Determinants of polyunsaturated fatty acid concentrations in erythrocytes of pregnant Japanese women from a birth cohort study: study protocol and ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-04-04

AUTHORS

Shoji Saito, Terue Kawabata, Nozomi Tatsuta, Fumiko Kimura, Teruo Miyazawa, Satoshi Mizuno, Hidekazu Nishigori, Takahiro Arima, Yasuo Kagawa, Kouichi Yoshimasu, Kanami Tsuno, Yuki Ito, Michihiro Kamijima, Kunihiko Nakai, Nobuo Yaegashi,

ABSTRACT

BACKGROUND: N-3 polyunsaturated fatty acids (n-3 PUFA) may have multiple beneficial effects on the outcome of pregnancy, maternal health and child development. The present study introduced the protocol of a birth cohort study to examine the beneficial effects of n-3 PUFA status in pregnant Japanese women as an adjunct study of the Japan Environment and Children's Study (JECS). METHODS: The JECS participants in the coastal areas of Miyagi Prefecture were further invited to participate in this adjunct study, and 1,878 pregnant women were enrolled prior to delivery. Their n-3 PUFA status was evaluated with fatty acid profiles in erythrocytes of maternal blood collected from 1,623 mothers at 24-30 weeks of gestation and cord blood from 1,505 deliveries. RESULTS: The baseline results, including comprehensive data on the fatty acid status and determinants affecting the PUFA status, were analyzed. In stepwise multivariate analyses, the cord blood docosahexaenoic acid (DHA) level was found to be significantly influenced by the DHA level in maternal blood, the child's sex, and the gestational period. The maternal DHA level was influenced by fish intake, maternal age, and the prepregnancy body mass index. While cord blood eicosapentaenoic acid (EPA) was influenced by maternal EPA, fish intake, and season at birth, additional factors such as maternal education, household income, and smoking habits affected the maternal EPA content. CONCLUSION: Further studies are warranted to clarify the nutritional impacts of n-3 PUFA in pregnant Japanese women of the cohort study. More... »

PAGES

22

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s12199-017-0636-5

DOI

http://dx.doi.org/10.1186/s12199-017-0636-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084612310

