Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-04

AUTHORS

A Daniel Martin, Barbara K Smith, Paul D Davenport, Eloise Harman, Ricardo J Gonzalez-Rothi, Maher Baz, A Joseph Layon, Michael J Banner, Lawrence J Caruso, Harsha Deoghare, Tseng-Tien Huang, Andrea Gabrielli

ABSTRACT

INTRODUCTION: Most patients are readily liberated from mechanical ventilation (MV) support, however, 10% - 15% of patients experience failure to wean (FTW). FTW patients account for approximately 40% of all MV days and have significantly worse clinical outcomes. MV induced inspiratory muscle weakness has been implicated as a contributor to FTW and recent work has documented inspiratory muscle weakness in humans supported with MV. METHODS: We conducted a single center, single-blind, randomized controlled trial to test whether inspiratory muscle strength training (IMST) would improve weaning outcome in FTW patients. Of 129 patients evaluated for participation, 69 were enrolled and studied. 35 subjects were randomly assigned to the IMST condition and 34 to the SHAM treatment. IMST was performed with a threshold inspiratory device, set at the highest pressure tolerated and progressed daily. SHAM training provided a constant, low inspiratory pressure load. Subjects completed 4 sets of 6-10 training breaths, 5 days per week. Subjects also performed progressively longer breathing trials daily per protocol. The weaning criterion was 72 consecutive hours without MV support. Subjects were blinded to group assignment, and were treated until weaned or 28 days. RESULTS: Groups were comparable on demographic and clinical variables at baseline. The IMST and SHAM groups respectively received 41.9 ± 25.5 vs. 47.3 ± 33.0 days of MV support prior to starting intervention, P = 0.36. The IMST and SHAM groups participated in 9.7 ± 4.0 and 11.0 ± 4.8 training sessions, respectively, P = 0.09. The SHAM group's pre to post-training maximal inspiratory pressure (MIP) change was not significant (-43.5 ± 17.8 vs. -45.1 ± 19.5 cm H2O, P = 0.39), while the IMST group's MIP increased (-44.4 ± 18.4 vs. -54.1 ± 17.8 cm H2O, P < 0.0001). There were no adverse events observed during IMST or SHAM treatments. Twenty-five of 35 IMST subjects weaned (71%, 95% confidence interval (CI) = 55% to 84%), while 16 of 34 (47%, 95% CI = 31% to 63%) SHAM subjects weaned, P = .039. The number of patients needed to be treated for effect was 4 (95% CI = 2 to 80). CONCLUSIONS: An IMST program can lead to increased MIP and improved weaning outcome in FTW patients compared to SHAM treatment. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00419458. More... »

