Evaluation of biochemical and haematological changes in dengue fever and dengue hemorrhagic fever in Sri Lankan children: a prospective follow ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-04-01

AUTHORS

Grace Angeline Malarnangai Kularatnam, Eresha Jasinge, Sunethra Gunasena, Dulani Samaranayake, Manouri Prasanta Senanayake, Vithanage Pujitha Wickramasinghe

ABSTRACT

BACKGROUND: Series of biochemical and haematological changes occur during the course of dengue infection, which vary depending on the clinical disease. The patterns of change are not well documented and identifying these patterns in children with dengue infection would help to anticipate the progression to different clinical stages thus enabling effective management. METHODS: A prospective follow up study was conducted during the period of July 2013 - April 2014 at Professorial Pediatric unit, Lady Ridgeway Hospital for Children, Colombo, Sri Lanka. Children (5-12 years) admitted within the first 84 h of fever, with a clinical diagnosis of dengue infection were recruited. Children who became positive for dengue IgM were included in the final analysis. Blood was collected on admission for complete blood count, Alanine aminotransferase, Aspartate aminotransferase, albumin, cholesterol and corrected calcium. These tests were repeated at 12 hourly intervals during the hospital stay. RESULTS: Data of 130-subjects were analyzed (Dengue fever /Dengue hemorrhagic fever: 100/30). There was a significant difference in the pattern of white cell counts, platelets and haematocrit in the two clinical groups. Both transaminase rose initially in both dengue fever and dengue hemorrhagic fever and a steep rise were seen between 8th and 9th days in hemorrhagic fever. Both albumin and cholesterol decreased significantly at the time of entering into the critical phase. According to Receiver operating characteristic curve analysis, albumin level crossing 37.5g/L (sensitivity 86.7%, specificity 77.8%) and a 0.38 mmol/L reduction in cholesterol level (sensitivity 77.3%, specificity 71.9%) between day 3 and 4 were the best predictors of entering into critical phase. Calcium levels did not show any distinct pattern. CONCLUSIONS: There is a clear difference in the pattern of change of both hematological and biochemical parameters in dengue fever and dengue hemorrhagic fever. Reduction in albumin and cholesterol levels seen between the completion of day 3 and day 4 were highly valid predictors of entering into critical phase in dengue hemorrhagic fever. More... »

PAGES

87

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12887-019-1451-5

DOI

http://dx.doi.org/10.1186/s12887-019-1451-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113170575

