The Danish cancer pathway for patients with serious non-specific symptoms and signs of cancer–a cross-sectional study of patient characteristics and ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Mads Lind Ingeman, Morten Bondo Christensen, Flemming Bro, Søren T. Knudsen, Peter Vedsted

ABSTRACT

BACKGROUND: A Danish cancer pathway has been implemented for patients with serious non-specific symptoms and signs of cancer (NSSC-CPP). The initiative is one of several to improve the long diagnostic interval and the poor survival of Danish cancer patients. However, little is known about the patients investigated under this pathway. We aim to describe the characteristics of patients referred from general practice to the NSSC-CPP and to estimate the cancer probability and distribution in this population. METHODS: A cross-sectional study was performed, including all patients referred to the NSSC-CPP at the hospitals in Aarhus or Silkeborg in the Central Denmark Region between March 2012 and March 2013. Data were based on a questionnaire completed by the patient's general practitioner (GP) combined with nationwide registers. Cancer probability was the percentage of new cancers per investigated patient. Associations between patient characteristics and cancer diagnosis were estimated with prevalence rate ratios (PRRs) from a generalised linear model. RESULTS: The mean age of all 1278 included patients was 65.9 years, and 47.5 % were men. In total, 16.2 % of all patients had a cancer diagnosis after six months; the most common types were lung cancer (17.9 %), colorectal cancer (12.6 %), hematopoietic tissue cancer (10.1 %) and pancreatic cancer (9.2 %). All patients in combination had more than 80 different symptoms and 51 different clinical findings at referral. Most symptoms were non-specific and vague; weight loss and fatigue were present in more than half of all cases. The three most common clinical findings were 'affected general condition' (35.8 %), 'GP's gut feeling' (22.5 %) and 'findings from the abdomen' (13.0 %). A strong association was found between GP-estimated cancer risk at referral and probability of cancer. CONCLUSIONS: In total, 16.2 % of the patients referred through the NSSC-CPP had cancer. They constituted a heterogeneous group with many different symptoms and clinical findings. The GP's gut feeling was a common reason for referral which proved to be a strong predictor of cancer. The GP's overall estimation of the patient's risk of cancer at referral was associated with the probability of finding cancer. More... »

PAGES

421

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12885-015-1424-5

DOI

http://dx.doi.org/10.1186/s12885-015-1424-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039837797

