Ventricular assist devices as bridge to heart transplantation: impact on post-transplant infections View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-07-08

AUTHORS

Delphine Héquet, Georg Kralidis, Thierry Carrel, Alexia Cusini, Christian Garzoni, Roger Hullin, Pascal R. Meylan, Paul Mohacsi, Nicolas J. Mueller, Frank Ruschitzka, Piergiorgio Tozzi, Christian van Delden, Maja Weisser, Markus J. Wilhelm, Manuel Pascual, Oriol Manuel, Swiss Transplant Cohort Study (STCS)

ABSTRACT

BackgroundVentricular assist devices (VAD) are valuable options for patients with heart failure awaiting cardiac transplantation. We assessed the impact of pre-transplant VAD implantation on the incidence of post-transplant infections in a nationwide cohort of heart transplant recipients.MethodsHeart transplant recipients included in the Swiss Transplant Cohort Study between May 2008 and December 2012 were analyzed. Cumulative incidence curves were used to calculate the incidence of bacterial or Candida infections (primary endpoint) and of other infections (secondary endpoint) after transplant. Cox regression models treating death as a competing risk were used to identify risk factors for the development of infection after transplant.ResultsOverall, 119 patients were included in the study, 35 with a VAD and 84 without VAD. Cumulative incidences of post-transplant bacterial or Candida infections were 37.7 % in VAD patients and 40.4 % in non-VAD patients. In multivariate analysis, the use of cotrimoxazole prophylaxis was the only variable associated with bacterial/Candida infections after transplant (HR 0.29 [95 % CI 0.15-0.57], p < 0.001), but presence of a VAD was not (HR 0.94, [95 % CI 0.38-2.32], p = 0.89, for continuous-flow devices, and HR 0.45 [0.15 – 1.34], p = 0.15, for other devices). Risk for post-transplant viral and all fungal infections was not increased in patients with VAD. One-year survival was 82.9 % (29/35) in the VAD group and 82.1 % (69/84) in the non-VAD group. All 6 patients in the VAD group that died after transplant had a history of pre-transplant VAD infection.ConclusionIn this nationwide cohort of heart transplant recipients, the presence of VAD at the time of transplant had no influence on the development of post-transplant infections. More... »

PAGES

321

Journal

TITLE

BMC Infectious Diseases

ISSUE

1

VOLUME

16

Author Affiliations

  • Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
  • Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland
  • Clinic for Cardiovascular Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
  • Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
  • Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese, Lugano, Switzerland
  • Department of Medicine, Service of Cardiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
  • Institute of Microbiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
  • Bern University Hospital and University of Bern, Bern, Switzerland
  • Division of Infectious Diseases and Hospital Epidemiology, University Hospital, University of Zurich, Zurich, Switzerland
  • Department of Cardiology, Cardiovascular Center, University Hospital, University of Zurich, Zurich, Switzerland
  • Department of Cardiovascular Surgery, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
  • Transplant Infectious Diseases Unit, University Hospitals Geneva, Geneva, Switzerland
  • Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
  • Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland
  • Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
  • Infectious Diseases Service and Transplantation Center, University Hospital and University of Lausanne, BH 10/553, CHUV, Lausanne, Switzerland
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12879-016-1658-0

    DOI

    http://dx.doi.org/10.1186/s12879-016-1658-0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1012437319

