Incidence rate of sexually transmitted infections among HIV infected patients on long-term ART in an urban and a rural clinic ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Stephen Okoboi, Barbara Castelnuovo, David M. Moore, Joseph Musaazi, Andrew Kambugu, Josephine Birungi, Mastula Nanfuka, Annelies Van Rie

ABSTRACT

BACKGROUND: HIV immunosuppression increases susceptibility to other STIs and STIs can enhance HIV transmission, reduce CD4 cell count and increase viral load. Co-infections of HIV and STIs may thus reduce the preventive benefits of ART. Little is known about the incidence rate of STIs among long-term patients on ART. METHOD: We conducted a secondary data analysis of all patients enrolled in a rural and an urban longitudinal cohort studies who initiated ART between April 2003 and July 2007 followed up to 2016. Patients were screened for STI every three months using "a syndromic and case management approaches". STI incidence rate, was defined as the number of new cases per population at risk over the follow-up review period. We performed a time-to-event and Kaplan Meier analysis. We used a multivariable Cox proportional hazards regression model to assess for factors associated with STI incidence. RESULT: Of 1012 participants, 402 (39.8%) were urban and 610 (60.2%) rural residents. Mean age was 42.8 years (SD 8.5). The total number of follow up time was 44,304 person years. We observed STI incidence rate of 2.1 per 1000 person-years after follow-up. Rural residence (adjusted hazard ratio [aHR] 3.53, 95% CI: 1.95-6.39), younger age (aHR 2.05, 95% CI: 1.02-4.12 for 18-34 years and aHR 1.65, 95% CI: 1.00-2.72 for 35-44 years) were factors associated with higher incidence of STIs. Being male (aHR 0.51, 95% CI: 0.27-0.93) was associated with a lower incidence of STIs. CONCLUSION: We found STIs incidence rate of approximately 3 per 1000 person-years among patients on long-term (≥ 4 years) ART followed up-to 3.5 years. Rural and younger persons on ART should be routinely screened for STIs because high incidence of STIs may undo the preventative effects of ART for all. More... »

PAGES

87

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12889-019-6417-x

DOI

http://dx.doi.org/10.1186/s12889-019-6417-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111504743