PAGES

r84

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/cc10081

DOI

http://dx.doi.org/10.1186/cc10081

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010204921

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21385346


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breathing Exercises", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Muscle Strength", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Program Evaluation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Respiratory Insufficiency", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Respiratory Muscles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Single-Blind Method", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ventilator Weaning", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Physical Therapy, University of Florida, 1600 South West Archer Road, PO Box 100154, FL 32610, Gainesville, USA", 
            "Department of Anesthesiology, Division of Critical Care Medicine, University of Florida, 1600 South West Archer Road, PO Box 100254, FL, 32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martin", 
        "givenName": "A Daniel", 
        "id": "sg:person.01171750166.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171750166.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Physical Therapy, University of Florida, 1600 South West Archer Road, PO Box 100154, FL 32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Smith", 
        "givenName": "Barbara K", 
        "id": "sg:person.0673040512.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673040512.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Physiological Sciences, University of Florida, 1600 South West Archer Road, PO Box 100144, FL32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Davenport", 
        "givenName": "Paul D", 
        "id": "sg:person.01251223723.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251223723.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine University of Florida, 1600 South West Archer Road, PO Box 100225, FL32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Harman", 
        "givenName": "Eloise", 
        "id": "sg:person.014231303041.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014231303041.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine University of Florida, 1600 South West Archer Road, PO Box 100225, FL32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonzalez-Rothi", 
        "givenName": "Ricardo J", 
        "id": "sg:person.0704126540.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704126540.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine University of Florida, 1600 South West Archer Road, PO Box 100225, FL32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Baz", 
        "givenName": "Maher", 
        "id": "sg:person.01012646160.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012646160.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine University of Florida, 1600 South West Archer Road, PO Box 100225, FL32610, Gainesville, USA", 
            "Department of Anesthesiology, Division of Critical Care Medicine, University of Florida, 1600 South West Archer Road, PO Box 100254, FL, 32610, Gainesville, USA", 
            "Department of Surgery, University of Florida, 1600 South West Archer Road, PO Box 100129, FL32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Layon", 
        "givenName": "A Joseph", 
        "id": "sg:person.01052161444.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052161444.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Anesthesiology, Division of Critical Care Medicine, University of Florida, 1600 South West Archer Road, PO Box 100254, FL, 32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Banner", 
        "givenName": "Michael J", 
        "id": "sg:person.01367104001.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367104001.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Anesthesiology, Division of Critical Care Medicine, University of Florida, 1600 South West Archer Road, PO Box 100254, FL, 32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Caruso", 
        "givenName": "Lawrence J", 
        "id": "sg:person.0620337360.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620337360.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Physical Therapy, University of Florida, 1600 South West Archer Road, PO Box 100154, FL 32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Deoghare", 
        "givenName": "Harsha", 
        "id": "sg:person.01367133236.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367133236.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Physical Therapy, University of Florida, 1600 South West Archer Road, PO Box 100154, FL 32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Huang", 
        "givenName": "Tseng-Tien", 
        "id": "sg:person.01175611266.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175611266.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Florida", 
          "id": "https://www.grid.ac/institutes/grid.15276.37", 
          "name": [
            "Department of Anesthesiology, Division of Critical Care Medicine, University of Florida, 1600 South West Archer Road, PO Box 100254, FL, 32610, Gainesville, USA", 
            "Department of Surgery, University of Florida, 1600 South West Archer Road, PO Box 100129, FL32610, Gainesville, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gabrielli", 
        "givenName": "Andrea", 
        "id": "sg:person.01026344741.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026344741.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1164/ajrccm.158.2.9710084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002438023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01694771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003513559", 
          "https://doi.org/10.1007/bf01694771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01694771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003513559", 
          "https://doi.org/10.1007/bf01694771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01694771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003513559", 
          "https://doi.org/10.1007/bf01694771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-007-0866-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003753615", 
          "https://doi.org/10.1007/s00134-007-0866-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-007-0866-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003753615", 
          "https://doi.org/10.1007/s00134-007-0866-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.rmed.2010.02.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004529596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc7927", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007573424", 
          "https://doi.org/10.1186/cc7927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1590/s1807-59322005000600009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008766912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.161.4.9812160", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008840411"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.107.2.500", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008924453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.122.1.192", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010183744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.122.1.192", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010183744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201002-0234oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012577923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.296.15.1851", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012944333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005768-200011000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013396487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005768-200011000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013396487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.164.9.2011150", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013446028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199105233242101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014346606"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.108.2.482", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015703297"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1067/mhl.2002.122840", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015894082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2007.140855", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017527864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(88)80585-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018127745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200503-356oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018661443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-003-1688-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019570789", 