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29165130


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Erythrocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fatty Acids, Unsaturated", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fetal Blood", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Japan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reference Values", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Surveys and Questionnaires", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Obstetrics and Gynecology, Yamagata Prefectural Central Hospital, Aoyagi 1800, Yamagata, 990-2292 Japan", 
          "id": "http://www.grid.ac/institutes/grid.417323.0", 
          "name": [
            "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan", 
            "Department of Obstetrics and Gynecology, Yamagata Prefectural Central Hospital, Aoyagi 1800, Yamagata, 990-2292 Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saito", 
        "givenName": "Shoji", 
        "id": "sg:person.011714776307.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011714776307.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Nutrition, Kagawa Nutrition University, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.411981.4", 
          "name": [
            "Faculty of Nutrition, Kagawa Nutrition University, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kawabata", 
        "givenName": "Terue", 
        "id": "sg:person.0640451506.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640451506.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tatsuta", 
        "givenName": "Nozomi", 
        "id": "sg:person.01200045755.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200045755.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Human Health and Nutrition, Shokei Gakuin University Graduate School, Natori, Japan", 
          "id": "http://www.grid.ac/institutes/grid.444293.c", 
          "name": [
            "Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Sciences, Tohoku University, Sendai, Japan", 
            "Department of Human Health and Nutrition, Shokei Gakuin University Graduate School, Natori, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kimura", 
        "givenName": "Fumiko", 
        "id": "sg:person.01075262746.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075262746.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Human Health and Nutrition, Shokei Gakuin University Graduate School, Natori, Japan", 
            "New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyazawa", 
        "givenName": "Teruo", 
        "id": "sg:person.01143376146.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143376146.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mizuno", 
        "givenName": "Satoshi", 
        "id": "sg:person.01241056465.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241056465.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishigori", 
        "givenName": "Hidekazu", 
        "id": "sg:person.01167766763.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167766763.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Informative Genetics, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Informative Genetics, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arima", 
        "givenName": "Takahiro", 
        "id": "sg:person.01150330275.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150330275.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kagawa", 
        "givenName": "Yasuo", 
        "id": "sg:person.01315742406.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315742406.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Hygiene, School of Medicine, Wakayama Medical University, Wakayama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412857.d", 
          "name": [
            "Department of Hygiene, School of Medicine, Wakayama Medical University, Wakayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshimasu", 
        "givenName": "Kouichi", 
        "id": "sg:person.0751057623.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751057623.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Hygiene, School of Medicine, Wakayama Medical University, Wakayama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.412857.d", 
          "name": [
            "Department of Hygiene, School of Medicine, Wakayama Medical University, Wakayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsuno", 
        "givenName": "Kanami", 
        "id": "sg:person.0744536443.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744536443.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan", 
          "id": "http://www.grid.ac/institutes/grid.260433.0", 
          "name": [
            "Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ito", 
        "givenName": "Yuki", 
        "id": "sg:person.01047321017.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047321017.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan", 
          "id": "http://www.grid.ac/institutes/grid.260433.0", 
          "name": [
            "Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kamijima", 
        "givenName": "Michihiro", 
        "id": "sg:person.01346371060.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346371060.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakai", 
        "givenName": "Kunihiko", 
        "id": "sg:person.01044504653.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044504653.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan", 
          "id": "http://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yaegashi", 
        "givenName": "Nobuo", 
        "id": "sg:person.01025052736.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025052736.40"
        ], 
        "type": "Person"
      }, 
      {}
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1471-2458-14-25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049930448", 
          "https://doi.org/10.1186/1471-2458-14-25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.ejcn.1600444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005085574", 
          "https://doi.org/10.1038/sj.ejcn.1600444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10654-015-0106-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003711498", 