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30658611


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Retroviral Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Longitudinal Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rural Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sexually Transmitted Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Uganda", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urban Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.5284.b", 
          "name": [
            "Infectious Diseases Institute; College of Health Sciences, Makerere University, P.O BOX 22418, Kampala, Uganda", 
            "Global Health Institute; University of Antwerp, Antwerp, Belgium", 
            "Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okoboi", 
        "givenName": "Stephen", 
        "id": "sg:person.0705524057.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705524057.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Makerere University", 
          "id": "https://www.grid.ac/institutes/grid.11194.3c", 
          "name": [
            "Infectious Diseases Institute; College of Health Sciences, Makerere University, P.O BOX 22418, Kampala, Uganda"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Castelnuovo", 
        "givenName": "Barbara", 
        "id": "sg:person.01120312242.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120312242.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of British Columbia", 
          "id": "https://www.grid.ac/institutes/grid.17091.3e", 
          "name": [
            "British Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada", 
            "University of British Columbia, Vancouver, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moore", 
        "givenName": "David M.", 
        "id": "sg:person.011507471272.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011507471272.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Makerere University", 
          "id": "https://www.grid.ac/institutes/grid.11194.3c", 
          "name": [
            "Infectious Diseases Institute; College of Health Sciences, Makerere University, P.O BOX 22418, Kampala, Uganda"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Musaazi", 
        "givenName": "Joseph", 
        "id": "sg:person.01071046126.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071046126.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Makerere University", 
          "id": "https://www.grid.ac/institutes/grid.11194.3c", 
          "name": [
            "Infectious Diseases Institute; College of Health Sciences, Makerere University, P.O BOX 22418, Kampala, Uganda"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kambugu", 
        "givenName": "Andrew", 
        "id": "sg:person.01302654042.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302654042.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The AIDS Support Organization", 
          "id": "https://www.grid.ac/institutes/grid.422943.a", 
          "name": [
            "The AIDS Support Organization, Kampala, Uganda"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Birungi", 
        "givenName": "Josephine", 
        "id": "sg:person.0613320011.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613320011.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The AIDS Support Organization", 
          "id": "https://www.grid.ac/institutes/grid.422943.a", 
          "name": [
            "The AIDS Support Organization, Kampala, Uganda"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nanfuka", 
        "givenName": "Mastula", 
        "id": "sg:person.01153332153.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153332153.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Antwerp", 
          "id": "https://www.grid.ac/institutes/grid.5284.b", 
          "name": [
            "Global Health Institute; University of Antwerp, Antwerp, Belgium", 
            "Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Rie", 
        "givenName": "Annelies", 
        "id": "sg:person.01150514637.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150514637.42"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1136/sti.73.3.228-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000394069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.73.3.228-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000394069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-3156.2002.00963.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005596603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1742-4755-6-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007751435", 
          "https://doi.org/10.1186/1742-4755-6-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/0956462961918211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009537811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/0956462961918211", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009537811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/592303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013621183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12981-015-0077-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018774816", 
          "https://doi.org/10.1186/s12981-015-0077-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1742-6405-11-31", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020489714", 
          "https://doi.org/10.1186/1742-6405-11-31"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.73.3.229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026748899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.73.3.229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026748899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.srhc.2010.03.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027225772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1468-1293.2009.00818.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028686621"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0897.2010.00942.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028882538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/427262", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029677840"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4236/wja.2012.23022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030368737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0122400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031661662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0122400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031661662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/olq.0b013e3181812d15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034081325"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/olq.0b013e3181812d15", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034081325"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.72.2.83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036319129"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.72.2.83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036319129"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sextrans-2013-051446", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036333378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sextrans-2013-051446", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036333378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e328341fb18", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036740320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/qad.0b013e328341fb18", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036740320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.2010.047514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037494115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/sti.2010.047514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037494115"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0132182", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039193800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1472-698x-12-11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044768173", 
          "https://doi.org/10.1186/1472-698x-12-11"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7448/ias.19.1.20773", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048006173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007435-199219020-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052916215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007435-199219020-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052916215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/ijsa.2007.007273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053636570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/ijsa.2007.007273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053636570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2105/ajph.2009.184796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068844884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4103/0253-7184.74998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072237558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077409715", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.1002485", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100303558"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: HIV immunosuppression increases susceptibility to other STIs and STIs can enhance HIV transmission, reduce CD4 cell count and increase viral load. Co-infections of HIV and STIs may thus reduce the preventive benefits of ART. Little is known about the incidence rate of STIs among long-term patients on ART.\nMETHOD: We conducted a secondary data analysis of all patients enrolled in a rural and an urban longitudinal cohort studies who initiated ART between April 2003 and July 2007 followed up to 2016. Patients were screened for STI every three months using \"a syndromic and case management approaches\". STI incidence rate, was defined as the number of new cases per population at risk over the follow-up review period. We performed a time-to-event and Kaplan Meier analysis. We used a multivariable Cox proportional hazards regression model to assess for factors associated with STI incidence.\nRESULT: Of 1012 participants, 402 (39.8%) were urban and 610 (60.2%) rural residents. Mean age was 42.8\u2009years (SD 8.5). The total number of follow up time was 44,304 person years. We observed STI incidence rate of 2.1 per 1000 person-years after follow-up. Rural residence (adjusted hazard ratio [aHR] 3.53, 95% CI: 1.95-6.39), younger age (aHR 2.05, 95% CI: 1.02-4.12 for 18-34\u2009years and aHR 1.65, 95% CI: 1.00-2.72 for 35-44\u2009years) were factors associated with higher incidence of STIs. Being male (aHR 0.51, 95% CI: 0.27-0.93) was associated with a lower incidence of STIs.\nCONCLUSION: We found STIs incidence rate of approximately 3 per 1000 person-years among patients on long-term (\u2265 4\u2009years) ART followed up-to 3.5\u2009years. Rural and younger persons on ART should be routinely screened for STIs because high incidence of STIs may undo the preventative effects of ART for all.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12889-019-6417-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024954", 
        "issn": [
          "1471-2458"
        ], 
        "name": "BMC Public Health", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "Incidence rate of sexually transmitted infections among HIV infected patients on long-term ART in an urban and a rural clinic in Uganda", 
    "pagination": "87", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12889-019-6417-x"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "04f7e57218c6b0eddd5b7831e3980fa00b65d7051ab125071efd81ff3669f2aa"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1111504743"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100968562"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30658611"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12889-019-6417-x", 
      "https://app.dimensions.ai/details/publication/pub.1111504743"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000376_0000000376/records_56176_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12889-019-6417-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12889-019-6417-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12889-019-6417-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12889-019-6417-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12889-019-6417-x'


