Ontology type: schema:ScholarlyArticle Open Access: True
2013-09-25
AUTHORS ABSTRACTMost research in gout has concentrated on the proinflammatory mechanisms toexplain the inflammation that is generated when leucocytes are in contact withmonosodium urate crystals. However, the episodic nature of gout and the absenceof inflammation even when crystals are present suggest that there are naturalcounter-regulatory mechanisms to limit the inflammatory response. Gagné andcolleagues showed that myeloid inhibitory C-type lectin, a C-type lectininhibitory receptor expressed on neutrophils, modulates monosodium urate-inducedneutrophil responses in vitro. More... »
PAGES118
http://scigraph.springernature.com/pub.10.1186/ar4316
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/24063679
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