Case report: bilateral Mooren ulcer in association with hepatitis C View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12-06

AUTHORS

Vesa Aaltonen, Mari Alavesa, Laura Pirilä, Eija Vesti, Mohammad Al-Juhaish

ABSTRACT

BACKGROUND: Mooren ulcer has been considered as an idiopathic autoimmune keratitis. However, it has been in some cases suggested to be associated with hepatitis C, although the evidence is very vague. CASE PRESENTATION: We present a case of a man who was diagnosed with a primary Mooren ulcer in his right eye. The eye became blind despite of intensive treatment with local medications and extensive surgical procedures. After 10 years, the patient was diagnosed with the same disease, now in his left, previously healthy eye. There was no history that would suggest a secondary Mooren ulcer, but a chronic hepatitis C infection was detected. Treatment was targeted against hepatitis C (ribavirin and interferon) in addition to immunosuppressive medical and surgical treatment which resulted in a full and more than 6 years lasting remission of the disease. CONCLUSIONS: Whether the immunomodulatory and immunosuppressive medication against hepatitis C was the key reason for the good results in the treatment of the second eye, remains elusive. The causality of hepatitis C with respect to the pathogenesis of Mooren ulcer on this patient remains open, but should be considered as one of the possible etiological factors of the disease. More... »

PAGES

239

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12886-017-0633-x

DOI

http://dx.doi.org/10.1186/s12886-017-0633-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1099699157

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29212473


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antiviral Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Conjunctival Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Corneal Ulcer", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Eye Infections, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interferon alpha-2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interferon-alpha", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polyethylene Glycols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ribavirin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Ophthalmology, University of Turku, FIN-20014 Turku, Finland", 
          "id": "http://www.grid.ac/institutes/grid.1374.1", 
          "name": [
            "Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland", 
            "Department of Ophthalmology, University of Turku, FIN-20014 Turku, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aaltonen", 
        "givenName": "Vesa", 
        "id": "sg:person.01143376703.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143376703.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland", 
          "id": "http://www.grid.ac/institutes/grid.410552.7", 
          "name": [
            "Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alavesa", 
        "givenName": "Mari", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Internal Medicine, University of Turku, FIN-20014, Turku, Finland", 
          "id": "http://www.grid.ac/institutes/grid.1374.1", 
          "name": [
            "Department of Rheumatology, Division of Medicine, Turku University Hospital, Box 52, FIN-20521 Turku, PO Finland", 
            "Department of Internal Medicine, University of Turku, FIN-20014, Turku, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Piril\u00e4", 
        "givenName": "Laura", 
        "id": "sg:person.01246356505.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246356505.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Ophthalmology, University of Turku, FIN-20014 Turku, Finland", 
          "id": "http://www.grid.ac/institutes/grid.1374.1", 
          "name": [
            "Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland", 
            "Department of Ophthalmology, University of Turku, FIN-20014 Turku, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vesti", 
