Kraken: ultrafast metagenomic sequence classification using exact alignments View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-03

AUTHORS

Derrick E Wood, Steven L Salzberg

ABSTRACT

Kraken is an ultrafast and highly accurate program for assigning taxonomic labels to metagenomic DNA sequences. Previous programs designed for this task have been relatively slow and computationally expensive, forcing researchers to use faster abundance estimation programs, which only classify small subsets of metagenomic data. Using exact alignment of k-mers, Kraken achieves classification accuracy comparable to the fastest BLAST program. In its fastest mode, Kraken classifies 100 base pair reads at a rate of over 4.1 million reads per minute, 909 times faster than Megablast and 11 times faster than the abundance estimation program MetaPhlAn. Kraken is available at http://ccb.jhu.edu/software/kraken/. More... »

PAGES

r46

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/gb-2014-15-3-r46

DOI

http://dx.doi.org/10.1186/gb-2014-15-3-r46

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030203790

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24580807


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