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27391967


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Cardiorespiratory Medicine and Haematology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bacterial Infections", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cohort Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Heart Failure", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Heart Transplantation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Heart-Assist Devices", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Incidence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Multivariate Analysis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mycoses", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Postoperative Complications", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Proportional Hazards Models", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Retrospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Virus Diseases", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.9851.5", 
              "name": [
                "Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
                "Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "H\u00e9quet", 
            "givenName": "Delphine", 
            "id": "sg:person.0717624737.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717624737.97"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.410567.1", 
              "name": [
                "Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kralidis", 
            "givenName": "Georg", 
            "id": "sg:person.0614304726.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614304726.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Clinic for Cardiovascular Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.411656.1", 
              "name": [
                "Clinic for Cardiovascular Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Carrel", 
            "givenName": "Thierry", 
            "id": "sg:person.01250703550.03", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250703550.03"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.411656.1", 
              "name": [
                "Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cusini", 
            "givenName": "Alexia", 
            "id": "sg:person.01061536656.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061536656.80"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese, Lugano, Switzerland", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland", 
                "Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese, Lugano, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Garzoni", 
            "givenName": "Christian", 
            "id": "sg:person.0776426700.95", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776426700.95"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Medicine, Service of Cardiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.9851.5", 
              "name": [
                "Department of Medicine, Service of Cardiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hullin", 
            "givenName": "Roger", 
            "id": "sg:person.0733025350.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733025350.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Microbiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.9851.5", 
              "name": [
                "Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
                "Institute of Microbiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Meylan", 
            "givenName": "Pascal R.", 
            "id": "sg:person.01336350503.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336350503.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Bern University Hospital and University of Bern, Bern, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.411656.1", 
              "name": [
                "Bern University Hospital and University of Bern, Bern, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mohacsi", 
            "givenName": "Paul", 
            "id": "sg:person.01123415640.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123415640.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Infectious Diseases and Hospital Epidemiology, University Hospital, University of Zurich, Zurich, Switzerland", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Division of Infectious Diseases and Hospital Epidemiology, University Hospital, University of Zurich, Zurich, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mueller", 
            "givenName": "Nicolas J.", 
