Anticoagulant treatment in German family practices – screening results from a cluster randomized controlled trial View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-12

AUTHORS

Lisa-R Ulrich, Karola Mergenthal, Juliana J Petersen, Ina Roehl, Sandra Rauck, Birgit Kemperdick, Sylvia Schulz-Rothe, Andrea Berghold, Andrea Siebenhofer

ABSTRACT

BACKGROUND: Oral anticoagulation (OAC) with coumarins and new anticoagulants are highly effective in preventing thromboembolic complications. However, some studies indicate that over- and under-treatment with anticoagulants are fairly common. The aim of this paper is to assess the appropriateness of treatment in patients with a long-term indication for OAC, and to describe the corresponding characteristics of such patients on the basis of screening results from the cluster randomized PICANT trial. METHODS: Randomly selected family practices in the federal state of Hesse, Germany, were visited by study team members. Eligible patients were screened using an anonymous patient list that was generated by the general practitioners' software according to predefined instructions. A documentation sheet was filled in for all screened patients. Eligible patients were classified into 3 categories (1: patients with a long-term indication for OAC and taking anticoagulants, 2: patients with a long-term indication for OAC but not taking anticoagulants, 3: patients without a long-term indication for OAC but taking an anticoagulant on a permanent basis). IBM SPSS Statistics 20 was used for descriptive statistical analysis. RESULTS: We screened 2,036 randomly selected, potentially eligible patients from 52 family practices. 275 patients could not be assigned to one of the 3 categories and were therefore not considered for analysis. The final study sample comprised 1,761 screened patients, 1,641 of whom belonged to category 1, 78 to category 2, and 42 to category 3. INR values were available for 1,504 patients of whom 1,013 presented INR values within their therapeutic ranges. The majority of screened patients had very good compliance, as assessed by the general practitioner. New antithrombotic drugs were prescribed in 6.1% of cases. CONCLUSIONS: The screening results showed that a high proportion of patients were receiving appropriate anticoagulation therapy. The numbers of patients with a long-term indication for OAC therapy that were not receiving oral anticoagulants, and without a long-term indication that were receiving OAC, were considerably lower than expected. Most patients take coumarins, and the quality of OAC control is reasonably high. TRIAL REGISTRATION: Current Controlled Trials ISRCTN41847489. More... »

PAGES

170

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12875-014-0170-0

DOI

http://dx.doi.org/10.1186/s12875-014-0170-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022333908