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25990247


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross-Sectional Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Denmark", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Referral and Consultation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Surveys and Questionnaires", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Symptom Assessment", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Aarhus University", 
          "id": "https://www.grid.ac/institutes/grid.7048.b", 
          "name": [
            "Research Unit for General Practice, Aarhus University, Aarhus, Denmark", 
            "Research Centre for Cancer Diagnosis in Primary Care (CaP), Aarhus University, Aarhus, Denmark", 
            "Department of Public Health, Section for General Medical Practice, Aarhus University, Aarhus, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ingeman", 
        "givenName": "Mads Lind", 
        "id": "sg:person.0734641132.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734641132.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aarhus University", 
          "id": "https://www.grid.ac/institutes/grid.7048.b", 
          "name": [
            "Research Unit for General Practice, Aarhus University, Aarhus, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Christensen", 
        "givenName": "Morten Bondo", 
        "id": "sg:person.01031620207.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031620207.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aarhus University", 
          "id": "https://www.grid.ac/institutes/grid.7048.b", 
          "name": [
            "Research Unit for General Practice, Aarhus University, Aarhus, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bro", 
        "givenName": "Flemming", 
        "id": "sg:person.01162311550.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162311550.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aarhus University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.154185.c", 
          "name": [
            "Department of Endocrinology and Internal Medicine (MEA), Aarhus University Hospital, Noerrebrogade, Aarhus, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Knudsen", 
        "givenName": "S\u00f8ren T.", 
        "id": "sg:person.01243477410.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243477410.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aarhus University", 
          "id": "https://www.grid.ac/institutes/grid.7048.b", 
          "name": [
            "Research Unit for General Practice, Aarhus University, Aarhus, Denmark", 
            "Research Centre for Cancer Diagnosis in Primary Care (CaP), Aarhus University, Aarhus, Denmark"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vedsted", 
        "givenName": "Peter", 
        "id": "sg:person.01137025352.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137025352.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/bjc.2015.44", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000610955", 
          "https://doi.org/10.1038/bjc.2015.44"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.healthpol.2011.11.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002194464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1403494810387965", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002205599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1403494810387965", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002205599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(10)62231-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003353087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(94)90634-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004510159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(94)90634-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004510159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10654-011-9647-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008653899", 
          "https://doi.org/10.1007/s10654-011-9647-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/fampra/cmn028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009128603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2354.2005.00600.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009128902"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp11x606591", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009939478"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/13814781003653424", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010201156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.2012.68", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010902211", 
          "https://doi.org/10.1038/bjc.2012.68"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.2013.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013771450", 
          "https://doi.org/10.1038/bjc.2013.1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1472-6963-12-224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013894650", 
          "https://doi.org/10.1186/1472-6963-12-224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(13)70546-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015669631"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6605383", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017038554", 
          "https://doi.org/10.1038/sj.bjc.6605383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp11x572283", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018840374"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2013.01.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021438986"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp11x606807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022804992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1055-9965.epi-08-1118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023047648"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp14x680125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025373015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2407-14-636", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033292815", 
          "https://doi.org/10.1186/1471-2407-14-636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jclinepi.2011.12.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033393229"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/clep.s62855", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034524724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2296-15-75", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035763418", 
          "https://doi.org/10.1186/1471-2296-15-75"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6605396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037520129", 
          "https://doi.org/10.1038/sj.bjc.6605396"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6605396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037520129", 
          "https://doi.org/10.1038/sj.bjc.6605396"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1472-6963-11-284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037943739", 
          "https://doi.org/10.1186/1472-6963-11-284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp12x654551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044497140"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3122/jabfm.2012.02.110216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045842161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp09x420860", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046521375"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3399/bjgp12x658331", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047786070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.322.7302.1555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050392154"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.2013.791", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053263227", 
          "https://doi.org/10.1038/bjc.2013.791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1403494810393562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064001857"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1403494810393562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064001857"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1403494811399958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064001916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1403494811399958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064001916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077098699", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078246564", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078830449", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078851732", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083187895", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-12", 
    "datePublishedReg": "2015-12-01", 
    "description": "BACKGROUND: A Danish cancer pathway has been implemented for patients with serious non-specific symptoms and signs of cancer (NSSC-CPP). The initiative is one of several to improve the long diagnostic interval and the poor survival of Danish cancer patients. However, little is known about the patients investigated under this pathway. We aim to describe the characteristics of patients referred from general practice to the NSSC-CPP and to estimate the cancer probability and distribution in this population.\nMETHODS: A cross-sectional study was performed, including all patients referred to the NSSC-CPP at the hospitals in Aarhus or Silkeborg in the Central Denmark Region between March 2012 and March 2013. Data were based on a questionnaire completed by the patient's general practitioner (GP) combined with nationwide registers. Cancer probability was the percentage of new cancers per investigated patient. Associations between patient characteristics and cancer diagnosis were estimated with prevalence rate ratios (PRRs) from a generalised linear model.\nRESULTS: The mean age of all 1278 included patients was 65.9 years, and 47.5 % were men. In total, 16.2 % of all patients had a cancer diagnosis after six months; the most common types were lung cancer (17.9 %), colorectal cancer (12.6 %), hematopoietic tissue cancer (10.1 %) and pancreatic cancer (9.2 %). All patients in combination had more than 80 different symptoms and 51 different clinical findings at referral. Most symptoms were non-specific and vague; weight loss and fatigue were present in more than half of all cases. The three most common clinical findings were 'affected general condition' (35.8 %), 'GP's gut feeling' (22.5 %) and 'findings from the abdomen' (13.0 %). A strong association was found between GP-estimated cancer risk at referral and probability of cancer.\nCONCLUSIONS: In total, 16.2 % of the patients referred through the NSSC-CPP had cancer. They constituted a heterogeneous group with many different symptoms and clinical findings. The GP's gut feeling was a common reason for referral which proved to be a strong predictor of cancer. The GP's overall estimation of the patient's risk of cancer at referral was associated with the probability of finding cancer.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12885-015-1424-5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024632", 
        "issn": [
          "1471-2407"
        ], 
        "name": "BMC Cancer", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "The Danish cancer pathway for patients with serious non-specific symptoms and signs of cancer\u2013a cross-sectional study of patient characteristics and cancer probability", 
    "pagination": "421", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "bdc4c8e29c86e04cb44195161c8d472c7252d8acf2bd765c512815ec2c70d8b4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25990247"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100967800"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12885-015-1424-5"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039837797"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12885-015-1424-5", 
      "https://app.dimensions.ai/details/publication/pub.1039837797"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89807_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2Fs12885-015-1424-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12885-015-1424-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12885-015-1424-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12885-015-1424-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12885-015-1424-5'


 

This table displays all metadata directly associated to this object as RDF triples.

