Acute rhabdomyolysis and delayed pericardial effusion in an Italian patient with Ebola virus disease: a case report View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Emanuele Nicastri, Antonio Brucato, Nicola Petrosillo, Gianluigi Biava, Timothy M. Uyeki, Giuseppe Ippolito, INMI’s Ebola Team

ABSTRACT

BACKGROUND: During the 2013-2016 West Africa Ebola virus disease (EVD) epidemic, some EVD patients, mostly health care workers, were evacuated to Europe and the USA. CASE PRESENTATION: In May 2015, a 37-year old male nurse contracted Ebola virus disease in Sierra Leone. After Ebola virus detection in plasma, he was medically-evacuated to Italy. At admission, rhabdomyolysis was clinically and laboratory-diagnosed and was treated with aggressive hydration, oral favipiravir and intravenous investigational monoclonal antibodies against Ebola virus. The recovery clinical phase was complicated by a febrile thrombocytopenic syndrome with pericardial effusion treated with corticosteroids for 10 days and indomethacin for 2 months. No evidence of recurrence is reported. CONCLUSIONS: A febrile thrombocytopenic syndrome with pericardial effusion during the recovery phase of EVD appears to be uncommon. Clinical improvement with corticosteroid treatment suggests that an immune-mediated mechanism contributed to the pericardial effusion. More... »

PAGES

597

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12879-017-2689-x

DOI

http://dx.doi.org/10.1186/s12879-017-2689-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1091370981

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28854896


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