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30935373


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Cell Count", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Calcium", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child, Preschool", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholesterol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dengue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Function Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "ROC Curve", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serum Albumin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Severe Dengue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sri Lanka", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transaminases", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Dehiwela, Sri Lanka", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Chemical Pathology, Lady Ridgeway Hospital for children, Colombo, 08 Sri Lanka", 
            "Dehiwela, Sri Lanka"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kularatnam", 
        "givenName": "Grace Angeline Malarnangai", 
        "id": "sg:person.012066552157.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012066552157.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Chemical Pathology, Lady Ridgeway Hospital for children, Colombo, 08 Sri Lanka", 
          "id": "http://www.grid.ac/institutes/grid.415728.d", 
          "name": [
            "Department of Chemical Pathology, Lady Ridgeway Hospital for children, Colombo, 08 Sri Lanka"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jasinge", 
        "givenName": "Eresha", 
        "id": "sg:person.0770220504.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770220504.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Virology, Medical Research Institute, Colombo, 08 Sri Lanka", 
          "id": "http://www.grid.ac/institutes/grid.415115.5", 
          "name": [
            "Department of Virology, Medical Research Institute, Colombo, 08 Sri Lanka"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gunasena", 
        "givenName": "Sunethra", 
        "id": "sg:person.0725616516.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725616516.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Community Medicine, Faculty of Medicine, Colombo, Sri Lanka", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Community Medicine, Faculty of Medicine, Colombo, Sri Lanka"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Samaranayake", 
        "givenName": "Dulani", 
        "id": "sg:person.012500065734.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012500065734.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatrics, Faculty of Medicine, Colombo, Sri Lanka", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Pediatrics, Faculty of Medicine, Colombo, Sri Lanka"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Senanayake", 
        "givenName": "Manouri Prasanta", 
        "id": "sg:person.011014465162.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011014465162.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pediatrics, Faculty of Medicine, Colombo, Sri Lanka", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Pediatrics, Faculty of Medicine, Colombo, Sri Lanka"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wickramasinghe", 
        "givenName": "Vithanage Pujitha", 
        "id": "sg:person.011524300234.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011524300234.44"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/s12879-016-1671-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053021014", 
          "https://doi.org/10.1186/s12879-016-1671-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12879-018-2996-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101179347", 
          "https://doi.org/10.1186/s12879-018-2996-x"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04-01", 
    "datePublishedReg": "2019-04-01", 
    "description": "BACKGROUND: Series of biochemical and haematological changes occur during the course of dengue infection, which vary depending on the clinical disease. The patterns of change are not well documented and identifying these patterns in children with dengue infection would help to anticipate the progression to different clinical stages thus enabling effective management.\nMETHODS: A prospective follow up study was conducted during the period of July 2013 - April 2014 at Professorial Pediatric unit, Lady Ridgeway Hospital for Children, Colombo, Sri Lanka. Children (5-12\u2009years) admitted within the first 84\u2009h of fever, with a clinical diagnosis of dengue infection were recruited. Children who became positive for dengue IgM were included in the final analysis. Blood was collected on admission for complete blood count, Alanine aminotransferase, Aspartate aminotransferase, albumin, cholesterol and corrected calcium. These tests were repeated at 12 hourly intervals during the hospital stay.