Overdiagnosis and overtreatment of breast cancer: Overdiagnosis and overtreatment in service screening View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2005-12

AUTHORS

Eugenio Paci, Stephen Duffy

ABSTRACT

Screening mammography has been shown to be effective for reducing breast cancer mortality. According to screening theory, the first expected consequence of mammography screening is the detection of the disease at earlier stages and this diagnostic anticipation changes the population incidence curve, with an observed increase in incidence rates at earlier ages. It is unreasonable to expect that the age-specific incidence will ever return to pre-screening levels or to anticipate a significant reduction of incidence at older ages immediately after the first screening round. The interpretation of incidence trends, especially in the short term, is difficult. Methodology for quantification of overdiagnosis and statistical modelling based on service screening data is not well developed and few population-based studies are available. The overtreatment issue is discussed in terms of appropriateness of effective treatment considering the question of chemotherapy in very early stages and the use of breast conserving surgery. More... »

PAGES

266

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/bcr1339

DOI

http://dx.doi.org/10.1186/bcr1339

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042609520

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16457702


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