Association study between KIR polymorphisms and rheumatoid arthritis disease: an updated meta-analysis View Full Text


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Article Info

DATE

2019-12

AUTHORS

Hamideh Aghaei, Shayan Mostafaei, Saeed Aslani, Ahmadreza Jamshidi, Mahdi Mahmoudi

ABSTRACT

BACKGROUND: Currently published studies investigating association between the killer cell immunoglobulin-like receptor (KIR) gene polymorphisms and rheumatoid arthritis (RA) reported inconsistent and contradictory results. Hence, we aim to carry out this comprehensive meta-analysis of all eligible studies meeting the inclusion criteria to achieve precise and comprehensive relationships between genetic variations in KIR gene cluster and risk of RA. METHODS: Databases of Medline/PubMed and Scopus were searched to investigate case-control studies prior to May 2018. The associations between KIR gene polymorphisms and RA susceptibility were analyzed by computing the odds ratio (OR) and 95% confidence interval (95% CI) for each study. RESULTS: A total of 11 comparative case-control studies involving 1847 RA patients and 2409 healthy individuals were included in this meta-analysis. Four significant associations of 2DL3 (OR = 0.591, 95% CI = 0.351-0.994; P = 0.047), 2DL5 (OR = 0.716, 95% CI = 0.601-0.853; P < 0.001), 2DS5 (OR = 0.623, 95% CI = 0.393-0.988; P = 0.045), and 3DL3 (OR = 0.324, 95% CI = 0.129-0.814; P = 0.016) genes with decreased RA risk were discovered in this meta-analysis. Although, other KIR receptors including 2DL1, 2DL2, 2DL4, 3DL1, 3DL2, 3DS1, 2DS1-2DS4, and two pseudo gens of 2DP1 and 3DP1 displayed no significant association with predisposition to RA. CONCLUSIONS: These findings provide reliable evidence that 2DL3, 2DL5, 3DL3, and 2DS5 might have a potential protective role for RA. More... »

PAGES

24

References to SciGraph publications

  • 2017-12. Epigenetic involvement in etiopathogenesis and implications in treatment of systemic lupus erythematous in INFLAMMATION RESEARCH
  • 2017-01. Update on the genetic architecture of rheumatoid arthritis in NATURE REVIEWS RHEUMATOLOGY
  • 2011-08. Doenças reumatológicas autoimunes e sua associação com os genes killer immunoglobulin-like receptors in ADVANCES IN RHEUMATOLOGY
  • 2017-10. Promoter hypermethylation of BCL11B gene correlates with downregulation of gene transcription in ankylosing spondylitis patients in GENES & IMMUNITY
  • 2010-09. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses in EUROPEAN JOURNAL OF EPIDEMIOLOGY
  • 2016-11. Genetic markers as therapeutic target in rheumatoid arthritis: A game changer in clinical therapy? in RHEUMATOLOGY INTERNATIONAL
  • 2017-03. Epigenetic Modifications and Therapy in Multiple Sclerosis in NEUROMOLECULAR MEDICINE
  • 2007-12. Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis in GENES & IMMUNITY
  • 2007-06. Cytokines in the pathogenesis of rheumatoid arthritis in NATURE REVIEWS IMMUNOLOGY
  • 2013-08. Natural killer cells in human autoimmune disorders in ARTHRITIS RESEARCH & THERAPY
  • 2008-12. KIR haplotypes defined by segregation analysis in 59 Centre d’Etude Polymorphisme Humain (CEPH) families in IMMUNOGENETICS
  • 2017-04. Analysis of killer cell immunoglobulin-like receptors (KIRs) and their HLA ligand genes polymorphisms in Iranian patients with systemic sclerosis in CLINICAL RHEUMATOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12881-019-0754-6

    DOI

    http://dx.doi.org/10.1186/s12881-019-0754-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1111768595

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30696403


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