\nRESULTS: Data of 130-subjects were analyzed (Dengue fever /Dengue hemorrhagic fever: 100/30). There was a significant difference in the pattern of white cell counts, platelets and haematocrit in the two clinical groups. Both transaminase rose initially in both dengue fever and dengue hemorrhagic fever and a steep rise were seen between 8th and 9th days in hemorrhagic fever. Both albumin and cholesterol decreased significantly at the time of entering into the critical phase. According to Receiver operating characteristic curve analysis, albumin level crossing 37.5g/L (sensitivity 86.7%, specificity 77.8%) and a 0.38\u2009mmol/L reduction in cholesterol level (sensitivity 77.3%, specificity 71.9%) between day 3 and 4 were the best predictors of entering into critical phase. Calcium levels did not show any distinct pattern.\nCONCLUSIONS: There is a clear difference in the pattern of change of both hematological and biochemical parameters in dengue fever and dengue hemorrhagic fever. Reduction in albumin and cholesterol levels seen between the completion of day 3 and day 4 were highly valid predictors of entering into critical phase in dengue hemorrhagic fever.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12887-019-1451-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024635", 
        "issn": [
          "1471-2431"
        ], 
        "name": "BMC Pediatrics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "keywords": [
      "dengue hemorrhagic fever", 
      "hemorrhagic fever", 
      "dengue infection", 
      "dengue fever", 
      "prospective follow", 
      "cholesterol levels", 
      "haematological changes", 
      "day 3", 
      "Professorial Paediatric Unit", 
      "Lady Ridgeway Hospital", 
      "different clinical stages", 
      "white cell count", 
      "complete blood count", 
      "characteristic curve analysis", 
      "Sri Lankan children", 
      "patterns of change", 
      "hospital stay", 
      "dengue IgM", 
      "clinical stage", 
      "pediatric unit", 
      "blood count", 
      "alanine aminotransferase", 
      "clinical disease", 
      "calcium levels", 
      "fever", 
      "cell count", 
      "day 4", 
      "clinical diagnosis", 
      "aspartate aminotransferase", 
      "clinical groups", 
      "biochemical parameters", 
      "final analysis", 
      "curve analysis", 
      "infection", 
      "series of biochemical", 
      "significant differences", 
      "children", 
      "follow", 
      "cholesterol", 
      "hourly intervals", 
      "aminotransferase", 
      "period of July", 
      "albumin", 
      "valid predictor", 
      "distinct patterns", 
      "best predictor", 
      "predictors", 
      "critical phase", 
      "count", 
      "admission", 
      "stay", 
      "hospital", 
      "IgM", 
      "levels", 
      "disease", 
      "transaminase", 
      "diagnosis", 
      "blood", 
      "progression", 
      "haematocrit", 
      "effective management", 
      "platelets", 
      "differences", 
      "changes", 
      "study", 
      "clear differences", 
      "steep rise", 
      "days", 
      "calcium", 
      "reduction", 
      "patterns", 
      "group", 
      "biochemical", 
      "Sri Lanka", 
      "course", 
      "intervals", 
      "completion", 
      "management", 
      "period", 
      "evaluation", 
      "test", 
      "analysis", 
      "stage", 
      "Colombo", 
      "data", 
      "units", 
      "time", 
      "Lanka", 
      "series", 
      "receiver", 
      "rise", 
      "phase", 
      "parameters", 
      "Ridgeway Hospital", 
      "Lankan children"
    ], 
    "name": "Evaluation of biochemical and haematological changes in dengue fever and dengue hemorrhagic fever in Sri Lankan children: a prospective follow up study", 
    "pagination": "87", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113170575"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12887-019-1451-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30935373"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12887-019-1451-5", 
      "https://app.dimensions.ai/details/publication/pub.1113170575"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:53", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_824.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12887-019-1451-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12887-019-1451-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12887-019-1451-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12887-019-1451-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12887-019-1451-5'


