Recent genomic heritage in Scotland View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Carmen Amador, Jennifer Huffman, Holly Trochet, Archie Campbell, David Porteous, Generation Scotland, James F Wilson, Nick Hastie, Veronique Vitart, Caroline Hayward, Pau Navarro, Chris S Haley

ABSTRACT

BACKGROUND: The Generation Scotland Scottish Family Health Study (GS:SFHS) includes 23,960 participants from across Scotland with records for many health-related traits and environmental covariates. Genotypes at ~700 K SNPs are currently available for 10,000 participants. The cohort was designed as a resource for genetic and health related research and the study of complex traits. In this study we developed a suite of analyses to disentangle the genomic differentiation within GS:SFHS individuals to describe and optimise the sample and methods for future analyses. RESULTS: We combined the genotypic information of GS:SFHS with 1092 individuals from the 1000 Genomes project and estimated their genomic relationships. Then, we performed Principal Component Analyses of the resulting relationships to investigate the genomic origin of different groups. We characterised two groups of individuals: those with a few sparse rare markers in the genome, and those with several large rare haplotypes which might represent relatively recent exogenous ancestors. We identified some individuals with likely Italian ancestry and a group with some potential African/Asian ancestry. An analysis of homozygosity in the GS:SFHS sample revealed a very similar pattern to other European populations. We also identified an individual carrying a chromosome 1 uniparental disomy. We found evidence of local geographic stratification within the population having impact on the genomic structure. CONCLUSIONS: These findings illuminate the history of the Scottish population and have implications for further analyses such as the study of the contributions of common and rare variants to trait heritabilities and the evaluation of genomic and phenotypic prediction of disease. More... »

PAGES

437

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12864-015-1605-2

DOI

http://dx.doi.org/10.1186/s12864-015-1605-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030543495