          "https://doi.org/10.1007/s00134-003-1688-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7861/clinmedicine.9-5-448", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020124947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.115.4.1096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022138381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.115.4.1096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022138381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1513/pats.200611-159cc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022533572"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.2004.026500", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024153867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.2004.026500", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024153867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc9094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024386586", 
          "https://doi.org/10.1186/cc9094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc9094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024386586", 
          "https://doi.org/10.1186/cc9094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa070447", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025135202"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.164.7.2005081", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025351540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-7793.2000.00493.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030366467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-7793.2001.0277k.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030465715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033127231", 
          "https://doi.org/10.1186/cc112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1308/003588410x12771863936648", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033391204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200503-403oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035501674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.200503-403oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035501674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.162.5.9906033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036813519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.1980.sp013496", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038547342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/copd.s2108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038947291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.06-1081", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043466939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcrc.2008.10.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046967463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1536/ihj.46.819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047381089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1536/ihj.46.819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047381089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201004-0670oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047477148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcrc.2009.01.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048291231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.05.00105204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048646585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e3181691a49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049069269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e3181691a49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049069269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31816536f7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049757877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31816536f7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049757877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005768-199806000-00033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060230458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005768-199806000-00033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060230458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005768-199806000-00033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060230458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ptj/83.2.171", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075230210"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080013182", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083277212", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-04", 
    "datePublishedReg": "2011-04-01", 
    "description": "INTRODUCTION: Most patients are readily liberated from mechanical ventilation (MV) support, however, 10% - 15% of patients experience failure to wean (FTW). FTW patients account for approximately 40% of all MV days and have significantly worse clinical outcomes. MV induced inspiratory muscle weakness has been implicated as a contributor to FTW and recent work has documented inspiratory muscle weakness in humans supported with MV.\nMETHODS: We conducted a single center, single-blind, randomized controlled trial to test whether inspiratory muscle strength training (IMST) would improve weaning outcome in FTW patients. Of 129 patients evaluated for participation, 69 were enrolled and studied. 35 subjects were randomly assigned to the IMST condition and 34 to the SHAM treatment. IMST was performed with a threshold inspiratory device, set at the highest pressure tolerated and progressed daily. SHAM training provided a constant, low inspiratory pressure load. Subjects completed 4 sets of 6-10 training breaths, 5 days per week. Subjects also performed progressively longer breathing trials daily per protocol. The weaning criterion was 72 consecutive hours without MV support. Subjects were blinded to group assignment, and were treated until weaned or 28 days.\nRESULTS: Groups were comparable on demographic and clinical variables at baseline. The IMST and SHAM groups respectively received 41.9 \u00b1 25.5 vs. 47.3 \u00b1 33.0 days of MV support prior to starting intervention, P = 0.36. The IMST and SHAM groups participated in 9.7 \u00b1 4.0 and 11.0 \u00b1 4.8 training sessions, respectively, P = 0.09. The SHAM group's pre to post-training maximal inspiratory pressure (MIP) change was not significant (-43.5 \u00b1 17.8 vs. -45.1 \u00b1 19.5 cm H2O, P = 0.39), while the IMST group's MIP increased (-44.4 \u00b1 18.4 vs. -54.1 \u00b1 17.8 cm H2O, P < 0.0001). There were no adverse events observed during IMST or SHAM treatments. Twenty-five of 35 IMST subjects weaned (71%, 95% confidence interval (CI) = 55% to 84%), while 16 of 34 (47%, 95% CI = 31% to 63%) SHAM subjects weaned, P = .039. The number of patients needed to be treated for effect was 4 (95% CI = 2 to 80).\nCONCLUSIONS: An IMST program can lead to increased MIP and improved weaning outcome in FTW patients compared to SHAM treatment.\nTRIAL REGISTRATION: ClinicalTrials.gov: NCT00419458.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1186/cc10081", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2684441", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2526688", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1117766", 
        "issn": [
          "1364-8535", 
          "1466-609X"
        ], 
        "name": "Critical Care", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial", 
    "pagination": "r84", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "309e46ac84bf645f918b1e171ce7a7d60d41473e972881d93ca28316610789aa"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21385346"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9801902"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1186/cc10081"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1010204921"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1186/cc10081", 
      "https://app.dimensions.ai/details/publication/pub.1010204921"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T02:15", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000536.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1186%2Fcc10081"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1186/cc10081'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1186/cc10081'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1186/cc10081'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1186/cc10081'