284 TRIPLES      21 PREDICATES      83 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12885-015-1424-5 schema:about N0161f9e2e4254f63bfabfe2e5d67373d
2 N147fbc8c5f824db9b31beafef82de79c
3 N48d0ff7088814bc9803d4aebe42aca56
4 N4e63e2da64bc4363bd22ef0fef60fe1b
5 N7ec0b966c88c4e01bb9088ea7248980c
6 N90dce2cbbf9248618e7f7fcac38c4d28
7 N9915b8d6532c4f4194d482bfe812bd5e
8 N9a8378b1fe9d4dc2b1241027dda630c6
9 N9b19b0ad689d49c9b24ce421b3274f60
10 N9edf763702c3459889342d3eb2e50922
11 Nc336c6b872494e8ab87b57fd3dd618b8
12 Nd57789846b4f4b5595da4c81405b1986
13 Nd6116d731113472292409b8b9a8853a8
14 Ne02bf151b17546b49256b087845f355e
15 Nfa9b785b084343a48e570171c7f5c59d
16 anzsrc-for:11
17 anzsrc-for:1117
18 schema:author N1fbb720f8c7e45d2b6c5b7d48fdd2617
19 schema:citation sg:pub.10.1007/s10654-011-9647-5
20 sg:pub.10.1038/bjc.2012.68
21 sg:pub.10.1038/bjc.2013.1
22 sg:pub.10.1038/bjc.2013.791
23 sg:pub.10.1038/bjc.2015.44
24 sg:pub.10.1038/sj.bjc.6605383
25 sg:pub.10.1038/sj.bjc.6605396
26 sg:pub.10.1186/1471-2296-15-75
27 sg:pub.10.1186/1471-2407-14-636
28 sg:pub.10.1186/1472-6963-11-284
29 sg:pub.10.1186/1472-6963-12-224
30 https://app.dimensions.ai/details/publication/pub.1077098699
31 https://app.dimensions.ai/details/publication/pub.1078246564
32 https://app.dimensions.ai/details/publication/pub.1078830449
33 https://app.dimensions.ai/details/publication/pub.1078851732
34 https://app.dimensions.ai/details/publication/pub.1083187895
35 https://doi.org/10.1016/j.ejca.2013.01.025
36 https://doi.org/10.1016/j.healthpol.2011.11.001
37 https://doi.org/10.1016/j.jclinepi.2011.12.006
38 https://doi.org/10.1016/s0140-6736(10)62231-3
39 https://doi.org/10.1016/s0140-6736(94)90634-3
40 https://doi.org/10.1016/s1470-2045(13)70546-1
41 https://doi.org/10.1093/fampra/cmn028
42 https://doi.org/10.1111/j.1365-2354.2005.00600.x
43 https://doi.org/10.1136/bmj.322.7302.1555
44 https://doi.org/10.1158/1055-9965.epi-08-1118
45 https://doi.org/10.1177/1403494810387965
46 https://doi.org/10.1177/1403494810393562
47 https://doi.org/10.1177/1403494811399958
48 https://doi.org/10.2147/clep.s62855
49 https://doi.org/10.3109/13814781003653424
50 https://doi.org/10.3122/jabfm.2012.02.110216
51 https://doi.org/10.3399/bjgp09x420860
52 https://doi.org/10.3399/bjgp11x572283
53 https://doi.org/10.3399/bjgp11x606591
54 https://doi.org/10.3399/bjgp11x606807
55 https://doi.org/10.3399/bjgp12x654551
56 https://doi.org/10.3399/bjgp12x658331
57 https://doi.org/10.3399/bjgp14x680125
58 schema:datePublished 2015-12
59 schema:datePublishedReg 2015-12-01
60 schema:description BACKGROUND: A Danish cancer pathway has been implemented for patients with serious non-specific symptoms and signs of cancer (NSSC-CPP). The initiative is one of several to improve the long diagnostic interval and the poor survival of Danish cancer patients. However, little is known about the patients investigated under this pathway. We aim to describe the characteristics of patients referred from general practice to the NSSC-CPP and to estimate the cancer probability and distribution in this population. METHODS: A cross-sectional study was performed, including all patients referred to the NSSC-CPP at the hospitals in Aarhus or Silkeborg in the Central Denmark Region between March 2012 and March 2013. Data were based on a questionnaire completed by the patient's general practitioner (GP) combined with nationwide registers. Cancer probability was the percentage of new cancers per investigated patient. Associations between patient characteristics and cancer diagnosis were estimated with prevalence rate ratios (PRRs) from a generalised linear model. RESULTS: The mean age of all 1278 included patients was 65.9 years, and 47.5 % were men. In total, 16.2 % of all patients had a cancer diagnosis after six months; the most common types were lung cancer (17.9 %), colorectal cancer (12.6 %), hematopoietic tissue cancer (10.1 %) and pancreatic cancer (9.2 %). All patients in combination had more than 80 different symptoms and 51 different clinical findings at referral. Most symptoms were non-specific and vague; weight loss and fatigue were present in more than half of all cases. The three most common clinical findings were 'affected general condition' (35.8 %), 'GP's gut feeling' (22.5 %) and 'findings from the abdomen' (13.0 %). A strong association was found between GP-estimated cancer risk at referral and probability of cancer. CONCLUSIONS: In total, 16.2 % of the patients referred through the NSSC-CPP had cancer. They constituted a heterogeneous group with many different symptoms and clinical findings. The GP's gut feeling was a common reason for referral which proved to be a strong predictor of cancer. The GP's overall estimation of the patient's risk of cancer at referral was associated with the probability of finding cancer.