 

This table displays all metadata directly associated to this object as RDF triples.

276 TRIPLES      21 PREDICATES      72 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12889-019-6417-x schema:about N11b991c5f6c649f7b3b4a159b73c2449
2 N21d93b2f3c50429082c554fbb9b07962
3 N3499efb84fd54465b09ebeaedd37ccf1
4 N671c329127e94e0297808e34c8e2869c
5 N74f051610866425abc3a318d91c4a4e9
6 Na76f64c68d1c4e569cb8ed85d7369245
7 Naf0aeb05fdd24b1d8fcb6b87d1c79ede
8 Nc56235d1b91845998d4e20852998209a
9 Nca8dd7b04f5644fcbc5daa5d320a3fd4
10 Nd4317df6484a4a958be63c0cb82f5514
11 Nd75f2725e90b4e4ab542db181f5c1505
12 Nde2c0c24262b4b2a8e427f245cb5e625
13 Ne62217d91c4147439eead1c888735d43
14 Ne8f66ddafd104528aa748d7f31cdd115
15 Nf49512ee24584f1bac84ae9ab060a543
16 anzsrc-for:11
17 anzsrc-for:1117
18 schema:author N29ebdb2a872449a688b58d91f516bd08
19 schema:citation sg:pub.10.1186/1472-698x-12-11
20 sg:pub.10.1186/1742-4755-6-4
21 sg:pub.10.1186/1742-6405-11-31
22 sg:pub.10.1186/s12981-015-0077-4
23 https://app.dimensions.ai/details/publication/pub.1077409715
24 https://doi.org/10.1016/j.srhc.2010.03.001
25 https://doi.org/10.1046/j.1365-3156.2002.00963.x
26 https://doi.org/10.1086/427262
27 https://doi.org/10.1086/592303
28 https://doi.org/10.1097/00007435-199219020-00001
29 https://doi.org/10.1097/olq.0b013e3181812d15
30 https://doi.org/10.1097/qad.0b013e328341fb18
31 https://doi.org/10.1111/j.1468-1293.2009.00818.x
32 https://doi.org/10.1111/j.1600-0897.2010.00942.x
33 https://doi.org/10.1136/sextrans-2013-051446
34 https://doi.org/10.1136/sti.2010.047514
35 https://doi.org/10.1136/sti.72.2.83
36 https://doi.org/10.1136/sti.73.3.228-a
37 https://doi.org/10.1136/sti.73.3.229
38 https://doi.org/10.1258/0956462961918211
39 https://doi.org/10.1258/ijsa.2007.007273
40 https://doi.org/10.1371/journal.pmed.1002485
41 https://doi.org/10.1371/journal.pone.0122400
42 https://doi.org/10.1371/journal.pone.0132182
43 https://doi.org/10.2105/ajph.2009.184796
44 https://doi.org/10.4103/0253-7184.74998
45 https://doi.org/10.4236/wja.2012.23022
46 https://doi.org/10.7448/ias.19.1.20773
47 schema:datePublished 2019-12
48 schema:datePublishedReg 2019-12-01
49 schema:description BACKGROUND: HIV immunosuppression increases susceptibility to other STIs and STIs can enhance HIV transmission, reduce CD4 cell count and increase viral load. Co-infections of HIV and STIs may thus reduce the preventive benefits of ART. Little is known about the incidence rate of STIs among long-term patients on ART. METHOD: We conducted a secondary data analysis of all patients enrolled in a rural and an urban longitudinal cohort studies who initiated ART between April 2003 and July 2007 followed up to 2016. Patients were screened for STI every three months using "a syndromic and case management approaches". STI incidence rate, was defined as the number of new cases per population at risk over the follow-up review period. We performed a time-to-event and Kaplan Meier analysis. We used a multivariable Cox proportional hazards regression model to assess for factors associated with STI incidence. RESULT: Of 1012 participants, 402 (39.8%) were urban and 610 (60.2%) rural residents. Mean age was 42.8 years (SD 8.5). The total number of follow up time was 44,304 person years. We observed STI incidence rate of 2.1 per 1000 person-years after follow-up. Rural residence (adjusted hazard ratio [aHR] 3.53, 95% CI: 1.95-6.39), younger age (aHR 2.05, 95% CI: 1.02-4.12 for 18-34 years and aHR 1.65, 95% CI: 1.00-2.72 for 35-44 years) were factors associated with higher incidence of STIs. Being male (aHR 0.51, 95% CI: 0.27-0.93) was associated with a lower incidence of STIs. CONCLUSION: We found STIs incidence rate of approximately 3 per 1000 person-years among patients on long-term (≥ 4 years) ART followed up-to 3.5 years. Rural and younger persons on ART should be routinely screened for STIs because high incidence of STIs may undo the preventative effects of ART for all.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree true