            "id": "sg:person.01305722520.92", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305722520.92"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Cardiology, Cardiovascular Center, University Hospital, University of Zurich, Zurich, Switzerland", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Cardiology, Cardiovascular Center, University Hospital, University of Zurich, Zurich, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ruschitzka", 
            "givenName": "Frank", 
            "id": "sg:person.01103006423.90", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103006423.90"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Cardiovascular Surgery, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.9851.5", 
              "name": [
                "Department of Cardiovascular Surgery, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tozzi", 
            "givenName": "Piergiorgio", 
            "id": "sg:person.01343221024.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343221024.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Transplant Infectious Diseases Unit, University Hospitals Geneva, Geneva, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.150338.c", 
              "name": [
                "Transplant Infectious Diseases Unit, University Hospitals Geneva, Geneva, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "van Delden", 
            "givenName": "Christian", 
            "id": "sg:person.01120743117.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120743117.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.410567.1", 
              "name": [
                "Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weisser", 
            "givenName": "Maja", 
            "id": "sg:person.01342314314.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342314314.76"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.412004.3", 
              "name": [
                "Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wilhelm", 
            "givenName": "Markus J.", 
            "id": "sg:person.01321032122.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321032122.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.9851.5", 
              "name": [
                "Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pascual", 
            "givenName": "Manuel", 
            "id": "sg:person.01205263315.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205263315.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Infectious Diseases Service and Transplantation Center, University Hospital and University of Lausanne, BH 10/553, CHUV, Lausanne, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.9851.5", 
              "name": [
                "Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
                "Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland", 
                "Infectious Diseases Service and Transplantation Center, University Hospital and University of Lausanne, BH 10/553, CHUV, Lausanne, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Manuel", 
            "givenName": "Oriol", 
            "id": "sg:person.01311627331.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311627331.51"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Swiss Transplant Cohort Study (STCS)", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s10654-012-9754-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026952332", 
              "https://doi.org/10.1007/s10654-012-9754-y"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2016-07-08", 
        "datePublishedReg": "2016-07-08", 
        "description": "BackgroundVentricular assist devices (VAD) are valuable options for patients with heart failure awaiting cardiac transplantation. We assessed the impact of pre-transplant VAD implantation on the incidence of post-transplant infections in a nationwide cohort of heart transplant recipients.MethodsHeart transplant recipients included in the Swiss Transplant Cohort Study between May 2008 and December 2012 were analyzed. Cumulative incidence curves were used to calculate the incidence of bacterial or Candida infections (primary endpoint) and of other infections (secondary endpoint) after transplant. Cox regression models treating death as a competing risk were used to identify risk factors for the development of infection after transplant.ResultsOverall, 119 patients were included in the study, 35 with a VAD and 84 without VAD. Cumulative incidences of post-transplant bacterial or Candida infections were 37.7\u00a0% in VAD patients and 40.4\u00a0% in non-VAD patients. In multivariate analysis, the use of cotrimoxazole prophylaxis was the only variable associated with bacterial/Candida infections after transplant (HR 0.29 [95 % CI 0.15-0.57], p\u2009<\u20090.001), but presence of a VAD was not (HR 0.94, [95 % CI 0.38-2.32], p\u2009=\u20090.89, for continuous-flow devices, and HR 0.45 [0.15 \u2013 1.34], p\u2009=\u20090.15, for other devices). Risk for post-transplant viral and all fungal infections was not increased in patients with VAD. One-year survival was 82.9\u00a0% (29/35) in the VAD group and 82.1\u00a0% (69/84) in the non-VAD group. All 6 patients in the VAD group that died after transplant had a history of pre-transplant VAD infection.ConclusionIn this nationwide cohort of heart transplant recipients, the presence of VAD at the time of transplant had no influence on the development of post-transplant infections.", 
