The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-12

AUTHORS

Rainer J. Klement, N. Abbasi-Senger, S. Adebahr, H. Alheid, M. Allgaeuer, G. Becker, O. Blanck, J. Boda-Heggemann, T. Brunner, M. Duma, M. J. Eble, I. Ernst, S. Gerum, D. Habermehl, P. Hass, C. Henkenberens, G. Hildebrandt, D. Imhoff, H. Kahl, N. D. Klass, R. Krempien, V. Lewitzki, F. Lohaus, C. Ostheimer, A. Papachristofilou, C. Petersen, J. Rieber, T. Schneider, E. Schrade, R. Semrau, S. Wachter, A. Wittig, M. Guckenberger, N. Andratschke

ABSTRACT

BACKGROUND: The aim of this analysis was to model the effect of local control (LC) on overall survival (OS) in patients treated with stereotactic body radiotherapy (SBRT) for liver or lung metastases from colorectal cancer. METHODS: The analysis is based on pooled data from two retrospective SBRT databases for pulmonary and hepatic metastases from 27 centers from Germany and Switzerland. Only patients with metastases from colorectal cancer were considered to avoid histology as a confounding factor. An illness-death model was employed to model the relationship between LC and OS. RESULTS: Three hundred eighty-eight patients with 500 metastatic lesions (lung n = 209, liver n = 291) were included and analyzed. Median follow-up time for local recurrence assessment was 12.1 months. Ninety-nine patients with 112 lesions experienced local failure. Seventy-one of these patients died after local failure. Median survival time was 27.9 months in all patients and 25.4 months versus 30.6 months in patients with and without local failure after SBRT. The baseline risk of death after local failure exceeds the baseline risk of death without local failure at 10 months indicating better survival with LC. CONCLUSION: In CRC patients with lung or liver metastases, our findings suggest improved long-term OS by achieving metastatic disease control using SBRT in patients with a projected OS estimate of > 12 months. More... »

PAGES

173

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12885-019-5362-5

DOI

http://dx.doi.org/10.1186/s12885-019-5362-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112391663

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30808323


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Leopoldina Hospital Schweinfurt, Schweinfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klement", 
        "givenName": "Rainer J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jena University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.275559.9", 
          "name": [
            "Department of Radiation Oncology, University Hospital Jena, Jena, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abbasi-Senger", 
        "givenName": "N.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, University Hospital Freiburg, Freiburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Adebahr", 
        "givenName": "S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Strahlentherapie Bautzen, Bautzen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alheid", 
        "givenName": "H.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Hospital Barmherzige Brueder, Regensburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Allgaeuer", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "RadioChirurgicum CyberKnife Suedwest, Goeppingen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Becker", 
        "givenName": "G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology Universitaetsklinikum Schleswig-Holstein, Luebeck, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Blanck", 
        "givenName": "O.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Centre Mannheim", 
          "id": "https://www.grid.ac/institutes/grid.411778.c", 
          "name": [
            "Department of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Boda-Heggemann", 
        "givenName": "J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, University Hospital Freiburg, Freiburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Brunner", 
        "givenName": "T.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Technical University Munich", 
          "id": "https://www.grid.ac/institutes/grid.6936.a", 
          "name": [
            "Department of Radiation Oncology, Klinikum rechts der Isar- Technische Universitaet Muenchen, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Duma", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e4tsklinikum Aachen", 
          "id": "https://www.grid.ac/institutes/grid.412301.5", 
          "name": [
            "Department of Radiation Oncology, University Hospital Aachen, Aachen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eble", 
        "givenName": "M. J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital M\u00fcnster", 
          "id": "https://www.grid.ac/institutes/grid.16149.3b", 
          "name": [
            "Department of Radiation Oncology, University Hospital Muenster, Muenster, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ernst", 
        "givenName": "I.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ludwig Maximilian University of Munich", 
          "id": "https://www.grid.ac/institutes/grid.5252.0", 
          "name": [
            "Department of Radiation Oncology, Ludwig Maximilians University Munich, Munich, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gerum", 
        "givenName": "S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Heidelberg", 
          "id": "https://www.grid.ac/institutes/grid.5253.1", 
          "name": [
            "Department of Radiation Oncology, Klinikum rechts der Isar- Technische Universitaet Muenchen, Munich, Germany", 
            "Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Habermehl", 
        "givenName": "D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universit\u00e4tsaugenklinik Magdeburg", 
          "id": "https://www.grid.ac/institutes/grid.488575.3", 
          "name": [
            "Department of Radiation Oncology, University Hospital Magdeburg, Magdeburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hass", 
        "givenName": "P.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hannover Medical School", 
          "id": "https://www.grid.ac/institutes/grid.10423.34", 
          "name": [
            "Department of Radiotherapy and Special Oncology, Medical School Hannover, Hanover, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Henkenberens", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Rostock", 
          "id": "https://www.grid.ac/institutes/grid.10493.3f", 
          "name": [
            "Department of Radiation Oncology, University of Rostock, Rostock, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hildebrandt", 
        "givenName": "G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.411088.4", 
          "name": [
            "Department of Radiation Oncology, University Hospital Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imhoff", 
        "givenName": "D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Hospital Augsburg, Augsburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kahl", 
        "givenName": "H.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Children\u2019s Hospital Bern", 
          "id": "https://www.grid.ac/institutes/grid.412353.2", 
          "name": [
            "Department of Radiation Oncology, University Hospital Bern, Bern, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klass", 
        "givenName": "N. D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Helios Hospital Berlin-Buch", 
          "id": "https://www.grid.ac/institutes/grid.491869.b", 
          "name": [
            "Department of Radiation Oncology, Helios Klinikum Berlin Buch, Berlin, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Krempien", 
        "givenName": "R.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital of W\u00fcrzburg", 
          "id": "https://www.grid.ac/institutes/grid.411760.5", 
          "name": [
            "Department of Radiation Oncology, University Hospital Wuerzburg, Wuerzburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lewitzki", 
        "givenName": "V.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "TU Dresden", 
          "id": "https://www.grid.ac/institutes/grid.4488.0", 
          "name": [
            "Department of Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lohaus", 
        "givenName": "F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital in Halle", 
          "id": "https://www.grid.ac/institutes/grid.461820.9", 
          "name": [
            "Department of Radiation Oncology, University Hospital Halle, Halle, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ostheimer", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Hamburg-Eppendorf", 
          "id": "https://www.grid.ac/institutes/grid.13648.38", 
          "name": [
            "Department of Radiation Oncology, University Hospital Hamburg, Hamburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Papachristofilou", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital of Basel", 
          "id": "https://www.grid.ac/institutes/grid.410567.1", 
          "name": [
            "Department of Radiation Oncology, University Hospital Basel, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Petersen", 
        "givenName": "C.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Heidelberg", 
          "id": "https://www.grid.ac/institutes/grid.5253.1", 
          "name": [
            "Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rieber", 
        "givenName": "J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Strahlenzentrum Hamburg, Hamburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schneider", 
        "givenName": "T.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Hospital Heidenheim, Heidenheim, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schrade", 
        "givenName": "E.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Cologne", 
