Bordetella bronchiseptica pneumonia in a patient with lung cancer; a case report of a rare infection View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-09-25

AUTHORS

Manlio Monti, Danila Diano, Francesco Allegrini, Angelo Delmonte, Valentina Fausti, Paola Cravero, Giulia Marcantognini, Giovanni Luca Frassineti

ABSTRACT

BackgroundBordetella bronchiseptica (B.bronchiseptica) is a frequent cause of respiratory infections in animals but rarely causes serious infection in humans. We present a rare case of B. bronchiseptica pneumonia in a patient with lung cancer.Case presentationA 52-year-old white male with non small cell lung cancer developed fever during treatment with nivolumab. A persistent productive cough and a deterioration in his clinical condition led to his hospitalization for evaluation. Bronchoscopy was performed and a diagnosis of B. bronchiseptica pneumonia was made. The infection was successfully managed by antiobiotic therapy.ConclusionsB. bronchiseptica is a pathogen that can cause serious infection in humans, especially in immunocompromised or immunoincompetent individuals. In our patient it showed unusual resistance to cephalosporins and poor sensitivity to amikacin. To our knowledge this is the first case of such an infection in a lung cancer patient undergoing treatment with nivolumab. When B. bronchiseptica is identified, the possibility of a nosocomial transmission must be considered. More... »

PAGES

644

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12879-017-2736-7

DOI

http://dx.doi.org/10.1186/s12879-017-2736-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091917999

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28946850


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