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25344288


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Administration, Oral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anticoagulants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Atrial Fibrillation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Benzimidazoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Coumarins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dabigatran", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Family Practice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Germany", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Guideline Adherence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Valve Prosthesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "International Normalized Ratio", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mass Screening", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Morpholines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Practice Guidelines as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Process Assessment (Health Care)", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pulmonary Embolism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pyrazoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pyridones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rivaroxaban", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Stroke", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thiophenes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thromboembolism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thrombosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Venous Thromboembolism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "beta-Alanine", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ulrich", 
        "givenName": "Lisa-R", 
        "id": "sg:person.01175462162.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175462162.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mergenthal", 
        "givenName": "Karola", 
        "id": "sg:person.0735024423.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735024423.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Petersen", 
        "givenName": "Juliana J", 
        "id": "sg:person.01120414202.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120414202.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roehl", 
        "givenName": "Ina", 
        "id": "sg:person.0634417662.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634417662.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rauck", 
        "givenName": "Sandra", 
        "id": "sg:person.0750646262.80", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750646262.80"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kemperdick", 
        "givenName": "Birgit", 
        "id": "sg:person.0606534216.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606534216.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schulz-Rothe", 
        "givenName": "Sylvia", 
        "id": "sg:person.0746237506.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746237506.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical University of Graz", 
          "id": "https://www.grid.ac/institutes/grid.11598.34", 
          "name": [
            "Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Berghold", 
        "givenName": "Andrea", 
        "id": "sg:person.01370660441.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370660441.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siebenhofer", 
        "givenName": "Andrea", 
        "id": "sg:person.01063613514.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063613514.45"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1136/bmj.330.7492.644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003153124"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-37124-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012141922", 
          "https://doi.org/10.1007/978-3-642-37124-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-37124-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012141922", 
          "https://doi.org/10.1007/978-3-642-37124-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/europace/eur416", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012494146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1748-5908-7-79", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012756155", 
          "https://doi.org/10.1186/1748-5908-7-79"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjmed.2009.11.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014694271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jclinepi.2007.11.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016528221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.11-2288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020246916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/heartjnl-2012-303472", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028986073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(11)61294-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029901058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.108.796185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029965959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.108.796185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029965959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/europace/eus305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030385418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-006-0002-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034830965", 
          "https://doi.org/10.1007/s11239-006-0002-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000063575.17904.4e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037218097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000353484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037965162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.1412s3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044869520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2296-4-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047945540", 
          "https://doi.org/10.1186/1471-2296-4-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/europace/eun369", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050885027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0029-1208103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057181005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1160/th08-06-0361", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063291703"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3238/arztebl.2014.0083", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078879081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083115882", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-12", 
    "datePublishedReg": "2014-12-01", 
    "description": "BACKGROUND: Oral anticoagulation (OAC) with coumarins and new anticoagulants are highly effective in preventing thromboembolic complications. However, some studies indicate that over- and under-treatment with anticoagulants are fairly common. The aim of this paper is to assess the appropriateness of treatment in patients with a long-term indication for OAC, and to describe the corresponding characteristics of such patients on the basis of screening results from the cluster randomized PICANT trial.\nMETHODS: Randomly selected family practices in the federal state of Hesse, Germany, were visited by study team members. Eligible patients were screened using an anonymous patient list that was generated by the general practitioners' software according to predefined instructions. A documentation sheet was filled in for all screened patients. Eligible patients were classified into 3 categories (1: patients with a long-term indication for OAC and taking anticoagulants, 2: patients with a long-term indication for OAC but not taking anticoagulants, 3: patients without a long-term indication for OAC but taking an anticoagulant on a permanent basis). IBM SPSS Statistics 20 was used for descriptive statistical analysis.\nRESULTS: We screened 2,036 randomly selected, potentially eligible patients from 52 family practices. 275 patients could not be assigned to one of the 3 categories and were therefore not considered for analysis. The final study sample comprised 1,761 screened patients, 1,641 of whom belonged to category 1, 78 to category 2, and 42 to category 3. INR values were available for 1,504 patients of whom 1,013 presented INR values within their therapeutic ranges. The majority of screened patients had very good compliance, as assessed by the general practitioner. New antithrombotic drugs were prescribed in 6.1% of cases.\nCONCLUSIONS: The screening results showed that a high proportion of patients were receiving appropriate anticoagulation therapy. The numbers of patients with a long-term indication for OAC therapy that were not receiving oral anticoagulants, and without a long-term indication that were receiving OAC, were considerably lower than expected. Most patients take coumarins, and the quality of OAC control is reasonably high.\nTRIAL REGISTRATION: Current Controlled Trials ISRCTN41847489.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12875-014-0170-0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1024625", 
        "issn": [
          "1471-2296"
        ], 
        "name": "BMC Family Practice", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Anticoagulant treatment in German family practices \u2013 screening results from a cluster randomized controlled trial", 
    "pagination": "170", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "6a66cbe855e5c92c1462a416f1684f0a058f49849f0affb644edc2d82c6b87a1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "25344288"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100967792"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12875-014-0170-0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022333908"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12875-014-0170-0", 
      "https://app.dimensions.ai/details/publication/pub.1022333908"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89804_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2Fs12875-014-0170-0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12875-014-0170-0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12875-014-0170-0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12875-014-0170-0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12875-014-0170-0'


 

This table displays all metadata directly associated to this object as RDF triples.

