Early resolution of subretinal fluid without high-dose corticosteroids in a pregnant patient with Vogt-Koyanagi-Harada disease: a case report View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Keijiro Sugita, Kyoichi Mizumoto, Nahoko Kato, Masahiro Zako

ABSTRACT

BACKGROUND: At present, there is no standard of treatment using systemic high-dose corticosteroids in cases of pregnant women with Vogt-Koyanagi-Harada (VKH) disease. Although high-dose systemic corticosteroid treatment is often used for VKH disease during pregnancy, it also poses a risk to the fetus. FINDINGS: A 29-year-old woman in the 34th week of pregnancy experienced bilateral metamorphopsia. She had been receiving 5 mg of prednisolone daily for the past 8 years as treatment for rheumatoid arthritis. In order to prevent progression of bilateral serous retinal detachment caused by VKH disease, we recommended the use of high-dose systemic corticosteroids but the patient refused. Thus, we administered only topical ophthalmic betamethasone for mild anterior uveitis. Surprisingly, however, the bilateral bullous retinal detachment healed in just 19 days after the onset of symptoms. A healthy baby was born 1 month later, and sunset glow fundus was subsequently observed without any recurrence of uveitis. CONCLUSIONS: We report a case in which bilateral subretinal fluid caused by VKH disease in a young woman during late pregnancy resolved without high-dose corticosteroid treatment. Pregnancy may have had a beneficial effect on uveitis activity caused by VKH disease. To our knowledge, this report describes the shortest healing period for bilateral bullous retinal detachment in a pregnant woman with VKH disease. More... »

PAGES

20

References to SciGraph publications

  • 2011-06. Headache in late pregnancy: a symptom for Vogt–Koyanagi–Harada disease in ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • 2007-06. Vogt–Koyanagi–Harada disease diagnostic criteria in INTERNATIONAL OPHTHALMOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s12348-015-0050-3

    DOI

    http://dx.doi.org/10.1186/s12348-015-0050-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1003682385

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26140057


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Aichi Medical University", 
              "id": "https://www.grid.ac/institutes/grid.411234.1", 
              "name": [
                "Department of Ophthalmology, Aichi Medical University, 480-1195, Nagakute, Aichi, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sugita", 
            "givenName": "Keijiro", 
            "id": "sg:person.0651565375.92", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651565375.92"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aichi Medical University", 
              "id": "https://www.grid.ac/institutes/grid.411234.1", 
              "name": [
                "Department of Ophthalmology, Aichi Medical University, 480-1195, Nagakute, Aichi, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mizumoto", 
            "givenName": "Kyoichi", 
            "id": "sg:person.01226757252.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226757252.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aichi Medical University", 
              "id": "https://www.grid.ac/institutes/grid.411234.1", 
              "name": [
                "Department of Ophthalmology, Aichi Medical University, 480-1195, Nagakute, Aichi, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kato", 
            "givenName": "Nahoko", 
            "id": "sg:person.0766013775.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766013775.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aichi Medical University", 
              "id": "https://www.grid.ac/institutes/grid.411234.1", 
              "name": [
                "Department of Ophthalmology, Aichi Medical University, 480-1195, Nagakute, Aichi, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zako", 
            "givenName": "Masahiro", 
            "id": "sg:person.01323246576.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323246576.76"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1136/bjo.79.1.94", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001236642"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9394(03)00110-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003428777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9394(03)00110-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003428777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/pmj.77.905.157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005148912"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/pmj.77.905.157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005148912"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0021-5155(00)00357-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017813225"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1034/j.1600-0420.2000.078001093.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021413920"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1517/14656566.5.3.571", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035733510"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00404-010-1748-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038319234", 
              "https://doi.org/10.1007/s00404-010-1748-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9394(14)75078-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040752733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3129/i09-011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044003927"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10792-006-9021-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051318511", 
              "https://doi.org/10.1007/s10792-006-9021-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077588643", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078651405", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082362751", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2015-12", 
        "datePublishedReg": "2015-12-01", 
        "description": "BACKGROUND: At present, there is no standard of treatment using systemic high-dose corticosteroids in cases of pregnant women with Vogt-Koyanagi-Harada (VKH) disease. Although high-dose systemic corticosteroid treatment is often used for VKH disease during pregnancy, it also poses a risk to the fetus.\nFINDINGS: A 29-year-old woman in the 34th week of pregnancy experienced bilateral metamorphopsia. She had been receiving 5\u00a0mg of prednisolone daily for the past 8\u00a0years as treatment for rheumatoid arthritis. In order to prevent progression of bilateral serous retinal detachment caused by VKH disease, we recommended the use of high-dose systemic corticosteroids but the patient refused. Thus, we administered only topical ophthalmic betamethasone for mild anterior uveitis. Surprisingly, however, the bilateral bullous retinal detachment healed in just 19\u00a0days after the onset of symptoms. A healthy baby was born 1\u00a0month later, and sunset glow fundus was subsequently observed without any recurrence of uveitis.\nCONCLUSIONS: We report a case in which bilateral subretinal fluid caused by VKH disease in a young woman during late pregnancy resolved without high-dose corticosteroid treatment. Pregnancy may have had a beneficial effect on uveitis activity caused by VKH disease. To our knowledge, this report describes the shortest healing period for bilateral bullous retinal detachment in a pregnant woman with VKH disease.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1186/s12348-015-0050-3", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1044713", 
            "issn": [
              "1869-5760"
            ], 
            "name": "Journal of Ophthalmic Inflammation and Infection", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "1", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "5"
          }
        ], 
        "name": "Early resolution of subretinal fluid without high-dose corticosteroids in a pregnant patient with Vogt-Koyanagi-Harada disease: a case report", 
        "pagination": "20", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "118a9718dee1f819fc9426aa428f066c4e00df8c15bc050cccfbfe724fec85eb"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "26140057"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "101553216"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1186/s12348-015-0050-3"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1003682385"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1186/s12348-015-0050-3", 
          "https://app.dimensions.ai/details/publication/pub.1003682385"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T10:03", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89824_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1186%2Fs12348-015-0050-3"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12348-015-0050-3'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12348-015-0050-3'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12348-015-0050-3'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12348-015-0050-3'


