Physical activity and metabolic health in chronic kidney disease: a cross-sectional study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12

AUTHORS

Wilson Bowlby, Leila R. Zelnick, Connor Henry, Jonathan Himmelfarb, Steven E. Kahn, Bryan Kestenbaum, Cassianne Robinson-Cohen, Kristina M. Utzschneider, Ian H. de Boer

ABSTRACT

BACKGROUND: Patients with chronic kidney disease (CKD) are at high risk of progression to end stage renal disease and cardiovascular events. Physical activity may reduce these risks by improving metabolic health. We tested associations of physical activity with central components of metabolic health among people with moderate-severe non-diabetic CKD. METHODS: We performed a cross-sectional study of 47 people with CKD (estimated GFR <60 ml/min/1.73 m2) and 29 healthy control subjects. Accelerometry was used to measured physical activity over 7 days, the hyperinsulinemic-euglycemic clamp was used to measure insulin sensitivity, and DXA was used to measured fat mass. We tested associations of physical activity with insulin sensitivity, fat mass, blood pressure, serum lipid concentrations, and serum high sensitivity C-reactive protein concentration using multivariable linear regression, adjusting for possible confounding factors. RESULTS: Participants with CKD were less active than participants without CKD (mean (SD) 468.1 (233.1) versus 662.3 (292.5) counts per minute) and had lower insulin sensitivity (4.1 (2.1) versus 5.2 (2.0 (mg/min)/(μU/mL)), higher fat mass (32.0 (11.4) versus 29.4 (14.8) kg), and higher triglyceride concentrations (153.2 (91.6) versus 99.6 (66.8) mg/dL). With adjustment for demographics, comorbidity, medications, and estimated GFR, each two-fold higher level of physical activity was associated with a 0.9 (mg/min)/(μU/mL) higher insulin sensitivity (95% CI 0.2, 1.5, p = 0.006), an 8.0 kg lower fat mass (-12.9, -3.1, p = 0.001), and a 37.9 mg/dL lower triglyceride concentration (-71.9, -3.9, p = 0.03). Associations of physical activity with insulin sensitivity and triglycerides did not differ significantly by CKD status (p-values for interaction >0.3). CONCLUSIONS: Greater physical activity is associated with multiple manifestations of metabolic health among people with moderate-severe CKD. More... »

PAGES

187

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12882-016-0400-x

DOI

http://dx.doi.org/10.1186/s12882-016-0400-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008889577