61 schema:genre research_article
62 schema:inLanguage en
63 schema:isAccessibleForFree true
64 schema:isPartOf N1e5d7c0710c3413d9cabd1bc5090cc02
65 N685d8aa5dcad4fd5888b707ed2dd0144
66 sg:journal.1024632
67 schema:name The Danish cancer pathway for patients with serious non-specific symptoms and signs of cancer–a cross-sectional study of patient characteristics and cancer probability
68 schema:pagination 421
69 schema:productId N0d7ff615de3f4cc88fcf89ceb45283eb
70 N1482c94388144e0b8699db3fe5522c9e
71 N2f1ace5c80834615b736797fee68a99a
72 Nb88397cb581a4a2987f5f179176aaf4e
73 Nfbfc8bda5fe6469b8512dd175e969ce9
74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039837797
75 https://doi.org/10.1186/s12885-015-1424-5
76 schema:sdDatePublished 2019-04-11T09:57
77 schema:sdLicense https://scigraph.springernature.com/explorer/license/
78 schema:sdPublisher N96de8a29186245669edddcfed6d9a212
79 schema:url http://link.springer.com/10.1186%2Fs12885-015-1424-5
80 sgo:license sg:explorer/license/
81 sgo:sdDataset articles
82 rdf:type schema:ScholarlyArticle
83 N0161f9e2e4254f63bfabfe2e5d67373d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Symptom Assessment
85 rdf:type schema:DefinedTerm
86 N0d7ff615de3f4cc88fcf89ceb45283eb schema:name doi
87 schema:value 10.1186/s12885-015-1424-5
88 rdf:type schema:PropertyValue
89 N147fbc8c5f824db9b31beafef82de79c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Male
91 rdf:type schema:DefinedTerm
92 N1482c94388144e0b8699db3fe5522c9e schema:name readcube_id
93 schema:value bdc4c8e29c86e04cb44195161c8d472c7252d8acf2bd765c512815ec2c70d8b4
94 rdf:type schema:PropertyValue
95 N1e5d7c0710c3413d9cabd1bc5090cc02 schema:issueNumber 1
96 rdf:type schema:PublicationIssue
97 N1fbb720f8c7e45d2b6c5b7d48fdd2617 rdf:first sg:person.0734641132.55
98 rdf:rest N5078ae60ca1145c696ed4351b66793ba
99 N2f1ace5c80834615b736797fee68a99a schema:name dimensions_id
100 schema:value pub.1039837797
101 rdf:type schema:PropertyValue
102 N48d0ff7088814bc9803d4aebe42aca56 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Adolescent
104 rdf:type schema:DefinedTerm
105 N4e63e2da64bc4363bd22ef0fef60fe1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Referral and Consultation
107 rdf:type schema:DefinedTerm
108 N5078ae60ca1145c696ed4351b66793ba rdf:first sg:person.01031620207.38
109 rdf:rest Nfdd3916fcc97471d8ece03195af56fc3
110 N56387614e97944abbb5881e870ab8138 rdf:first sg:person.01137025352.99
111 rdf:rest rdf:nil
112 N685d8aa5dcad4fd5888b707ed2dd0144 schema:volumeNumber 15
113 rdf:type schema:PublicationVolume
114 N7ec0b966c88c4e01bb9088ea7248980c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Neoplasms
116 rdf:type schema:DefinedTerm
117 N90dce2cbbf9248618e7f7fcac38c4d28 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Surveys and Questionnaires
119 rdf:type schema:DefinedTerm
120 N96de8a29186245669edddcfed6d9a212 schema:name Springer Nature - SN SciGraph project
121 rdf:type schema:Organization
122 N9915b8d6532c4f4194d482bfe812bd5e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Adult
124 rdf:type schema:DefinedTerm
125 N9a8378b1fe9d4dc2b1241027dda630c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Young Adult
127 rdf:type schema:DefinedTerm
128 N9b19b0ad689d49c9b24ce421b3274f60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Humans
130 rdf:type schema:DefinedTerm
131 N9edf763702c3459889342d3eb2e50922 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Aged, 80 and over
133 rdf:type schema:DefinedTerm
134 Nb88397cb581a4a2987f5f179176aaf4e schema:name nlm_unique_id
135 schema:value 100967800
136 rdf:type schema:PropertyValue
137 Nc336c6b872494e8ab87b57fd3dd618b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Cross-Sectional Studies
139 rdf:type schema:DefinedTerm