 

This table displays all metadata directly associated to this object as RDF triples.

286 TRIPLES      22 PREDICATES      142 URIs      132 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12887-019-1451-5 schema:about N0107475ae1aa4f9798625d1dd8573ee4
2 N03a333c6b18345bda0f2cfd0ce9f6f6d
3 N1399239e036d443a8c1ac3e2ca87e198
4 N1801a633ec0949ecab0a7198ae701cc1
5 N2e8d33e4051f45e58b18872eb4a43be1
6 N3c27960b516f4fc59b391726a3accd3e
7 N3d2872040d1742a69c49453aed4b8282
8 N483e162c6b5c4e44a1f0e93d5f60458c
9 N5833b9783e0c4b68ab9dcfeee4b867cf
10 N61b3115a56cb4756b0ebed7d8523072b
11 N70fd9a17aaab4f50b54339fddd9bdf42
12 Na5bffe471fb7441bbb1d5118aac28b35
13 Nbaae9de1b5d74eb0a575c8d75933126f
14 Nbf25c1eb5d824766a8921e3bd47ea4aa
15 Nc31fe847e3b44724b096671777223f02
16 Ne4f926044a6b403582ff9f01a06979b7
17 Nf67cd159b8dd4922adf98e7cc262678a
18 Nf6f6c03880ec49aa94ca4092aecc679d
19 Nf99b941abde44cc09390209214fd98a4
20 anzsrc-for:11
21 anzsrc-for:1117
22 schema:author N366bae3f913444af9fef77e22c4ba0c2
23 schema:citation sg:pub.10.1186/s12879-016-1671-3
24 sg:pub.10.1186/s12879-018-2996-x
25 schema:datePublished 2019-04-01
26 schema:datePublishedReg 2019-04-01
27 schema:description BACKGROUND: Series of biochemical and haematological changes occur during the course of dengue infection, which vary depending on the clinical disease. The patterns of change are not well documented and identifying these patterns in children with dengue infection would help to anticipate the progression to different clinical stages thus enabling effective management. METHODS: A prospective follow up study was conducted during the period of July 2013 - April 2014 at Professorial Pediatric unit, Lady Ridgeway Hospital for Children, Colombo, Sri Lanka. Children (5-12 years) admitted within the first 84 h of fever, with a clinical diagnosis of dengue infection were recruited. Children who became positive for dengue IgM were included in the final analysis. Blood was collected on admission for complete blood count, Alanine aminotransferase, Aspartate aminotransferase, albumin, cholesterol and corrected calcium. These tests were repeated at 12 hourly intervals during the hospital stay. RESULTS: Data of 130-subjects were analyzed (Dengue fever /Dengue hemorrhagic fever: 100/30). There was a significant difference in the pattern of white cell counts, platelets and haematocrit in the two clinical groups. Both transaminase rose initially in both dengue fever and dengue hemorrhagic fever and a steep rise were seen between 8th and 9th days in hemorrhagic fever. Both albumin and cholesterol decreased significantly at the time of entering into the critical phase. According to Receiver operating characteristic curve analysis, albumin level crossing 37.5g/L (sensitivity 86.7%, specificity 77.8%) and a 0.38 mmol/L reduction in cholesterol level (sensitivity 77.3%, specificity 71.9%) between day 3 and 4 were the best predictors of entering into critical phase. Calcium levels did not show any distinct pattern. CONCLUSIONS: There is a clear difference in the pattern of change of both hematological and biochemical parameters in dengue fever and dengue hemorrhagic fever. Reduction in albumin and cholesterol levels seen between the completion of day 3 and day 4 were highly valid predictors of entering into critical phase in dengue hemorrhagic fever.
28 schema:genre article
29 schema:inLanguage en
30 schema:isAccessibleForFree true
31 schema:isPartOf N07ebb993bc1f4e238054e435141a619f
32 N62f35a45fd24429fbdc3dce0e3a6e090
33 sg:journal.1024635
34 schema:keywords Colombo
35 IgM
36 Lady Ridgeway Hospital
37 Lanka
38 Lankan children
39 Professorial Paediatric Unit
40 Ridgeway Hospital
41 Sri Lanka
42 Sri Lankan children
43 admission
44 alanine aminotransferase
45 albumin
46 aminotransferase
47 analysis
48 aspartate aminotransferase
49 best predictor
50 biochemical
51 biochemical parameters
52 blood
53 blood count
54 calcium
55 calcium levels
56 cell count
57 changes
58 characteristic curve analysis
59 children
60 cholesterol
61 cholesterol levels
62 clear differences
63 clinical diagnosis
64 clinical disease
65 clinical groups
66 clinical stage
67 complete blood count
68 completion
69 count
70 course
71 critical phase
72 curve analysis
73 data
74 day 3
75 day 4
76 days
77 dengue IgM
78 dengue fever
79 dengue hemorrhagic fever
80 dengue infection
81 diagnosis
82 differences
83 different clinical stages