          "id": "https://www.grid.ac/institutes/grid.411097.a", 
          "name": [
            "Department of Radiation Oncology, University Hospital of Cologne, Cologne, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Semrau", 
        "givenName": "R.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Klinikum Passau, Passau, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wachter", 
        "givenName": "S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Philipp University of Marburg", 
          "id": "https://www.grid.ac/institutes/grid.10253.35", 
          "name": [
            "Department of Radiation Oncology, University Hospital Jena, Jena, Germany", 
            "Department of Radiotherapy and Radiation Oncology, Philipps-University Marburg, University Hospital Giessen and Marburg, Marburg, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wittig", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, University Hospital Zurich, University of Zurich, R\u00e4mistrasse 100, 8091, Zurich, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guckenberger", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, University Hospital Zurich, University of Zurich, R\u00e4mistrasse 100, 8091, Zurich, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Andratschke", 
        "givenName": "N.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1003743887", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1003743887", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(16)30532-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003744409"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02841860600908954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004720951"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lungcan.2016.04.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006150079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2015.01.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006208082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31826b4dcc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011154183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e31826b4dcc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011154183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2011.08.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017514898"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.19.6329", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017605315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2015.12.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017840149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13014-016-0652-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018446824", 
          "https://doi.org/10.1186/s13014-016-0652-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02698590701498084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024621176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2016.03.050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026081815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1477-7819-12-127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028337829", 
          "https://doi.org/10.1186/1477-7819-12-127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gutjnl-2015-310912", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029185920"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/02841860600904821", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030251382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jso.21102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031739276"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clon.2014.06.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034580904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2006.10.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034766080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/sim.3107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035287200"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jto.0b013e3182208e58", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035497536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.19.6386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041129418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2011.05.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042497797"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-010-1187-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047420379", 
          "https://doi.org/10.1245/s10434-010-1187-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-010-1187-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047420379", 
          "https://doi.org/10.1245/s10434-010-1187-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1541-0420.2009.01340.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052300072"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.26611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052457938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199909000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060135098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199909000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060135098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-199909000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060135098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.115.001841", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063343662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.115.001841", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063343662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18637/jss.v045.i03", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068672674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18637/jss.v047.i04", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068672704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3978/j.issn.2072-1439.2013.12.03", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078889080"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1995.13.1.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082512517"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007611-199301000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082799417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007611-199301000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082799417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007611-199301000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082799417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2017.01.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083544247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/djx015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083932849"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2017.01.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084104846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.radonc.2017.03.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084104874"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-12", 
    "datePublishedReg": "2019-12-01", 
    "description": "BACKGROUND: The aim of this analysis was to model the effect of local control (LC) on overall survival (OS) in patients treated with stereotactic body radiotherapy (SBRT) for liver or lung metastases from colorectal cancer.\nMETHODS: The analysis is based on pooled data from two retrospective SBRT databases for pulmonary and hepatic metastases from 27 centers from Germany and Switzerland. Only patients with metastases from colorectal cancer were considered to avoid histology as a confounding factor. An illness-death model was employed to model the relationship between LC and OS.\nRESULTS: Three hundred eighty-eight patients with 500 metastatic lesions (lung n\u2009=\u2009209, liver n\u2009=\u2009291) were included and analyzed. Median follow-up time for local recurrence assessment was 12.1\u2009months. Ninety-nine patients with 112 lesions experienced local failure. Seventy-one of these patients died after local failure. Median survival time was 27.9\u2009months in all patients and 25.4\u2009months versus 30.6\u2009months in patients with and without local failure after SBRT. The baseline risk of death after local failure exceeds the baseline risk of death without local failure at 10\u2009months indicating better survival with LC.\nCONCLUSION: In CRC patients with lung or liver metastases, our findings suggest improved long-term OS by achieving metastatic disease control using SBRT in patients with a projected OS estimate of >\u200912\u2009months.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12885-019-5362-5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024632", 
        "issn": [
          "1471-2407"
        ], 
        "name": "BMC Cancer", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "name": "The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases", 
    "pagination": "173", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5c8c7754062e6876639d13c575d7621b295efb67c155ae9634c01cb580ddf938"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30808323"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100967800"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12885-019-5362-5"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112391663"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12885-019-5362-5", 
      "https://app.dimensions.ai/details/publication/pub.1112391663"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:17", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000368_0000000368/records_78934_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12885-019-5362-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12885-019-5362-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12885-019-5362-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12885-019-5362-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12885-019-5362-5'


 

This table displays all metadata directly associated to this object as RDF triples.

