
174 N6e1c6a2c2b7d4a8784d41099e07a8854 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Ultrasonic Therapy
176 rdf:type schema:DefinedTerm
177 N7e8870680dcc4f63907d903256d576bf schema:issueNumber 1
178 rdf:type schema:PublicationIssue
179 N88615c6f7e194de3986c780bccb28e00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Female
181 rdf:type schema:DefinedTerm
182 N88e724efe9624b73b220964722ee602c schema:name doi
183 schema:value 10.1186/s12891-015-0498-1
184 rdf:type schema:PropertyValue
185 N91577d50d7a44e03801cdce77f84fd42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Aged
187 rdf:type schema:DefinedTerm
188 N9787a848bedf4bb794e35bee26881d0f rdf:first sg:person.0650346750.97
189 rdf:rest rdf:nil
190 N9aed9ce3be2f4a759eb001b9fccd8b10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Aged, 80 and over
192 rdf:type schema:DefinedTerm
193 Nb9ab2a8253f442eb933779f29a067dd8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Adult
195 rdf:type schema:DefinedTerm
196 Nb9b60e2013b04f55914a535b2ff75a91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Odds Ratio
198 rdf:type schema:DefinedTerm
199 Nd900fb96c95644f487311afc7667da92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Comorbidity
201 rdf:type schema:DefinedTerm
202 Nd9c3eac10dad42288e23c841d54cc879 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Treatment Outcome
204 rdf:type schema:DefinedTerm
205 Ndc63bfa2aaa3494dac1578aae69ca111 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Product Surveillance, Postmarketing
207 rdf:type schema:DefinedTerm
208 Ne47527f1103d432cb07c43e1bf4cf0c4 schema:name pubmed_id
209 schema:value 25886761
210 rdf:type schema:PropertyValue
211 Nebafd2d0bfef42baa26fabfc174af0a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
212 schema:name Logistic Models
213 rdf:type schema:DefinedTerm
214 Nf5b351071e1a4a66994998ab0107749d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
215 schema:name Registries
216 rdf:type schema:DefinedTerm
217 Nf7d7d3164e72491ab60275dafc0b12a7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
218 schema:name Middle Aged
219 rdf:type schema:DefinedTerm
220 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
221 schema:name Medical and Health Sciences
222 rdf:type schema:DefinedTerm
223 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
224 schema:name Clinical Sciences
225 rdf:type schema:DefinedTerm
226 sg:journal.1024957 schema:issn 1471-2474
227 schema:name BMC Musculoskeletal Disorders
228 schema:publisher Springer Nature
229 rdf:type schema:Periodical
230 sg:person.01232265321.81 schema:affiliation grid-institutes:grid.411115.1
231 schema:familyName Mehta
232 schema:givenName Samir
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232265321.81
234 rdf:type schema:Person
235 sg:person.01254111355.34 schema:affiliation grid-institutes:grid.189509.c
236 schema:familyName Zura
237 schema:givenName Robert
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254111355.34
239 rdf:type schema:Person
240 sg:person.014034124411.30 schema:affiliation grid-institutes:grid.134936.a
241 schema:familyName Rocca
242 schema:givenName Gregory J Della
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014034124411.30
244 rdf:type schema:Person
245 sg:person.0577123715.04 schema:affiliation grid-institutes:None
246 schema:familyName Jones
247 schema:givenName John
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577123715.04
249 rdf:type schema:Person
250 sg:person.0650346750.97 schema:affiliation grid-institutes:None
251 schema:familyName Steen
252 schema:givenName R Grant
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650346750.97
254 rdf:type schema:Person
255 sg:pub.10.1007/bf02390832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033546805
256 https://doi.org/10.1007/bf02390832
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/pl00021234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074583283
259 https://doi.org/10.1007/pl00021234
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/s00167-010-1335-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005086303
262 https://doi.org/10.1007/s00167-010-1335-6
263 rdf:type schema:CreativeWork
264 sg:pub.10.1007/s00223-013-9785-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049576656
265 https://doi.org/10.1007/s00223-013-9785-8
266 rdf:type schema:CreativeWork
267 sg:pub.10.1007/s00402-012-1631-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020719098
268 https://doi.org/10.1007/s00402-012-1631-3
269 rdf:type schema:CreativeWork
270 sg:pub.10.1007/s00590-011-0936-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008006063
271 https://doi.org/10.1007/s00590-011-0936-1
272 rdf:type schema:CreativeWork
273 sg:pub.10.1007/s11999-009-1162-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014535631
274 https://doi.org/10.1007/s11999-009-1162-6
275 rdf:type schema:CreativeWork
276 grid-institutes:None schema:alternateName Medical Affairs, Bioventus LLC, Durham, NC, USA
277 schema:name Medical Affairs, Bioventus LLC, Durham, NC, USA
278 rdf:type schema:Organization
279 grid-institutes:grid.134936.a schema:alternateName Department of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA
280 schema:name Department of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA
281 rdf:type schema:Organization
282 grid-institutes:grid.189509.c schema:alternateName Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA
283 schema:name Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA
284 rdf:type schema:Organization
285 grid-institutes:grid.411115.1 schema:alternateName Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
286 schema:name Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
287 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...