Prolinks: a database of protein functional linkages derived from coevolution View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2004-04-16

AUTHORS

Peter M Bowers, Matteo Pellegrini, Mike J Thompson, Joe Fierro, Todd O Yeates, David Eisenberg

ABSTRACT

The advent of whole-genome sequencing has led to methods that infer protein function and linkages. We have combined four such algorithms (phylogenetic profile, Rosetta Stone, gene neighbor and gene cluster) in a single database - Prolinks - that spans 83 organisms and includes 10 million high-confidence links. The Proteome Navigator tool allows users to browse predicted linkage networks interactively, providing accompanying annotation from public databases. The Prolinks database and the Proteome Navigator tool are available for use online at http://dip.doe-mbi.ucla.edu/pronav. More... »

PAGES

r35

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/gb-2004-5-5-r35

DOI

http://dx.doi.org/10.1186/gb-2004-5-5-r35

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052229286

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15128449


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