 

This table displays all metadata directly associated to this object as RDF triples.

351 TRIPLES      21 PREDICATES      89 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1186/cc10081 schema:about N0185ce637bce45a0bf2e8397df9fee2e
2 N39eee107d80e48f8a5574c909dcd1276
3 N52b7c9a334c54a869288fc98ae0092f5
4 N52e1328665ff4d129a300b6700fd002f
5 N59ce93814f8d4a0eb6edf4ac3c9f8072
6 N5a3aa4d7b60345adacbe6606393259be
7 N6da1a07e729f4b22834f326982e90c76
8 N9770e90f09d746fa9abe3f7ed5fc452a
9 N97856cb1ad52466b9f04dc93a4878607
10 Na4f8aea709a940fc88439266a07bbdfe
11 Nec244e60682a4d5db61332124ccdd596
12 Necc7f4568cae4b9cbc48386459c11032
13 Ned86c440cff94f9e8715f93f0bb46dd3
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author N3f9130ee64f24496bcdabeac6c505c61
17 schema:citation sg:pub.10.1007/bf01694771
18 sg:pub.10.1007/s00134-003-1688-0
19 sg:pub.10.1007/s00134-007-0866-x
20 sg:pub.10.1186/cc112
21 sg:pub.10.1186/cc7927
22 sg:pub.10.1186/cc9094
23 https://app.dimensions.ai/details/publication/pub.1080013182
24 https://app.dimensions.ai/details/publication/pub.1083277212
25 https://doi.org/10.1001/jama.296.15.1851
26 https://doi.org/10.1016/j.jcrc.2008.10.013
27 https://doi.org/10.1016/j.jcrc.2009.01.007
28 https://doi.org/10.1016/j.rmed.2010.02.019
29 https://doi.org/10.1016/s0022-3476(88)80585-7
30 https://doi.org/10.1056/nejm199105233242101
31 https://doi.org/10.1056/nejmoa070447
32 https://doi.org/10.1067/mhl.2002.122840
33 https://doi.org/10.1093/ptj/83.2.171
34 https://doi.org/10.1097/00005768-199806000-00033
35 https://doi.org/10.1097/00005768-200011000-00007
36 https://doi.org/10.1097/ccm.0b013e31816536f7
37 https://doi.org/10.1097/ccm.0b013e3181691a49
38 https://doi.org/10.1111/j.1469-7793.2000.00493.x
39 https://doi.org/10.1111/j.1469-7793.2001.0277k.x
40 https://doi.org/10.1113/jphysiol.1980.sp013496
41 https://doi.org/10.1113/jphysiol.2007.140855
42 https://doi.org/10.1136/thx.2004.026500
43 https://doi.org/10.1164/ajrccm.158.2.9710084
44 https://doi.org/10.1164/ajrccm.161.4.9812160
45 https://doi.org/10.1164/ajrccm.162.5.9906033
46 https://doi.org/10.1164/ajrccm.164.7.2005081
47 https://doi.org/10.1164/ajrccm.164.9.2011150
48 https://doi.org/10.1164/rccm.200503-356oc
49 https://doi.org/10.1164/rccm.200503-403oc
50 https://doi.org/10.1164/rccm.201002-0234oc
51 https://doi.org/10.1164/rccm.201004-0670oc
52 https://doi.org/10.1183/09031936.05.00105204
53 https://doi.org/10.1308/003588410x12771863936648
54 https://doi.org/10.1378/chest.06-1081
55 https://doi.org/10.1378/chest.107.2.500
56 https://doi.org/10.1378/chest.108.2.482
57 https://doi.org/10.1378/chest.115.4.1096
58 https://doi.org/10.1378/chest.122.1.192
59 https://doi.org/10.1513/pats.200611-159cc
60 https://doi.org/10.1536/ihj.46.819
61 https://doi.org/10.1590/s1807-59322005000600009
62 https://doi.org/10.2147/copd.s2108
63 https://doi.org/10.7861/clinmedicine.9-5-448
64 schema:datePublished 2011-04
65 schema:datePublishedReg 2011-04-01
66 schema:description INTRODUCTION: Most patients are readily liberated from mechanical ventilation (MV) support, however, 10% - 15% of patients experience failure to wean (FTW). FTW patients account for approximately 40% of all MV days and have significantly worse clinical outcomes. MV induced inspiratory muscle weakness has been implicated as a contributor to FTW and recent work has documented inspiratory muscle weakness in humans supported with MV. METHODS: We conducted a single center, single-blind, randomized controlled trial to test whether inspiratory muscle strength training (IMST) would improve weaning outcome in FTW patients. Of 129 patients evaluated for participation, 69 were enrolled and studied. 