Adult mesenchymal stem cells and cell-based tissue engineering View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-02

AUTHORS

Rocky S Tuan, Genevieve Boland, Richard Tuli

ABSTRACT

The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues, including bone marrow stroma and a number of connective tissues, has provided exciting prospects for cell-based tissue engineering and regeneration. This review focuses on the biology of MSCs, including their differentiation potentials in vitro and in vivo, and the application of MSCs in tissue engineering. Our current understanding of MSCs lags behind that of other stem cell types, such as hematopoietic stem cells. Future research should aim to define the cellular and molecular fingerprints of MSCs and elucidate their endogenous role(s) in normal and abnormal tissue functions. More... »

PAGES

32

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1186/ar614

    DOI

    http://dx.doi.org/10.1186/ar614

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1023450118

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/12716446


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