321 TRIPLES      21 PREDICATES      82 URIs      53 LITERALS      41 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12875-014-0170-0 schema:about N0b4d91341323479db8932b0d6852632a
2 N10b64e563403498ab942c28aba97db8d
3 N1436cdadfe464c1d912626a37c5ef403
4 N17c08c4eecc6457fae99c2b25b6ac16b
5 N20e4671bb35c4009af0b7c36fbe28bfd
6 N292589bd480c45e3807e0dc12ed6332f
7 N3d90b0a7de01452fba8cd24cb5cbd17c
8 N41963b670253455cade0629891d9837d
9 N43b21796472e4ce8b2aeb4a1c4e2abb6
10 N4a986be7feb342968f6f0e0e27aa93e4
11 N57158c102e62436185f1fb827075acd0
12 N58c0e3fa92be42c7bf013d1afef31dd5
13 N5ccc307a11bd4f0aa48d7a3dcfe09865
14 N5f34b95b5f344e62921715a4de23f5aa
15 N60bc47593d66467f8bb8dfbe37aeb012
16 N66b369d2a5714cc89fe414b5542542e7
17 N6b965ce2898e4e44b8c1383f48fce77b
18 N7f005db8f3b0402889a1a07886acfb6e
19 N891149b8a8454604972517f56bf06c60
20 N8d2bc681b3d14637bc6d493e5b49245d
21 Nb6d4e3644482444f921f7380f218eccd
22 Nba808fef9c344bd0b1142fce9d1d6c4e
23 Nbb1fd2de61984c58a021c7569b0e81e6
24 Nc2272194ee904822acfa7139a436744a
25 Nc35692ee2cf947afa3d9f4d0fbdcaa97
26 Nd193f8432e364bbfb382e1a4590b34de
27 Ne6dca9921342424ea1a05fa5f5474044
28 Nebc115208b50451d9c5ebc1fc36b554d
29 Nec4239c4159f48f5ad503628fec65ae7
30 Ned9f1475b501430fb1b1decdd5a734f7
31 Nf9ef38c1cfb8418c8c33db52860e8e25
32 Nfc317d46331a4e65adafa6623149904b
33 anzsrc-for:11
34 anzsrc-for:1117
35 schema:author N1f0f579d32f64bfe92fe217768e56b73
36 schema:citation sg:pub.10.1007/978-3-642-37124-0
37 sg:pub.10.1007/s11239-006-0002-8
38 sg:pub.10.1186/1471-2296-4-3
39 sg:pub.10.1186/1748-5908-7-79
40 https://app.dimensions.ai/details/publication/pub.1083115882
41 https://doi.org/10.1016/j.amjmed.2009.11.025
42 https://doi.org/10.1016/j.jclinepi.2007.11.008
43 https://doi.org/10.1016/s0140-6736(11)61294-4
44 https://doi.org/10.1055/s-0029-1208103
45 https://doi.org/10.1093/europace/eun369
46 https://doi.org/10.1093/europace/eur416
47 https://doi.org/10.1093/europace/eus305
48 https://doi.org/10.1136/bmj.330.7492.644
49 https://doi.org/10.1136/heartjnl-2012-303472
50 https://doi.org/10.1159/000353484
51 https://doi.org/10.1160/th08-06-0361
52 https://doi.org/10.1161/01.cir.0000063575.17904.4e
53 https://doi.org/10.1161/circoutcomes.108.796185
54 https://doi.org/10.1378/chest.11-2288
55 https://doi.org/10.1378/chest.1412s3
56 https://doi.org/10.3238/arztebl.2014.0083
57 schema:datePublished 2014-12
58 schema:datePublishedReg 2014-12-01
59 schema:description BACKGROUND: Oral anticoagulation (OAC) with coumarins and new anticoagulants are highly effective in preventing thromboembolic complications. However, some studies indicate that over- and under-treatment with anticoagulants are fairly common. The aim of this paper is to assess the appropriateness of treatment in patients with a long-term indication for OAC, and to describe the corresponding characteristics of such patients on the basis of screening results from the cluster randomized PICANT trial. METHODS: Randomly selected family practices in the federal state of Hesse, Germany, were visited by study team members. Eligible patients were screened using an anonymous patient list that was generated by the general practitioners' software according to predefined instructions. A documentation sheet was filled in for all screened patients. Eligible patients were classified into 3 categories (1: patients with a long-term indication for OAC and taking anticoagulants, 2: patients with a long-term indication for OAC but not taking anticoagulants, 3: patients without a long-term indication for OAC but taking an anticoagulant on a permanent basis). IBM SPSS Statistics 20 was used for descriptive statistical analysis. RESULTS: We screened 2,036 randomly selected, potentially eligible patients from 52 family practices. 275 patients could not be assigned to one of the 3 categories and were therefore not considered for analysis. The final study sample comprised 1,761 screened patients, 1,641 of whom belonged to category 1, 78 to category 2, and 42 to category 3. INR values were available for 1,504 patients of whom 1,013 presented INR values within their therapeutic ranges. The majority of screened patients had very good compliance, as assessed by the general practitioner. New antithrombotic drugs were prescribed in 6.1% of cases. CONCLUSIONS: The screening results showed that a high proportion of patients were receiving appropriate anticoagulation therapy. The numbers of patients with a long-term indication for OAC therapy that were not receiving oral anticoagulants, and without a long-term indication that were receiving OAC, were considerably lower than expected. Most patients take coumarins, and the quality of OAC control is reasonably high. TRIAL REGISTRATION: Current Controlled Trials ISRCTN41847489.