35 subjects were randomly assigned to the IMST condition and 34 to the SHAM treatment. IMST was performed with a threshold inspiratory device, set at the highest pressure tolerated and progressed daily. SHAM training provided a constant, low inspiratory pressure load. Subjects completed 4 sets of 6-10 training breaths, 5 days per week. Subjects also performed progressively longer breathing trials daily per protocol. The weaning criterion was 72 consecutive hours without MV support. Subjects were blinded to group assignment, and were treated until weaned or 28 days. RESULTS: Groups were comparable on demographic and clinical variables at baseline. The IMST and SHAM groups respectively received 41.9 ± 25.5 vs. 47.3 ± 33.0 days of MV support prior to starting intervention, P = 0.36. The IMST and SHAM groups participated in 9.7 ± 4.0 and 11.0 ± 4.8 training sessions, respectively, P = 0.09. The SHAM group's pre to post-training maximal inspiratory pressure (MIP) change was not significant (-43.5 ± 17.8 vs. -45.1 ± 19.5 cm H2O, P = 0.39), while the IMST group's MIP increased (-44.4 ± 18.4 vs. -54.1 ± 17.8 cm H2O, P < 0.0001). There were no adverse events observed during IMST or SHAM treatments. Twenty-five of 35 IMST subjects weaned (71%, 95% confidence interval (CI) = 55% to 84%), while 16 of 34 (47%, 95% CI = 31% to 63%) SHAM subjects weaned, P = .039. The number of patients needed to be treated for effect was 4 (95% CI = 2 to 80). CONCLUSIONS: An IMST program can lead to increased MIP and improved weaning outcome in FTW patients compared to SHAM treatment. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00419458.
67 schema:genre research_article
68 schema:inLanguage en
69 schema:isAccessibleForFree true
70 schema:isPartOf N71282b7fe37d4c2792662500b45f7e53
71 Ne692343e50a74ce3ae35f046e3d4e170
72 sg:journal.1117766
73 schema:name Inspiratory muscle strength training improves weaning outcome in failure to wean patients: a randomized trial
74 schema:pagination r84
75 schema:productId N0092d776e1784aa4a4d02fde98d06eff
76 N038d1d01955140079fa4224f12fd770c
77 N2e46b9fca3e1436a8526a79bc7f0d434
78 N9d47876725e14b70bdb8d31c32777476
79 Nc9b393de85644207a026f808936f4c49
80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010204921
81 https://doi.org/10.1186/cc10081
82 schema:sdDatePublished 2019-04-11T02:15
83 schema:sdLicense https://scigraph.springernature.com/explorer/license/
84 schema:sdPublisher Ndb7aaf56e1c94ab99c0068b9d2aaeb9f
85 schema:url http://link.springer.com/10.1186%2Fcc10081
86 sgo:license sg:explorer/license/
87 sgo:sdDataset articles
88 rdf:type schema:ScholarlyArticle
89 N0092d776e1784aa4a4d02fde98d06eff schema:name pubmed_id
90 schema:value 21385346
91 rdf:type schema:PropertyValue
92 N0185ce637bce45a0bf2e8397df9fee2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Middle Aged
94 rdf:type schema:DefinedTerm
95 N038d1d01955140079fa4224f12fd770c schema:name readcube_id
96 schema:value 309e46ac84bf645f918b1e171ce7a7d60d41473e972881d93ca28316610789aa
97 rdf:type schema:PropertyValue
98 N2e46b9fca3e1436a8526a79bc7f0d434 schema:name dimensions_id
99 schema:value pub.1010204921
100 rdf:type schema:PropertyValue
101 N31a62d15f7eb422c9048cf951c087d1e rdf:first sg:person.01251223723.43
102 rdf:rest N3d9ca401050d4462b97f12d8408361fd
103 N353681f89d5b47faae3a77dc38da2d0c rdf:first sg:person.01367133236.11
104 rdf:rest N6f934c50e1914c6eb38fe60d19204dd6
105 N39eee107d80e48f8a5574c909dcd1276 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Aged
107 rdf:type schema:DefinedTerm
108 N3d9ca401050d4462b97f12d8408361fd rdf:first sg:person.014231303041.79
109 rdf:rest Nc637a2300a75420eaa7813a277602afc
110 N3f9130ee64f24496bcdabeac6c505c61 rdf:first sg:person.01171750166.99
111 rdf:rest N6d73c49857344ffbaede0823b6080fe7
112 N52b7c9a334c54a869288fc98ae0092f5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Female
114 rdf:type schema:DefinedTerm
115 N52e1328665ff4d129a300b6700fd002f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Treatment Outcome
117 rdf:type schema:DefinedTerm
118 N59ce93814f8d4a0eb6edf4ac3c9f8072 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Muscle Strength
120 rdf:type schema:DefinedTerm
121 N5a3aa4d7b60345adacbe6606393259be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Respiratory Muscles
123 rdf:type schema:DefinedTerm
124 N6065f370406540b194061d80a613f7b6 rdf:first sg:person.01026344741.05
125 rdf:rest rdf:nil
126 N63478541c7bb409d9c6fce3073589ea8 rdf:first sg:person.01012646160.14
127 rdf:rest N90fc8e5d32e24bfca7106601814aa0c3
128 N6d73c49857344ffbaede0823b6080fe7 rdf:first sg:person.0673040512.58
129 rdf:rest N31a62d15f7eb422c9048cf951c087d1e
130 N6da1a07e729f4b22834f326982e90c76 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Breathing Exercises
132 rdf:type schema:DefinedTerm
133 N6f934c50e1914c6eb38fe60d19204dd6 rdf:first sg:person.01175611266.49