140 Nd57789846b4f4b5595da4c81405b1986 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Middle Aged
142 rdf:type schema:DefinedTerm
143 Nd6116d731113472292409b8b9a8853a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Denmark
145 rdf:type schema:DefinedTerm
146 Ne02bf151b17546b49256b087845f355e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Female
148 rdf:type schema:DefinedTerm
149 Neca0c9a050234a99a556c42422c905ac rdf:first sg:person.01243477410.21
150 rdf:rest N56387614e97944abbb5881e870ab8138
151 Nfa9b785b084343a48e570171c7f5c59d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Aged
153 rdf:type schema:DefinedTerm
154 Nfbfc8bda5fe6469b8512dd175e969ce9 schema:name pubmed_id
155 schema:value 25990247
156 rdf:type schema:PropertyValue
157 Nfdd3916fcc97471d8ece03195af56fc3 rdf:first sg:person.01162311550.95
158 rdf:rest Neca0c9a050234a99a556c42422c905ac
159 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
160 schema:name Medical and Health Sciences
161 rdf:type schema:DefinedTerm
162 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
163 schema:name Public Health and Health Services
164 rdf:type schema:DefinedTerm
165 sg:journal.1024632 schema:issn 1471-2407
166 schema:name BMC Cancer
167 rdf:type schema:Periodical
168 sg:person.01031620207.38 schema:affiliation https://www.grid.ac/institutes/grid.7048.b
169 schema:familyName Christensen
170 schema:givenName Morten Bondo
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031620207.38
172 rdf:type schema:Person
173 sg:person.01137025352.99 schema:affiliation https://www.grid.ac/institutes/grid.7048.b
174 schema:familyName Vedsted
175 schema:givenName Peter
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137025352.99
177 rdf:type schema:Person
178 sg:person.01162311550.95 schema:affiliation https://www.grid.ac/institutes/grid.7048.b
179 schema:familyName Bro
180 schema:givenName Flemming
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162311550.95
182 rdf:type schema:Person
183 sg:person.01243477410.21 schema:affiliation https://www.grid.ac/institutes/grid.154185.c
184 schema:familyName Knudsen
185 schema:givenName Søren T.
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01243477410.21
187 rdf:type schema:Person
188 sg:person.0734641132.55 schema:affiliation https://www.grid.ac/institutes/grid.7048.b
189 schema:familyName Ingeman
190 schema:givenName Mads Lind
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734641132.55
192 rdf:type schema:Person
193 sg:pub.10.1007/s10654-011-9647-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008653899
194 https://doi.org/10.1007/s10654-011-9647-5
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/bjc.2012.68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010902211
197 https://doi.org/10.1038/bjc.2012.68
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/bjc.2013.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013771450
200 https://doi.org/10.1038/bjc.2013.1
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/bjc.2013.791 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053263227
203 https://doi.org/10.1038/bjc.2013.791
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/bjc.2015.44 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000610955
206 https://doi.org/10.1038/bjc.2015.44
207 rdf:type schema:CreativeWork
208 sg:pub.10.1038/sj.bjc.6605383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017038554
209 https://doi.org/10.1038/sj.bjc.6605383
210 rdf:type schema:CreativeWork
211 sg:pub.10.1038/sj.bjc.6605396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037520129
212 https://doi.org/10.1038/sj.bjc.6605396
213 rdf:type schema:CreativeWork
214 sg:pub.10.1186/1471-2296-15-75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035763418
215 https://doi.org/10.1186/1471-2296-15-75
216 rdf:type schema:CreativeWork
217 sg:pub.10.1186/1471-2407-14-636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033292815
218 https://doi.org/10.1186/1471-2407-14-636
219 rdf:type schema:CreativeWork
220 sg:pub.10.1186/1472-6963-11-284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037943739
221 https://doi.org/10.1186/1472-6963-11-284
222 rdf:type schema:CreativeWork
223 sg:pub.10.1186/1472-6963-12-224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013894650
