iMarmot: an integrative platform for comparative and functional genomics of marmots View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-03-30

AUTHORS

Baoning Liu, Liang Bai, Qingqing Yu, Fang Hu, Jing Wu, Sihai Zhao, Rong Wang, Weirong Wang, Yuanqing Tao, Jianglin Fan, Enqi Liu

ABSTRACT

BackgroundMarmots are large Holarctic rodents with unique biological features, making them potential animal models in various research fields. Due to the rapid accumulation of the genetic data in marmots, a highly integrative database is urgent needed.DescriptioniMarmot is freely available on the web at http://www.marmotdb.org/ and currently contains the biological information of 14 marmots, genomic sequence of 6 marmots, syntenic relationship and orthologs among 3 marmots, and expression profiles of several hibernators and plague hosts. To assist with the genomic and transcriptomic analysis, we also integrated a set of analysis and visualization tools, such as KEGG or GO enrichment analysis, PCA, Blast, Muscle, GeneWise, Lastz, and JBrowse. Particularly, one DEGs (differentially expressed genes) module has been implemented in this database to visualize the gene expression changes in hibernators and plague hosts.ConclusionThis database will provide comprehensive information and analysis platform for researchers interested in understanding the biological features of marmots. More... »

PAGES

266

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12864-020-6697-7

DOI

http://dx.doi.org/10.1186/s12864-020-6697-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1125973562

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32228437


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