          "https://doi.org/10.1007/s10654-015-0106-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ejcn.2014.219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053517801", 
          "https://doi.org/10.1038/ejcn.2014.219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/tp.2016.2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047708941", 
          "https://doi.org/10.1038/tp.2016.2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12944-016-0220-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000829401", 
          "https://doi.org/10.1186/s12944-016-0220-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11745-006-1392-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011747335", 
          "https://doi.org/10.1007/s11745-006-1392-2"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-04-04", 
    "datePublishedReg": "2017-04-04", 
    "description": "BACKGROUND: N-3 polyunsaturated fatty acids (n-3 PUFA) may have multiple beneficial effects on the outcome of pregnancy, maternal health and child development. The present study introduced the protocol of a birth cohort study to examine the beneficial effects of n-3 PUFA status in pregnant Japanese women as an adjunct study of the Japan Environment and Children's Study (JECS).\nMETHODS: The JECS participants in the coastal areas of Miyagi Prefecture were further invited to participate in this adjunct study, and 1,878 pregnant women were enrolled prior to delivery. Their n-3 PUFA status was evaluated with fatty acid profiles in erythrocytes of maternal blood collected from 1,623 mothers at 24-30 weeks of gestation and cord blood from 1,505 deliveries.\nRESULTS: The baseline results, including comprehensive data on the fatty acid status and determinants affecting the PUFA status, were analyzed. In stepwise multivariate analyses, the cord blood docosahexaenoic acid (DHA) level was found to be significantly influenced by the DHA level in maternal blood, the child's sex, and the gestational period. The maternal DHA level was influenced by fish intake, maternal age, and the prepregnancy body mass index. While cord blood eicosapentaenoic acid (EPA) was influenced by maternal EPA, fish intake, and season at birth, additional factors such as maternal education, household income, and smoking habits affected the maternal EPA content.\nCONCLUSION: Further studies are warranted to clarify the nutritional impacts of n-3 PUFA in pregnant Japanese women of the cohort study.", 
    "genre": "article", 
    "id": "sg:pub.10.1186/s12199-017-0636-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6138649", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6150448", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.9340131", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5912780", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1115673", 
        "issn": [
          "1342-078X", 
          "1347-4715"
        ], 
        "name": "Environmental Health and Preventive Medicine", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "22"
      }
    ], 
    "keywords": [
      "pregnant Japanese women", 
      "birth cohort study", 
      "PUFA status", 
      "cohort study", 
      "Japanese women", 
      "adjunct study", 
      "Japan Environment", 
      "fish intake", 
      "cord blood", 
      "maternal blood", 
      "eicosapentaenoic acid", 
      "DHA levels", 
      "prepregnancy body mass index", 
      "beneficial effects", 
      "maternal DHA levels", 
      "blood eicosapentaenoic acid", 
      "maternal eicosapentaenoic acid", 
      "outcome of pregnancy", 
      "Children's Study", 
      "weeks of gestation", 
      "body mass index", 
      "fatty acid status", 
      "stepwise multivariate analysis", 
      "multiple beneficial effects", 
      "smoking habits", 
      "mass index", 
      "pregnant women", 
      "maternal health", 
      "maternal age", 
      "study protocol", 
      "fatty acid concentrations", 
      "acid status", 
      "gestational period", 
      "baseline findings", 
      "multivariate analysis", 
      "maternal education", 
      "blood", 
      "acid levels", 
      "women", 
      "child sex", 
      "Further studies", 
      "intake", 
      "nutritional impact", 
      "fatty acid profile", 
      "present study", 
      "fatty acids", 
      "status", 
      "sex", 
      "erythrocytes", 
      "acid profile", 
      "household income", 
      "baseline results", 
      "delivery", 
      "additional factors", 
      "child development", 
      "pregnancy", 
      "gestation", 
      "study", 
      "acid concentration", 
      "levels", 
      "EPA content", 
      "weeks", 
      "determinants", 
      "PUFA", 
      "birth", 
      "outcomes", 
      "age", 
      "mothers", 
      "comprehensive data", 
      "health", 
      "protocol", 
      "effect", 
      "participants", 
      "acid", 
      "findings", 
      "habits", 
      "index", 
      "Miyagi Prefecture", 
      "period", 
      "factors", 
      "profile", 
      "concentration", 
      "data", 
      "development", 
      "education", 
      "impact", 
      "income", 
      "analysis", 
      "area", 
      "results", 
      "Prefecture", 
      "content", 
      "environment", 
      "season", 
      "coastal areas", 
      "JECS participants", 
      "cord blood eicosapentaenoic acid", 
      "maternal EPA content"
    ], 
    "name": "Determinants of polyunsaturated fatty acid concentrations in erythrocytes of pregnant Japanese women from a birth cohort study: study protocol and baseline findings of an adjunct study of the Japan environment & Children\u2019s study", 
    "pagination": "22", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1084612310"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/s12199-017-0636-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29165130"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/s12199-017-0636-5", 
      "https://app.dimensions.ai/details/publication/pub.1084612310"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:45", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_733.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1186/s12199-017-0636-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/s12199-017-0636-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/s12199-017-0636-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/s12199-017-0636-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/s12199-017-0636-5'