460 TRIPLES      21 PREDICATES      65 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12885-019-5362-5 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N3515879c70e04ec4b1ccd85763825ac3
4 schema:citation sg:pub.10.1186/1477-7819-12-127
5 sg:pub.10.1186/s13014-016-0652-4
6 sg:pub.10.1245/s10434-010-1187-9
7 https://app.dimensions.ai/details/publication/pub.1003743887
8 https://doi.org/10.1002/cncr.26611
9 https://doi.org/10.1002/jso.21102
10 https://doi.org/10.1002/sim.3107
11 https://doi.org/10.1016/j.clon.2014.06.018
12 https://doi.org/10.1016/j.ijrobp.2006.10.025
13 https://doi.org/10.1016/j.ijrobp.2011.08.036
14 https://doi.org/10.1016/j.ijrobp.2015.01.036
15 https://doi.org/10.1016/j.ijrobp.2015.12.004
16 https://doi.org/10.1016/j.ijrobp.2016.03.050
17 https://doi.org/10.1016/j.lungcan.2016.04.012
18 https://doi.org/10.1016/j.radonc.2011.05.033
19 https://doi.org/10.1016/j.radonc.2017.01.003
20 https://doi.org/10.1016/j.radonc.2017.01.013
21 https://doi.org/10.1016/j.radonc.2017.03.014
22 https://doi.org/10.1016/s1470-2045(16)30532-0
23 https://doi.org/10.1080/02698590701498084
24 https://doi.org/10.1080/02841860600904821
25 https://doi.org/10.1080/02841860600908954
26 https://doi.org/10.1093/jnci/djx015
27 https://doi.org/10.1097/00000658-199909000-00004
28 https://doi.org/10.1097/00007611-199301000-00009
29 https://doi.org/10.1097/jto.0b013e3182208e58
30 https://doi.org/10.1097/sla.0b013e31826b4dcc
31 https://doi.org/10.1111/j.1541-0420.2009.01340.x
32 https://doi.org/10.1136/gutjnl-2015-310912
33 https://doi.org/10.1161/circoutcomes.115.001841
34 https://doi.org/10.1200/jco.1995.13.1.8
35 https://doi.org/10.1200/jco.2008.19.6329
36 https://doi.org/10.1200/jco.2008.19.6386
37 https://doi.org/10.18637/jss.v045.i03
38 https://doi.org/10.18637/jss.v047.i04
39 https://doi.org/10.3978/j.issn.2072-1439.2013.12.03
40 schema:datePublished 2019-12
41 schema:datePublishedReg 2019-12-01
42 schema:description BACKGROUND: The aim of this analysis was to model the effect of local control (LC) on overall survival (OS) in patients treated with stereotactic body radiotherapy (SBRT) for liver or lung metastases from colorectal cancer. METHODS: The analysis is based on pooled data from two retrospective SBRT databases for pulmonary and hepatic metastases from 27 centers from Germany and Switzerland. Only patients with metastases from colorectal cancer were considered to avoid histology as a confounding factor. An illness-death model was employed to model the relationship between LC and OS. RESULTS: Three hundred eighty-eight patients with 500 metastatic lesions (lung n = 209, liver n = 291) were included and analyzed. Median follow-up time for local recurrence assessment was 12.1 months. Ninety-nine patients with 112 lesions experienced local failure. Seventy-one of these patients died after local failure. Median survival time was 27.9 months in all patients and 25.4 months versus 30.6 months in patients with and without local failure after SBRT. The baseline risk of death after local failure exceeds the baseline risk of death without local failure at 10 months indicating better survival with LC. CONCLUSION: In CRC patients with lung or liver metastases, our findings suggest improved long-term OS by achieving metastatic disease control using SBRT in patients with a projected OS estimate of > 12 months.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree true
46 schema:isPartOf N5c3a56c0f5d24cdda8514665464d1f78
47 N9ae1119ebb47444092b2a153fac15c47
48 sg:journal.1024632
49 schema:name The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases
50 schema:pagination 173
51 schema:productId N1bf201612cd54977a8ca5f35066ca998
52 N57781bec02be44538045bfbee2c23220
53 N71b3750d7471467ba399c0dd8450497d
54 N7ef1b8d91ef149a4a674bc78254e9878
55 Ndb5376523e2b456d9b180ff7656a1c6b
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112391663
57 https://doi.org/10.1186/s12885-019-5362-5
58 schema:sdDatePublished 2019-04-11T13:17
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher Ndeb3639ffae44ecaa549232d3b0ae16c
61 schema:url https://link.springer.com/10.1186%2Fs12885-019-5362-5
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N02f6a19f9f134dcca52d079b02d8d883 schema:name Strahlentherapie Bautzen, Bautzen, Germany
66 rdf:type schema:Organization
67 N06a8fe0cb3c24d9bae1e51ab8d96d60a schema:name Department of Radiation Oncology, University Hospital Freiburg, Freiburg, Germany
68 rdf:type schema:Organization
69 N06c12d3475934f95b0ff5505a5813f19 schema:affiliation https://www.grid.ac/institutes/grid.10493.3f
70 schema:familyName Hildebrandt
71 schema:givenName G.