224 https://doi.org/10.1186/1472-6963-12-224
225 rdf:type schema:CreativeWork
226 https://app.dimensions.ai/details/publication/pub.1077098699 schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1078246564 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1078830449 schema:CreativeWork
229 https://app.dimensions.ai/details/publication/pub.1078851732 schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1083187895 schema:CreativeWork
231 https://doi.org/10.1016/j.ejca.2013.01.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021438986
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/j.healthpol.2011.11.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002194464
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/j.jclinepi.2011.12.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033393229
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/s0140-6736(10)62231-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003353087
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/s0140-6736(94)90634-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004510159
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/s1470-2045(13)70546-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015669631
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1093/fampra/cmn028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009128603
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1111/j.1365-2354.2005.00600.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009128902
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1136/bmj.322.7302.1555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050392154
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1158/1055-9965.epi-08-1118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023047648
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1177/1403494810387965 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002205599
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1177/1403494810393562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064001857
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1177/1403494811399958 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064001916
256 rdf:type schema:CreativeWork
257 https://doi.org/10.2147/clep.s62855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034524724
258 rdf:type schema:CreativeWork
259 https://doi.org/10.3109/13814781003653424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010201156
260 rdf:type schema:CreativeWork
261 https://doi.org/10.3122/jabfm.2012.02.110216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045842161
262 rdf:type schema:CreativeWork
263 https://doi.org/10.3399/bjgp09x420860 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046521375
264 rdf:type schema:CreativeWork
265 https://doi.org/10.3399/bjgp11x572283 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018840374
266 rdf:type schema:CreativeWork
267 https://doi.org/10.3399/bjgp11x606591 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009939478
268 rdf:type schema:CreativeWork
269 https://doi.org/10.3399/bjgp11x606807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022804992
270 rdf:type schema:CreativeWork
271 https://doi.org/10.3399/bjgp12x654551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044497140
272 rdf:type schema:CreativeWork
273 https://doi.org/10.3399/bjgp12x658331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047786070
274 rdf:type schema:CreativeWork
275 https://doi.org/10.3399/bjgp14x680125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025373015
276 rdf:type schema:CreativeWork
277 https://www.grid.ac/institutes/grid.154185.c schema:alternateName Aarhus University Hospital
278 schema:name Department of Endocrinology and Internal Medicine (MEA), Aarhus University Hospital, Noerrebrogade, Aarhus, Denmark
279 rdf:type schema:Organization
280 https://www.grid.ac/institutes/grid.7048.b schema:alternateName Aarhus University
281 schema:name Department of Public Health, Section for General Medical Practice, Aarhus University, Aarhus, Denmark
282 Research Centre for Cancer Diagnosis in Primary Care (CaP), Aarhus University, Aarhus, Denmark
283 Research Unit for General Practice, Aarhus University, Aarhus, Denmark
284 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...