        "genre": "article", 
        "id": "sg:pub.10.1186/s12879-016-1658-0", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.5236581", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.5229587", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1024946", 
            "issn": [
              "1471-2334"
            ], 
            "name": "BMC Infectious Diseases", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "16"
          }
        ], 
        "keywords": [
          "post-transplant infections", 
          "heart transplant recipients", 
          "transplant recipients", 
          "Candida infections", 
          "nationwide cohort", 
          "VAD group", 
          "assist device", 
          "Swiss Transplant Cohort Study", 
          "non-VAD patients", 
          "non-VAD group", 
          "presence of VAD", 
          "One-year survival", 
          "time of transplant", 
          "development of infection", 
          "cumulative incidence curves", 
          "ventricular assist device", 
          "cotrimoxazole prophylaxis", 
          "VAD infections", 
          "cardiac transplantation", 
          "heart transplantation", 
          "VAD implantation", 
          "cohort study", 
          "cumulative incidence", 
          "heart failure", 
          "VaD patients", 
          "risk factors", 
          "patients", 
          "transplant", 
          "multivariate analysis", 
          "infection", 
          "fungal infections", 
          "VAD", 
          "incidence curves", 
          "valuable option", 
          "incidence", 
          "only variable", 
          "recipients", 
          "transplantation", 
          "cohort", 
          "regression models", 
          "risk", 
          "group", 
          "prophylaxis", 
          "ResultsOverall", 
          "ConclusionIn", 
          "death", 
          "survival", 
          "viral", 
          "implantation", 
          "study", 
          "failure", 
          "options", 
          "presence", 
          "factors", 
          "history", 
          "development", 
          "use", 
          "variables", 
          "impact", 
          "time", 
          "curves", 
          "analysis", 
          "influence", 
          "model", 
          "devices", 
          "bridge"
        ], 
        "name": "Ventricular assist devices as bridge to heart transplantation: impact on post-transplant infections", 
        "pagination": "321", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1012437319"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s12879-016-1658-0"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "27391967"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s12879-016-1658-0", 
          "https://app.dimensions.ai/details/publication/pub.1012437319"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:42", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_705.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1186/s12879-016-1658-0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12879-016-1658-0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12879-016-1658-0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12879-016-1658-0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12879-016-1658-0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    355 TRIPLES      21 PREDICATES      111 URIs      102 LITERALS      26 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s12879-016-1658-0 schema:about N03cccbc0c76c4470a34aad4b6eb81268
    2 N09bd8e97bfec4c8990f30185e76dbe8f
    3 N1c3d3bfb5ced478f80b40e141f3292f2
    4 N2db7463c69304903b4549c2d9ca7f7ec
    5 N301f4fcd53f24638a17137db27500474
    6 N368064c15c6d4ed3b032d18a538e1ef8
    7 N42eaee040bf34a42adad8b5dc3cc4873
    8 N4be7dc78ad00480ba8eafff81a3819c4
    9 N7707295420e9438aaff59c72036f7d2f
    10 N77cbaaf74a5247a689e1e9bdfcf07d76
    11 N7c343afc77be4a5ba525a36330c81d0f
    12 N86b67b10599049ca970c36a92f848ed3
    13 N8fcc064e0fa340958cc8a259e23522f7
    14 N9b11d5e60ff743bc83fab0de95d3608b
    15 Na3c27cc2e94644d0b679d24c6de1ea83