134 rdf:rest N6065f370406540b194061d80a613f7b6
135 N71282b7fe37d4c2792662500b45f7e53 schema:issueNumber 2
136 rdf:type schema:PublicationIssue
137 N84e4cef6d4f04e5aaae1dc5aeb76daa5 rdf:first sg:person.0620337360.57
138 rdf:rest N353681f89d5b47faae3a77dc38da2d0c
139 N90fc8e5d32e24bfca7106601814aa0c3 rdf:first sg:person.01052161444.74
140 rdf:rest Nf9790baa55f64c40ba7e3e82d9b29360
141 N9770e90f09d746fa9abe3f7ed5fc452a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Ventilator Weaning
143 rdf:type schema:DefinedTerm
144 N97856cb1ad52466b9f04dc93a4878607 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Program Evaluation
146 rdf:type schema:DefinedTerm
147 N9d47876725e14b70bdb8d31c32777476 schema:name doi
148 schema:value 10.1186/cc10081
149 rdf:type schema:PropertyValue
150 Na4f8aea709a940fc88439266a07bbdfe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Male
152 rdf:type schema:DefinedTerm
153 Nc637a2300a75420eaa7813a277602afc rdf:first sg:person.0704126540.14
154 rdf:rest N63478541c7bb409d9c6fce3073589ea8
155 Nc9b393de85644207a026f808936f4c49 schema:name nlm_unique_id
156 schema:value 9801902
157 rdf:type schema:PropertyValue
158 Ndb7aaf56e1c94ab99c0068b9d2aaeb9f schema:name Springer Nature - SN SciGraph project
159 rdf:type schema:Organization
160 Ne692343e50a74ce3ae35f046e3d4e170 schema:volumeNumber 15
161 rdf:type schema:PublicationVolume
162 Nec244e60682a4d5db61332124ccdd596 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Respiratory Insufficiency
164 rdf:type schema:DefinedTerm
165 Necc7f4568cae4b9cbc48386459c11032 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Humans
167 rdf:type schema:DefinedTerm
168 Ned86c440cff94f9e8715f93f0bb46dd3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Single-Blind Method
170 rdf:type schema:DefinedTerm
171 Nf9790baa55f64c40ba7e3e82d9b29360 rdf:first sg:person.01367104001.13
172 rdf:rest N84e4cef6d4f04e5aaae1dc5aeb76daa5
173 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
174 schema:name Medical and Health Sciences
175 rdf:type schema:DefinedTerm
176 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
177 schema:name Clinical Sciences
178 rdf:type schema:DefinedTerm
179 sg:grant.2526688 http://pending.schema.org/fundedItem sg:pub.10.1186/cc10081
180 rdf:type schema:MonetaryGrant
181 sg:grant.2684441 http://pending.schema.org/fundedItem sg:pub.10.1186/cc10081
182 rdf:type schema:MonetaryGrant
183 sg:journal.1117766 schema:issn 1364-8535
184 1466-609X
185 schema:name Critical Care
186 rdf:type schema:Periodical
187 sg:person.01012646160.14 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
188 schema:familyName Baz
189 schema:givenName Maher
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012646160.14
191 rdf:type schema:Person
192 sg:person.01026344741.05 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
193 schema:familyName Gabrielli
194 schema:givenName Andrea
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026344741.05
196 rdf:type schema:Person
197 sg:person.01052161444.74 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
198 schema:familyName Layon
199 schema:givenName A Joseph
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052161444.74
201 rdf:type schema:Person
202 sg:person.01171750166.99 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
203 schema:familyName Martin
204 schema:givenName A Daniel
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171750166.99
206 rdf:type schema:Person
207 sg:person.01175611266.49 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
208 schema:familyName Huang
209 schema:givenName Tseng-Tien
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175611266.49
211 rdf:type schema:Person
212 sg:person.01251223723.43 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
213 schema:familyName Davenport
214 schema:givenName Paul D
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251223723.43
216 rdf:type schema:Person
217 sg:person.01367104001.13 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
218 schema:familyName Banner
219 schema:givenName Michael J
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367104001.13
221 rdf:type schema:Person
222 sg:person.01367133236.11 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
