Genetic susceptibility to psoriasis: an emerging picture View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-12

AUTHORS

Rhodri Ll Smith, Richard B Warren, Christopher EM Griffiths, Jane Worthington

ABSTRACT

Psoriasis is recognized as a complex disease for which multiple genetic and non-genetic factors influence susceptibility. The major susceptibility locus resides in the MHC class I region and, until relatively recently, evidence for non-MHC loci was inconsistent. Like many common diseases, knowledge of the genetic basis of this condition has been advanced dramatically in recent times with the advent of genome-wide association studies using single nucleotide polymorphisms. Here, we give an overview of current knowledge of genetic risk factors for psoriasis and consider emerging studies that may further add to our understanding of the genetic basis of the disease. More... »

PAGES

72

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    http://scigraph.springernature.com/pub.10.1186/gm72

    DOI

    http://dx.doi.org/10.1186/gm72

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1021315025

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19638187


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