 

This table displays all metadata directly associated to this object as RDF triples.

364 TRIPLES      22 PREDICATES      142 URIs      127 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/s12199-017-0636-5 schema:about N1ad3bff7670b48ee86badf33e6eda97c
2 N1fe73828743a496b81958a24b8e3f867
3 N2576e59baca04933811fb69a9ea430c4
4 N29fef2d0c2404cf485d4be15f9f20b9d
5 N40fa745f055b48fd9bc3779fa26c2a05
6 N66ce635d3f3f47dc88c0091ad2152646
7 N7d2025747ecf4ba4b5673c8f8bc1a66d
8 Nc4e72b66a2874af19d08e8f6dcbb7ec1
9 Ncb20b854cccf4f22a5a4d4b87a3f483d
10 Ndcf744e3f25e40eba1513acea1a503ac
11 Ndd55df4f1f164236b6394ed2bb497b82
12 anzsrc-for:11
13 anzsrc-for:1114
14 schema:author N8000952557bb418cb187705494861522
15 schema:citation sg:pub.10.1007/s10654-015-0106-6
16 sg:pub.10.1007/s11745-006-1392-2
17 sg:pub.10.1038/ejcn.2014.219
18 sg:pub.10.1038/sj.ejcn.1600444
19 sg:pub.10.1038/tp.2016.2
20 sg:pub.10.1186/1471-2458-14-25
21 sg:pub.10.1186/s12944-016-0220-9
22 schema:datePublished 2017-04-04
23 schema:datePublishedReg 2017-04-04
24 schema:description BACKGROUND: N-3 polyunsaturated fatty acids (n-3 PUFA) may have multiple beneficial effects on the outcome of pregnancy, maternal health and child development. The present study introduced the protocol of a birth cohort study to examine the beneficial effects of n-3 PUFA status in pregnant Japanese women as an adjunct study of the Japan Environment and Children's Study (JECS). METHODS: The JECS participants in the coastal areas of Miyagi Prefecture were further invited to participate in this adjunct study, and 1,878 pregnant women were enrolled prior to delivery. Their n-3 PUFA status was evaluated with fatty acid profiles in erythrocytes of maternal blood collected from 1,623 mothers at 24-30 weeks of gestation and cord blood from 1,505 deliveries. RESULTS: The baseline results, including comprehensive data on the fatty acid status and determinants affecting the PUFA status, were analyzed. In stepwise multivariate analyses, the cord blood docosahexaenoic acid (DHA) level was found to be significantly influenced by the DHA level in maternal blood, the child's sex, and the gestational period. The maternal DHA level was influenced by fish intake, maternal age, and the prepregnancy body mass index. While cord blood eicosapentaenoic acid (EPA) was influenced by maternal EPA, fish intake, and season at birth, additional factors such as maternal education, household income, and smoking habits affected the maternal EPA content. CONCLUSION: Further studies are warranted to clarify the nutritional impacts of n-3 PUFA in pregnant Japanese women of the cohort study.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree true
28 schema:isPartOf Nd1a07a8f2c4c443c8a27046ad2ddb388
29 Nda6d20a2323f46609d78eea72458ccf2
30 sg:journal.1115673
31 schema:keywords Children's Study
32 DHA levels
33 EPA content
34 Further studies
35 JECS participants
36 Japan Environment
37 Japanese women
38 Miyagi Prefecture
39 PUFA
40 PUFA status
41 Prefecture
42 acid
43 acid concentration
44 acid levels
45 acid profile
46 acid status
47 additional factors
48 adjunct study
49 age
50 analysis
51 area
52 baseline findings
53 baseline results
54 beneficial effects
55 birth
56 birth cohort study
57 blood
58 blood eicosapentaenoic acid
59 body mass index
60 child development
61 child sex
62 coastal areas
63 cohort study
64 comprehensive data
65 concentration
66 content
67 cord blood
68 cord blood eicosapentaenoic acid
69 data
70 delivery
71 determinants
72 development
73 education
74 effect
75 eicosapentaenoic acid
76 environment
77 erythrocytes
78 factors
79 fatty acid concentrations
80 fatty acid profile
81 fatty acid status
82 fatty acids
83 findings
84 fish intake
85 gestation
86 gestational period
87 habits
88 health
89 household income
90 impact
91 income
92 index
93 intake
94 levels
95 mass index
96 maternal DHA levels
97 maternal EPA content
98 maternal age
99 maternal blood
100 maternal education
101 maternal eicosapentaenoic acid
102 maternal health
103 mothers
104 multiple beneficial effects
105 multivariate analysis
106 nutritional impact
107 outcome of pregnancy
108 outcomes
109 participants
110 period
111 pregnancy
112 pregnant Japanese women
113 pregnant women
114 prepregnancy body mass index
115 present study
116 profile
117 protocol
118 results
119 season
120 sex
121 smoking habits
