Some patients (and some of us) respond better to some biological therapies: the as yet unsolved conundrum View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-12

AUTHORS

Isabel Andia, Nicola Maffulli

ABSTRACT

Very often, treatment for many common musculoskeletal conditions is only palliative, or involves surgery with major shortcomings. Biological interventions-in particular, platelet-rich plasma (PRP) therapies-may well provide more effective treatments, but their actual efficacy is under scrutiny. PRP is biologically unique to each individual depending on endogenous and exogenous factors, including, but not limited to, demographic factors (i.e. age), immune status (i.e. microbiota), metabolic diseases and concomitant medications. All these potential modifiers of the ultimate effects of PRP have been poorly explored, and their relationship with efficacy has not been established. More... »

PAGES

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Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/s10195-018-0505-z

DOI

http://dx.doi.org/10.1186/s10195-018-0505-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105537620

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30128775


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