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27876008


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Absorptiometry, Photon", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Accelerometry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adipose Tissue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Pressure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "C-Reactive Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholesterol, HDL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross-Sectional Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exercise", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glomerular Filtration Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Homeostasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Insulin Resistance", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renal Insufficiency, Chronic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Triglycerides", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "University of Washington School of Medicine, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bowlby", 
        "givenName": "Wilson", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zelnick", 
        "givenName": "Leila R.", 
        "id": "sg:person.01157116346.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157116346.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Henry", 
        "givenName": "Connor", 
        "id": "sg:person.016250721211.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016250721211.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Himmelfarb", 
        "givenName": "Jonathan", 
        "id": "sg:person.01040512430.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040512430.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "VA Puget Sound Health Care System, Seattle, WA, USA", 
            "Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kahn", 
        "givenName": "Steven E.", 
        "id": "sg:person.01027463620.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027463620.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kestenbaum", 
        "givenName": "Bryan", 
        "id": "sg:person.011642263477.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011642263477.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Robinson-Cohen", 
        "givenName": "Cassianne", 
        "id": "sg:person.013165261347.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013165261347.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Washington", 
          "id": "https://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "VA Puget Sound Health Care System, Seattle, WA, USA", 
            "Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Utzschneider", 
        "givenName": "Kristina M.", 
        "id": "sg:person.01221417652.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221417652.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "VA Puget Sound Health Care System", 
          "id": "https://www.grid.ac/institutes/grid.413919.7", 
          "name": [
            "Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA", 
            "VA Puget Sound Health Care System, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Boer", 
        "givenName": "Ian H.", 
        "id": "sg:person.0600614462.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600614462.48"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.pcad.2013.10.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000880714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2014.09.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002138676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.01970309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004109474"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2005010106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006585555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2005010106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006585555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2005010106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006585555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2013040392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007151512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2013040392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007151512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00132577-200512000-00018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008027304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00132577-200512000-00018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008027304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/h07-059", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009240573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.jrn.2012.04.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009252291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diabres.2012.09.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012133833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4065/mcp.2010.0336", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015539077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2011.10.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015590754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/01.mss.0000185674.09066.8a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018848012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/01.mss.0000185674.09066.8a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018848012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/01.mss.0000185674.09066.8a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018848012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1464-5491.2002.00719.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022497922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000042700.48769.59", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023140779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1114248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024595909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1046/j.1523-1755.1998.00898.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025081579", 
          "https://doi.org/10.1046/j.1523-1755.1998.00898.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.09810913", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025752558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci110067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027367194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00280883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027902786", 
          "https://doi.org/10.1007/bf00280883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00280883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027902786", 
          "https://doi.org/10.1007/bf00280883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00280883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027902786", 
          "https://doi.org/10.1007/bf00280883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2012070702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028152013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2012070702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028152013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.05230513", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028342587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(10)60674-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033235001"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/mss.0b013e31820c0130", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033545909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1249/mss.0b013e31820c0130", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033545909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.ajkd.2006.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034880427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.11861111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036048321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2006030204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036483774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2006030204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036483774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnh.0b013e32834b23c1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042351993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mnh.0b013e32834b23c1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042351993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.54.11.3252", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046542721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2012/806102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047856911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000130659", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047926312"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1464-5491.2003.00869.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051872071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.08410814", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053082662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2215/cjn.04071206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053528324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269215506069475", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053961529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0269215506069475", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053961529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2015070756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068243570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2015070756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068243570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1681/asn.2015070756", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068243570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5527/wjn.v3.i4.210", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072935333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpendo.1979.237.3.e214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079974987"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12", 
    "datePublishedReg": "2016-12-01", 
    "description": "BACKGROUND: Patients with chronic kidney disease (CKD) are at high risk of progression to end stage renal disease and cardiovascular events. Physical activity may reduce these risks by improving metabolic health. We tested associations of physical activity with central components of metabolic health among people with moderate-severe non-diabetic CKD.\nMETHODS: We performed a cross-sectional study of 47 people with CKD (estimated GFR <60\u00a0ml/min/1.73\u00a0m2) and 29 healthy control subjects. Accelerometry was used to measured physical activity over 7\u00a0days, the hyperinsulinemic-euglycemic clamp was used to measure insulin sensitivity, and DXA was used to measured fat mass. We tested associations of physical activity with insulin sensitivity, fat mass, blood pressure, serum lipid concentrations, and serum high sensitivity C-reactive protein concentration using multivariable linear regression, adjusting for possible confounding factors.\nRESULTS: Participants with CKD were less active than participants without CKD (mean (SD) 468.1 (233.1) versus 662.3 (292.5) counts per minute) and had lower insulin sensitivity (4.1 (2.1) versus 5.2 (2.0 (mg/min)/(\u03bcU/mL)), higher fat mass (32.0 (11.4) versus 29.4 (14.8) kg), and higher triglyceride concentrations (153.2 (91.6) versus 99.6 (66.8) mg/dL). With adjustment for demographics, comorbidity, medications, and estimated GFR, each two-fold higher level of physical activity was associated with a 0.9 (mg/min)/(\u03bcU/mL) higher insulin sensitivity (95% CI 0.2, 1.5, p\u2009=\u20090.006), an 8.0\u00a0kg lower fat mass (-12.9, -3.1, p\u2009=\u20090.001), and a 37.9\u00a0mg/dL lower triglyceride concentration (-71.9, -3.9, p\u2009=\u20090.03). Associations of physical activity with insulin sensitivity and triglycerides did not differ significantly by CKD status (p-values for interaction >0.3).\nCONCLUSIONS: Greater physical activity is associated with multiple manifestations of metabolic health among people with moderate-severe CKD.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12882-016-0400-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2438992", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2500073", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2500161", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2686693", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.3535745", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2438966", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6810398", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1024626", 
        "issn": [
          "1471-2369"
        ], 
        "name": "BMC Nephrology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "17"
      }
    ], 
    "name": "Physical activity and metabolic health in chronic kidney disease: a cross-sectional study", 
    "pagination": "187", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "2a5a4bedd8b6f0b495fee590e6ae12610cd33cd377e401d5d0259dbfdaafbe84"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27876008"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100967793"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12882-016-0400-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1008889577"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12882-016-0400-x", 
      "https://app.dimensions.ai/details/publication/pub.1008889577"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:21", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87079_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1186%2Fs12882-016-0400-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12882-016-0400-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12882-016-0400-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12882-016-0400-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12882-016-0400-x'