53 schema:isPartOf N07dead670fcd4e4ca03a2e9e783160dc
54 Nfa8f6da4f7554bbbafc8d7ca16d8f89d
55 sg:journal.1024954
56 schema:name Incidence rate of sexually transmitted infections among HIV infected patients on long-term ART in an urban and a rural clinic in Uganda
57 schema:pagination 87
58 schema:productId N09d17d4747cb4115aea09ac74033a4a6
59 N130cb6b733784ce3ab2d15297970b1c9
60 N880f92f6b6bd464d9b1f0dada074fad7
61 N8a74013b687848bebc489f52cfd834dd
62 Na7b3c34b1f1742b480cfd070852435ad
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111504743
64 https://doi.org/10.1186/s12889-019-6417-x
65 schema:sdDatePublished 2019-04-15T09:19
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher Nf86115d3fa054aac87434e3634e39ff4
68 schema:url https://link.springer.com/10.1186%2Fs12889-019-6417-x
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N07dead670fcd4e4ca03a2e9e783160dc schema:issueNumber 1
73 rdf:type schema:PublicationIssue
74 N09d17d4747cb4115aea09ac74033a4a6 schema:name readcube_id
75 schema:value 04f7e57218c6b0eddd5b7831e3980fa00b65d7051ab125071efd81ff3669f2aa
76 rdf:type schema:PropertyValue
77 N0da374c470e44e69a14a2cd335b05d3f rdf:first sg:person.01302654042.54
78 rdf:rest Nc10aa023cbc04f1cba5691ba7959ae53
79 N11b991c5f6c649f7b3b4a159b73c2449 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Female
81 rdf:type schema:DefinedTerm
82 N130cb6b733784ce3ab2d15297970b1c9 schema:name doi
83 schema:value 10.1186/s12889-019-6417-x
84 rdf:type schema:PropertyValue
85 N18256efb668143a6846b525bcb7e618c rdf:first sg:person.01150514637.42
86 rdf:rest rdf:nil
87 N21d93b2f3c50429082c554fbb9b07962 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Adult
89 rdf:type schema:DefinedTerm
90 N29ebdb2a872449a688b58d91f516bd08 rdf:first sg:person.0705524057.19
91 rdf:rest Na1f1558a3bfe4a698ef3e9f95f392d65
92 N3499efb84fd54465b09ebeaedd37ccf1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Anti-Retroviral Agents
94 rdf:type schema:DefinedTerm
95 N3fa952f902fa445dbc5f18f305d82d69 rdf:first sg:person.01071046126.42
96 rdf:rest N0da374c470e44e69a14a2cd335b05d3f
97 N671c329127e94e0297808e34c8e2869c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Young Adult
99 rdf:type schema:DefinedTerm
100 N74f051610866425abc3a318d91c4a4e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Longitudinal Studies
102 rdf:type schema:DefinedTerm
103 N880f92f6b6bd464d9b1f0dada074fad7 schema:name dimensions_id
104 schema:value pub.1111504743
105 rdf:type schema:PropertyValue
106 N8a74013b687848bebc489f52cfd834dd schema:name pubmed_id
107 schema:value 30658611
108 rdf:type schema:PropertyValue
109 Na1f1558a3bfe4a698ef3e9f95f392d65 rdf:first sg:person.01120312242.23
110 rdf:rest Na7fda5e232444a42b2ad74b509a9c998
111 Na76f64c68d1c4e569cb8ed85d7369245 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Humans
113 rdf:type schema:DefinedTerm
114 Na7b3c34b1f1742b480cfd070852435ad schema:name nlm_unique_id
115 schema:value 100968562
116 rdf:type schema:PropertyValue
117 Na7fda5e232444a42b2ad74b509a9c998 rdf:first sg:person.011507471272.04
118 rdf:rest N3fa952f902fa445dbc5f18f305d82d69
119 Naf0aeb05fdd24b1d8fcb6b87d1c79ede schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name HIV Infections
121 rdf:type schema:DefinedTerm
122 Nc10aa023cbc04f1cba5691ba7959ae53 rdf:first sg:person.0613320011.09
123 rdf:rest Nd537bba12ea544b298ae27cd0815c9a5
124 Nc56235d1b91845998d4e20852998209a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Sexually Transmitted Diseases
126 rdf:type schema:DefinedTerm
127 Nca8dd7b04f5644fcbc5daa5d320a3fd4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Incidence
129 rdf:type schema:DefinedTerm
130 Nd4317df6484a4a958be63c0cb82f5514 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Middle Aged
132 rdf:type schema:DefinedTerm
133 Nd537bba12ea544b298ae27cd0815c9a5 rdf:first sg:person.01153332153.10
134 rdf:rest N18256efb668143a6846b525bcb7e618c
135 Nd75f2725e90b4e4ab542db181f5c1505 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Male
137 rdf:type schema:DefinedTerm