60 schema:genre research_article
61 schema:inLanguage en
62 schema:isAccessibleForFree true
63 schema:isPartOf N0b507aee20a6465d9226544fda3b7c83
64 Nd3f6029cbf42494fabfad3dd267d1c42
65 sg:journal.1024625
66 schema:name Anticoagulant treatment in German family practices – screening results from a cluster randomized controlled trial
67 schema:pagination 170
68 schema:productId N6f09b38036714093a769e0cedded66f8
69 N706fa9225c8b4da28160e046b6551bec
70 Nb440c4dd557c41718f3f62d345a654aa
71 Nd46e218e766947378c7ee1d3c9da6b3f
72 Nea35201312ee4891be396f4fa339dc42
73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022333908
74 https://doi.org/10.1186/s12875-014-0170-0
75 schema:sdDatePublished 2019-04-11T09:56
76 schema:sdLicense https://scigraph.springernature.com/explorer/license/
77 schema:sdPublisher Nc40c8d7ccd62467688601bc1005eb765
78 schema:url http://link.springer.com/10.1186%2Fs12875-014-0170-0
79 sgo:license sg:explorer/license/
80 sgo:sdDataset articles
81 rdf:type schema:ScholarlyArticle
82 N0b4d91341323479db8932b0d6852632a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Dabigatran
84 rdf:type schema:DefinedTerm
85 N0b507aee20a6465d9226544fda3b7c83 schema:issueNumber 1
86 rdf:type schema:PublicationIssue
87 N10b64e563403498ab942c28aba97db8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name beta-Alanine
89 rdf:type schema:DefinedTerm
90 N1436cdadfe464c1d912626a37c5ef403 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Venous Thromboembolism
92 rdf:type schema:DefinedTerm
93 N17c08c4eecc6457fae99c2b25b6ac16b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Anticoagulants
95 rdf:type schema:DefinedTerm
96 N1f0f579d32f64bfe92fe217768e56b73 rdf:first sg:person.01175462162.29
97 rdf:rest Na31318e6630b4af2ac23b50395458b6a
98 N20e4671bb35c4009af0b7c36fbe28bfd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Mass Screening
100 rdf:type schema:DefinedTerm
101 N292589bd480c45e3807e0dc12ed6332f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Pulmonary Embolism
103 rdf:type schema:DefinedTerm
104 N37e6c2a21f0c4d16b37dd27bd158d5d5 rdf:first sg:person.01120414202.82
105 rdf:rest N40588fd05b0d4a1fb498160ed2bf7191
106 N3d90b0a7de01452fba8cd24cb5cbd17c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Aged, 80 and over
108 rdf:type schema:DefinedTerm
109 N40588fd05b0d4a1fb498160ed2bf7191 rdf:first sg:person.0634417662.64
110 rdf:rest N50b242ef5a3a4354bd96b3b4e3335a71
111 N41963b670253455cade0629891d9837d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name International Normalized Ratio
113 rdf:type schema:DefinedTerm
114 N43b21796472e4ce8b2aeb4a1c4e2abb6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Male
116 rdf:type schema:DefinedTerm
117 N4a986be7feb342968f6f0e0e27aa93e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Pyridones
119 rdf:type schema:DefinedTerm
120 N50b242ef5a3a4354bd96b3b4e3335a71 rdf:first sg:person.0750646262.80
121 rdf:rest Nfcc17332be3c4a47ae788be2f818752c
122 N57158c102e62436185f1fb827075acd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Middle Aged
124 rdf:type schema:DefinedTerm
125 N58c0e3fa92be42c7bf013d1afef31dd5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Family Practice
127 rdf:type schema:DefinedTerm
128 N5a5f2197a75347d0a47440e112534a70 rdf:first sg:person.01370660441.68
129 rdf:rest Nfe3dec05653a4cf0b6a1a56e980a9328
130 N5ccc307a11bd4f0aa48d7a3dcfe09865 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Pyrazoles
132 rdf:type schema:DefinedTerm
133 N5f34b95b5f344e62921715a4de23f5aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Morpholines
135 rdf:type schema:DefinedTerm
136 N60bc47593d66467f8bb8dfbe37aeb012 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Female
138 rdf:type schema:DefinedTerm
139 N66b369d2a5714cc89fe414b5542542e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Administration, Oral
141 rdf:type schema:DefinedTerm
142 N6b965ce2898e4e44b8c1383f48fce77b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Germany
144 rdf:type schema:DefinedTerm
145 N6f09b38036714093a769e0cedded66f8 schema:name nlm_unique_id
146 schema:value 100967792
147 rdf:type schema:PropertyValue
148 N706fa9225c8b4da28160e046b6551bec schema:name doi
149 schema:value 10.1186/s12875-014-0170-0
150 rdf:type schema:PropertyValue
151 N7f005db8f3b0402889a1a07886acfb6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Atrial Fibrillation