223 schema:familyName Deoghare
224 schema:givenName Harsha
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367133236.11
226 rdf:type schema:Person
227 sg:person.014231303041.79 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
228 schema:familyName Harman
229 schema:givenName Eloise
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014231303041.79
231 rdf:type schema:Person
232 sg:person.0620337360.57 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
233 schema:familyName Caruso
234 schema:givenName Lawrence J
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620337360.57
236 rdf:type schema:Person
237 sg:person.0673040512.58 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
238 schema:familyName Smith
239 schema:givenName Barbara K
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673040512.58
241 rdf:type schema:Person
242 sg:person.0704126540.14 schema:affiliation https://www.grid.ac/institutes/grid.15276.37
243 schema:familyName Gonzalez-Rothi
244 schema:givenName Ricardo J
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0704126540.14
246 rdf:type schema:Person
247 sg:pub.10.1007/bf01694771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003513559
248 https://doi.org/10.1007/bf01694771
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/s00134-003-1688-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019570789
251 https://doi.org/10.1007/s00134-003-1688-0
252 rdf:type schema:CreativeWork
253 sg:pub.10.1007/s00134-007-0866-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003753615
254 https://doi.org/10.1007/s00134-007-0866-x
255 rdf:type schema:CreativeWork
256 sg:pub.10.1186/cc112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033127231
257 https://doi.org/10.1186/cc112
258 rdf:type schema:CreativeWork
259 sg:pub.10.1186/cc7927 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007573424
260 https://doi.org/10.1186/cc7927
261 rdf:type schema:CreativeWork
262 sg:pub.10.1186/cc9094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024386586
263 https://doi.org/10.1186/cc9094
264 rdf:type schema:CreativeWork
265 https://app.dimensions.ai/details/publication/pub.1080013182 schema:CreativeWork
266 https://app.dimensions.ai/details/publication/pub.1083277212 schema:CreativeWork
267 https://doi.org/10.1001/jama.296.15.1851 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012944333
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/j.jcrc.2008.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046967463
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/j.jcrc.2009.01.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048291231
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/j.rmed.2010.02.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004529596
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1016/s0022-3476(88)80585-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018127745
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1056/nejm199105233242101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014346606
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1056/nejmoa070447 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025135202
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1067/mhl.2002.122840 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015894082
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1093/ptj/83.2.171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075230210
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1097/00005768-199806000-00033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060230458
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1097/00005768-200011000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013396487
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1097/ccm.0b013e31816536f7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049757877
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1097/ccm.0b013e3181691a49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049069269
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1111/j.1469-7793.2000.00493.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030366467
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1111/j.1469-7793.2001.0277k.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030465715
