How to regulate neutrophils in gout View Full Text


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Article Info

DATE

2013-09-25

AUTHORS

Alexander So

ABSTRACT

Most research in gout has concentrated on the proinflammatory mechanisms toexplain the inflammation that is generated when leucocytes are in contact withmonosodium urate crystals. However, the episodic nature of gout and the absenceof inflammation even when crystals are present suggest that there are naturalcounter-regulatory mechanisms to limit the inflammatory response. Gagné andcolleagues showed that myeloid inhibitory C-type lectin, a C-type lectininhibitory receptor expressed on neutrophils, modulates monosodium urate-inducedneutrophil responses in vitro. More... »

PAGES

118

Identifiers

URI

http://scigraph.springernature.com/pub.10.1186/ar4316

DOI

http://dx.doi.org/10.1186/ar4316

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009664742

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24063679


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