153 rdf:type schema:DefinedTerm
154 N891149b8a8454604972517f56bf06c60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Guideline Adherence
156 rdf:type schema:DefinedTerm
157 N8d2bc681b3d14637bc6d493e5b49245d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Rivaroxaban
159 rdf:type schema:DefinedTerm
160 Na27ddd04d57c408aba2889f865b70c26 rdf:first sg:person.0746237506.58
161 rdf:rest N5a5f2197a75347d0a47440e112534a70
162 Na31318e6630b4af2ac23b50395458b6a rdf:first sg:person.0735024423.43
163 rdf:rest N37e6c2a21f0c4d16b37dd27bd158d5d5
164 Nb440c4dd557c41718f3f62d345a654aa schema:name dimensions_id
165 schema:value pub.1022333908
166 rdf:type schema:PropertyValue
167 Nb6d4e3644482444f921f7380f218eccd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Thromboembolism
169 rdf:type schema:DefinedTerm
170 Nba808fef9c344bd0b1142fce9d1d6c4e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Heart Valve Prosthesis
172 rdf:type schema:DefinedTerm
173 Nbb1fd2de61984c58a021c7569b0e81e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Thrombosis
175 rdf:type schema:DefinedTerm
176 Nc2272194ee904822acfa7139a436744a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Coumarins
178 rdf:type schema:DefinedTerm
179 Nc35692ee2cf947afa3d9f4d0fbdcaa97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Practice Guidelines as Topic
181 rdf:type schema:DefinedTerm
182 Nc40c8d7ccd62467688601bc1005eb765 schema:name Springer Nature - SN SciGraph project
183 rdf:type schema:Organization
184 Nd193f8432e364bbfb382e1a4590b34de schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Heart Diseases
186 rdf:type schema:DefinedTerm
187 Nd3f6029cbf42494fabfad3dd267d1c42 schema:volumeNumber 15
188 rdf:type schema:PublicationVolume
189 Nd46e218e766947378c7ee1d3c9da6b3f schema:name pubmed_id
190 schema:value 25344288
191 rdf:type schema:PropertyValue
192 Ne6dca9921342424ea1a05fa5f5474044 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Thiophenes
194 rdf:type schema:DefinedTerm
195 Nea35201312ee4891be396f4fa339dc42 schema:name readcube_id
196 schema:value 6a66cbe855e5c92c1462a416f1684f0a058f49849f0affb644edc2d82c6b87a1
197 rdf:type schema:PropertyValue
198 Nebc115208b50451d9c5ebc1fc36b554d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Humans
200 rdf:type schema:DefinedTerm
201 Nec4239c4159f48f5ad503628fec65ae7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Stroke
203 rdf:type schema:DefinedTerm
204 Ned9f1475b501430fb1b1decdd5a734f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Benzimidazoles
206 rdf:type schema:DefinedTerm
207 Nf9ef38c1cfb8418c8c33db52860e8e25 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
208 schema:name Process Assessment (Health Care)
209 rdf:type schema:DefinedTerm
210 Nfc317d46331a4e65adafa6623149904b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
211 schema:name Aged
212 rdf:type schema:DefinedTerm
213 Nfcc17332be3c4a47ae788be2f818752c rdf:first sg:person.0606534216.00
214 rdf:rest Na27ddd04d57c408aba2889f865b70c26
215 Nfe3dec05653a4cf0b6a1a56e980a9328 rdf:first sg:person.01063613514.45
216 rdf:rest rdf:nil
217 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
218 schema:name Medical and Health Sciences
219 rdf:type schema:DefinedTerm
220 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
221 schema:name Public Health and Health Services
222 rdf:type schema:DefinedTerm
223 sg:journal.1024625 schema:issn 1471-2296
224 schema:name BMC Family Practice
225 rdf:type schema:Periodical
226 sg:person.01063613514.45 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
227 schema:familyName Siebenhofer
228 schema:givenName Andrea
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063613514.45
230 rdf:type schema:Person
231 sg:person.01120414202.82 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
232 schema:familyName Petersen
233 schema:givenName Juliana J
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120414202.82
235 rdf:type schema:Person
236 sg:person.01175462162.29 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
237 schema:familyName Ulrich
238 schema:givenName Lisa-R
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175462162.29
240 rdf:type schema:Person
241 sg:person.01370660441.68 schema:affiliation https://www.grid.ac/institutes/grid.11598.34
242 schema:familyName Berghold
243 schema:givenName Andrea
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01370660441.68
245 rdf:type schema:Person
246 sg:person.0606534216.00 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
