Serologic features of cohorts with variable genetic risk for systemic lupus erythematosus View Full Text


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Article Info

DATE

2018-12

AUTHORS

Jyotsna Bhattacharya, Karalyn Pappas, Bahtiyar Toz, Cynthia Aranow, Meggan Mackay, Peter K. Gregersen, Ogobara Doumbo, Abdel Kader Traore, Martin L. Lesser, Maureen McMahon, Tammy Utset, Earl Silverman, Deborah Levy, William J. McCune, Meenakshi Jolly, Daniel Wallace, Michael Weisman, Juanita Romero-Diaz, Betty Diamond

ABSTRACT

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease with genetic, hormonal, and environmental influences. In Western Europe and North America, individuals of West African descent have a 3-4 fold greater incidence of SLE than Caucasians. Paradoxically, West Africans in sub-Saharan Africa appear to have a low incidence of SLE, and some studies suggest a milder disease with less nephritis. In this study, we analyzed sera from African American female SLE patients and four other cohorts, one with SLE and others with varying degrees of risk for SLE in order to identify serologic factors that might correlate with risk of or protection against SLE. METHODS: Our cohorts included West African women with previous malaria infection assumed to be protected from development of SLE, clinically unaffected sisters of SLE patients with high risk of developing SLE, healthy African American women with intermediate risk, healthy Caucasian women with low risk of developing SLE, and women with a diagnosis of SLE. We developed a lupus risk index (LRI) based on titers of IgM and IgG anti-double stranded DNA antibodies and levels of C1q. RESULTS: The risk index was highest in SLE patients; second highest in unaffected sisters of SLE patients; third highest in healthy African-American women and lowest in healthy Caucasian women and malaria-exposed West African women. CONCLUSION: This risk index may be useful in early interventions to prevent SLE. In addition, it suggests new therapeutic approaches for the treatment of SLE. More... »

PAGES

24

References to SciGraph publications

  • 2003-03. Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population in HUMAN GENETICS
  • 2005-10. Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts in NATURE MEDICINE
  • 2000-02. Risk for rheumatic disease in relation to ethnicity and admixture in ARTHRITIS RESEARCH & THERAPY
  • 2015-12. Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus in ARTHRITIS RESEARCH & THERAPY
  • 2006-07. C1q complement component and -antibodies reflect SLE activity and kidney involvement in CLINICAL RHEUMATOLOGY
  • 1970-04. Suppression of Autoimmune Disease in NZB and (NZB×NZW)F1 Hybrid Mice by Infection with Malaria in NATURE
  • 2006-11. Toll-like receptors in systemic autoimmune disease in NATURE REVIEWS IMMUNOLOGY
  • 2007-10. Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production in GENES & IMMUNITY
  • 2014-04. Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE in NATURE REVIEWS RHEUMATOLOGY
  • 2014-07. Natural IgM: Beneficial Autoantibodies for the Control of Inflammatory and Autoimmune Disease in JOURNAL OF CLINICAL IMMUNOLOGY
  • 2014-01. C1q-Mediated Repression of Human Monocytes Is Regulated by Leukocyte-Associated Ig-Like Receptor 1 (LAIR-1) in MOLECULAR MEDICINE
  • 2015-12. Fundamental role of C1q in autoimmunity and inflammation in IMMUNOLOGIC RESEARCH
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/s10020-018-0019-4

    DOI

    http://dx.doi.org/10.1186/s10020-018-0019-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1104308229

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30134810


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