 

This table displays all metadata directly associated to this object as RDF triples.

337 TRIPLES      21 PREDICATES      86 URIs      41 LITERALS      29 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12882-016-0400-x schema:about N04ff697bb2ab4acfa1d9dc1335258d80
2 N08f0d737b99f4dc1a268705e9c2cf618
3 N16fd32e54554475d8940111a15e0f0dd
4 N207d4d865bf647b09f670cef3c747910
5 N2310c8dc2e9b4f91b7f66612307e24f2
6 N3965c071b378455bbe80f0e978463e96
7 N49582c1e922643548d142a675d8277dd
8 N53f31c0107bc446f96316c99515b8aea
9 N5a7bd02927064a809fb2c7c47f434584
10 N73705979984c4b2c884c108ab0be2ec2
11 N91a69e70ccc64d98bfdd7762ef859a86
12 N9e2379d1bc9248e3bb950e14f48088ea
13 N9e360d6d5118479e92ac105f65d8daef
14 Nb6bbf6ab81e24dde86a1fac97ca4f9bc
15 Nbaf7043a553047cb90985d9704ce0a43
16 Nbb7dbf8d0a1c4dfd95ca784bcdfd6501
17 Nbebfa3230044496085710eadb8981382
18 Nc209c0f2a4af4046904828ba2cf8268a
19 Nc7c6637783b24e96b7408196a8e3faeb
20 Nfcd4703a17b14f5a9de1b0ecee396501
21 anzsrc-for:11
22 anzsrc-for:1103
23 schema:author Neb4905ac540d4e31b0adc96d12276f33
24 schema:citation sg:pub.10.1007/bf00280883
25 sg:pub.10.1046/j.1523-1755.1998.00898.x
26 https://doi.org/10.1016/j.diabres.2012.09.009
27 https://doi.org/10.1016/j.pcad.2013.10.005
28 https://doi.org/10.1016/s0140-6736(10)60674-5
29 https://doi.org/10.1046/j.1464-5491.2002.00719.x
30 https://doi.org/10.1046/j.1464-5491.2003.00869.x
31 https://doi.org/10.1053/j.ajkd.2006.08.008
32 https://doi.org/10.1053/j.ajkd.2011.10.008
33 https://doi.org/10.1053/j.ajkd.2014.09.016
34 https://doi.org/10.1053/j.jrn.2012.04.008
35 https://doi.org/10.1056/nejmoa1114248
36 https://doi.org/10.1097/00132577-200512000-00018
37 https://doi.org/10.1097/mnh.0b013e32834b23c1
38 https://doi.org/10.1139/h07-059
39 https://doi.org/10.1152/ajpendo.1979.237.3.e214
40 https://doi.org/10.1155/2012/806102
41 https://doi.org/10.1159/000130659
42 https://doi.org/10.1161/01.cir.0000042700.48769.59
43 https://doi.org/10.1172/jci110067
44 https://doi.org/10.1177/0269215506069475
45 https://doi.org/10.1249/01.mss.0000185674.09066.8a
46 https://doi.org/10.1249/mss.0b013e31820c0130
47 https://doi.org/10.1681/asn.2005010106
48 https://doi.org/10.1681/asn.2006030204
49 https://doi.org/10.1681/asn.2012070702
50 https://doi.org/10.1681/asn.2013040392
51 https://doi.org/10.1681/asn.2015070756
52 https://doi.org/10.2215/cjn.01970309
53 https://doi.org/10.2215/cjn.04071206
54 https://doi.org/10.2215/cjn.05230513
55 https://doi.org/10.2215/cjn.08410814
56 https://doi.org/10.2215/cjn.09810913
57 https://doi.org/10.2215/cjn.11861111
58 https://doi.org/10.2337/diabetes.54.11.3252
59 https://doi.org/10.4065/mcp.2010.0336
60 https://doi.org/10.5527/wjn.v3.i4.210
61 schema:datePublished 2016-12
62 schema:datePublishedReg 2016-12-01
63 schema:description BACKGROUND: Patients with chronic kidney disease (CKD) are at high risk of progression to end stage renal disease and cardiovascular events. Physical activity may reduce these risks by improving metabolic health. We tested associations of physical activity with central components of metabolic health among people with moderate-severe non-diabetic CKD. METHODS: We performed a cross-sectional study of 47 people with CKD (estimated GFR <60 ml/min/1.73 m2) and 29 healthy control subjects. Accelerometry was used to measured physical activity over 7 days, the hyperinsulinemic-euglycemic clamp was used to measure insulin sensitivity, and DXA was used to measured fat mass. We tested associations of physical activity with insulin sensitivity, fat mass, blood pressure, serum lipid concentrations, and serum high sensitivity C-reactive protein concentration using multivariable linear regression, adjusting for possible confounding factors. RESULTS: Participants with CKD were less active than participants without CKD (mean (SD) 468.1 (233.1) versus 662.3 (292.5) counts per minute) and had lower insulin sensitivity (4.1 (2.1) versus 