72 rdf:type schema:Person
73 N0c6acefc91ea44518b152f5f96f0ac14 rdf:first Nd779f3e663084cff851d992d79117c28
74 rdf:rest Nabeb2fa441084fdf9268aaa36e082bf3
75 N0e1498472f69456585c84d9b30d81db7 rdf:first N6aa96dd796ce4f9caf85f0967c4ddcda
76 rdf:rest Nfdbbb33092204dbaacd3ef5fa7bcc4e5
77 N145e308a614a404c816e1c47b7be1d38 rdf:first N1bf6d93220b0417e9cd44c8e284e7207
78 rdf:rest N5e7be2590a194f1b91687bf2776283c6
79 N1617f5fea5a64558b52d3d33f850dafc schema:affiliation N06a8fe0cb3c24d9bae1e51ab8d96d60a
80 schema:familyName Adebahr
81 schema:givenName S.
82 rdf:type schema:Person
83 N1970d97e6f7e4b61a15910324710f1fa schema:affiliation https://www.grid.ac/institutes/grid.412353.2
84 schema:familyName Klass
85 schema:givenName N. D.
86 rdf:type schema:Person
87 N19d8ae8919c34ad494693db31e5a5106 rdf:first Na649730b2f284e9a8000e75b70a68555
88 rdf:rest N9bbf8cf5529744f19c7010bc2c359d67
89 N1af3f993745b4364b0e6f834d0144651 schema:affiliation https://www.grid.ac/institutes/grid.13648.38
90 schema:familyName Papachristofilou
91 schema:givenName A.
92 rdf:type schema:Person
93 N1bf201612cd54977a8ca5f35066ca998 schema:name dimensions_id
94 schema:value pub.1112391663
95 rdf:type schema:PropertyValue
96 N1bf6d93220b0417e9cd44c8e284e7207 schema:affiliation https://www.grid.ac/institutes/grid.461820.9
97 schema:familyName Ostheimer
98 schema:givenName C.
99 rdf:type schema:Person
100 N1d247f33e08046dd8641d1abcb7e92d4 schema:affiliation https://www.grid.ac/institutes/grid.491869.b
101 schema:familyName Krempien
102 schema:givenName R.
103 rdf:type schema:Person
104 N1f13a42264d546628474d76fe7604530 schema:affiliation https://www.grid.ac/institutes/grid.411088.4
105 schema:familyName Imhoff
106 schema:givenName D.
107 rdf:type schema:Person
108 N2a6ab59034eb4d28b56e2407d4fe749c schema:affiliation https://www.grid.ac/institutes/grid.5253.1
109 schema:familyName Rieber
110 schema:givenName J.
111 rdf:type schema:Person
112 N2b243a3fa4484d2ca8b69167feb85f8d rdf:first N1d247f33e08046dd8641d1abcb7e92d4
113 rdf:rest N0e1498472f69456585c84d9b30d81db7
114 N348a871d6a4d452fb39018ceed6d9328 schema:affiliation https://www.grid.ac/institutes/grid.412301.5
115 schema:familyName Eble
116 schema:givenName M. J.
117 rdf:type schema:Person
118 N3515879c70e04ec4b1ccd85763825ac3 rdf:first N3821d9a2eaef4570be6753e531c56b1d
119 rdf:rest Ned1c12fce89547d5b9203b1bea052e30
120 N35b1704d13f7456781e8c4f132738af5 schema:affiliation N596fa39842a64134ae1ccc4c16ad5ed5
121 schema:familyName Allgaeuer
122 schema:givenName M.
123 rdf:type schema:Person
124 N35c6fb4b09c04c258b77092597bb3890 rdf:first N902ede68ff0348d382dfdff348d0505e
125 rdf:rest rdf:nil
126 N3821d9a2eaef4570be6753e531c56b1d schema:affiliation Nd3d0b76314454e21b2b49025b5bcf853
127 schema:familyName Klement
128 schema:givenName Rainer J.
129 rdf:type schema:Person
130 N39f25f02d47d48afbead7ce33e215591 rdf:first N1617f5fea5a64558b52d3d33f850dafc
131 rdf:rest Nec5fe75135fb4bc8bb4070f74502b6bc
132 N3e271711235240f782c9e62ab2f099e9 schema:affiliation https://www.grid.ac/institutes/grid.5252.0
133 schema:familyName Gerum
134 schema:givenName S.
