Ontology type: schema:ScholarlyArticle Open Access: True
2016-07-04
AUTHORSChristophe Maritaz, Carole Metz, Nabil Baba-Hamed, Méryam Jardin-Szucs, Gaël Deplanque
ABSTRACTBACKGROUND: Cetuximab is a commonly used antibody agent in the treatment of colorectal or head and neck cancer. Although it is generally well tolerated in most patients, cetuximab has been associated with some rare but serious adverse events. Aseptic meningitis is one such distinctly uncommon adverse drug reaction. CASE PRESENTATION: We present the case of a middle-aged Caucasian patient, who presented with fever and headache within a few hours of starting cetuximab therapy and was diagnosed with cetuximab-induced aseptic meningitis after a complete workup. CONCLUSION: To our knowledge, this is the ninth case of cetuximab-induced aseptic meningitis reported in literature. Because of a nonspecific clinical presentation, this adverse drug reaction can be easily misdiagnosed. It is important to increase awareness of this potentially severe reaction among oncologists. More... »
PAGES384
http://scigraph.springernature.com/pub.10.1186/s12885-016-2434-7
DOIhttp://dx.doi.org/10.1186/s12885-016-2434-7
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1012929852
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/27378078
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Administration, Intravenous",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Anti-Bacterial Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Carcinoma, Squamous Cell",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cetuximab",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Head and Neck Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Meningitis, Aseptic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Treatment Outcome",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Pharmacy, Saint-Joseph Hospital, Paris, France",
"id": "http://www.grid.ac/institutes/grid.414363.7",
"name": [
"Department of Pharmacy, Saint-Joseph Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Maritaz",
"givenName": "Christophe",
"id": "sg:person.01126473305.27",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01126473305.27"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pharmacy, Saint-Joseph Hospital, Paris, France",
"id": "http://www.grid.ac/institutes/grid.414363.7",
"name": [
"Department of Pharmacy, Saint-Joseph Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Metz",
"givenName": "Carole",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Oncology, Saint-Joseph Hospital, Paris, France",
"id": "http://www.grid.ac/institutes/grid.414363.7",
"name": [
"Department of Oncology, Saint-Joseph Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Baba-Hamed",
"givenName": "Nabil",
"id": "sg:person.0624575614.78",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0624575614.78"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pharmacy, Saint-Joseph Hospital, Paris, France",
"id": "http://www.grid.ac/institutes/grid.414363.7",
"name": [
"Department of Pharmacy, Saint-Joseph Hospital, Paris, France"
],
"type": "Organization"
},
"familyName": "Jardin-Szucs",
"givenName": "M\u00e9ryam",
"id": "sg:person.015553016141.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015553016141.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Oncology, University hospital of Lausanne, Lausanne, Switzerland",
"id": "http://www.grid.ac/institutes/grid.8515.9",
"name": [
"Department of Oncology, University hospital of Lausanne, Lausanne, Switzerland"
],
"type": "Organization"
},
"familyName": "Deplanque",
"givenName": "Ga\u00ebl",
"id": "sg:person.01032513530.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01032513530.10"
],
"type": "Person"
}
],
"datePublished": "2016-07-04",
"datePublishedReg": "2016-07-04",
"description": "BACKGROUND: Cetuximab is a commonly used antibody agent in the treatment of colorectal or head and neck cancer. Although it is generally well tolerated in most patients, cetuximab has been associated with some rare but serious adverse events. Aseptic meningitis is one such distinctly uncommon adverse drug reaction.\nCASE PRESENTATION: We present the case of a middle-aged Caucasian patient, who presented with fever and headache within a few hours of starting cetuximab therapy and was diagnosed with cetuximab-induced aseptic meningitis after a complete workup.\nCONCLUSION: To our knowledge, this is the ninth case of cetuximab-induced aseptic meningitis reported in literature. Because of a nonspecific clinical presentation, this adverse drug reaction can be easily misdiagnosed. It is important to increase awareness of this potentially severe reaction among oncologists.",
"genre": "article",
"id": "sg:pub.10.1186/s12885-016-2434-7",
"inLanguage": "en",
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1024632",
"issn": [
"1471-2407"
],
"name": "BMC Cancer",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "16"
}
],
"keywords": [
"adverse drug reactions",
"aseptic meningitis",
"adverse events",
"drug reactions",
"uncommon adverse drug reaction",
"serious adverse events",
"nonspecific clinical presentation",
"treatment of colorectal",
"rare adverse events",
"cetuximab therapy",
"most patients",
"clinical presentation",
"antibody agents",
"complete workup",
"neck cancer",
"Caucasian patients",
"case report",
"ninth case",
"severe reactions",
"meningitis",
"cetuximab",
"patients",
"colorectal",
"headache",
"fever",
"oncologists",
"therapy",
"workup",
"cancer",
"treatment",
"cases",
"presentation",
"report",
"hours",
"events",
"review",
"agents",
"head",
"awareness",
"reaction",
"literature",
"knowledge",
"middle-aged Caucasian patient",
"cetuximab-induced aseptic meningitis"
],
"name": "Cetuximab-induced aseptic meningitis: case report and review of a rare adverse event",
"pagination": "384",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1012929852"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1186/s12885-016-2434-7"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"27378078"
]
}
],
"sameAs": [
"https://doi.org/10.1186/s12885-016-2434-7",
"https://app.dimensions.ai/details/publication/pub.1012929852"
],
"sdDataset": "articles",
"sdDatePublished": "2022-01-01T18:38",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_686.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1186/s12885-016-2434-7"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12885-016-2434-7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12885-016-2434-7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12885-016-2434-7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12885-016-2434-7'
This table displays all metadata directly associated to this object as RDF triples.
177 TRIPLES
21 PREDICATES
80 URIs
72 LITERALS
17 BLANK NODES