5.2 (2.0 (mg/min)/(μU/mL)), higher fat mass (32.0 (11.4) versus 29.4 (14.8) kg), and higher triglyceride concentrations (153.2 (91.6) versus 99.6 (66.8) mg/dL). With adjustment for demographics, comorbidity, medications, and estimated GFR, each two-fold higher level of physical activity was associated with a 0.9 (mg/min)/(μU/mL) higher insulin sensitivity (95% CI 0.2, 1.5, p = 0.006), an 8.0 kg lower fat mass (-12.9, -3.1, p = 0.001), and a 37.9 mg/dL lower triglyceride concentration (-71.9, -3.9, p = 0.03). Associations of physical activity with insulin sensitivity and triglycerides did not differ significantly by CKD status (p-values for interaction >0.3). CONCLUSIONS: Greater physical activity is associated with multiple manifestations of metabolic health among people with moderate-severe CKD.
64 schema:genre research_article
65 schema:inLanguage en
66 schema:isAccessibleForFree true
67 schema:isPartOf N2a4aa8c0e9a74404a1cb223aed760655
68 Na064445ba92a4a2299d6d47ef127f78f
69 sg:journal.1024626
70 schema:name Physical activity and metabolic health in chronic kidney disease: a cross-sectional study
71 schema:pagination 187
72 schema:productId N0bdce5c8e6ac4a80bd77bdd0ce87b481
73 N419a387bcb4f4c0ba969f1ac351598ae
74 Na5b6346f71944006b81cc23f895168b4
75 Nadcdda4ec1164d038fa85323d84e3149
76 Nb8b554846ee249ee8b1fb9ce169300e7
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008889577
78 https://doi.org/10.1186/s12882-016-0400-x
79 schema:sdDatePublished 2019-04-11T12:21
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher Nb18c07686b2f4c49a483734bbf7e6320
82 schema:url https://link.springer.com/10.1186%2Fs12882-016-0400-x
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N04ff697bb2ab4acfa1d9dc1335258d80 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Blood Pressure
88 rdf:type schema:DefinedTerm
89 N08f0d737b99f4dc1a268705e9c2cf618 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Male
91 rdf:type schema:DefinedTerm
92 N0bdce5c8e6ac4a80bd77bdd0ce87b481 schema:name readcube_id
93 schema:value 2a5a4bedd8b6f0b495fee590e6ae12610cd33cd377e401d5d0259dbfdaafbe84
94 rdf:type schema:PropertyValue
95 N16fd32e54554475d8940111a15e0f0dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Triglycerides
97 rdf:type schema:DefinedTerm
98 N207d4d865bf647b09f670cef3c747910 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name C-Reactive Protein
100 rdf:type schema:DefinedTerm
101 N2310c8dc2e9b4f91b7f66612307e24f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Cross-Sectional Studies
103 rdf:type schema:DefinedTerm
104 N2a4aa8c0e9a74404a1cb223aed760655 schema:volumeNumber 17
105 rdf:type schema:PublicationVolume
106 N2da45f9ac335464ba17599bc375e9ecc rdf:first sg:person.011642263477.11
107 rdf:rest Nc3fb68656b8f4d42a727ff79bd8ae77c
108 N3965c071b378455bbe80f0e978463e96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Absorptiometry, Photon
110 rdf:type schema:DefinedTerm
111 N419a387bcb4f4c0ba969f1ac351598ae schema:name doi
112 schema:value 10.1186/s12882-016-0400-x
113 rdf:type schema:PropertyValue
114 N49582c1e922643548d142a675d8277dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Humans
116 rdf:type schema:DefinedTerm
117 N4f32ae8d6ba84ba8aac6069d16138e11 rdf:first sg:person.0600614462.48
118 rdf:rest rdf:nil
119 N539f9b4cef3e43f4b40be8209201e38e rdf:first sg:person.01027463620.91
120 rdf:rest N2da45f9ac335464ba17599bc375e9ecc
121 N53f31c0107bc446f96316c99515b8aea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Aged, 80 and over
123 rdf:type schema:DefinedTerm
124 N5a7bd02927064a809fb2c7c47f434584 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Female
126 rdf:type schema:DefinedTerm
127 N654043103ea14ec6a11463bdb3e408a5 rdf:first sg:person.016250721211.77
128 rdf:rest Nbb7041111dc647e5af6f9b038ca75b2a
129 N73705979984c4b2c884c108ab0be2ec2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Insulin Resistance