135 rdf:type schema:Person
136 N417bb1cbabc945e483ebb55b39a03387 schema:affiliation https://www.grid.ac/institutes/grid.4488.0
137 schema:familyName Lohaus
138 schema:givenName F.
139 rdf:type schema:Person
140 N44d4f2a2d09c4f9ca0b18224c98a6d11 schema:name RadioChirurgicum CyberKnife Suedwest, Goeppingen, Germany
141 rdf:type schema:Organization
142 N461deaee25a147a897baecff03d662b2 schema:affiliation https://www.grid.ac/institutes/grid.16149.3b
143 schema:familyName Ernst
144 schema:givenName I.
145 rdf:type schema:Person
146 N4689131308cf49a0a526f00ed98f6d93 rdf:first Nac6295341e54467c8c8266e5423ef5e5
147 rdf:rest N7b10f627cf4e4f5993ad0bd6966b4935
148 N48a095f5c0ed450c8289358ed7d93c03 schema:affiliation Na81d5ec1f2f449d7b4ed4bbe3f1e73c0
149 schema:familyName Brunner
150 schema:givenName T.
151 rdf:type schema:Person
152 N518484465e2741e2803e4efa0dc20d24 schema:name Department of Radiation Oncology, Klinikum Passau, Passau, Germany
153 rdf:type schema:Organization
154 N52d9bc07ead447959b5e4fcd5d4da6cd rdf:first Ncd18fb7d3b4747d1b304ebd52bbd3a31
155 rdf:rest N9a8bfcce3260400492387fcc393fbdda
156 N57781bec02be44538045bfbee2c23220 schema:name pubmed_id
157 schema:value 30808323
158 rdf:type schema:PropertyValue
159 N588331a3ce0644e9906a4a45fdade8dd rdf:first N6c25c989c03c410e86c6683b0e63875e
160 rdf:rest Nde101f373ff44014b862ad7f36533565
161 N596fa39842a64134ae1ccc4c16ad5ed5 schema:name Department of Radiation Oncology, Hospital Barmherzige Brueder, Regensburg, Germany
162 rdf:type schema:Organization
163 N5c3a56c0f5d24cdda8514665464d1f78 schema:volumeNumber 19
164 rdf:type schema:PublicationVolume
165 N5e762b0b7d9a4123925438416c9e6a25 schema:affiliation https://www.grid.ac/institutes/grid.6936.a
166 schema:familyName Duma
167 schema:givenName M.
168 rdf:type schema:Person
169 N5e7be2590a194f1b91687bf2776283c6 rdf:first N1af3f993745b4364b0e6f834d0144651
170 rdf:rest N0c6acefc91ea44518b152f5f96f0ac14
171 N5f4d85b3de804439ace124a0bcd39294 rdf:first N1f13a42264d546628474d76fe7604530
172 rdf:rest Nd1b8372e366041bb8a2dd2a230d625f6
173 N6938809074504754a44ec67aea0dfa7d schema:name Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland
174 rdf:type schema:Organization
175 N6a816a62c89044f09dc30af49d43c0f1 rdf:first N461deaee25a147a897baecff03d662b2
176 rdf:rest Ne4a360f3a6584a8e8db308bae40e1a9e
177 N6aa96dd796ce4f9caf85f0967c4ddcda schema:affiliation https://www.grid.ac/institutes/grid.411760.5
178 schema:familyName Lewitzki
179 schema:givenName V.
180 rdf:type schema:Person
181 N6bfa5cfeb3b54056b349a9ad27b79dcf schema:affiliation N6938809074504754a44ec67aea0dfa7d
182 schema:familyName Guckenberger
183 schema:givenName M.
184 rdf:type schema:Person
185 N6c25c989c03c410e86c6683b0e63875e schema:affiliation https://www.grid.ac/institutes/grid.5253.1
186 schema:familyName Habermehl
187 schema:givenName D.
188 rdf:type schema:Person
189 N71b3750d7471467ba399c0dd8450497d schema:name readcube_id
190 schema:value 5c8c7754062e6876639d13c575d7621b295efb67c155ae9634c01cb580ddf938
191 rdf:type schema:PropertyValue
192 N72a4dc63d52d40f981a1efacad89d77a rdf:first N06c12d3475934f95b0ff5505a5813f19
193 rdf:rest N5f4d85b3de804439ace124a0bcd39294
194 N7412d71fe2e14bb8971154812a0ac16e schema:affiliation Nb0a20ae843dc46f59ac01e548e2f09f2
195 schema:familyName Kahl
196 schema:givenName H.
197 rdf:type schema:Person
198 N790a6a39b86f4704b8b55d0ee7fdc3ed rdf:first N35b1704d13f7456781e8c4f132738af5
199 rdf:rest N7ee1de8653144da59244edd6bf870024
200 N795ec1355f6e43738f5e84416b8dcc92 schema:affiliation https://www.grid.ac/institutes/grid.10423.34
201 schema:familyName Henkenberens
202 schema:givenName C.