     

    This table displays all metadata directly associated to this object as RDF triples.

    127 TRIPLES      21 PREDICATES      42 URIs      21 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1186/s12348-015-0050-3 schema:about anzsrc-for:11
    2 anzsrc-for:1103
    3 schema:author N29585b5b317b4d0ea87b2269838505c9
    4 schema:citation sg:pub.10.1007/s00404-010-1748-y
    5 sg:pub.10.1007/s10792-006-9021-x
    6 https://app.dimensions.ai/details/publication/pub.1077588643
    7 https://app.dimensions.ai/details/publication/pub.1078651405
    8 https://app.dimensions.ai/details/publication/pub.1082362751
    9 https://doi.org/10.1016/s0002-9394(03)00110-7
    10 https://doi.org/10.1016/s0002-9394(14)75078-0
    11 https://doi.org/10.1016/s0021-5155(00)00357-9
    12 https://doi.org/10.1034/j.1600-0420.2000.078001093.x
    13 https://doi.org/10.1136/bjo.79.1.94
    14 https://doi.org/10.1136/pmj.77.905.157
    15 https://doi.org/10.1517/14656566.5.3.571
    16 https://doi.org/10.3129/i09-011
    17 schema:datePublished 2015-12
    18 schema:datePublishedReg 2015-12-01
    19 schema:description BACKGROUND: At present, there is no standard of treatment using systemic high-dose corticosteroids in cases of pregnant women with Vogt-Koyanagi-Harada (VKH) disease. Although high-dose systemic corticosteroid treatment is often used for VKH disease during pregnancy, it also poses a risk to the fetus. FINDINGS: A 29-year-old woman in the 34th week of pregnancy experienced bilateral metamorphopsia. She had been receiving 5 mg of prednisolone daily for the past 8 years as treatment for rheumatoid arthritis. In order to prevent progression of bilateral serous retinal detachment caused by VKH disease, we recommended the use of high-dose systemic corticosteroids but the patient refused. Thus, we administered only topical ophthalmic betamethasone for mild anterior uveitis. Surprisingly, however, the bilateral bullous retinal detachment healed in just 19 days after the onset of symptoms. A healthy baby was born 1 month later, and sunset glow fundus was subsequently observed without any recurrence of uveitis. CONCLUSIONS: We report a case in which bilateral subretinal fluid caused by VKH disease in a young woman during late pregnancy resolved without high-dose corticosteroid treatment. Pregnancy may have had a beneficial effect on uveitis activity caused by VKH disease. To our knowledge, this report describes the shortest healing period for bilateral bullous retinal detachment in a pregnant woman with VKH disease.
    20 schema:genre research_article
    21 schema:inLanguage en
    22 schema:isAccessibleForFree true
    23 schema:isPartOf N6f5822d6f5a54dd8a39066e3734eaa53
    24 N877b381ebea84ae097da2c0780170168
    25 sg:journal.1044713
    26 schema:name Early resolution of subretinal fluid without high-dose corticosteroids in a pregnant patient with Vogt-Koyanagi-Harada disease: a case report
    27 schema:pagination 20
    28 schema:productId N14b20f6a49b34b58b6dfa3a33a7ff7dd
    29 N1b6bdb44ecc64e4eb9a806f2f2e569aa
    30 N529026293c7b416d9f6ddc268f6ad0ad
    31 N82295750785747c29caeb8905d2bb10b
    32 Nd9010386499a40dc8de9876798fdaf53
    33 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003682385
    34 https://doi.org/10.1186/s12348-015-0050-3
    35 schema:sdDatePublished 2019-04-11T10:03
    36 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    37 schema:sdPublisher N767bb179a62f452281245c07d8271387
    38 schema:url http://link.springer.com/10.1186%2Fs12348-015-0050-3
    39 sgo:license sg:explorer/license/
    40 sgo:sdDataset articles
    41 rdf:type schema:ScholarlyArticle
    42 N082d50720420419c8c833c97b2456c52 rdf:first sg:person.01226757252.24
    43 rdf:rest Nce225bd28bc048148d7857736c8d11ac
    44 N14b20f6a49b34b58b6dfa3a33a7ff7dd schema:name pubmed_id
    45 schema:value 26140057
    46 rdf:type schema:PropertyValue
    47 N1b6bdb44ecc64e4eb9a806f2f2e569aa schema:name nlm_unique_id
    48 schema:value 101553216
    49 rdf:type schema:PropertyValue
    50 N29585b5b317b4d0ea87b2269838505c9 rdf:first sg:person.0651565375.92
    51 rdf:rest N082d50720420419c8c833c97b2456c52
    52 N3933ff558d724ff9aeb122aabb4b49e9 rdf:first sg:person.01323246576.76
    53 rdf:rest rdf:nil
    54 N529026293c7b416d9f6ddc268f6ad0ad schema:name readcube_id