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26048416


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "African Continental Ancestry Group", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Asian Continental Ancestry Group", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "European Continental Ancestry Group", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phylogeography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Population Dynamics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Principal Component Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quantitative Trait, Heritable", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Scotland", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amador", 
        "givenName": "Carmen", 
        "id": "sg:person.0613307227.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613307227.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huffman", 
        "givenName": "Jennifer", 
        "id": "sg:person.0612256763.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612256763.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Trochet", 
        "givenName": "Holly", 
        "id": "sg:person.0727535627.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727535627.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Campbell", 
        "givenName": "Archie", 
        "id": "sg:person.0775651027.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775651027.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Porteous", 
        "givenName": "David", 
        "id": "sg:person.012230156744.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012230156744.42"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Generation Scotland", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "Centre for Population Health Sciences, University of Edinburgh, EH8 9AG, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wilson", 
        "givenName": "James F", 
        "id": "sg:person.01060172311.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060172311.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hastie", 
        "givenName": "Nick", 
        "id": "sg:person.012226301424.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012226301424.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vitart", 
        "givenName": "Veronique", 
        "id": "sg:person.01276752315.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276752315.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hayward", 
        "givenName": "Caroline", 
        "id": "sg:person.01317433110.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317433110.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Navarro", 
        "givenName": "Pau", 
        "id": "sg:person.01345065515.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345065515.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Edinburgh", 
          "id": "https://www.grid.ac/institutes/grid.4305.2", 
          "name": [
            "MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK", 
            "Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG, Edinburgh, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Haley", 
        "givenName": "Chris S", 
        "id": "sg:person.07574021277.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07574021277.15"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/hmg/ddn268", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000051176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature05911", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004556449", 
          "https://doi.org/10.1038/nature05911"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004749772", 
          "https://doi.org/10.1038/nrg1123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004749772", 
          "https://doi.org/10.1038/nrg1123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature07331", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005519278", 
          "https://doi.org/10.1038/nature07331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000288706", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006140976"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature07566", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006342445", 
          "https://doi.org/10.1038/nature07566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.126037.111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008825044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajhg.2010.11.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009497006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/bts571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009674763"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1069424", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010139737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010608717", 
          "https://doi.org/10.1038/nature09534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010608717", 
          "https://doi.org/10.1038/nature09534"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.094052.109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010760027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011014033", 
          "https://doi.org/10.1038/ng1333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011014033", 
          "https://doi.org/10.1038/ng1333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014662746", 
          "https://doi.org/10.1038/ng1508"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014662746", 
          "https://doi.org/10.1038/ng1508"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.608", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015057090", 
          "https://doi.org/10.1038/ng.608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.608", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015057090", 
          "https://doi.org/10.1038/ng.608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajhg.2008.08.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016924755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/519795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019061180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ije/dys084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019789173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2350-7-74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030074679", 
          "https://doi.org/10.1186/1471-2350-7-74"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/btm108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031184798"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1847", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031429813", 
          "https://doi.org/10.1038/ng1847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1847", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031429813", 
          "https://doi.org/10.1038/ng1847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035486054", 
          "https://doi.org/10.1038/nrg865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035486054", 
          "https://doi.org/10.1038/nrg865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ejhg.2010.87", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038231952", 
          "https://doi.org/10.1038/ejhg.2010.87"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ejhg.2010.87", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038231952", 
          "https://doi.org/10.1038/ejhg.2010.87"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.1970304", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038640119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0013996", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039955304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gepi.20434", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043825550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gepi.20434", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043825550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-13-28", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045225234", 
          "https://doi.org/10.1186/1471-2105-13-28"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3125610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062592548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3325/cmj.2009.50.7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071145602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1214/lnms/1215091145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1086780659"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-12", 
    "datePublishedReg": "2015-12-01", 
    "description": "BACKGROUND: The Generation Scotland Scottish Family Health Study (GS:SFHS) includes 23,960 participants from across Scotland with records for many health-related traits and environmental covariates. Genotypes at ~700 K SNPs are currently available for 10,000 participants. The cohort was designed as a resource for genetic and health related research and the study of complex traits. In this study we developed a suite of analyses to disentangle the genomic differentiation within GS:SFHS individuals to describe and optimise the sample and methods for future analyses.\nRESULTS: We combined the genotypic information of GS:SFHS with 1092 individuals from the 1000 Genomes project and estimated their genomic relationships. Then, we performed Principal Component Analyses of the resulting relationships to investigate the genomic origin of different groups. We characterised two groups of individuals: those with a few sparse rare markers in the genome, and those with several large rare haplotypes which might represent relatively recent exogenous ancestors. We identified some individuals with likely Italian ancestry and a group with some potential African/Asian ancestry. An analysis of homozygosity in the GS:SFHS sample revealed a very similar pattern to other European populations. We also identified an individual carrying a chromosome 1 uniparental disomy. We found evidence of local geographic stratification within the population having impact on the genomic structure.\nCONCLUSIONS: These findings illuminate the history of the Scottish population and have implications for further analyses such as the study of the contributions of common and rare variants to trait heritabilities and the evaluation of genomic and phenotypic prediction of disease.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/s12864-015-1605-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5147354", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2786906", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5148567", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2777851", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1023790", 
        "issn": [
          "1471-2164"
        ], 
        "name": "BMC Genomics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "16"
      }
    ], 
    "name": "Recent genomic heritage in Scotland", 
    "pagination": "437", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "91813da74f8cb316704b70ab06ba0e65b22bde2f7babdd4652805d1a88923693"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26048416"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100965258"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12864-015-1605-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1030543495"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12864-015-1605-2", 
      "https://app.dimensions.ai/details/publication/pub.1030543495"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:03", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89824_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2Fs12864-015-1605-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12864-015-1605-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12864-015-1605-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12864-015-1605-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12864-015-1605-2'


 

This table displays all metadata directly associated to this object as RDF triples.