122 status
123 stepwise multivariate analysis
124 study
125 study protocol
126 weeks
127 weeks of gestation
128 women
129 schema:name Determinants of polyunsaturated fatty acid concentrations in erythrocytes of pregnant Japanese women from a birth cohort study: study protocol and baseline findings of an adjunct study of the Japan environment & Children’s study
130 schema:pagination 22
131 schema:productId N5175dbb152a74db0a1fcc57fbc95f268
132 N5240ea8ab68b46389792b717bc744874
133 Nd3c6aca456ac4f38a921301f2ed979bc
134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084612310
135 https://doi.org/10.1186/s12199-017-0636-5
136 schema:sdDatePublished 2022-01-01T18:45
137 schema:sdLicense https://scigraph.springernature.com/explorer/license/
138 schema:sdPublisher N40650ae4b7b8477c93ca1ef4bdc7440d
139 schema:url https://doi.org/10.1186/s12199-017-0636-5
140 sgo:license sg:explorer/license/
141 sgo:sdDataset articles
142 rdf:type schema:ScholarlyArticle
143 N0abf729ac0a34fd7a54969168ca2dc51 rdf:first sg:person.01241056465.17
144 rdf:rest N0e19f57149d74a6b9e9402bee1c1668b
145 N0e19f57149d74a6b9e9402bee1c1668b rdf:first sg:person.01167766763.35
146 rdf:rest Nb19020edb81741298c12a748b0ce2246
147 N0eb784dd5c504cc48a9667fea34c2367 rdf:first sg:person.0751057623.18
148 rdf:rest N527cc91147c1476b9511d2e0e67a3948
149 N1ad3bff7670b48ee86badf33e6eda97c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Humans
151 rdf:type schema:DefinedTerm
152 N1fe73828743a496b81958a24b8e3f867 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Reference Values
154 rdf:type schema:DefinedTerm
155 N2576e59baca04933811fb69a9ea430c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Young Adult
157 rdf:type schema:DefinedTerm
158 N28ebd378bb2b45a3be80cff4c178b1f0 rdf:first sg:person.0640451506.47
159 rdf:rest N4cb27a5777e84b70b84d70b8d7a4c8c4
160 N29fef2d0c2404cf485d4be15f9f20b9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Fetal Blood
162 rdf:type schema:DefinedTerm
163 N2ce38b2318b541cd802af665b980b06f rdf:first sg:person.01075262746.22
164 rdf:rest N8a4f8def8c0549928cb317e1d79c8a4e
165 N3e72b6d5b0894ecc90476f9e959ecddd rdf:first sg:person.01047321017.35
166 rdf:rest N73acdcdfecaf4699b75cbb8c25179e4f
167 N40650ae4b7b8477c93ca1ef4bdc7440d schema:name Springer Nature - SN SciGraph project
168 rdf:type schema:Organization
169 N40fa745f055b48fd9bc3779fa26c2a05 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Surveys and Questionnaires
171 rdf:type schema:DefinedTerm
172 N4c1894cabcc1454fafd2509941f3c28c rdf:first Nf849d37b813c44f8bf34be0e37e7dd2c
173 rdf:rest rdf:nil
174 N4cb27a5777e84b70b84d70b8d7a4c8c4 rdf:first sg:person.01200045755.45
175 rdf:rest N2ce38b2318b541cd802af665b980b06f
176 N5175dbb152a74db0a1fcc57fbc95f268 schema:name pubmed_id
177 schema:value 29165130
178 rdf:type schema:PropertyValue
179 N5240ea8ab68b46389792b717bc744874 schema:name dimensions_id
180 schema:value pub.1084612310
181 rdf:type schema:PropertyValue
182 N527cc91147c1476b9511d2e0e67a3948 rdf:first sg:person.0744536443.58
183 rdf:rest N3e72b6d5b0894ecc90476f9e959ecddd
184 N66ce635d3f3f47dc88c0091ad2152646 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Erythrocytes
186 rdf:type schema:DefinedTerm
187 N73acdcdfecaf4699b75cbb8c25179e4f rdf:first sg:person.01346371060.05
188 rdf:rest N8d2180999d6e403fbd96e12c78da8ad0
189 N7d2025747ecf4ba4b5673c8f8bc1a66d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Adult
191 rdf:type schema:DefinedTerm
192 N8000952557bb418cb187705494861522 rdf:first sg:person.011714776307.52
193 rdf:rest N28ebd378bb2b45a3be80cff4c178b1f0
194 N8a4f8def8c0549928cb317e1d79c8a4e rdf:first sg:person.01143376146.31
195 rdf:rest N0abf729ac0a34fd7a54969168ca2dc51
196 N8d2180999d6e403fbd96e12c78da8ad0 rdf:first sg:person.01044504653.19
197 rdf:rest N94bf968197bf45d79d98b113ad9ba38a
198 N94bf968197bf45d79d98b113ad9ba38a rdf:first sg:person.01025052736.40
199 rdf:rest N4c1894cabcc1454fafd2509941f3c28c
200 Nb19020edb81741298c12a748b0ce2246 rdf:first sg:person.01150330275.86
201 rdf:rest Ncc9a373819764bafad26b744cd3680bd
202 Nc4e72b66a2874af19d08e8f6dcbb7ec1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Japan
204 rdf:type schema:DefinedTerm
205 Ncb20b854cccf4f22a5a4d4b87a3f483d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Female
207 rdf:type schema:DefinedTerm
208 Ncc9a373819764bafad26b744cd3680bd rdf:first sg:person.01315742406.84
