Ontology type: schema:ScholarlyArticle Open Access: True
2008-01-11
AUTHORSBrian J Haas, Steven L Salzberg, Wei Zhu, Mihaela Pertea, Jonathan E Allen, Joshua Orvis, Owen White, C Robin Buell, Jennifer R Wortman
ABSTRACTEVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program to Assemble Spliced Alignments (PASA), yields a comprehensive, configurable annotation system that predicts protein-coding genes and alternatively spliced isoforms. Our experiments on both rice and human genome sequences demonstrate that EVM produces automated gene structure annotation approaching the quality of manual curation. More... »
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DOIhttp://dx.doi.org/10.1186/gb-2008-9-1-r7
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/18190707
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