315 TRIPLES      21 PREDICATES      74 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12864-015-1605-2 schema:about N15c791d8473d4b95a0c403e107bf5548
2 N1e2ed841e81c466f8cf8c80b9a14e1cb
3 N1ef18b8da00d4b64b56d30bd6318ac2d
4 N37080fc753d94923a561e6516f3c44cc
5 N4a6b8ad90f234d0a85f726bc7a606c3b
6 N6f477911138f42f9bf43ef310ffb2edf
7 N7f9cce49443d4f82994a855b85e3d347
8 Nb5e71d4c0d33443aad4a271b56756024
9 Nb8dafd25d47d4c2ea940af3520e36415
10 Nc1c79438e67b451183062eb767d6dd09
11 Ne0651bcdd4064f569c43ce31ad1e6b2d
12 Ne4f41cf9f5dd47a68c788bc8df3c4846
13 Ne6ab995518154231abc493d7cf75c2bf
14 Neff82ff4802747c1b28503e9b2911c9e
15 Nf09ca90094834252b1cd5d09604dff21
16 anzsrc-for:06
17 anzsrc-for:0604
18 schema:author N409067473d864166998736dfdb321d2c
19 schema:citation sg:pub.10.1038/ejhg.2010.87
20 sg:pub.10.1038/nature05911
21 sg:pub.10.1038/nature07331
22 sg:pub.10.1038/nature07566
23 sg:pub.10.1038/nature09534
24 sg:pub.10.1038/ng.608
25 sg:pub.10.1038/ng1333
26 sg:pub.10.1038/ng1508
27 sg:pub.10.1038/ng1847
28 sg:pub.10.1038/nrg1123
29 sg:pub.10.1038/nrg865
30 sg:pub.10.1186/1471-2105-13-28
31 sg:pub.10.1186/1471-2350-7-74
32 https://doi.org/10.1002/gepi.20434
33 https://doi.org/10.1016/j.ajhg.2008.08.007
34 https://doi.org/10.1016/j.ajhg.2010.11.011
35 https://doi.org/10.1086/519795
36 https://doi.org/10.1093/bioinformatics/btm108
37 https://doi.org/10.1093/bioinformatics/bts571
38 https://doi.org/10.1093/hmg/ddn268
39 https://doi.org/10.1093/ije/dys084
40 https://doi.org/10.1101/gr.094052.109
41 https://doi.org/10.1101/gr.126037.111
42 https://doi.org/10.1101/gr.1970304
43 https://doi.org/10.1126/science.1069424
44 https://doi.org/10.1126/science.3125610
45 https://doi.org/10.1159/000288706
46 https://doi.org/10.1214/lnms/1215091145
47 https://doi.org/10.1371/journal.pone.0013996
48 https://doi.org/10.3325/cmj.2009.50.7
49 schema:datePublished 2015-12
50 schema:datePublishedReg 2015-12-01
51 schema:description BACKGROUND: The Generation Scotland Scottish Family Health Study (GS:SFHS) includes 23,960 participants from across Scotland with records for many health-related traits and environmental covariates. Genotypes at ~700 K SNPs are currently available for 10,000 participants. The cohort was designed as a resource for genetic and health related research and the study of complex traits. In this study we developed a suite of analyses to disentangle the genomic differentiation within GS:SFHS individuals to describe and optimise the sample and methods for future analyses. RESULTS: We combined the genotypic information of GS:SFHS with 1092 individuals from the 1000 Genomes project and estimated their genomic relationships. Then, we performed Principal Component Analyses of the resulting relationships to investigate the genomic origin of different groups. We characterised two groups of individuals: those with a few sparse rare markers in the genome, and those with several large rare haplotypes which might represent relatively recent exogenous ancestors. We identified some individuals with likely Italian ancestry and a group with some potential African/Asian ancestry. An analysis of homozygosity in the GS:SFHS sample revealed a very similar pattern to other European populations. We also identified an individual carrying a chromosome 1 uniparental disomy. We found evidence of local geographic stratification within the population having impact on the genomic structure. CONCLUSIONS: These findings illuminate the history of the Scottish population and have implications for further analyses such as the study of the contributions of common and rare variants to trait heritabilities and the evaluation of genomic and phenotypic prediction of disease.
52 schema:genre research_article
53 schema:inLanguage en
54 schema:isAccessibleForFree true
55 schema:isPartOf N392e0536fa424a569a0d70d2e57bd215
56 N9ced61eff5e64c248beeb1544b98c914
57 sg:journal.1023790
58 schema:name Recent genomic heritage in Scotland
59 schema:pagination 437
60 schema:productId N670724e4de8f4010a71fb6ab0c0c40e5
61 N8dfca1c9fbd54f9d9c9e9ac4ab6c1330
62 N9aab3a0a1da04d618226d998aaa4cbcb
63 Nf17b05128be3466089147cdf1be01f39
64 Nf96f8143410443348ec41814e4a7ed27
65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030543495
66 https://doi.org/10.1186/s12864-015-1605-2
67 schema:sdDatePublished 2019-04-11T10:03