84 disease
85 distinct patterns
86 effective management
87 evaluation
88 fever
89 final analysis
90 follow
91 group
92 haematocrit
93 haematological changes
94 hemorrhagic fever
95 hospital
96 hospital stay
97 hourly intervals
98 infection
99 intervals
100 levels
101 management
102 parameters
103 patterns
104 patterns of change
105 pediatric unit
106 period
107 period of July
108 phase
109 platelets
110 predictors
111 progression
112 prospective follow
113 receiver
114 reduction
115 rise
116 series
117 series of biochemical
118 significant differences
119 stage
120 stay
121 steep rise
122 study
123 test
124 time
125 transaminase
126 units
127 valid predictor
128 white cell count
129 schema:name Evaluation of biochemical and haematological changes in dengue fever and dengue hemorrhagic fever in Sri Lankan children: a prospective follow up study
130 schema:pagination 87
131 schema:productId N0e82d414d3dd46d4a2025902f09dca24
132 N5135e61a58dd40238fa539f3affc8fa5
133 Na09c0a8a226e480cb8019fcfb63c43f3
134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113170575
135 https://doi.org/10.1186/s12887-019-1451-5
136 schema:sdDatePublished 2022-01-01T18:53
137 schema:sdLicense https://scigraph.springernature.com/explorer/license/
138 schema:sdPublisher Nc4b423030c1e4e28be85bb592771c6ef
139 schema:url https://doi.org/10.1186/s12887-019-1451-5
140 sgo:license sg:explorer/license/
141 sgo:sdDataset articles
142 rdf:type schema:ScholarlyArticle
143 N0107475ae1aa4f9798625d1dd8573ee4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Sri Lanka
145 rdf:type schema:DefinedTerm
146 N03a333c6b18345bda0f2cfd0ce9f6f6d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Child, Preschool
148 rdf:type schema:DefinedTerm
149 N07ebb993bc1f4e238054e435141a619f schema:issueNumber 1
150 rdf:type schema:PublicationIssue
151 N0e82d414d3dd46d4a2025902f09dca24 schema:name pubmed_id
152 schema:value 30935373
153 rdf:type schema:PropertyValue
154 N1399239e036d443a8c1ac3e2ca87e198 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Blood Cell Count
156 rdf:type schema:DefinedTerm
157 N1801a633ec0949ecab0a7198ae701cc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Male
159 rdf:type schema:DefinedTerm
160 N1e03067727264dabbf803a46ba228668 rdf:first sg:person.0725616516.28
161 rdf:rest Nedc6728041814632a9d180925682991e
162 N25ebc4d18a844c21b0f1b6cf9ae01a72 rdf:first sg:person.0770220504.20
163 rdf:rest N1e03067727264dabbf803a46ba228668
164 N2e8d33e4051f45e58b18872eb4a43be1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Follow-Up Studies
166 rdf:type schema:DefinedTerm
167 N366bae3f913444af9fef77e22c4ba0c2 rdf:first sg:person.012066552157.02
168 rdf:rest N25ebc4d18a844c21b0f1b6cf9ae01a72
169 N3c27960b516f4fc59b391726a3accd3e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name ROC Curve
171 rdf:type schema:DefinedTerm
172 N3d2872040d1742a69c49453aed4b8282 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Dengue
174 rdf:type schema:DefinedTerm
175 N483e162c6b5c4e44a1f0e93d5f60458c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Child
177 rdf:type schema:DefinedTerm
178 N5135e61a58dd40238fa539f3affc8fa5 schema:name dimensions_id
179 schema:value pub.1113170575
180 rdf:type schema:PropertyValue
181 N555568cf8f354d12a5ed3d482b0f3140 rdf:first sg:person.011524300234.44
182 rdf:rest rdf:nil
183 N5833b9783e0c4b68ab9dcfeee4b867cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Prospective Studies
185 rdf:type schema:DefinedTerm
186 N61b3115a56cb4756b0ebed7d8523072b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Cholesterol
188 rdf:type schema:DefinedTerm
189 N62f35a45fd24429fbdc3dce0e3a6e090 schema:volumeNumber 19
190 rdf:type schema:PublicationVolume
191 N70fd9a17aaab4f50b54339fddd9bdf42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
192 schema:name Serum Albumin
193 rdf:type schema:DefinedTerm
194 Na09c0a8a226e480cb8019fcfb63c43f3 schema:name doi
195 schema:value 10.1186/s12887-019-1451-5
196 rdf:type schema:PropertyValue
197 Na5bffe471fb7441bbb1d5118aac28b35 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
198 schema:name Transaminases
199 rdf:type schema:DefinedTerm
200 Naa5987c437934afc8191da4fb86ec32c rdf:first sg:person.011014465162.02
201 rdf:rest N555568cf8f354d12a5ed3d482b0f3140
202 Nbaae9de1b5d74eb0a575c8d75933126f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Calcium
204 rdf:type schema:DefinedTerm
