Cancer characterization and diagnosis with SERS-encoded particles View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-12

AUTHORS

Luca Guerrini, Nicolas Pazos-Perez, Eduardo Garcia-Rico, Ramon Alvarez-Puebla

ABSTRACT

Early diagnosis, monitoring and treatment selection of cancer represent major challenges in medicine. The definition of the complex clinical and molecular landscape of cancer requires the combination of multiple techniques and the investigation of multiple targets. As a result, diagnosis is normally lengthy, expensive and, in many cases, cannot be performed recursively. In recent years, optical biosensors, especially those based on the unique properties of plasmonic nanostructures, have emerged as one of the most exciting tools in nanomedicine, capable of overcoming key limitations of classical techniques. In this review, we specifically focus our attention on the latest advances in optical biosensors exploiting surface-enhanced Raman scattering encoded particles for the characterization of tumor single cells (molecular biology) and tissues (immunohistochemistry and guided surgery), as well as their application in guided surgery or even in bioimaging of living organisms. More... »

PAGES

5

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12645-017-0031-3

    DOI

    http://dx.doi.org/10.1186/s12645-017-0031-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1092271896


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