68 schema:sdLicense https://scigraph.springernature.com/explorer/license/
69 schema:sdPublisher N1e87149c03ef440d8e04c63003b2c053
70 schema:url http://link.springer.com/10.1186%2Fs12864-015-1605-2
71 sgo:license sg:explorer/license/
72 sgo:sdDataset articles
73 rdf:type schema:ScholarlyArticle
74 N11759b248bf4440bb5aa773358ecd8e3 rdf:first N9ac9eb928e874f23bbcd0cbd4a1d4b2a
75 rdf:rest N6d962ec6816c404cbb14e2d494e1f1d5
76 N15c791d8473d4b95a0c403e107bf5548 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name African Continental Ancestry Group
78 rdf:type schema:DefinedTerm
79 N1e2ed841e81c466f8cf8c80b9a14e1cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Genotype
81 rdf:type schema:DefinedTerm
82 N1e87149c03ef440d8e04c63003b2c053 schema:name Springer Nature - SN SciGraph project
83 rdf:type schema:Organization
84 N1ef18b8da00d4b64b56d30bd6318ac2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Female
86 rdf:type schema:DefinedTerm
87 N37080fc753d94923a561e6516f3c44cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Quantitative Trait, Heritable
89 rdf:type schema:DefinedTerm
90 N392e0536fa424a569a0d70d2e57bd215 schema:issueNumber 1
91 rdf:type schema:PublicationIssue
92 N3f6374eb1a704afeb04a4883073050de rdf:first sg:person.0775651027.78
93 rdf:rest N657dccff47d446b1bb60c183ab2596c6
94 N409067473d864166998736dfdb321d2c rdf:first sg:person.0613307227.89
95 rdf:rest N4228fce1ee514f11af54bd2b70faaaa1
96 N418f3a642d4e4004a34efc112e314a58 rdf:first sg:person.01345065515.28
97 rdf:rest Na713eafb474d46a1b6dcc2bed25a3a92
98 N4228fce1ee514f11af54bd2b70faaaa1 rdf:first sg:person.0612256763.55
99 rdf:rest Nb16fc0e3d77842519edd2ee1727f41f7
100 N4a6b8ad90f234d0a85f726bc7a606c3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Humans
102 rdf:type schema:DefinedTerm
103 N657dccff47d446b1bb60c183ab2596c6 rdf:first sg:person.012230156744.42
104 rdf:rest N11759b248bf4440bb5aa773358ecd8e3
105 N670724e4de8f4010a71fb6ab0c0c40e5 schema:name doi
106 schema:value 10.1186/s12864-015-1605-2
107 rdf:type schema:PropertyValue
108 N6d962ec6816c404cbb14e2d494e1f1d5 rdf:first sg:person.01060172311.14
109 rdf:rest Ne34d46e4b7e04d58856fe67091b73cf3
110 N6f477911138f42f9bf43ef310ffb2edf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Male
112 rdf:type schema:DefinedTerm
113 N7f9cce49443d4f82994a855b85e3d347 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Scotland
115 rdf:type schema:DefinedTerm
116 N8dfca1c9fbd54f9d9c9e9ac4ab6c1330 schema:name pubmed_id
117 schema:value 26048416
118 rdf:type schema:PropertyValue
119 N9aab3a0a1da04d618226d998aaa4cbcb schema:name dimensions_id
120 schema:value pub.1030543495
121 rdf:type schema:PropertyValue
122 N9ac9eb928e874f23bbcd0cbd4a1d4b2a schema:familyName Generation Scotland
123 rdf:type schema:Person
124 N9ced61eff5e64c248beeb1544b98c914 schema:volumeNumber 16
125 rdf:type schema:PublicationVolume
126 Na713eafb474d46a1b6dcc2bed25a3a92 rdf:first sg:person.07574021277.15
127 rdf:rest rdf:nil
128 Nb16fc0e3d77842519edd2ee1727f41f7 rdf:first sg:person.0727535627.16
129 rdf:rest N3f6374eb1a704afeb04a4883073050de
130 Nb5e71d4c0d33443aad4a271b56756024 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Phylogeography
132 rdf:type schema:DefinedTerm
133 Nb8dafd25d47d4c2ea940af3520e36415 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Models, Genetic
135 rdf:type schema:DefinedTerm
136 Nc1c79438e67b451183062eb767d6dd09 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Principal Component Analysis
138 rdf:type schema:DefinedTerm
139 Ne0651bcdd4064f569c43ce31ad1e6b2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Asian Continental Ancestry Group
141 rdf:type schema:DefinedTerm
142 Ne34d46e4b7e04d58856fe67091b73cf3 rdf:first sg:person.012226301424.49
143 rdf:rest Ne6b6f14aee954b089e72f78e78c0c0da
144 Ne4f41cf9f5dd47a68c788bc8df3c4846 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Polymorphism, Single Nucleotide
146 rdf:type schema:DefinedTerm
147 Ne6ab995518154231abc493d7cf75c2bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name European Continental Ancestry Group
149 rdf:type schema:DefinedTerm
150 Ne6b6f14aee954b089e72f78e78c0c0da rdf:first sg:person.01276752315.18
151 rdf:rest Nf8550d6e593446c2901b01d5cba07776
152 Neff82ff4802747c1b28503e9b2911c9e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Genome, Human