        "givenName": "Eija", 
        "id": "sg:person.01165747531.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165747531.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland", 
          "id": "http://www.grid.ac/institutes/grid.410552.7", 
          "name": [
            "Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Al-Juhaish", 
        "givenName": "Mohammad", 
        "type": "Person"
      }
    ], 
    "datePublished": "2017-12-06", 
    "datePublishedReg": "2017-12-06", 
    "description": "BACKGROUND: Mooren ulcer has been considered as an idiopathic autoimmune keratitis. However, it has been in some cases suggested to be associated with hepatitis C, although the evidence is very vague.\nCASE PRESENTATION: We present a case of a man who was diagnosed with a primary Mooren ulcer in his right eye. The eye became blind despite of intensive treatment with local medications and extensive surgical procedures. After 10\u00a0years, the patient was diagnosed with the same disease, now in his left, previously healthy eye. There was no history that would suggest a secondary Mooren ulcer, but a chronic hepatitis C infection was detected. Treatment was targeted against hepatitis C (ribavirin and interferon) in addition to immunosuppressive medical and surgical treatment which resulted in a full and more than 6\u00a0years lasting remission of the disease.\nCONCLUSIONS: Whether the immunomodulatory and immunosuppressive medication against hepatitis C was the key reason for the good results in the treatment of the second eye, remains elusive. The causality of hepatitis C with respect to the pathogenesis of Mooren ulcer on this patient remains open, but should be considered as one of the possible etiological factors of the disease.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12886-017-0633-x", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024634", 
        "issn": [
          "1471-2415"
        ], 
        "name": "BMC Ophthalmology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "17"
      }
    ], 
    "keywords": [
      "Mooren's ulcer", 
      "hepatitis C", 
      "chronic hepatitis C infection", 
      "bilateral Mooren's ulcer", 
      "hepatitis C infection", 
      "extensive surgical procedures", 
      "possible etiological factors", 
      "autoimmune keratitis", 
      "immunosuppressive medications", 
      "surgical treatment", 
      "second eye", 
      "right eye", 
      "intensive treatment", 
      "healthy eyes", 
      "local medication", 
      "surgical procedures", 
      "etiological factors", 
      "ulcers", 
      "same disease", 
      "disease", 
      "medications", 
      "patients", 
      "treatment", 
      "eyes", 
      "remission", 
      "keratitis", 
      "pathogenesis", 
      "years", 
      "infection", 
      "men", 
      "cases", 
      "association", 
      "left", 
      "evidence", 
      "better results", 
      "factors", 
      "history", 
      "procedure", 
      "addition", 
      "reasons", 
      "key reason", 
      "causality", 
      "results", 
      "respect", 
      "idiopathic autoimmune keratitis", 
      "primary Mooren ulcer", 
      "secondary Mooren ulcer", 
      "C infection"
    ], 
    "name": "Case report: bilateral Mooren ulcer in association with hepatitis C", 
    "pagination": "239", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1099699157"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12886-017-0633-x"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29212473"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12886-017-0633-x", 
      "https://app.dimensions.ai/details/publication/pub.1099699157"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_733.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12886-017-0633-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12886-017-0633-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12886-017-0633-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12886-017-0633-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12886-017-0633-x'