    16 Nbb0d96524d2b427da7fc6293a038df25
    17 Nc84b0bf15ce0457c8a728a36eb4a2023
    18 Ne4b839765684423f81bed5ce8e382b7d
    19 Nf9fac5a8ff694f738498352390aba9b0
    20 anzsrc-for:11
    21 anzsrc-for:1102
    22 schema:author Nfd56aee855224239a2ec1793d27d55bc
    23 schema:citation sg:pub.10.1007/s10654-012-9754-y
    24 schema:datePublished 2016-07-08
    25 schema:datePublishedReg 2016-07-08
    26 schema:description BackgroundVentricular assist devices (VAD) are valuable options for patients with heart failure awaiting cardiac transplantation. We assessed the impact of pre-transplant VAD implantation on the incidence of post-transplant infections in a nationwide cohort of heart transplant recipients.MethodsHeart transplant recipients included in the Swiss Transplant Cohort Study between May 2008 and December 2012 were analyzed. Cumulative incidence curves were used to calculate the incidence of bacterial or Candida infections (primary endpoint) and of other infections (secondary endpoint) after transplant. Cox regression models treating death as a competing risk were used to identify risk factors for the development of infection after transplant.ResultsOverall, 119 patients were included in the study, 35 with a VAD and 84 without VAD. Cumulative incidences of post-transplant bacterial or Candida infections were 37.7 % in VAD patients and 40.4 % in non-VAD patients. In multivariate analysis, the use of cotrimoxazole prophylaxis was the only variable associated with bacterial/Candida infections after transplant (HR 0.29 [95 % CI 0.15-0.57], p < 0.001), but presence of a VAD was not (HR 0.94, [95 % CI 0.38-2.32], p = 0.89, for continuous-flow devices, and HR 0.45 [0.15 – 1.34], p = 0.15, for other devices). Risk for post-transplant viral and all fungal infections was not increased in patients with VAD. One-year survival was 82.9 % (29/35) in the VAD group and 82.1 % (69/84) in the non-VAD group. All 6 patients in the VAD group that died after transplant had a history of pre-transplant VAD infection.ConclusionIn this nationwide cohort of heart transplant recipients, the presence of VAD at the time of transplant had no influence on the development of post-transplant infections.
    27 schema:genre article
    28 schema:isAccessibleForFree true
    29 schema:isPartOf N14eba1b2dbf84eac8f20fefe8a6785fc
    30 Na604b1d3fde44ac4ba8bfb6724241ef3
    31 sg:journal.1024946
    32 schema:keywords Candida infections
    33 ConclusionIn
    34 One-year survival
    35 ResultsOverall
    36 Swiss Transplant Cohort Study
    37 VAD
    38 VAD group
    39 VAD implantation
    40 VAD infections
    41 VaD patients
    42 analysis
    43 assist device
    44 bridge
    45 cardiac transplantation
    46 cohort
    47 cohort study
    48 cotrimoxazole prophylaxis
    49 cumulative incidence
    50 cumulative incidence curves
    51 curves
    52 death
    53 development
    54 development of infection
    55 devices
    56 factors
    57 failure
    58 fungal infections
    59 group
    60 heart failure
    61 heart transplant recipients
    62 heart transplantation
    63 history
    64 impact
    65 implantation
    66 incidence
    67 incidence curves
    68 infection
    69 influence
    70 model
    71 multivariate analysis
    72 nationwide cohort
    73 non-VAD group
    74 non-VAD patients
    75 only variable
    76 options
    77 patients
    78 post-transplant infections
    79 presence
    80 presence of VAD
    81 prophylaxis
    82 recipients
    83 regression models
    84 risk
    85 risk factors
    86 study
    87 survival
    88 time
    89 time of transplant
    90 transplant
    91 transplant recipients
    92 transplantation
    93 use
    94 valuable option
    95 variables
    96 ventricular assist device
    97 viral
    98 schema:name Ventricular assist devices as bridge to heart transplantation: impact on post-transplant infections
    99 schema:pagination 321
    100 schema:productId N2f6efaf46e9e4dfbb2c9a71033f2f661
    101 N55ee68beee6b4ef5b8be0954e5ba1fd7
    102 Nb757cde4cfda42e097188e394cebc496
    103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012437319
    104 https://doi.org/10.1186/s12879-016-1658-0
    105 schema:sdDatePublished 2022-10-01T06:42
    106 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    107 schema:sdPublisher N58a71daef93f4ce8955370815a512526
    108 schema:url https://doi.org/10.1186/s12879-016-1658-0
    109 sgo:license sg:explorer/license/
    110 sgo:sdDataset articles
    111 rdf:type schema:ScholarlyArticle
    112 N02bb266cba954cdfa49e49d61688aef6 rdf:first sg:person.01336350503.09
    113 rdf:rest N0add68ddb6da46228a5ba637b98e0b75
    114 N03cccbc0c76c4470a34aad4b6eb81268 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Postoperative Complications