154 rdf:type schema:DefinedTerm
155 Nf09ca90094834252b1cd5d09604dff21 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Population Dynamics
157 rdf:type schema:DefinedTerm
158 Nf17b05128be3466089147cdf1be01f39 schema:name readcube_id
159 schema:value 91813da74f8cb316704b70ab06ba0e65b22bde2f7babdd4652805d1a88923693
160 rdf:type schema:PropertyValue
161 Nf8550d6e593446c2901b01d5cba07776 rdf:first sg:person.01317433110.75
162 rdf:rest N418f3a642d4e4004a34efc112e314a58
163 Nf96f8143410443348ec41814e4a7ed27 schema:name nlm_unique_id
164 schema:value 100965258
165 rdf:type schema:PropertyValue
166 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
167 schema:name Biological Sciences
168 rdf:type schema:DefinedTerm
169 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
170 schema:name Genetics
171 rdf:type schema:DefinedTerm
172 sg:grant.2777851 http://pending.schema.org/fundedItem sg:pub.10.1186/s12864-015-1605-2
173 rdf:type schema:MonetaryGrant
174 sg:grant.2786906 http://pending.schema.org/fundedItem sg:pub.10.1186/s12864-015-1605-2
175 rdf:type schema:MonetaryGrant
176 sg:grant.5147354 http://pending.schema.org/fundedItem sg:pub.10.1186/s12864-015-1605-2
177 rdf:type schema:MonetaryGrant
178 sg:grant.5148567 http://pending.schema.org/fundedItem sg:pub.10.1186/s12864-015-1605-2
179 rdf:type schema:MonetaryGrant
180 sg:journal.1023790 schema:issn 1471-2164
181 schema:name BMC Genomics
182 rdf:type schema:Periodical
183 sg:person.01060172311.14 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
184 schema:familyName Wilson
185 schema:givenName James F
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060172311.14
187 rdf:type schema:Person
188 sg:person.012226301424.49 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
189 schema:familyName Hastie
190 schema:givenName Nick
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012226301424.49
192 rdf:type schema:Person
193 sg:person.012230156744.42 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
194 schema:familyName Porteous
195 schema:givenName David
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012230156744.42
197 rdf:type schema:Person
198 sg:person.01276752315.18 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
199 schema:familyName Vitart
200 schema:givenName Veronique
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276752315.18
202 rdf:type schema:Person
203 sg:person.01317433110.75 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
204 schema:familyName Hayward
205 schema:givenName Caroline
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317433110.75
207 rdf:type schema:Person
208 sg:person.01345065515.28 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
209 schema:familyName Navarro
210 schema:givenName Pau
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345065515.28
212 rdf:type schema:Person
213 sg:person.0612256763.55 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
214 schema:familyName Huffman
215 schema:givenName Jennifer
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612256763.55
217 rdf:type schema:Person
218 sg:person.0613307227.89 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
219 schema:familyName Amador
220 schema:givenName Carmen
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613307227.89
222 rdf:type schema:Person
223 sg:person.0727535627.16 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
224 schema:familyName Trochet
225 schema:givenName Holly
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727535627.16
227 rdf:type schema:Person
228 sg:person.07574021277.15 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
229 schema:familyName Haley
230 schema:givenName Chris S
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07574021277.15
232 rdf:type schema:Person
233 sg:person.0775651027.78 schema:affiliation https://www.grid.ac/institutes/grid.4305.2
234 schema:familyName Campbell
235 schema:givenName Archie
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0775651027.78
237 rdf:type schema:Person
238 sg:pub.10.1038/ejhg.2010.87 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038231952
239 https://doi.org/10.1038/ejhg.2010.87
240 rdf:type schema:CreativeWork
241 sg:pub.10.1038/nature05911 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004556449
242 https://doi.org/10.1038/nature05911
243 rdf:type schema:CreativeWork