247 schema:familyName Kemperdick
248 schema:givenName Birgit
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606534216.00
250 rdf:type schema:Person
251 sg:person.0634417662.64 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
252 schema:familyName Roehl
253 schema:givenName Ina
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634417662.64
255 rdf:type schema:Person
256 sg:person.0735024423.43 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
257 schema:familyName Mergenthal
258 schema:givenName Karola
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735024423.43
260 rdf:type schema:Person
261 sg:person.0746237506.58 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
262 schema:familyName Schulz-Rothe
263 schema:givenName Sylvia
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746237506.58
265 rdf:type schema:Person
266 sg:person.0750646262.80 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
267 schema:familyName Rauck
268 schema:givenName Sandra
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750646262.80
270 rdf:type schema:Person
271 sg:pub.10.1007/978-3-642-37124-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012141922
272 https://doi.org/10.1007/978-3-642-37124-0
273 rdf:type schema:CreativeWork
274 sg:pub.10.1007/s11239-006-0002-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034830965
275 https://doi.org/10.1007/s11239-006-0002-8
276 rdf:type schema:CreativeWork
277 sg:pub.10.1186/1471-2296-4-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047945540
278 https://doi.org/10.1186/1471-2296-4-3
279 rdf:type schema:CreativeWork
280 sg:pub.10.1186/1748-5908-7-79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012756155
281 https://doi.org/10.1186/1748-5908-7-79
282 rdf:type schema:CreativeWork
283 https://app.dimensions.ai/details/publication/pub.1083115882 schema:CreativeWork
284 https://doi.org/10.1016/j.amjmed.2009.11.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014694271
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/j.jclinepi.2007.11.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016528221
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/s0140-6736(11)61294-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029901058
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1055/s-0029-1208103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057181005
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1093/europace/eun369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050885027
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1093/europace/eur416 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012494146
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1093/europace/eus305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030385418
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1136/bmj.330.7492.644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003153124
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1136/heartjnl-2012-303472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028986073
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1159/000353484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037965162
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1160/th08-06-0361 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063291703
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1161/01.cir.0000063575.17904.4e schema:sameAs https://app.dimensions.ai/details/publication/pub.1037218097
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1161/circoutcomes.108.796185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029965959
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1378/chest.11-2288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020246916
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1378/chest.1412s3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044869520
313 rdf:type schema:CreativeWork
314 https://doi.org/10.3238/arztebl.2014.0083 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078879081
315 rdf:type schema:CreativeWork
316 https://www.grid.ac/institutes/grid.11598.34 schema:alternateName Medical University of Graz
317 schema:name Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria
318 rdf:type schema:Organization
319 https://www.grid.ac/institutes/grid.7839.5 schema:alternateName Goethe University Frankfurt
320 schema:name Institute of General Practice, Goethe-University Frankfurt, Frankfurt, Germany
321 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...