    116 rdf:type schema:DefinedTerm
    117 N09bd8e97bfec4c8990f30185e76dbe8f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Multivariate Analysis
    119 rdf:type schema:DefinedTerm
    120 N0add68ddb6da46228a5ba637b98e0b75 rdf:first sg:person.01123415640.24
    121 rdf:rest N9e5639d774d74e3bb1ec30472e8a77fb
    122 N14eba1b2dbf84eac8f20fefe8a6785fc schema:issueNumber 1
    123 rdf:type schema:PublicationIssue
    124 N1c3d3bfb5ced478f80b40e141f3292f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Aged
    126 rdf:type schema:DefinedTerm
    127 N2db7463c69304903b4549c2d9ca7f7ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    128 schema:name Adult
    129 rdf:type schema:DefinedTerm
    130 N2f6efaf46e9e4dfbb2c9a71033f2f661 schema:name doi
    131 schema:value 10.1186/s12879-016-1658-0
    132 rdf:type schema:PropertyValue
    133 N301f4fcd53f24638a17137db27500474 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Risk Factors
    135 rdf:type schema:DefinedTerm
    136 N31164691ed644860962841a57179a0e0 rdf:first sg:person.01103006423.90
    137 rdf:rest Nf6822b93d10f4365925f3bca9bfa0c78
    138 N368064c15c6d4ed3b032d18a538e1ef8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    139 schema:name Incidence
    140 rdf:type schema:DefinedTerm
    141 N3f0fe7a8b4ea439494d912c7b5af55bc rdf:first sg:person.01321032122.25
    142 rdf:rest Nb4b43b699bd94b02993a5459b9bc93ba
    143 N42eaee040bf34a42adad8b5dc3cc4873 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Humans
    145 rdf:type schema:DefinedTerm
    146 N4be7dc78ad00480ba8eafff81a3819c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    147 schema:name Middle Aged
    148 rdf:type schema:DefinedTerm
    149 N4d200a99f16549818c640f1652065126 rdf:first sg:person.0733025350.11
    150 rdf:rest N02bb266cba954cdfa49e49d61688aef6
    151 N55ee68beee6b4ef5b8be0954e5ba1fd7 schema:name dimensions_id
    152 schema:value pub.1012437319
    153 rdf:type schema:PropertyValue
    154 N58a71daef93f4ce8955370815a512526 schema:name Springer Nature - SN SciGraph project
    155 rdf:type schema:Organization
    156 N7707295420e9438aaff59c72036f7d2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    157 schema:name Bacterial Infections
    158 rdf:type schema:DefinedTerm
    159 N77cbaaf74a5247a689e1e9bdfcf07d76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    160 schema:name Cohort Studies
    161 rdf:type schema:DefinedTerm
    162 N7b521bb9b5404b8eb3fb74a773c66798 rdf:first sg:person.01061536656.80
    163 rdf:rest N8184c46591da4fb39ccdff0a3d164658
    164 N7c343afc77be4a5ba525a36330c81d0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    165 schema:name Heart Transplantation
    166 rdf:type schema:DefinedTerm
    167 N8184c46591da4fb39ccdff0a3d164658 rdf:first sg:person.0776426700.95
    168 rdf:rest N4d200a99f16549818c640f1652065126
    169 N86b67b10599049ca970c36a92f848ed3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    170 schema:name Male
    171 rdf:type schema:DefinedTerm
    172 N8ce672b7bfaa4d648268213b47e0a96a rdf:first sg:person.01311627331.51
    173 rdf:rest N939986b5e9a34da78efbf2d6f0d60717
    174 N8fcc064e0fa340958cc8a259e23522f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    175 schema:name Heart Failure
    176 rdf:type schema:DefinedTerm
    177 N939986b5e9a34da78efbf2d6f0d60717 rdf:first N9ab1ab899adb4462bc9e7790e043861c
    178 rdf:rest rdf:nil
    179 N974480b84f264ccc9cbe24ef5cca8a1a rdf:first sg:person.01250703550.03
    180 rdf:rest N7b521bb9b5404b8eb3fb74a773c66798
    181 N9ab1ab899adb4462bc9e7790e043861c schema:familyName Swiss Transplant Cohort Study (STCS)
    182 rdf:type schema:Person
    183 N9b11d5e60ff743bc83fab0de95d3608b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    184 schema:name Proportional Hazards Models
    185 rdf:type schema:DefinedTerm
    186 N9e5639d774d74e3bb1ec30472e8a77fb rdf:first sg:person.01305722520.92
    187 rdf:rest N31164691ed644860962841a57179a0e0
    188 Na1dbe69628f54307b0b88d5c2abe0362 rdf:first sg:person.0614304726.43
    189 rdf:rest N974480b84f264ccc9cbe24ef5cca8a1a
    190 Na3c27cc2e94644d0b679d24c6de1ea83 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    191 schema:name Heart-Assist Devices
    192 rdf:type schema:DefinedTerm
    193 Na604b1d3fde44ac4ba8bfb6724241ef3 schema:volumeNumber 16
    194 rdf:type schema:PublicationVolume
    195 Nb4b43b699bd94b02993a5459b9bc93ba rdf:first sg:person.01205263315.38
    196 rdf:rest N8ce672b7bfaa4d648268213b47e0a96a
    197 Nb757cde4cfda42e097188e394cebc496 schema:name pubmed_id
    198 schema:value 27391967
    199 rdf:type schema:PropertyValue
    200 Nbb0d96524d2b427da7fc6293a038df25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    201 schema:name Retrospective Studies