244 sg:pub.10.1038/nature07331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005519278
245 https://doi.org/10.1038/nature07331
246 rdf:type schema:CreativeWork
247 sg:pub.10.1038/nature07566 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006342445
248 https://doi.org/10.1038/nature07566
249 rdf:type schema:CreativeWork
250 sg:pub.10.1038/nature09534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010608717
251 https://doi.org/10.1038/nature09534
252 rdf:type schema:CreativeWork
253 sg:pub.10.1038/ng.608 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015057090
254 https://doi.org/10.1038/ng.608
255 rdf:type schema:CreativeWork
256 sg:pub.10.1038/ng1333 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011014033
257 https://doi.org/10.1038/ng1333
258 rdf:type schema:CreativeWork
259 sg:pub.10.1038/ng1508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014662746
260 https://doi.org/10.1038/ng1508
261 rdf:type schema:CreativeWork
262 sg:pub.10.1038/ng1847 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031429813
263 https://doi.org/10.1038/ng1847
264 rdf:type schema:CreativeWork
265 sg:pub.10.1038/nrg1123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004749772
266 https://doi.org/10.1038/nrg1123
267 rdf:type schema:CreativeWork
268 sg:pub.10.1038/nrg865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035486054
269 https://doi.org/10.1038/nrg865
270 rdf:type schema:CreativeWork
271 sg:pub.10.1186/1471-2105-13-28 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045225234
272 https://doi.org/10.1186/1471-2105-13-28
273 rdf:type schema:CreativeWork
274 sg:pub.10.1186/1471-2350-7-74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030074679
275 https://doi.org/10.1186/1471-2350-7-74
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1002/gepi.20434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043825550
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/j.ajhg.2008.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016924755
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/j.ajhg.2010.11.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009497006
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1093/bioinformatics/btm108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031184798
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1093/bioinformatics/bts571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009674763
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1093/hmg/ddn268 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000051176
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1093/ije/dys084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019789173
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1101/gr.094052.109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010760027
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1101/gr.126037.111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008825044
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1101/gr.1970304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038640119
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1126/science.1069424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010139737
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1126/science.3125610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062592548
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1159/000288706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006140976
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1214/lnms/1215091145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086780659
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1371/journal.pone.0013996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039955304
308 rdf:type schema:CreativeWork
309 https://doi.org/10.3325/cmj.2009.50.7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071145602
310 rdf:type schema:CreativeWork
311 https://www.grid.ac/institutes/grid.4305.2 schema:alternateName University of Edinburgh
312 schema:name Centre for Population Health Sciences, University of Edinburgh, EH8 9AG, Edinburgh, UK
313 MRC IGMM, University of Edinburgh, EH4 2XU, Edinburgh, UK
314 Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG, Edinburgh, UK
315 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...