209 rdf:rest N0eb784dd5c504cc48a9667fea34c2367
210 Nd1a07a8f2c4c443c8a27046ad2ddb388 schema:issueNumber 1
211 rdf:type schema:PublicationIssue
212 Nd3c6aca456ac4f38a921301f2ed979bc schema:name doi
213 schema:value 10.1186/s12199-017-0636-5
214 rdf:type schema:PropertyValue
215 Nda6d20a2323f46609d78eea72458ccf2 schema:volumeNumber 22
216 rdf:type schema:PublicationVolume
217 Ndcf744e3f25e40eba1513acea1a503ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
218 schema:name Fatty Acids, Unsaturated
219 rdf:type schema:DefinedTerm
220 Ndd55df4f1f164236b6394ed2bb497b82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
221 schema:name Cohort Studies
222 rdf:type schema:DefinedTerm
223 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
224 schema:name Medical and Health Sciences
225 rdf:type schema:DefinedTerm
226 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
227 schema:name Paediatrics and Reproductive Medicine
228 rdf:type schema:DefinedTerm
229 sg:grant.5912780 http://pending.schema.org/fundedItem sg:pub.10.1186/s12199-017-0636-5
230 rdf:type schema:MonetaryGrant
231 sg:grant.6138649 http://pending.schema.org/fundedItem sg:pub.10.1186/s12199-017-0636-5
232 rdf:type schema:MonetaryGrant
233 sg:grant.6150448 http://pending.schema.org/fundedItem sg:pub.10.1186/s12199-017-0636-5
234 rdf:type schema:MonetaryGrant
235 sg:grant.9340131 http://pending.schema.org/fundedItem sg:pub.10.1186/s12199-017-0636-5
236 rdf:type schema:MonetaryGrant
237 sg:journal.1115673 schema:issn 1342-078X
238 1347-4715
239 schema:name Environmental Health and Preventive Medicine
240 schema:publisher Springer Nature
241 rdf:type schema:Periodical
242 sg:person.01025052736.40 schema:affiliation grid-institutes:grid.69566.3a
243 schema:familyName Yaegashi
244 schema:givenName Nobuo
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025052736.40
246 rdf:type schema:Person
247 sg:person.01044504653.19 schema:affiliation grid-institutes:grid.69566.3a
248 schema:familyName Nakai
249 schema:givenName Kunihiko
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044504653.19
251 rdf:type schema:Person
252 sg:person.01047321017.35 schema:affiliation grid-institutes:grid.260433.0
253 schema:familyName Ito
254 schema:givenName Yuki
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047321017.35
256 rdf:type schema:Person
257 sg:person.01075262746.22 schema:affiliation grid-institutes:grid.444293.c
258 schema:familyName Kimura
259 schema:givenName Fumiko
260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075262746.22
261 rdf:type schema:Person
262 sg:person.01143376146.31 schema:affiliation grid-institutes:grid.69566.3a
263 schema:familyName Miyazawa
264 schema:givenName Teruo
265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143376146.31
266 rdf:type schema:Person
267 sg:person.01150330275.86 schema:affiliation grid-institutes:grid.69566.3a
268 schema:familyName Arima
269 schema:givenName Takahiro
270 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01150330275.86
271 rdf:type schema:Person
272 sg:person.01167766763.35 schema:affiliation grid-institutes:grid.69566.3a
273 schema:familyName Nishigori
274 schema:givenName Hidekazu
275 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167766763.35
276 rdf:type schema:Person
277 sg:person.011714776307.52 schema:affiliation grid-institutes:grid.417323.0
278 schema:familyName Saito
279 schema:givenName Shoji
280 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011714776307.52
281 rdf:type schema:Person
282 sg:person.01200045755.45 schema:affiliation grid-institutes:grid.69566.3a
283 schema:familyName Tatsuta
284 schema:givenName Nozomi
285 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01200045755.45
286 rdf:type schema:Person
287 sg:person.01241056465.17 schema:affiliation grid-institutes:grid.69566.3a
288 schema:familyName Mizuno
289 schema:givenName Satoshi
290 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241056465.17
291 rdf:type schema:Person
292 sg:person.01315742406.84 schema:affiliation grid-institutes:grid.69566.3a
293 schema:familyName Kagawa
294 schema:givenName Yasuo
295 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315742406.84
296 rdf:type schema:Person
297 sg:person.01346371060.05 schema:affiliation grid-institutes:grid.260433.0
298 schema:familyName Kamijima
299 schema:givenName Michihiro