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1113/jphysiol.1980.sp013496 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038547342
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1113/jphysiol.2007.140855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017527864
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1136/thx.2004.026500 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024153867
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1164/ajrccm.158.2.9710084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002438023
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1164/ajrccm.161.4.9812160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008840411
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1164/ajrccm.162.5.9906033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036813519
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1164/ajrccm.164.7.2005081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025351540
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1164/ajrccm.164.9.2011150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013446028
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1164/rccm.200503-356oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1018661443
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1164/rccm.200503-403oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1035501674
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1164/rccm.201002-0234oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1012577923
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1164/rccm.201004-0670oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1047477148
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1183/09031936.05.00105204 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048646585
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1308/003588410x12771863936648 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033391204
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1378/chest.06-1081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043466939
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1378/chest.107.2.500 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008924453
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1378/chest.108.2.482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015703297
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1378/chest.115.4.1096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022138381
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1378/chest.122.1.192 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010183744
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1513/pats.200611-159cc schema:sameAs https://app.dimensions.ai/details/publication/pub.1022533572
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1536/ihj.46.819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047381089
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1590/s1807-59322005000600009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008766912
340 rdf:type schema:CreativeWork
341 https://doi.org/10.2147/copd.s2108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038947291
342 rdf:type schema:CreativeWork
343 https://doi.org/10.7861/clinmedicine.9-5-448 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020124947
344 rdf:type schema:CreativeWork
345 https://www.grid.ac/institutes/grid.15276.37 schema:alternateName University of Florida
346 schema:name Department of Anesthesiology, Division of Critical Care Medicine, University of Florida, 1600 South West Archer Road, PO Box 100254, FL, 32610, Gainesville, USA
347 Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine University of Florida, 1600 South West Archer Road, PO Box 100225, FL32610, Gainesville, USA
348 Department of Physical Therapy, University of Florida, 1600 South West Archer Road, PO Box 100154, FL 32610, Gainesville, USA
349 Department of Physiological Sciences, University of Florida, 1600 South West Archer Road, PO Box 100144, FL32610, Gainesville, USA
350 Department of Surgery, University of Florida, 1600 South West Archer Road, PO Box 100129, FL32610, Gainesville, USA
351 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...