    202 rdf:type schema:DefinedTerm
    203 Nc84b0bf15ce0457c8a728a36eb4a2023 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    204 schema:name Female
    205 rdf:type schema:DefinedTerm
    206 Nc8d0f62b98234aff989ab049999e8a8c rdf:first sg:person.01342314314.76
    207 rdf:rest N3f0fe7a8b4ea439494d912c7b5af55bc
    208 Ne4b839765684423f81bed5ce8e382b7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    209 schema:name Virus Diseases
    210 rdf:type schema:DefinedTerm
    211 Nf6822b93d10f4365925f3bca9bfa0c78 rdf:first sg:person.01343221024.32
    212 rdf:rest Nff6f32db6cdc4c56a55bcf9226914c7c
    213 Nf9fac5a8ff694f738498352390aba9b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    214 schema:name Mycoses
    215 rdf:type schema:DefinedTerm
    216 Nfd56aee855224239a2ec1793d27d55bc rdf:first sg:person.0717624737.97
    217 rdf:rest Na1dbe69628f54307b0b88d5c2abe0362
    218 Nff6f32db6cdc4c56a55bcf9226914c7c rdf:first sg:person.01120743117.40
    219 rdf:rest Nc8d0f62b98234aff989ab049999e8a8c
    220 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    221 schema:name Medical and Health Sciences
    222 rdf:type schema:DefinedTerm
    223 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
    224 schema:name Cardiorespiratory Medicine and Haematology
    225 rdf:type schema:DefinedTerm
    226 sg:grant.5229587 http://pending.schema.org/fundedItem sg:pub.10.1186/s12879-016-1658-0
    227 rdf:type schema:MonetaryGrant
    228 sg:grant.5236581 http://pending.schema.org/fundedItem sg:pub.10.1186/s12879-016-1658-0
    229 rdf:type schema:MonetaryGrant
    230 sg:journal.1024946 schema:issn 1471-2334
    231 schema:name BMC Infectious Diseases
    232 schema:publisher Springer Nature
    233 rdf:type schema:Periodical
    234 sg:person.01061536656.80 schema:affiliation grid-institutes:grid.411656.1
    235 schema:familyName Cusini
    236 schema:givenName Alexia
    237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01061536656.80
    238 rdf:type schema:Person
    239 sg:person.01103006423.90 schema:affiliation grid-institutes:None
    240 schema:familyName Ruschitzka
    241 schema:givenName Frank
    242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103006423.90
    243 rdf:type schema:Person
    244 sg:person.01120743117.40 schema:affiliation grid-institutes:grid.150338.c
    245 schema:familyName van Delden
    246 schema:givenName Christian
    247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120743117.40
    248 rdf:type schema:Person
    249 sg:person.01123415640.24 schema:affiliation grid-institutes:grid.411656.1
    250 schema:familyName Mohacsi
    251 schema:givenName Paul
    252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123415640.24
    253 rdf:type schema:Person
    254 sg:person.01205263315.38 schema:affiliation grid-institutes:grid.9851.5
    255 schema:familyName Pascual
    256 schema:givenName Manuel
    257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01205263315.38
    258 rdf:type schema:Person
    259 sg:person.01250703550.03 schema:affiliation grid-institutes:grid.411656.1
    260 schema:familyName Carrel
    261 schema:givenName Thierry
    262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01250703550.03
    263 rdf:type schema:Person
    264 sg:person.01305722520.92 schema:affiliation grid-institutes:None
    265 schema:familyName Mueller
    266 schema:givenName Nicolas J.
    267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305722520.92
    268 rdf:type schema:Person
    269 sg:person.01311627331.51 schema:affiliation grid-institutes:grid.9851.5
    270 schema:familyName Manuel
    271 schema:givenName Oriol
    272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311627331.51
    273 rdf:type schema:Person
    274 sg:person.01321032122.25 schema:affiliation grid-institutes:grid.412004.3
    275 schema:familyName Wilhelm
    276 schema:givenName Markus J.
    277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01321032122.25
    278 rdf:type schema:Person
    279 sg:person.01336350503.09 schema:affiliation grid-institutes:grid.9851.5
    280 schema:familyName Meylan
    281 schema:givenName Pascal R.
    282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336350503.09
    283 rdf:type schema:Person
    284 sg:person.01342314314.76 schema:affiliation grid-institutes:grid.410567.1
    285 schema:familyName Weisser
    286 schema:givenName Maja
    287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342314314.76
    288 rdf:type schema:Person
    289 sg:person.01343221024.32 schema:affiliation grid-institutes:grid.9851.5
    290 schema:familyName Tozzi
    291 schema:givenName Piergiorgio
    292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343221024.32