131 rdf:type schema:DefinedTerm
132 N8feb708d571d416ab1e53299e5bad7b2 rdf:first sg:person.01157116346.52
133 rdf:rest N654043103ea14ec6a11463bdb3e408a5
134 N91a69e70ccc64d98bfdd7762ef859a86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Middle Aged
136 rdf:type schema:DefinedTerm
137 N9e2379d1bc9248e3bb950e14f48088ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Case-Control Studies
139 rdf:type schema:DefinedTerm
140 N9e360d6d5118479e92ac105f65d8daef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Homeostasis
142 rdf:type schema:DefinedTerm
143 Na064445ba92a4a2299d6d47ef127f78f schema:issueNumber 1
144 rdf:type schema:PublicationIssue
145 Na5b6346f71944006b81cc23f895168b4 schema:name dimensions_id
146 schema:value pub.1008889577
147 rdf:type schema:PropertyValue
148 Nadcdda4ec1164d038fa85323d84e3149 schema:name nlm_unique_id
149 schema:value 100967793
150 rdf:type schema:PropertyValue
151 Nb18c07686b2f4c49a483734bbf7e6320 schema:name Springer Nature - SN SciGraph project
152 rdf:type schema:Organization
153 Nb6bbf6ab81e24dde86a1fac97ca4f9bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Adipose Tissue
155 rdf:type schema:DefinedTerm
156 Nb8b554846ee249ee8b1fb9ce169300e7 schema:name pubmed_id
157 schema:value 27876008
158 rdf:type schema:PropertyValue
159 Nbaf7043a553047cb90985d9704ce0a43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Cholesterol, HDL
161 rdf:type schema:DefinedTerm
162 Nbb7041111dc647e5af6f9b038ca75b2a rdf:first sg:person.01040512430.89
163 rdf:rest N539f9b4cef3e43f4b40be8209201e38e
164 Nbb7dbf8d0a1c4dfd95ca784bcdfd6501 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Glomerular Filtration Rate
166 rdf:type schema:DefinedTerm
167 Nbebfa3230044496085710eadb8981382 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Aged
169 rdf:type schema:DefinedTerm
170 Nc209c0f2a4af4046904828ba2cf8268a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Renal Insufficiency, Chronic
172 rdf:type schema:DefinedTerm
173 Nc3fb68656b8f4d42a727ff79bd8ae77c rdf:first sg:person.013165261347.40
174 rdf:rest Nd351d664ebdf42fe96f59771ba68e09d
175 Nc63ef98420c54a618f5e33f0a40f4e3d schema:affiliation https://www.grid.ac/institutes/grid.34477.33
176 schema:familyName Bowlby
177 schema:givenName Wilson
178 rdf:type schema:Person
179 Nc7c6637783b24e96b7408196a8e3faeb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Accelerometry
181 rdf:type schema:DefinedTerm
182 Nd351d664ebdf42fe96f59771ba68e09d rdf:first sg:person.01221417652.86
183 rdf:rest N4f32ae8d6ba84ba8aac6069d16138e11
184 Neb4905ac540d4e31b0adc96d12276f33 rdf:first Nc63ef98420c54a618f5e33f0a40f4e3d
185 rdf:rest N8feb708d571d416ab1e53299e5bad7b2
186 Nfcd4703a17b14f5a9de1b0ecee396501 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Exercise
188 rdf:type schema:DefinedTerm
189 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
190 schema:name Medical and Health Sciences
191 rdf:type schema:DefinedTerm
192 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
193 schema:name Clinical Sciences
194 rdf:type schema:DefinedTerm
195 sg:grant.2438966 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
196 rdf:type schema:MonetaryGrant
197 sg:grant.2438992 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
198 rdf:type schema:MonetaryGrant
199 sg:grant.2500073 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
200 rdf:type schema:MonetaryGrant
201 sg:grant.2500161 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
202 rdf:type schema:MonetaryGrant
203 sg:grant.2686693 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
204 rdf:type schema:MonetaryGrant
205 sg:grant.3535745 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
206 rdf:type schema:MonetaryGrant
207 sg:grant.6810398 http://pending.schema.org/fundedItem sg:pub.10.1186/s12882-016-0400-x
208 rdf:type schema:MonetaryGrant
209 sg:journal.1024626 schema:issn 1471-2369
210 schema:name BMC Nephrology
211 rdf:type schema:Periodical