300 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346371060.05
301 rdf:type schema:Person
302 sg:person.0640451506.47 schema:affiliation grid-institutes:grid.411981.4
303 schema:familyName Kawabata
304 schema:givenName Terue
305 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0640451506.47
306 rdf:type schema:Person
307 sg:person.0744536443.58 schema:affiliation grid-institutes:grid.412857.d
308 schema:familyName Tsuno
309 schema:givenName Kanami
310 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744536443.58
311 rdf:type schema:Person
312 sg:person.0751057623.18 schema:affiliation grid-institutes:grid.412857.d
313 schema:familyName Yoshimasu
314 schema:givenName Kouichi
315 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751057623.18
316 rdf:type schema:Person
317 sg:pub.10.1007/s10654-015-0106-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003711498
318 https://doi.org/10.1007/s10654-015-0106-6
319 rdf:type schema:CreativeWork
320 sg:pub.10.1007/s11745-006-1392-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011747335
321 https://doi.org/10.1007/s11745-006-1392-2
322 rdf:type schema:CreativeWork
323 sg:pub.10.1038/ejcn.2014.219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053517801
324 https://doi.org/10.1038/ejcn.2014.219
325 rdf:type schema:CreativeWork
326 sg:pub.10.1038/sj.ejcn.1600444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005085574
327 https://doi.org/10.1038/sj.ejcn.1600444
328 rdf:type schema:CreativeWork
329 sg:pub.10.1038/tp.2016.2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047708941
330 https://doi.org/10.1038/tp.2016.2
331 rdf:type schema:CreativeWork
332 sg:pub.10.1186/1471-2458-14-25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049930448
333 https://doi.org/10.1186/1471-2458-14-25
334 rdf:type schema:CreativeWork
335 sg:pub.10.1186/s12944-016-0220-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000829401
336 https://doi.org/10.1186/s12944-016-0220-9
337 rdf:type schema:CreativeWork
338 grid-institutes:grid.260433.0 schema:alternateName Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
339 schema:name Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
340 rdf:type schema:Organization
341 grid-institutes:grid.411981.4 schema:alternateName Faculty of Nutrition, Kagawa Nutrition University, Saitama, Japan
342 schema:name Faculty of Nutrition, Kagawa Nutrition University, Saitama, Japan
343 rdf:type schema:Organization
344 grid-institutes:grid.412857.d schema:alternateName Department of Hygiene, School of Medicine, Wakayama Medical University, Wakayama, Japan
345 schema:name Department of Hygiene, School of Medicine, Wakayama Medical University, Wakayama, Japan
346 rdf:type schema:Organization
347 grid-institutes:grid.417323.0 schema:alternateName Department of Obstetrics and Gynecology, Yamagata Prefectural Central Hospital, Aoyagi 1800, Yamagata, 990-2292 Japan
348 schema:name Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan
349 Department of Obstetrics and Gynecology, Yamagata Prefectural Central Hospital, Aoyagi 1800, Yamagata, 990-2292 Japan
350 rdf:type schema:Organization
351 grid-institutes:grid.444293.c schema:alternateName Department of Human Health and Nutrition, Shokei Gakuin University Graduate School, Natori, Japan
352 schema:name Department of Human Health and Nutrition, Shokei Gakuin University Graduate School, Natori, Japan
353 Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Sciences, Tohoku University, Sendai, Japan
354 rdf:type schema:Organization
355 grid-institutes:grid.69566.3a schema:alternateName Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
356 Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan
357 Department of Informative Genetics, Tohoku University Graduate School of Medicine, Sendai, Japan
358 New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan
359 schema:name Department of Development and Environmental Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
360 Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Japan
361 Department of Human Health and Nutrition, Shokei Gakuin University Graduate School, Natori, Japan
362 Department of Informative Genetics, Tohoku University Graduate School of Medicine, Sendai, Japan
363 New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan
364 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...