    293 rdf:type schema:Person
    294 sg:person.0614304726.43 schema:affiliation grid-institutes:grid.410567.1
    295 schema:familyName Kralidis
    296 schema:givenName Georg
    297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614304726.43
    298 rdf:type schema:Person
    299 sg:person.0717624737.97 schema:affiliation grid-institutes:grid.9851.5
    300 schema:familyName Héquet
    301 schema:givenName Delphine
    302 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717624737.97
    303 rdf:type schema:Person
    304 sg:person.0733025350.11 schema:affiliation grid-institutes:grid.9851.5
    305 schema:familyName Hullin
    306 schema:givenName Roger
    307 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0733025350.11
    308 rdf:type schema:Person
    309 sg:person.0776426700.95 schema:affiliation grid-institutes:None
    310 schema:familyName Garzoni
    311 schema:givenName Christian
    312 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776426700.95
    313 rdf:type schema:Person
    314 sg:pub.10.1007/s10654-012-9754-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1026952332
    315 https://doi.org/10.1007/s10654-012-9754-y
    316 rdf:type schema:CreativeWork
    317 grid-institutes:None schema:alternateName Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese, Lugano, Switzerland
    318 Department of Cardiology, Cardiovascular Center, University Hospital, University of Zurich, Zurich, Switzerland
    319 Division of Infectious Diseases and Hospital Epidemiology, University Hospital, University of Zurich, Zurich, Switzerland
    320 schema:name Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese, Lugano, Switzerland
    321 Department of Cardiology, Cardiovascular Center, University Hospital, University of Zurich, Zurich, Switzerland
    322 Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    323 Division of Infectious Diseases and Hospital Epidemiology, University Hospital, University of Zurich, Zurich, Switzerland
    324 rdf:type schema:Organization
    325 grid-institutes:grid.150338.c schema:alternateName Transplant Infectious Diseases Unit, University Hospitals Geneva, Geneva, Switzerland
    326 schema:name Transplant Infectious Diseases Unit, University Hospitals Geneva, Geneva, Switzerland
    327 rdf:type schema:Organization
    328 grid-institutes:grid.410567.1 schema:alternateName Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
    329 Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland
    330 schema:name Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
    331 Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland
    332 rdf:type schema:Organization
    333 grid-institutes:grid.411656.1 schema:alternateName Bern University Hospital and University of Bern, Bern, Switzerland
    334 Clinic for Cardiovascular Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    335 Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    336 schema:name Bern University Hospital and University of Bern, Bern, Switzerland
    337 Clinic for Cardiovascular Surgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    338 Department of Infectious Diseases, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    339 rdf:type schema:Organization
    340 grid-institutes:grid.412004.3 schema:alternateName Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland
    341 schema:name Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland
    342 rdf:type schema:Organization
    343 grid-institutes:grid.9851.5 schema:alternateName Department of Cardiovascular Surgery, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    344 Department of Medicine, Service of Cardiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    345 Infectious Diseases Service and Transplantation Center, University Hospital and University of Lausanne, BH 10/553, CHUV, Lausanne, Switzerland
    346 Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    347 Institute of Microbiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    348 Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    349 schema:name Department of Cardiovascular Surgery, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    350 Department of Medicine, Service of Cardiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    351 Infectious Diseases Service and Transplantation Center, University Hospital and University of Lausanne, BH 10/553, CHUV, Lausanne, Switzerland
    352 Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    353 Institute of Microbiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    354 Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland
    355 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...