212 sg:person.01027463620.91 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
213 schema:familyName Kahn
214 schema:givenName Steven E.
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027463620.91
216 rdf:type schema:Person
217 sg:person.01040512430.89 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
218 schema:familyName Himmelfarb
219 schema:givenName Jonathan
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040512430.89
221 rdf:type schema:Person
222 sg:person.01157116346.52 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
223 schema:familyName Zelnick
224 schema:givenName Leila R.
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157116346.52
226 rdf:type schema:Person
227 sg:person.011642263477.11 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
228 schema:familyName Kestenbaum
229 schema:givenName Bryan
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011642263477.11
231 rdf:type schema:Person
232 sg:person.01221417652.86 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
233 schema:familyName Utzschneider
234 schema:givenName Kristina M.
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221417652.86
236 rdf:type schema:Person
237 sg:person.013165261347.40 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
238 schema:familyName Robinson-Cohen
239 schema:givenName Cassianne
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013165261347.40
241 rdf:type schema:Person
242 sg:person.016250721211.77 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
243 schema:familyName Henry
244 schema:givenName Connor
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016250721211.77
246 rdf:type schema:Person
247 sg:person.0600614462.48 schema:affiliation https://www.grid.ac/institutes/grid.413919.7
248 schema:familyName de Boer
249 schema:givenName Ian H.
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600614462.48
251 rdf:type schema:Person
252 sg:pub.10.1007/bf00280883 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027902786
253 https://doi.org/10.1007/bf00280883
254 rdf:type schema:CreativeWork
255 sg:pub.10.1046/j.1523-1755.1998.00898.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025081579
256 https://doi.org/10.1046/j.1523-1755.1998.00898.x
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1016/j.diabres.2012.09.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012133833
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1016/j.pcad.2013.10.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000880714
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1016/s0140-6736(10)60674-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033235001
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1046/j.1464-5491.2002.00719.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022497922
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1046/j.1464-5491.2003.00869.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051872071
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1053/j.ajkd.2006.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034880427
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1053/j.ajkd.2011.10.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015590754
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1053/j.ajkd.2014.09.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002138676
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1053/j.jrn.2012.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009252291
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1056/nejmoa1114248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024595909
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1097/00132577-200512000-00018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008027304
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1097/mnh.0b013e32834b23c1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042351993