203 rdf:type schema:Person
204 N7b10f627cf4e4f5993ad0bd6966b4935 rdf:first Ndef20a1d76b34b0a854ebfe22da07140
205 rdf:rest N90c53d0f983340ce8c487f8b3c00ef88
206 N7ee1de8653144da59244edd6bf870024 rdf:first Nec82b92d27b14cfd96f81d9fb5804fb7
207 rdf:rest Nf0dbf901fad64a4fa513a41d4546dba0
208 N7ef1b8d91ef149a4a674bc78254e9878 schema:name nlm_unique_id
209 schema:value 100967800
210 rdf:type schema:PropertyValue
211 N81bfdb1cbd254837b705e86495d06896 schema:name Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland
212 rdf:type schema:Organization
213 N890033a3cfc3446483ccaf68661314b8 schema:name Strahlenzentrum Hamburg, Hamburg, Germany
214 rdf:type schema:Organization
215 N8d363e8272824f57a32c05ede3c3c116 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
216 schema:familyName Semrau
217 schema:givenName R.
218 rdf:type schema:Person
219 N902ede68ff0348d382dfdff348d0505e schema:affiliation N81bfdb1cbd254837b705e86495d06896
220 schema:familyName Andratschke
221 schema:givenName N.
222 rdf:type schema:Person
223 N90c53d0f983340ce8c487f8b3c00ef88 rdf:first N8d363e8272824f57a32c05ede3c3c116
224 rdf:rest Nffa364393fef4c868b716edfacb5a70d
225 N914d90eb66804997b2f914445d874467 schema:name Department of Radiation Oncology, Hospital Heidenheim, Heidenheim, Germany
226 rdf:type schema:Organization
227 N980bf6a79272455e9b720b5d69933270 schema:affiliation https://www.grid.ac/institutes/grid.488575.3
228 schema:familyName Hass
229 schema:givenName P.
230 rdf:type schema:Person
231 N9a8bfcce3260400492387fcc393fbdda rdf:first N6bfa5cfeb3b54056b349a9ad27b79dcf
232 rdf:rest N35c6fb4b09c04c258b77092597bb3890
233 N9ae1119ebb47444092b2a153fac15c47 schema:issueNumber 1
234 rdf:type schema:PublicationIssue
235 N9bbf8cf5529744f19c7010bc2c359d67 rdf:first N48a095f5c0ed450c8289358ed7d93c03
236 rdf:rest Nacdb49a9c88147a8b3ca33384da565ba
237 N9c5ca1e9b8324e4b8fc15437256fd957 schema:affiliation https://www.grid.ac/institutes/grid.275559.9
238 schema:familyName Abbasi-Senger
239 schema:givenName N.
240 rdf:type schema:Person
241 N9f7e51264f0b4bcaa3051e74815fafba schema:name Department of Radiation Oncology Universitaetsklinikum Schleswig-Holstein, Luebeck, Germany
242 rdf:type schema:Organization
243 Na649730b2f284e9a8000e75b70a68555 schema:affiliation https://www.grid.ac/institutes/grid.411778.c
244 schema:familyName Boda-Heggemann
245 schema:givenName J.
246 rdf:type schema:Person
247 Na81d5ec1f2f449d7b4ed4bbe3f1e73c0 schema:name Department of Radiation Oncology, University Hospital Freiburg, Freiburg, Germany
248 rdf:type schema:Organization
249 Nabeb2fa441084fdf9268aaa36e082bf3 rdf:first N2a6ab59034eb4d28b56e2407d4fe749c
250 rdf:rest N4689131308cf49a0a526f00ed98f6d93
251 Nac6295341e54467c8c8266e5423ef5e5 schema:affiliation N890033a3cfc3446483ccaf68661314b8
252 schema:familyName Schneider
253 schema:givenName T.
254 rdf:type schema:Person
255 Nacdb49a9c88147a8b3ca33384da565ba rdf:first N5e762b0b7d9a4123925438416c9e6a25
256 rdf:rest Nb789da8416d04ca89628633f31185d91
257 Nb0a20ae843dc46f59ac01e548e2f09f2 schema:name Department of Radiation Oncology, Hospital Augsburg, Augsburg, Germany
258 rdf:type schema:Organization
259 Nb789da8416d04ca89628633f31185d91 rdf:first N348a871d6a4d452fb39018ceed6d9328
260 rdf:rest N6a816a62c89044f09dc30af49d43c0f1
261 Nbd40c2b704bf47c08b23163d77df8151 rdf:first N1970d97e6f7e4b61a15910324710f1fa
262 rdf:rest N2b243a3fa4484d2ca8b69167feb85f8d
263 Nbd6b84c81258485f9a1b344436592065 schema:affiliation N02f6a19f9f134dcca52d079b02d8d883
264 schema:familyName Alheid
265 schema:givenName H.
266 rdf:type schema:Person
267 Ncd18fb7d3b4747d1b304ebd52bbd3a31 schema:affiliation https://www.grid.ac/institutes/grid.10253.35
268 schema:familyName Wittig
269 schema:givenName A.
270 rdf:type schema:Person
271 Nd1b8372e366041bb8a2dd2a230d625f6 rdf:first N7412d71fe2e14bb8971154812a0ac16e
272 rdf:rest Nbd40c2b704bf47c08b23163d77df8151
273 Nd3d0b76314454e21b2b49025b5bcf853 schema:name Department of Radiation Oncology, Leopoldina Hospital Schweinfurt, Schweinfurt, Germany
274 rdf:type schema:Organization
275 Nd779f3e663084cff851d992d79117c28 schema:affiliation https://www.grid.ac/institutes/grid.410567.1
276 schema:familyName Petersen
277 schema:givenName C.