138 Nde2c0c24262b4b2a8e427f245cb5e625 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Rural Health Services
140 rdf:type schema:DefinedTerm
141 Ne62217d91c4147439eead1c888735d43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Uganda
143 rdf:type schema:DefinedTerm
144 Ne8f66ddafd104528aa748d7f31cdd115 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Adolescent
146 rdf:type schema:DefinedTerm
147 Nf49512ee24584f1bac84ae9ab060a543 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Urban Health Services
149 rdf:type schema:DefinedTerm
150 Nf86115d3fa054aac87434e3634e39ff4 schema:name Springer Nature - SN SciGraph project
151 rdf:type schema:Organization
152 Nfa8f6da4f7554bbbafc8d7ca16d8f89d schema:volumeNumber 19
153 rdf:type schema:PublicationVolume
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
158 schema:name Public Health and Health Services
159 rdf:type schema:DefinedTerm
160 sg:journal.1024954 schema:issn 1471-2458
161 schema:name BMC Public Health
162 rdf:type schema:Periodical
163 sg:person.01071046126.42 schema:affiliation https://www.grid.ac/institutes/grid.11194.3c
164 schema:familyName Musaazi
165 schema:givenName Joseph
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071046126.42
167 rdf:type schema:Person
168 sg:person.01120312242.23 schema:affiliation https://www.grid.ac/institutes/grid.11194.3c
169 schema:familyName Castelnuovo
170 schema:givenName Barbara
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120312242.23
172 rdf:type schema:Person
173 sg:person.01150514637.42 schema:affiliation https://www.grid.ac/institutes/grid.5284.b
174 schema:familyName Van Rie
175 schema:givenName Annelies
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150514637.42
177 rdf:type schema:Person
178 sg:person.011507471272.04 schema:affiliation https://www.grid.ac/institutes/grid.17091.3e
179 schema:familyName Moore
180 schema:givenName David M.
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011507471272.04
182 rdf:type schema:Person
183 sg:person.01153332153.10 schema:affiliation https://www.grid.ac/institutes/grid.422943.a
184 schema:familyName Nanfuka
185 schema:givenName Mastula
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153332153.10
187 rdf:type schema:Person
188 sg:person.01302654042.54 schema:affiliation https://www.grid.ac/institutes/grid.11194.3c
189 schema:familyName Kambugu
190 schema:givenName Andrew
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302654042.54
192 rdf:type schema:Person
193 sg:person.0613320011.09 schema:affiliation https://www.grid.ac/institutes/grid.422943.a
194 schema:familyName Birungi
195 schema:givenName Josephine
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613320011.09
197 rdf:type schema:Person
198 sg:person.0705524057.19 schema:affiliation https://www.grid.ac/institutes/grid.5284.b
199 schema:familyName Okoboi
200 schema:givenName Stephen
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705524057.19
202 rdf:type schema:Person
203 sg:pub.10.1186/1472-698x-12-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044768173
204 https://doi.org/10.1186/1472-698x-12-11
205 rdf:type schema:CreativeWork
206 sg:pub.10.1186/1742-4755-6-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007751435
207 https://doi.org/10.1186/1742-4755-6-4
208 rdf:type schema:CreativeWork
209 sg:pub.10.1186/1742-6405-11-31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020489714
210 https://doi.org/10.1186/1742-6405-11-31
211 rdf:type schema:CreativeWork
212 sg:pub.10.1186/s12981-015-0077-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018774816
213 https://doi.org/10.1186/s12981-015-0077-4
214 rdf:type schema:CreativeWork
215 https://app.dimensions.ai/details/publication/pub.1077409715 schema:CreativeWork
216 https://doi.org/10.1016/j.srhc.2010.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027225772
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1046/j.1365-3156.2002.00963.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005596603