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1139/h07-059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009240573
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1152/ajpendo.1979.237.3.e214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079974987
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1155/2012/806102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047856911
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1159/000130659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047926312
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1161/01.cir.0000042700.48769.59 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023140779
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1172/jci110067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027367194
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1177/0269215506069475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053961529
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1249/01.mss.0000185674.09066.8a schema:sameAs https://app.dimensions.ai/details/publication/pub.1018848012
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1249/mss.0b013e31820c0130 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033545909
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1681/asn.2005010106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006585555
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1681/asn.2006030204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036483774
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1681/asn.2012070702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028152013
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1681/asn.2013040392 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007151512
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1681/asn.2015070756 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068243570
309 rdf:type schema:CreativeWork
310 https://doi.org/10.2215/cjn.01970309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004109474
311 rdf:type schema:CreativeWork
312 https://doi.org/10.2215/cjn.04071206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053528324
313 rdf:type schema:CreativeWork
314 https://doi.org/10.2215/cjn.05230513 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028342587
315 rdf:type schema:CreativeWork
316 https://doi.org/10.2215/cjn.08410814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053082662
317 rdf:type schema:CreativeWork
318 https://doi.org/10.2215/cjn.09810913 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025752558
319 rdf:type schema:CreativeWork
320 https://doi.org/10.2215/cjn.11861111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036048321
321 rdf:type schema:CreativeWork
322 https://doi.org/10.2337/diabetes.54.11.3252 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046542721
323 rdf:type schema:CreativeWork
324 https://doi.org/10.4065/mcp.2010.0336 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015539077
325 rdf:type schema:CreativeWork
326 https://doi.org/10.5527/wjn.v3.i4.210 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072935333
327 rdf:type schema:CreativeWork
328 https://www.grid.ac/institutes/grid.34477.33 schema:alternateName University of Washington
329 schema:name Division of Metabolism, Endocrinology, and Nutrition, University of Washington, Seattle, WA, USA
330 Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA
331 University of Washington School of Medicine, Seattle, WA, USA
332 VA Puget Sound Health Care System, Seattle, WA, USA
333 rdf:type schema:Organization
334 https://www.grid.ac/institutes/grid.413919.7 schema:alternateName VA Puget Sound Health Care System
335 schema:name Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA, USA
336 VA Puget Sound Health Care System, Seattle, WA, USA
337 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...