278 rdf:type schema:Person
279 Ndb5376523e2b456d9b180ff7656a1c6b schema:name doi
280 schema:value 10.1186/s12885-019-5362-5
281 rdf:type schema:PropertyValue
282 Nde101f373ff44014b862ad7f36533565 rdf:first N980bf6a79272455e9b720b5d69933270
283 rdf:rest Nf637d7d4b5884004bfb9ae917e453d2b
284 Ndeb3639ffae44ecaa549232d3b0ae16c schema:name Springer Nature - SN SciGraph project
285 rdf:type schema:Organization
286 Ndef20a1d76b34b0a854ebfe22da07140 schema:affiliation N914d90eb66804997b2f914445d874467
287 schema:familyName Schrade
288 schema:givenName E.
289 rdf:type schema:Person
290 Ndfbcf4196b84485e8077a8ea98f3a84f schema:affiliation N518484465e2741e2803e4efa0dc20d24
291 schema:familyName Wachter
292 schema:givenName S.
293 rdf:type schema:Person
294 Ne4a360f3a6584a8e8db308bae40e1a9e rdf:first N3e271711235240f782c9e62ab2f099e9
295 rdf:rest N588331a3ce0644e9906a4a45fdade8dd
296 Nec5fe75135fb4bc8bb4070f74502b6bc rdf:first Nbd6b84c81258485f9a1b344436592065
297 rdf:rest N790a6a39b86f4704b8b55d0ee7fdc3ed
298 Nec82b92d27b14cfd96f81d9fb5804fb7 schema:affiliation N44d4f2a2d09c4f9ca0b18224c98a6d11
299 schema:familyName Becker
300 schema:givenName G.
301 rdf:type schema:Person
302 Ned1c12fce89547d5b9203b1bea052e30 rdf:first N9c5ca1e9b8324e4b8fc15437256fd957
303 rdf:rest N39f25f02d47d48afbead7ce33e215591
304 Nf0dbf901fad64a4fa513a41d4546dba0 rdf:first Nfab0ebb46ff546b6b18903cfabf09d56
305 rdf:rest N19d8ae8919c34ad494693db31e5a5106
306 Nf637d7d4b5884004bfb9ae917e453d2b rdf:first N795ec1355f6e43738f5e84416b8dcc92
307 rdf:rest N72a4dc63d52d40f981a1efacad89d77a
308 Nfab0ebb46ff546b6b18903cfabf09d56 schema:affiliation N9f7e51264f0b4bcaa3051e74815fafba
309 schema:familyName Blanck
310 schema:givenName O.
311 rdf:type schema:Person
312 Nfdbbb33092204dbaacd3ef5fa7bcc4e5 rdf:first N417bb1cbabc945e483ebb55b39a03387
313 rdf:rest N145e308a614a404c816e1c47b7be1d38
314 Nffa364393fef4c868b716edfacb5a70d rdf:first Ndfbcf4196b84485e8077a8ea98f3a84f
315 rdf:rest N52d9bc07ead447959b5e4fcd5d4da6cd
316 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
317 schema:name Medical and Health Sciences
318 rdf:type schema:DefinedTerm
319 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
320 schema:name Oncology and Carcinogenesis
321 rdf:type schema:DefinedTerm
322 sg:journal.1024632 schema:issn 1471-2407
323 schema:name BMC Cancer
324 rdf:type schema:Periodical
325 sg:pub.10.1186/1477-7819-12-127 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028337829
326 https://doi.org/10.1186/1477-7819-12-127
327 rdf:type schema:CreativeWork
328 sg:pub.10.1186/s13014-016-0652-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018446824
329 https://doi.org/10.1186/s13014-016-0652-4
330 rdf:type schema:CreativeWork
331 sg:pub.10.1245/s10434-010-1187-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047420379
332 https://doi.org/10.1245/s10434-010-1187-9
333 rdf:type schema:CreativeWork
334 https://app.dimensions.ai/details/publication/pub.1003743887 schema:CreativeWork
335 https://doi.org/10.1002/cncr.26611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052457938
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1002/jso.21102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031739276
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1002/sim.3107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035287200
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1016/j.clon.2014.06.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034580904
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1016/j.ijrobp.2006.10.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034766080
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1016/j.ijrobp.2011.08.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017514898
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1016/j.ijrobp.2015.01.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006208082
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1016/j.ijrobp.2015.12.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017840149
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1016/j.ijrobp.2016.03.050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026081815
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1016/j.lungcan.2016.04.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006150079
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1016/j.radonc.2011.05.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042497797
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1016/j.radonc.2017.01.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083544247
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1016/j.radonc.2017.01.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084104846
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1016/j.radonc.2017.03.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084104874
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1016/s1470-2045(16)30532-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003744409
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1080/02698590701498084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024621176
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1080/02841860600904821 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030251382
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1080/02841860600908954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004720951
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1093/jnci/djx015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083932849
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1097/00000658-199909000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060135098
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1097/00007611-199301000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082799417
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1097/jto.0b013e3182208e58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035497536
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1097/sla.0b013e31826b4dcc schema:sameAs https://app.dimensions.ai/details/publication/pub.1011154183