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1086/427262 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029677840
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1086/592303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013621183
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1097/00007435-199219020-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052916215
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1097/olq.0b013e3181812d15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034081325
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1097/qad.0b013e328341fb18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036740320
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1111/j.1468-1293.2009.00818.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028686621
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1111/j.1600-0897.2010.00942.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028882538
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1136/sextrans-2013-051446 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036333378
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1136/sti.2010.047514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037494115
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1136/sti.72.2.83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036319129
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1136/sti.73.3.228-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1000394069
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1136/sti.73.3.229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026748899
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1258/0956462961918211 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009537811
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1258/ijsa.2007.007273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053636570
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1371/journal.pmed.1002485 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100303558
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1371/journal.pone.0122400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031661662
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1371/journal.pone.0132182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039193800
253 rdf:type schema:CreativeWork
254 https://doi.org/10.2105/ajph.2009.184796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068844884
255 rdf:type schema:CreativeWork
256 https://doi.org/10.4103/0253-7184.74998 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072237558
257 rdf:type schema:CreativeWork
258 https://doi.org/10.4236/wja.2012.23022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030368737
259 rdf:type schema:CreativeWork
260 https://doi.org/10.7448/ias.19.1.20773 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048006173
261 rdf:type schema:CreativeWork
262 https://www.grid.ac/institutes/grid.11194.3c schema:alternateName Makerere University
263 schema:name Infectious Diseases Institute; College of Health Sciences, Makerere University, P.O BOX 22418, Kampala, Uganda
264 rdf:type schema:Organization
265 https://www.grid.ac/institutes/grid.17091.3e schema:alternateName University of British Columbia
266 schema:name British Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada
267 University of British Columbia, Vancouver, Canada
268 rdf:type schema:Organization
269 https://www.grid.ac/institutes/grid.422943.a schema:alternateName The AIDS Support Organization
270 schema:name The AIDS Support Organization, Kampala, Uganda
271 rdf:type schema:Organization
272 https://www.grid.ac/institutes/grid.5284.b schema:alternateName University of Antwerp
273 schema:name Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium
274 Global Health Institute; University of Antwerp, Antwerp, Belgium
275 Infectious Diseases Institute; College of Health Sciences, Makerere University, P.O BOX 22418, Kampala, Uganda
276 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...