    55 schema:value 118a9718dee1f819fc9426aa428f066c4e00df8c15bc050cccfbfe724fec85eb
    56 rdf:type schema:PropertyValue
    57 N6f5822d6f5a54dd8a39066e3734eaa53 schema:volumeNumber 5
    58 rdf:type schema:PublicationVolume
    59 N767bb179a62f452281245c07d8271387 schema:name Springer Nature - SN SciGraph project
    60 rdf:type schema:Organization
    61 N82295750785747c29caeb8905d2bb10b schema:name dimensions_id
    62 schema:value pub.1003682385
    63 rdf:type schema:PropertyValue
    64 N877b381ebea84ae097da2c0780170168 schema:issueNumber 1
    65 rdf:type schema:PublicationIssue
    66 Nce225bd28bc048148d7857736c8d11ac rdf:first sg:person.0766013775.10
    67 rdf:rest N3933ff558d724ff9aeb122aabb4b49e9
    68 Nd9010386499a40dc8de9876798fdaf53 schema:name doi
    69 schema:value 10.1186/s12348-015-0050-3
    70 rdf:type schema:PropertyValue
    71 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    72 schema:name Medical and Health Sciences
    73 rdf:type schema:DefinedTerm
    74 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    75 schema:name Clinical Sciences
    76 rdf:type schema:DefinedTerm
    77 sg:journal.1044713 schema:issn 1869-5760
    78 schema:name Journal of Ophthalmic Inflammation and Infection
    79 rdf:type schema:Periodical
    80 sg:person.01226757252.24 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
    81 schema:familyName Mizumoto
    82 schema:givenName Kyoichi
    83 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226757252.24
    84 rdf:type schema:Person
    85 sg:person.01323246576.76 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
    86 schema:familyName Zako
    87 schema:givenName Masahiro
    88 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01323246576.76
    89 rdf:type schema:Person
    90 sg:person.0651565375.92 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
    91 schema:familyName Sugita
    92 schema:givenName Keijiro
    93 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651565375.92
    94 rdf:type schema:Person
    95 sg:person.0766013775.10 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
    96 schema:familyName Kato
    97 schema:givenName Nahoko
    98 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766013775.10
    99 rdf:type schema:Person
    100 sg:pub.10.1007/s00404-010-1748-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1038319234
    101 https://doi.org/10.1007/s00404-010-1748-y
    102 rdf:type schema:CreativeWork
    103 sg:pub.10.1007/s10792-006-9021-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051318511
    104 https://doi.org/10.1007/s10792-006-9021-x
    105 rdf:type schema:CreativeWork
    106 https://app.dimensions.ai/details/publication/pub.1077588643 schema:CreativeWork
    107 https://app.dimensions.ai/details/publication/pub.1078651405 schema:CreativeWork
    108 https://app.dimensions.ai/details/publication/pub.1082362751 schema:CreativeWork
    109 https://doi.org/10.1016/s0002-9394(03)00110-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003428777
    110 rdf:type schema:CreativeWork
    111 https://doi.org/10.1016/s0002-9394(14)75078-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040752733
    112 rdf:type schema:CreativeWork
    113 https://doi.org/10.1016/s0021-5155(00)00357-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017813225
    114 rdf:type schema:CreativeWork
    115 https://doi.org/10.1034/j.1600-0420.2000.078001093.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021413920
    116 rdf:type schema:CreativeWork
    117 https://doi.org/10.1136/bjo.79.1.94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001236642
    118 rdf:type schema:CreativeWork
    119 https://doi.org/10.1136/pmj.77.905.157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005148912
    120 rdf:type schema:CreativeWork
    121 https://doi.org/10.1517/14656566.5.3.571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035733510
    122 rdf:type schema:CreativeWork
    123 https://doi.org/10.3129/i09-011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044003927
    124 rdf:type schema:CreativeWork
    125 https://www.grid.ac/institutes/grid.411234.1 schema:alternateName Aichi Medical University
    126 schema:name Department of Ophthalmology, Aichi Medical University, 480-1195, Nagakute, Aichi, Japan
    127 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...