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1111/j.1541-0420.2009.01340.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052300072
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1136/gutjnl-2015-310912 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029185920
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1161/circoutcomes.115.001841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063343662
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1200/jco.1995.13.1.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082512517
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1200/jco.2008.19.6329 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017605315
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1200/jco.2008.19.6386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041129418
392 rdf:type schema:CreativeWork
393 https://doi.org/10.18637/jss.v045.i03 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068672674
394 rdf:type schema:CreativeWork
395 https://doi.org/10.18637/jss.v047.i04 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068672704
396 rdf:type schema:CreativeWork
397 https://doi.org/10.3978/j.issn.2072-1439.2013.12.03 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078889080
398 rdf:type schema:CreativeWork
399 https://www.grid.ac/institutes/grid.10253.35 schema:alternateName Philipp University of Marburg
400 schema:name Department of Radiation Oncology, University Hospital Jena, Jena, Germany
401 Department of Radiotherapy and Radiation Oncology, Philipps-University Marburg, University Hospital Giessen and Marburg, Marburg, Germany
402 rdf:type schema:Organization
403 https://www.grid.ac/institutes/grid.10423.34 schema:alternateName Hannover Medical School
404 schema:name Department of Radiotherapy and Special Oncology, Medical School Hannover, Hanover, Germany
405 rdf:type schema:Organization
406 https://www.grid.ac/institutes/grid.10493.3f schema:alternateName University of Rostock
407 schema:name Department of Radiation Oncology, University of Rostock, Rostock, Germany
408 rdf:type schema:Organization
409 https://www.grid.ac/institutes/grid.13648.38 schema:alternateName University Medical Center Hamburg-Eppendorf
410 schema:name Department of Radiation Oncology, University Hospital Hamburg, Hamburg, Germany
411 rdf:type schema:Organization
412 https://www.grid.ac/institutes/grid.16149.3b schema:alternateName University Hospital Münster
413 schema:name Department of Radiation Oncology, University Hospital Muenster, Muenster, Germany
414 rdf:type schema:Organization
415 https://www.grid.ac/institutes/grid.275559.9 schema:alternateName Jena University Hospital
416 schema:name Department of Radiation Oncology, University Hospital Jena, Jena, Germany
417 rdf:type schema:Organization
418 https://www.grid.ac/institutes/grid.410567.1 schema:alternateName University Hospital of Basel
419 schema:name Department of Radiation Oncology, University Hospital Basel, Basel, Switzerland
420 rdf:type schema:Organization
421 https://www.grid.ac/institutes/grid.411088.4 schema:alternateName University Hospital Frankfurt
422 schema:name Department of Radiation Oncology, University Hospital Frankfurt, Frankfurt, Germany
423 rdf:type schema:Organization
424 https://www.grid.ac/institutes/grid.411097.a schema:alternateName University Hospital Cologne
425 schema:name Department of Radiation Oncology, University Hospital of Cologne, Cologne, Germany
426 rdf:type schema:Organization
427 https://www.grid.ac/institutes/grid.411760.5 schema:alternateName University Hospital of Würzburg
428 schema:name Department of Radiation Oncology, University Hospital Wuerzburg, Wuerzburg, Germany
429 rdf:type schema:Organization
430 https://www.grid.ac/institutes/grid.411778.c schema:alternateName University Medical Centre Mannheim
431 schema:name Department of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany
432 rdf:type schema:Organization
433 https://www.grid.ac/institutes/grid.412301.5 schema:alternateName Universitätsklinikum Aachen
434 schema:name Department of Radiation Oncology, University Hospital Aachen, Aachen, Germany
435 rdf:type schema:Organization
436 https://www.grid.ac/institutes/grid.412353.2 schema:alternateName University Children’s Hospital Bern
437 schema:name Department of Radiation Oncology, University Hospital Bern, Bern, Switzerland
438 rdf:type schema:Organization
439 https://www.grid.ac/institutes/grid.4488.0 schema:alternateName TU Dresden
440 schema:name Department of Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
441 rdf:type schema:Organization
442 https://www.grid.ac/institutes/grid.461820.9 schema:alternateName University Hospital in Halle
443 schema:name Department of Radiation Oncology, University Hospital Halle, Halle, Germany
444 rdf:type schema:Organization
445 https://www.grid.ac/institutes/grid.488575.3 schema:alternateName Universitätsaugenklinik Magdeburg
446 schema:name Department of Radiation Oncology, University Hospital Magdeburg, Magdeburg, Germany
447 rdf:type schema:Organization
448 https://www.grid.ac/institutes/grid.491869.b schema:alternateName Helios Hospital Berlin-Buch
449 schema:name Department of Radiation Oncology, Helios Klinikum Berlin Buch, Berlin, Germany
450 rdf:type schema:Organization
451 https://www.grid.ac/institutes/grid.5252.0 schema:alternateName Ludwig Maximilian University of Munich
452 schema:name Department of Radiation Oncology, Ludwig Maximilians University Munich, Munich, Germany
453 rdf:type schema:Organization
454 https://www.grid.ac/institutes/grid.5253.1 schema:alternateName University Hospital Heidelberg
455 schema:name Department of Radiation Oncology, Klinikum rechts der Isar- Technische Universitaet Muenchen, Munich, Germany
456 Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany
457 rdf:type schema:Organization
458 https://www.grid.ac/institutes/grid.6936.a schema:alternateName Technical University Munich
459 schema:name Department of Radiation Oncology, Klinikum rechts der Isar- Technische Universitaet Muenchen, Munich, Germany
460 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...