205 Nbf25c1eb5d824766a8921e3bd47ea4aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Liver Function Tests
207 rdf:type schema:DefinedTerm
208 Nc31fe847e3b44724b096671777223f02 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
209 schema:name Sensitivity and Specificity
210 rdf:type schema:DefinedTerm
211 Nc4b423030c1e4e28be85bb592771c6ef schema:name Springer Nature - SN SciGraph project
212 rdf:type schema:Organization
213 Ne4f926044a6b403582ff9f01a06979b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
214 schema:name Female
215 rdf:type schema:DefinedTerm
216 Nedc6728041814632a9d180925682991e rdf:first sg:person.012500065734.26
217 rdf:rest Naa5987c437934afc8191da4fb86ec32c
218 Nf67cd159b8dd4922adf98e7cc262678a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
219 schema:name Humans
220 rdf:type schema:DefinedTerm
221 Nf6f6c03880ec49aa94ca4092aecc679d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
222 schema:name Disease Progression
223 rdf:type schema:DefinedTerm
224 Nf99b941abde44cc09390209214fd98a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
225 schema:name Severe Dengue
226 rdf:type schema:DefinedTerm
227 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
228 schema:name Medical and Health Sciences
229 rdf:type schema:DefinedTerm
230 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
231 schema:name Public Health and Health Services
232 rdf:type schema:DefinedTerm
233 sg:journal.1024635 schema:issn 1471-2431
234 schema:name BMC Pediatrics
235 schema:publisher Springer Nature
236 rdf:type schema:Periodical
237 sg:person.011014465162.02 schema:affiliation grid-institutes:None
238 schema:familyName Senanayake
239 schema:givenName Manouri Prasanta
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011014465162.02
241 rdf:type schema:Person
242 sg:person.011524300234.44 schema:affiliation grid-institutes:None
243 schema:familyName Wickramasinghe
244 schema:givenName Vithanage Pujitha
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011524300234.44
246 rdf:type schema:Person
247 sg:person.012066552157.02 schema:affiliation grid-institutes:None
248 schema:familyName Kularatnam
249 schema:givenName Grace Angeline Malarnangai
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012066552157.02
251 rdf:type schema:Person
252 sg:person.012500065734.26 schema:affiliation grid-institutes:None
253 schema:familyName Samaranayake
254 schema:givenName Dulani
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012500065734.26
256 rdf:type schema:Person
257 sg:person.0725616516.28 schema:affiliation grid-institutes:grid.415115.5
258 schema:familyName Gunasena
259 schema:givenName Sunethra
260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725616516.28
261 rdf:type schema:Person
262 sg:person.0770220504.20 schema:affiliation grid-institutes:grid.415728.d
263 schema:familyName Jasinge
264 schema:givenName Eresha
265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0770220504.20
266 rdf:type schema:Person
267 sg:pub.10.1186/s12879-016-1671-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053021014
268 https://doi.org/10.1186/s12879-016-1671-3
269 rdf:type schema:CreativeWork
270 sg:pub.10.1186/s12879-018-2996-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1101179347
271 https://doi.org/10.1186/s12879-018-2996-x
272 rdf:type schema:CreativeWork
273 grid-institutes:None schema:alternateName Dehiwela, Sri Lanka
274 Department of Community Medicine, Faculty of Medicine, Colombo, Sri Lanka
275 Department of Pediatrics, Faculty of Medicine, Colombo, Sri Lanka
276 schema:name Dehiwela, Sri Lanka
277 Department of Chemical Pathology, Lady Ridgeway Hospital for children, Colombo, 08 Sri Lanka
278 Department of Community Medicine, Faculty of Medicine, Colombo, Sri Lanka
279 Department of Pediatrics, Faculty of Medicine, Colombo, Sri Lanka
280 rdf:type schema:Organization
281 grid-institutes:grid.415115.5 schema:alternateName Department of Virology, Medical Research Institute, Colombo, 08 Sri Lanka
282 schema:name Department of Virology, Medical Research Institute, Colombo, 08 Sri Lanka
283 rdf:type schema:Organization
284 grid-institutes:grid.415728.d schema:alternateName Department of Chemical Pathology, Lady Ridgeway Hospital for children, Colombo, 08 Sri Lanka
285 schema:name Department of Chemical Pathology, Lady Ridgeway Hospital for children, Colombo, 08 Sri Lanka
286 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...