 

This table displays all metadata directly associated to this object as RDF triples.

194 TRIPLES      21 PREDICATES      87 URIs      79 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12886-017-0633-x schema:about N007667fa8e6c4ae5a66fc39a84dc04cf
2 N060cb409525b4628a0485b22fa19edf1
3 N1444a4f3da1e411fb49a7daa0f111f8d
4 N28cda1aff65c486db5cd9caccad4b393
5 N55182d855fc246eeac50a3579549ad55
6 N7e4fc484b81a42fabe18507ea5a9a54d
7 N894e8a364c0c4130be7027e9cf9f4cd1
8 N936e6a68c059499490d5df763c63f264
9 Na03c5ace5a744fd78ece68559fe0f318
10 Na8378b87aeea425f847a32c2d49e2e23
11 Nbe6bf9eda7684676952ac31eb32b924c
12 Ndc2f99fa40a64520b8f8c7e97d2ddef2
13 Ne13276daeb7c4489a3547941b9fa7f2c
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N0738ef2b28264758bc4fcf202e89b82d
17 schema:datePublished 2017-12-06
18 schema:datePublishedReg 2017-12-06
19 schema:description BACKGROUND: Mooren ulcer has been considered as an idiopathic autoimmune keratitis. However, it has been in some cases suggested to be associated with hepatitis C, although the evidence is very vague. CASE PRESENTATION: We present a case of a man who was diagnosed with a primary Mooren ulcer in his right eye. The eye became blind despite of intensive treatment with local medications and extensive surgical procedures. After 10 years, the patient was diagnosed with the same disease, now in his left, previously healthy eye. There was no history that would suggest a secondary Mooren ulcer, but a chronic hepatitis C infection was detected. Treatment was targeted against hepatitis C (ribavirin and interferon) in addition to immunosuppressive medical and surgical treatment which resulted in a full and more than 6 years lasting remission of the disease. CONCLUSIONS: Whether the immunomodulatory and immunosuppressive medication against hepatitis C was the key reason for the good results in the treatment of the second eye, remains elusive. The causality of hepatitis C with respect to the pathogenesis of Mooren ulcer on this patient remains open, but should be considered as one of the possible etiological factors of the disease.
20 schema:genre article
21 schema:inLanguage en
22 schema:isAccessibleForFree true
23 schema:isPartOf N2d1bed86bb8146d28aca5f6f4c9a69e8
24 N9753c72118ac4ed09019f10cf65a97a5
25 sg:journal.1024634
26 schema:keywords C infection
27 Mooren's ulcer
28 addition
29 association
30 autoimmune keratitis
31 better results
32 bilateral Mooren's ulcer
33 cases
34 causality
35 chronic hepatitis C infection
36 disease
37 etiological factors
38 evidence
39 extensive surgical procedures
40 eyes
41 factors
42 healthy eyes
43 hepatitis C
44 hepatitis C infection
45 history
46 idiopathic autoimmune keratitis
47 immunosuppressive medications
48 infection
49 intensive treatment
50 keratitis
51 key reason
52 left
53 local medication
54 medications
55 men
56 pathogenesis
57 patients
58 possible etiological factors
59 primary Mooren ulcer
60 procedure
61 reasons
62 remission
63 respect
64 results
65 right eye
66 same disease
67 second eye
68 secondary Mooren ulcer
69 surgical procedures
70 surgical treatment
71 treatment
72 ulcers
73 years
74 schema:name Case report: bilateral Mooren ulcer in association with hepatitis C
75 schema:pagination 239
76 schema:productId N3f6f2fc971314043a2cbe56266a69da3
77 N9226c8b263cb42f6afc158375375d637
78 Nccaa624883a541bd82eaa87e948caace
79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099699157
80 https://doi.org/10.1186/s12886-017-0633-x
81 schema:sdDatePublished 2021-12-01T19:39
82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
83 schema:sdPublisher Na02b44d30cb54bf086f0ec2294b02407
84 schema:url https://doi.org/10.1186/s12886-017-0633-x
85 sgo:license sg:explorer/license/
86 sgo:sdDataset articles
87 rdf:type schema:ScholarlyArticle
88 N007667fa8e6c4ae5a66fc39a84dc04cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Interferon alpha-2
90 rdf:type schema:DefinedTerm
91 N060cb409525b4628a0485b22fa19edf1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Interferon-alpha
93 rdf:type schema:DefinedTerm
94 N0738ef2b28264758bc4fcf202e89b82d rdf:first sg:person.01143376703.76
95 rdf:rest Nb0060913bfe94ef0a6a5f00bb75d3553
96 N1444a4f3da1e411fb49a7daa0f111f8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Corneal Ulcer
98 rdf:type schema:DefinedTerm
99 N222dde561ebc473282af4caf471aa109 rdf:first sg:person.01165747531.43
100 rdf:rest N5626824586264b319940333031c69884
101 N28cda1aff65c486db5cd9caccad4b393 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Antiviral Agents
103 rdf:type schema:DefinedTerm
104 N2d1bed86bb8146d28aca5f6f4c9a69e8 schema:volumeNumber 17
105 rdf:type schema:PublicationVolume
106 N3f6f2fc971314043a2cbe56266a69da3 schema:name dimensions_id
107 schema:value pub.1099699157
108 rdf:type schema:PropertyValue
109 N51e2089c162f442385592e0f42e98b52 schema:affiliation grid-institutes:grid.410552.7
110 schema:familyName Alavesa
111 schema:givenName Mari
112 rdf:type schema:Person
113 N55182d855fc246eeac50a3579549ad55 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Aged
115 rdf:type schema:DefinedTerm
116 N5626824586264b319940333031c69884 rdf:first N591015cdc0994375ba12842e34f4a58c
117 rdf:rest rdf:nil
118 N591015cdc0994375ba12842e34f4a58c schema:affiliation grid-institutes:grid.410552.7
119 schema:familyName Al-Juhaish
120 schema:givenName Mohammad
121 rdf:type schema:Person
122 N7e4fc484b81a42fabe18507ea5a9a54d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Recombinant Proteins
124 rdf:type schema:DefinedTerm
125 N894e8a364c0c4130be7027e9cf9f4cd1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Ribavirin
127 rdf:type schema:DefinedTerm
128 N9226c8b263cb42f6afc158375375d637 schema:name doi
129 schema:value 10.1186/s12886-017-0633-x
130 rdf:type schema:PropertyValue
131 N936e6a68c059499490d5df763c63f264 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Male
133 rdf:type schema:DefinedTerm
134 N9753c72118ac4ed09019f10cf65a97a5 schema:issueNumber 1
135 rdf:type schema:PublicationIssue
136 Na02b44d30cb54bf086f0ec2294b02407 schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 Na03c5ace5a744fd78ece68559fe0f318 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Hepatitis C
140 rdf:type schema:DefinedTerm
141 Na8378b87aeea425f847a32c2d49e2e23 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Eye Infections, Viral
143 rdf:type schema:DefinedTerm
144 Nb0060913bfe94ef0a6a5f00bb75d3553 rdf:first N51e2089c162f442385592e0f42e98b52
145 rdf:rest Nd2d0cd93258f48748d7ca194416ae85f
146 Nbe6bf9eda7684676952ac31eb32b924c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Polyethylene Glycols
148 rdf:type schema:DefinedTerm
149 Nccaa624883a541bd82eaa87e948caace schema:name pubmed_id
150 schema:value 29212473
151 rdf:type schema:PropertyValue
152 Nd2d0cd93258f48748d7ca194416ae85f rdf:first sg:person.01246356505.48
153 rdf:rest N222dde561ebc473282af4caf471aa109
154 Ndc2f99fa40a64520b8f8c7e97d2ddef2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Humans
156 rdf:type schema:DefinedTerm
157 Ne13276daeb7c4489a3547941b9fa7f2c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Conjunctival Diseases
159 rdf:type schema:DefinedTerm
160 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
161 schema:name Medical and Health Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
164 schema:name Clinical Sciences
165 rdf:type schema:DefinedTerm
166 sg:journal.1024634 schema:issn 1471-2415
167 schema:name BMC Ophthalmology
168 schema:publisher Springer Nature
169 rdf:type schema:Periodical
170 sg:person.01143376703.76 schema:affiliation grid-institutes:grid.1374.1
171 schema:familyName Aaltonen
172 schema:givenName Vesa
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143376703.76
174 rdf:type schema:Person
175 sg:person.01165747531.43 schema:affiliation grid-institutes:grid.1374.1
176 schema:familyName Vesti
177 schema:givenName Eija
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165747531.43
179 rdf:type schema:Person
180 sg:person.01246356505.48 schema:affiliation grid-institutes:grid.1374.1
181 schema:familyName Pirilä
182 schema:givenName Laura
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246356505.48
184 rdf:type schema:Person
185 grid-institutes:grid.1374.1 schema:alternateName Department of Internal Medicine, University of Turku, FIN-20014, Turku, Finland
186 Department of Ophthalmology, University of Turku, FIN-20014 Turku, Finland
187 schema:name Department of Internal Medicine, University of Turku, FIN-20014, Turku, Finland
188 Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland
189 Department of Ophthalmology, University of Turku, FIN-20014 Turku, Finland
190 Department of Rheumatology, Division of Medicine, Turku University Hospital, Box 52, FIN-20521 Turku, PO Finland
191 rdf:type schema:Organization
192 grid-institutes:grid.410552.7 schema:alternateName Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland
193 schema:name Department of Ophthalmology, Turku University Hospital, PO Box 52, FIN-20521 Turku, Finland
194 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...